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doi : 10.1038/s41587-023-02005-1

Volume 41 Issue 10, October 2023

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Scientists hone tools to measure aging and rejuvenation interventions

Lisa Melton

doi : 10.1038/d41587-023-00008-6

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New guise ADCs couple antibodies to degraders

doi : 10.1038/s41587-023-02001-5

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From air to your plate: tech startups making food from atmospheric CO2

Claire Turrell 

doi : 10.1038/s41587-023-01992-5

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Pharma deal making: a bright spot amid the gloom

Melanie Senior 

doi : 10.1038/s41587-023-01958-7

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The long game of tenure

Todd J. Treangen & Moshe Y. VardiÂ

doi : 10.1038/s41587-023-01929-y

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Tenure time loopers

Nozomu Yachie & Nika ShakibaÂ

doi : 10.1038/s41587-023-01924-3

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A new chance for genome editing in Europe

Hervé Vanderschuren, Patience Chatukuta, Detlef Weigel & Devang MehtaÂ

doi : 10.1038/s41587-023-01969-4

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Are ecological processes that select beneficial traits in agricultural microbes nature’s intellectual property rights?

David Kothamasi, Saskia Vermeylen & Sharma DeepikaÂ

doi : 10.1038/s41587-023-01966-7

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Implantable biosensor tracks temperature to detect early transplant rejection in rats

Anahita Bishop 

doi : 10.1038/s41587-023-01998-z

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Advancing missense variant pathogenicity prediction

Rong Li 

doi : 10.1038/s41587-023-01999-y

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Monitoring protein proximity with fluorogens

Alexandra Despang 

doi : 10.1038/s41587-023-02000-6

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CRISPR editing in the lung with novel lipids

Uri Elia, Edo Kon & Dan PeerÂ

doi : 10.1038/s41587-023-01744-5

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Human microbiome cultivation expands with AI

Marta Selma-Royo, Nicola Segata & Liviana RicciÂ

doi : 10.1038/s41587-023-01852-2

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Speed reading the epigenome and genome

James M. George & Arul M. ChinnaiyanÂ

doi : 10.1038/s41587-023-01757-0

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Lipid nanoparticle-enabled gene editing in the lung via inhalation

doi : 10.1038/s41587-023-01689-9

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Computational framework decomposes and annotates single-cell and spatial omics

doi : 10.1038/s41587-023-01658-2

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Interstrand crosslinking of homologous repair template DNA enhances gene editing in human cells

Hannah I. Ghasemi, Julien Bacal, Amanda C. Yoon, Katherine U. Tavasoli, Carmen Cruz, Jonathan T. Vu, Brooke M. Gardner & Chris D. RichardsonÂ

doi : 10.1038/s41587-022-01654-y

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High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq

Yang Liu, Marcello DiStasio, Graham Su, Hiromitsu Asashima, Archibald Enninful, Xiaoyu Qin, Yanxiang Deng, Jungmin Nam, Fu Gao, Pino Bordignon, Marco Cassano, Mary Tomayko, Mina Xu, Stephanie Halene, Joseph E. Craft, David Hafler & Rong FanÂ

doi : 10.1038/s41587-023-01676-0

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Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing

Bowen Li, Rajith Singh Manan, Shun-Qing Liang, Akiva Gordon, Allen Jiang, Andrew Varley, Guangping Gao, Robert Langer, Wen Xue & Daniel AndersonÂ

doi : 10.1038/s41587-023-01679-x

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gutSMASH predicts specialized primary metabolic pathways from the human gut microbiota

Victòria Pascal Andreu, Hannah E. Augustijn, Lianmin Chen, Alexandra Zhernakova, Jingyuan Fu, Michael A. Fischbach, Dylan Dodd & Marnix H. MedemaÂ

doi : 10.1038/s41587-023-01675-1

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High-throughput microbial culturomics using automation and machine learning

Yiming Huang, Ravi U. Sheth, Shijie Zhao, Lucas A. Cohen, Kendall Dabaghi, Thomas Moody, Yiwei Sun, Deirdre Ricaurte, Miles Richardson, Florencia Velez-Cortes, Tomasz Blazejewski, Andrew Kaufman, Carlotta Ronda & Harris H. WangÂ

doi : 10.1038/s41587-023-01674-2

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Synapse-tuned CARs enhance immune cell anti-tumor activity

Peter J. Chockley, Jorge Ibanez-Vega, Giedre Krenciute, Lindsay J. Talbot & Stephen GottschalkÂ

doi : 10.1038/s41587-022-01650-2

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Prediction of prime editing insertion efficiencies using sequence features and DNA repair determinants

Jonas Koeppel, Juliane Weller, Elin Madli Peets, Ananth Pallaseni, Ivan Kuzmin, Uku Raudvere, Hedi Peterson, Fabio Giuseppe Liberante & Leopold PartsÂ

doi : 10.1038/s41587-023-01678-y

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Simultaneous sequencing of genetic and epigenetic bases in DNA

Jens Füllgrabe, Walraj S. Gosal, Páidí Creed, Sidong Liu, Casper K. Lumby, David J. Morley, Tobias W. B. Ost, Albert J. Vilella, Shirong Yu, Helen Bignell, Philippa Burns, Tom Charlesworth, Beiyuan Fu, Howerd Fordham, Nicolas J. Harding, Olga Gandelman, Paula Golder, Christopher Hodson, Mengjie Li, Marjana Lila, Yang Liu, Joanne Mason, Jason Mellad, Jack M. Monahan, …Shankar BalasubramanianÂ

doi : 10.1038/s41587-022-01652-0

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TACCO unifies annotation transfer and decomposition of cell identities for single-cell and spatial omics

Simon Mages, Noa Moriel, Inbal Avraham-Davidi, Evan Murray, Jan Watter, Fei Chen, Orit Rozenblatt-Rosen, Johanna Klughammer, Aviv Regev & Mor NitzanÂ

doi : 10.1038/s41587-023-01657-3

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Telomere-to-telomere assembly of diploid chromosomes with Verkko

Mikko Rautiainen, Sergey Nurk, Brian P. Walenz, Glennis A. Logsdon, David Porubsky, Arang Rhie, Evan E. Eichler, Adam M. Phillippy & Sergey KorenÂ

doi : 10.1038/s41587-023-01662-6

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Author Correction: Unidirectional single-file transport of full-length proteins through a nanopore

Luning Yu, Xinqi Kang, Fanjun Li, Behzad Mehrafrooz, Amr Makhamreh, Ali Fallahi, Joshua C. Foster, Aleksei Aksimentiev, Min Chen & Meni WanunuÂ

doi : 10.1038/s41587-023-01995-2

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A strategy to incentivize innovation in the health care system: the innovation RVU

Nathan V. Mallipeddi, Jay Chandra & Marc D. SucciÂ

doi : 10.1038/s41587-023-01971-w

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