JAMA - Journal of the American Medical Association




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Effect of Endovascular Treatment Alone vs Intravenous Alteplase Plus Endovascular Treatment on Functional Independence in Patients With Acute Ischemic Stroke

Wenjie Zi, MD1; Zhongming Qiu, MD1,2; Fengli Li, MD1; Hongfei Sang, MD1,3; Deping Wu, MD1,4; Weidong Luo, MD1; Shuai Liu, MD1; Junjie Yuan, MD1; Jiaxing Song, MD1; Zhonghua Shi, MD5; Wenguo Huang, MD6; Min Zhang, MS6; Wenhua Liu, MD7; Zhangbao Guo, MS7; Tao Qiu, MD8; Qiang Shi, MS8; Peiyang Zhou, MD9; Li Wang, MD10; Xinmin Fu, MD11; Shudong Liu, MD12; Shiquan Yang, MD13; Shuai Zhang, MD14; Zhiming Zhou, MD15; Xianjun Huang, MD15; Yan Wang, MD16; Jun Luo, MS17; Yongjie Bai, MD18; Min Zhang, MS19; Youlin Wu, MS20; Guoyong Zeng, MD21; Yue Wan, MD22; Changming Wen, MD23; Hongbin Wen, MD24; Wentong Ling, MS25; Zhuo Chen, MS26; Miao Peng, MS27; Zhibing Ai, MD28; Fuqiang Guo, MD29; Huagang Li, MD30; Jing Guo, MS31; Haitao Guan, MD32; Zhiyi Wang, MS33; Yong Liu, MS34; Jie Pu, MD35; Zhen Wang, MD36; Hansheng Liu, MD1; Luming Chen, MD1; Jiacheng Huang, MD1; Guoqiang Yang, MD1; Zili Gong, MD1; Jie Shuai, MD1; Raul G. Nogueira, MD37; Qingwu Yang, MD, PhD1; for the DEVT Trial Investigators

doi : 10.1001/jama.2020.23523

JAMA. 2021;325(3):234-243

For patients with large vessel occlusion strokes, it is unknown whether endovascular treatment alone compared with intravenous thrombolysis plus endovascular treatment (standard treatment) can achieve similar functional outcomes.

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Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke

Kentaro Suzuki, MD, PhD1; Yuji Matsumaru, MD, PhD2; Masataka Takeuchi, MD3; Masafumi Morimoto, MD, PhD4; Ryuzaburo Kanazawa, MD, PhD5; Yohei Takayama, MD6; Yuki Kamiya, MD, PhD7; Keigo Shigeta, MD, PhD8; Seiji Okubo, MD, PhD9; Mikito Hayakawa, MD2; Norihiro Ishii, MD, PhD10; Yorio Koguchi, MD, PhD11; Tomoji Takigawa, MD, PhD12; Masato Inoue, MD, PhD13; Hiromichi Naito, MD14; Takahiro Ota, MD, PhD15; Teruyuki Hirano, MD, PhD16; Noriyuki Kato, MD, PhD17; Toshihiro Ueda, MD, PhD18; Yasuyuki Iguchi, MD, PhD19; Kazunori Akaji, MD, PhD20; Wataro Tsuruta, MD, PhD21; Kazunori Miki, MD, PhD22; Shigeru Fujimoto, MD, PhD23; Tetsuhiro Higashida, MD, PhD5; Mitsuhiro Iwasaki, MD4; Junya Aoki, MD, PhD1; Yasuhiro Nishiyama, MD, PhD1; Toshiaki Otsuka, MD, PhD24; Kazumi Kimura, MD, PhD1; for the SKIP Study Investigators

doi : 10.1001/jama.2020.23522

JAMA. 2021;325(3):244-253

Whether intravenous thrombolysis is needed in combination with mechanical thrombectomy in patients with acute large vessel occlusion stroke is unclear.

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Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19

Renato D. Lopes, MD, PhD1,2,3,4; Ariane V. S. Macedo, MD, MSc1,5,6; Pedro G. M. de Barros E Silva, MD, PhD3; Renata J. Moll-Bernardes, MD, PhD1; Tiago M. dos Santos, MSc3,7; Lilian Mazza, RT3; André Feldman, MD, PhD1,8; Guilherme D’Andréa Saba Arruda, MD1,9; Den?lson C. de Albuquerque, MD, PhD1,10; Angelina S. Camiletti, RN, MSc1,4; Andréa S. de Sousa, MD, PhD1,11,12; Thiago C. de Paula, MD5; Karla G. D. Giusti, MD13; Rafael A. M. Domiciano, MD8; M?rcia M. Noya-Rabelo, MD, MHS, PhD14,15; Alan M. Hamilton, MD14; Vitor A. Loures, MD8; Rodrigo M. Dion?sio, MD16; Thyago A. B. Furquim, MD16; F?bio A. De Luca, MD, MBA, PhD17; ?talo B. dos Santos Sousa, MD17; Bruno S. Bandeira, MD18; Cleverson N. Zukowski, MD, PhD19; Ricardo G. G. de Oliveira, MD20; Noara B. Ribeiro, MD21; Jeffer L. de Moraes, MD22; Jo?o L. F. Petriz, MD, MHS, PhD23; Adriana M. Pimentel, MD, PhD24; Jacqueline S. Miranda, MD25; B?rbara E. de Jesus Abufaiad, MD26; C. Michael Gibson, MD27; Christopher B. Granger, MD2; John H. Alexander, MD, MHS2; Olga F. de Souza, MD, PhD1,4,25; for the BRACE CORONA Investigators

doi : 10.1001/jama.2020.25864

JAMA. 2021;325(3):254-264

It is unknown whether angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) have a positive, neutral, or negative effect on clinical outcomes in patients with coronavirus disease 2019 (COVID-19).

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Readmission and Death After Initial Hospital Discharge Among Patients With COVID-19 in a Large Multihospital System

John P. Donnelly, PhD1; Xiao Qing Wang, MPH2; Theodore J. Iwashyna, MD, PhD3; Hallie C. Prescott, MD, MSc3

doi : 10.1001/jama.2020.21465

JAMA. 2021;325(3):304-306

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Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons

US Preventive Services Task Force

doi : 10.1001/jama.2020.25019

JAMA. 2021;325(3):265-279

Tobacco use is the leading preventable cause of disease, disability, and death in the US. In 2014, it was estimated that 480?000 deaths annually are attributed to cigarette smoking, including second hand smoke exposure. Smoking during pregnancy can increase the risk of numerous adverse pregnancy outcomes (eg, miscarriage and congenital anomalies) and complications in the offspring (including sudden infant death syndrome and impaired lung function in childhood). In 2019, an estimated 50.6 million US adults (20.8% of the adult population) used tobacco; 14.0% of the US adult population currently smoked cigarettes and 4.5% of the adult population used electronic cigarettes (e-cigarettes). Among pregnant US women who gave birth in 2016, 7.2% reported smoking cigarettes while pregnant.

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Interventions for Tobacco Cessation in Adults, Including Pregnant Persons

Carrie D. Patnode, PhD, MPH1; Jillian T. Henderson, PhD, MPH1; Erin L. Coppola, MPH1; Joy Melnikow, MD, MPH2; Shauna Durbin, MPH2; Rachel G. Thomas, MPH1

doi : 10.1001/jama.2020.23541

JAMA. 2021;325(3):280-298

It has been estimated that in 2018 nearly 20% of adults in the US were currently using a tobacco product.

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The Language of Health Care Reform

Larry Levitt, MPP1

doi : 10.1001/jama.2020.25717

JAMA. 2021;325(3):215-216

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Executive Action to Expand Health Services in the Biden Administration

Timothy M. Westmoreland, JD1; M. Gregg Bloche, MD, JD1; Lawrence O. Gostin, JD2

doi : 10.1001/jama.2020.25888

JAMA. 2021;325(3):217-218

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The Ethics of Continuing Placebo in SARS-CoV-2 Vaccine Trials

Annette Rid, MD1; Marc Lipsitch, DPhil2; Franklin G. Miller, PhD3

doi : 10.1001/jama.2020.25053

JAMA. 2021;325(3):219-220

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Evaluating SARS-CoV-2 Vaccines After Emergency Use Authorization or Licensing of Initial Candidate Vaccines

Steven Joffe, MD, MPH1

doi : 10.1001/jama.2020.25127

JAMA. 2021;325(3):221-222

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Public Health Messaging in an Era of Social Media

Raina M. Merchant, MD, MSHP1,2; Eugenia C. South, MD, MSHP1,3; Nicole Lurie, MD, MSPH4,5

doi : 10.1001/jama.2020.24514

JAMA. 2021;325(3):223-224

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Root Cause Analysis

Megan Paulsen, MD1

doi : 10.1001/jama.2020.24911

JAMA. 2021;325(3):225-226

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Health Care Is a Right, Not a Privilege

Howard Bauchner, MD1; Phil B. Fontanarosa, MD, MBA2; Karen Joynt Maddox, MD, MPH3,4

doi : 10.1001/jama.2020.23915

JAMA. 2021;325(3):227-228

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Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke

Jeffrey L. Saver, MD1,2; Opeolu Adeoye, MD, MS3

doi : 10.1001/jama.2020.22388

JAMA. 2021;325(3):229-231

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A Comprehensive Approach to Increase Adult Tobacco Cessation

Brenna VanFrank, MD, MSPH1; Letitia Presley-Cantrell, PhD1

doi : 10.1001/jama.2020.23608

JAMA. 2021;325(3):232-233

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Safe Central Venous Access in an Overburdened Health System

Karen Woo, MD, MS1; David Rigberg, MD1; Peter F. Lawrence, MD1

doi : 10.1001/jama.2020.20361

JAMA. 2021;325(3):299-300

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Initiating Pharmacologic Treatment in Tobacco-Dependent Adults

Atul Jain, MD, MS1; Andrew M. Davis, MD, MPH2

doi : 10.1001/jama.2020.24790

JAMA. 2021;325(3):301-302

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COVID-19 Conspiracies and Beyond: How Physicians Can Deal With Patients’ Misinformation

Jennifer Abbasi

doi : 10.1001/jama.2020.22018

JAMA. 2021;325(3):208-210

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New Guidance for Type 1 Diabetes Continuous Glucose Monitoring Use During Exercise

Mary Chris Jaklevic, MSJ

doi : 10.1001/jama.2020.22890

JAMA. 2021;325(3):211-212

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First Drug Approved for Rare Genetic Disorder Affecting Kidneys

Mary Chris Jaklevic, MSJ

doi : 10.1001/jama.2020.26382

JAMA. 2021;325(3):214

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Avoid Masks With Metal During Magnetic Resonance Imaging

Mary Chris Jaklevic, MSJ

doi : 10.1001/jama.2020.25687

JAMA. 2021;325(3):214

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Imaging Drug for Prostate Cancer

Mary Chris Jaklevic, MSJ

doi : 10.1001/jama.2020.26384

JAMA. 2021;325(3):214

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WHO Launches Global Push to Eliminate Cervical Cancer

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2020.25668

JAMA. 2021;325(3):213

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Monthly Malaria Prophylaxis Cuts Child Deaths in Sub-Saharan Africa

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2020.26584

JAMA. 2021;325(3):213

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Drop in Vaccination Causes Surge in Global Measles Cases, Deaths

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2020.26586

JAMA. 2021;325(3):213

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Spraying Cotton in Bolivar County, Mississippi, the Summer Following My First Year of Medical School

Doug Hester, MD1

doi : 10.1001/jama.2020.20959

JAMA. 2021;325(3):310

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The Cause of Cancer

doi : 10.1001/jama.2020.17762

JAMA. 2021;325(3):311

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Interventions to Promote Tobacco Cessation

Jill Jin, MD, MPH1

doi : 10.1001/jama.2020.25605

JAMA. 2021;325(3):316

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Effect of Tidal Volume on Pulmonary Outcomes After Surgery

Chunmei Zhao, MD1; Yuesong Pan, PhD2; Fang Luo, MD1

doi : 10.1001/jama.2020.22627

JAMA. 2021;325(3):306

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Effect of Tidal Volume on Pulmonary Outcomes After Surgery

Maximilian S. Schaefer, MD1; Daniel Talmor, MD1; Elias N. Baedorf-Kassis, MD2

doi : 10.1001/jama.2020.22633

JAMA. 2021;325(3):306-307

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Effect of Tidal Volume on Pulmonary Outcomes After Surgery

Varun Suresh, MD, DM1

doi : 10.1001/jama.2020.22630

JAMA. 2021;325(3):307

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Effect of Tidal Volume on Pulmonary Outcomes After Surgery—Reply

Dharshi Karalapillai, MD1; Ary Serpa Neto, MD, PhD2; Rinaldo Bellomo, MD3

doi : 10.1001/jama.2020.22636

JAMA. 2021;325(3):307-308

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Physician Performance in the Medicare Merit-based Incentive Payment System

Vinay K. Rathi, MD, MBA1

doi : 10.1001/jama.2020.22800

JAMA. 2021;325(3):308

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Physician Performance in the Medicare Merit-based Incentive Payment System—Reply

Kenton J. Johnston, PhD1; Jason M. Hockenberry, PhD2; Karen E. Joynt Maddox, MD, MPH3,4

doi : 10.1001/jama.2020.22810

JAMA. 2021;325(3):309

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Table Inversion Error

doi : 10.1001/jama.2020.26181

JAMA. 2021;325(3):309

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