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Effect of an Emergency Department Care Bundle on 30-Day Hospital Discharge and Survival Among Elderly Patients With Acute Heart Failure
Yonathan Freund, MD, PhD1,2; Marine Cachanado, MSc3; Quentin Delannoy, MD2; Said Laribi, MD, PhD4; Youri Yordanov, MD, PhD1,5; Judith Gorlicki, MD6; Tahar Chouihed, MD, PhD7; Anne-Laure Féral-Pierssens, PhD8; Jennifer Truchot, MD, PhD9; Thibaut Desmettre, MD, PhD10; Celine Occelli, MD11; Xavier Bobbia, MD, PhD12; Mehdi Khellaf, MD, PhD13; Olivier Ganansia, MD14; Jérôme Bokobza, MD15; Frédéric Balen, MD16; Sebastien Beaune, MD, PhD17; Ben Bloom, MD, PhD18; Tabassome Simon, MD, PhD1,3; Alexandre Mebazaa, MD, PhD19,20,21
doi : 10.1001/jama.2020.19378
JAMA. 2020;324(19):1948-1956
Clinical guidelines for the early management of acute heart failure in the emergency department (ED) setting are based on only moderate levels of evidence, with subsequent low adherence to these guidelines.
Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma
Saud H. AlDubayan, MD1,2,3,4; Jake R. Conway, BSc1,2,5; Sabrina Y. Camp, BSc1,2; Leora Witkowski, PhD6; Eric Kofman, BSc1,2; Brendan Reardon, BSc1,2; Seunghun Han, BA1,2,7; Nicholas Moore, MD1,2; Haitham Elmarakeby, PhD1,2,8; Keyan Salari, MD, PhD9; Hani Choudhry, PhD10; Abdullah M. Al-Rubaish, MD11; Abdulsalam A. Al-Sulaiman, MD11; Amein K. Al-Ali, PhD11; Amaro Taylor-Weiner, PhD2,5; Eliezer M. Van Allen, MD1,2
doi : 10.1001/jama.2020.20457
JAMA. 2020;324(19):1957-1969
Less than 10% of patients with cancer have detectable pathogenic germline alterations, which may be partially due to incomplete pathogenic variant detection.
Association of Childhood Lead Exposure With MRI Measurements of Structural Brain Integrity in Midlife
Aaron Reuben, MEM1; Maxwell L. Elliott, MA1; Wickliffe C. Abraham, PhD2; Jonathan Broadbent, PhD3; Renate M. Houts, PhD1; David Ireland, PhD4; Annchen R. Knodt, MS1; Richie Poulton, PhD4; Sandhya Ramrakha, PhD4; Ahmad R. Hariri, PhD1; Avshalom Caspi, PhD1,5,6,7,8; Terrie E. Moffitt, PhD1,5,6,7,8
doi : 10.1001/jama.2020.19998
JAMA. 2020;324(19):1970-1979
Childhood lead exposure has been linked to disrupted brain development, but long-term consequences for structural brain integrity are unknown.
Financial Penalties Imposed on Large Pharmaceutical Firms for Illegal Activities
Denis G. Arnold, PhD1; Oscar Jerome Stewart, PhD2; Tammy Beck, PhD3
doi : 10.1001/jama.2020.18740
JAMA. 2020;324(19):1995-1997
Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions
Andrea M. Lerner, MD, MS1; Gregory K. Folkers, MS, MPH1; Anthony S. Fauci, MD1
doi : 10.1001/jama.2020.21946
JAMA. 2020;324(19):1935-1936
Postapproval Vaccine Safety Surveillance for COVID-19 Vaccines in the US
Grace M. Lee, MD, MPH1; José R. Romero, MD2,3; Beth P. Bell, MD, MPH4
doi : 10.1001/jama.2020.19692
JAMA. 2020;324(19):1937-1938
Postlicensure Evaluation of COVID-19 Vaccines
Manish M. Patel, MD1; Michael L. Jackson, PhD2; Jill Ferdinands, PhD1
doi : 10.1001/jama.2020.19328
JAMA. 2020;324(19):1939-1940
Heritable Human Genome Editing
Eli Y. Adashi, MD, MS1; I. Glenn Cohen, JD2
doi : 10.1001/jama.2020.19059
JAMA. 2020;324(19):1941-1942
Shear Forces
Stephanie Parks Taylor, MD, MS1
doi : 10.1001/jama.2020.21746
JAMA. 2020;324(19):1943-1944
Bioinformatics, Sequencing Accuracy, and the Credibility of Clinical Genomics
W. Gregory Feero, MD, PhD1,2,3
doi : 10.1001/jama.2020.19939
JAMA. 2020;324(19):1945-1947
Bladder Cancer
Andrew T. Lenis, MD, MS1; Patrick M. Lec, MD1; Karim Chamie; MD, MSHS1
doi : 10.1001/jama.2020.17598
JAMA. 2020;324(19):1980-1991
Bladder cancer is a common malignancy in women and is the fourth most common malignancy in men. Bladder cancer ranges from unaggressive and usually noninvasive tumors that recur and commit patients to long-term invasive surveillance, to aggressive and invasive tumors with high disease-specific mortality.
Dyschromic Nails, Exertional Dyspnea, and Lower Extremity Edema
Soumya Chatterjee, MD, MS1,2; Elliott Chandler Dasenbrook, MD, MHS1,3,4
doi : 10.1001/jama.2020.14648
JAMA. 2020;324(19):1992-1993
Nursing Homes’ Next Test—Vaccinating Workers Against COVID-19
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2020.21354
JAMA. 2020;324(19):1928-1930
Breast Implant Manufacturers Get Labeling Guidance
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2020.22066
JAMA. 2020;324(19):1934
FDA Expands Food Safety Collaboration With Mexico
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2020.21458
JAMA. 2020;324(19):1934
Warning Concerns Respirator Decontamination System
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2020.22068
JAMA. 2020;324(19):1934
To Truly Build the Affordable Care Act Into Universal Coverage, More Creativity Is Needed
Paul Shafer, PhD1; Austin B. Frakt, PhD1,2
doi : 10.1001/jama.2020.21609
JAMA. 2020;324(19):1931-1932
Dried Blood Spots May Offer Route to Wider Antibody Testing
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2020.21109
JAMA. 2020;324(19):1933
Partnership to Make 120 Million COVID-19 Rapid Tests Available
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2020.22082
JAMA. 2020;324(19):1933
Global Mental Health Services Are Collapsing as Demand Grows
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2020.22085
JAMA. 2020;324(19):1933
Bladder Cancer
Andrew T. Lenis, MD, MS1; Patrick M. Lec, MD1; Karim Chamie, MD, MSHS1
doi : 10.1001/jama.2020.17601
JAMA. 2020;324(19):2006
Assessing Alternative Payment Models
Suhas Gondi, BA1; Rishi K. Wadhera, MD, MPP, MPhil2
doi : 10.1001/jama.2020.19006
JAMA. 2020;324(19):1997-1998
Assessing Alternative Payment Models—Reply
Amol S. Navathe, MD, PhD1; Connor W. Boyle, BA1; Ezekiel J. Emanuel, MD, PhD1
doi : 10.1001/jama.2020.19021
JAMA. 2020;324(19):1998
Testing Clinical Prediction Models
Benjamin A. Goldstein, PhD1; Michael J. Pencina, PhD1
doi : 10.1001/jama.2020.19392
JAMA. 2020;324(19):1998-1999
Testing Clinical Prediction Models
Junfeng Wang, PhD1; Yue Li, MSc2
doi : 10.1001/jama.2020.19389
JAMA. 2020;324(19):1999-2000
Testing Clinical Prediction Models—Reply
Amin Adibi, MSc1; Mohsen Sadatsafavi, MD, PhD1; John P. A. Ioannidis, MD, DSc2
doi : 10.1001/jama.2020.19413
JAMA. 2020;324(19):2000
