American Journal of Clinical Nutrition




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Grading nutrition evidence: where to go from here? 

Deirdre K Tobias, Clemens Wittenbecher, Frank B Hu

doi : 10.1093/ajcn/nqab124

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1385–1387

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Can an apple a day keep cancer away?

Chen Yuan, Kimmie Ng

doi : 10.1093/ajcn/nqab133

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1388–1389

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Anemia in pregnant women with HIV: Insights and implications about iron for all pregnant women and infants

Sarah Detlefs, Jacquelyn M Powers

doi : 10.1093/ajcn/nqab056

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1390–1391

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Neuroplasticity and the role of exercise and diet on cognition

Nicolaas P Pronk

doi : 10.1093/ajcn/nqab083

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1392–1393

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Low FODMAP (fermentable oligo-, di-, monosaccharides, and polyol) diet goes global

Eamonn M M Quigley

doi : 10.1093/ajcn/nqab084

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1394–1395

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Pushing the boundaries of precision nutrition to tackle Alzheimer's disease: is there a role for DHA?

Luisa Fernandez-Chirino, Neftali Eduardo Antonio-Villa, Omar Yaxmehen Bello-Chavolla

doi : 10.1093/ajcn/nqab085

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1396–1397

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Measuring calf circumference: a practical tool to predict skeletal muscle mass via adjustment with BMI

Gülistan Bahat

doi : 10.1093/ajcn/nqab107

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1398–1399

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Trimethylamine N-oxide variation in humans: the product of a diet–microbiota interaction?

Curtis Tilves, Noel T Mueller

doi : 10.1093/ajcn/nqab108

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1400–1401

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Maternal anemia and preterm birth among women living with HIV in the United States

Denise L Jacobson, Daniela Neri, Audrey Gaskins, Lynn Yee, Armando J Mendez, Kristy Hendricks, Suzanne Siminski, Rebecca Zash, Laurie Hyzy, Jennifer Jao, Pediatric HIV/AIDS Cohort Study

doi : 10.1093/ajcn/nqaa441

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1402–1410

Women living with HIV (WLHIV) have a higher prevalence of anemia than women without HIV, possibly related to the effects of HIV and antiretroviral medications.

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Does supplementation with leucine-enriched protein alone and in combination with fish-oil-derived n–3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? A randomized, double-blind, placebo-controlled trial 

Caoileann H Murphy, Ellen M Flanagan, Giuseppe De Vito, Davide Susta, Kathleen A J Mitchelson, Elena de Marco Castro, Joan M G Senden, Joy P B Goessens, Agnieszka Mik?osz, Adrian Chabowski, Ricardo Segurado, Clare A Corish, Sinead N McCarthy, Brendan Egan, Luc J C van Loon, Helen M Roche

doi : 10.1093/ajcn/nqaa449

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1411–1427

Leucine-enriched protein (LEU-PRO) and long-chain (LC) n–3 (?–3) PUFAs have each been proposed to improve muscle mass and function in older adults, whereas their combination may be more effective than either alone.

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Exercise, diet, and cognition in a 4-year randomized controlled trial: Dose-Responses to Exercise Training (DR's EXTRA) 

Pirjo Komulainen, Jaakko Tuomilehto, Kai Savonen, Reija M?nnikk?, Maija Hassinen, Timo A Lakka, Tuomo H?nninen, Vesa Kiviniemi, David R Jacobs, Jr, Miia Kivipelto, Rainer Rauramaa

doi : 10.1093/ajcn/nqab018

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1428–1439

Evidence for the effects of exercise and dietary interventions on cognition from long-term randomized controlled trials (RCTs) in large general populations remains insufficient.

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Effect of Schisandra chinensis Baillon extracts and regular low-intensity exercise on muscle strength and mass in older adults: a randomized, double-blind, placebo-controlled trial

Young H Cho, Sang Y Lee, Chang-Hyung Lee, Jong-Hwan Park, Yong S So

doi : 10.1093/ajcn/nqaa447

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1440–1446

Studies suggest that Schisandra chinensis Baillon (Sc) may enhance muscle strength and mass because of its anti-inflammatory and antioxidant properties.

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Lifestyle after colorectal cancer diagnosis in relation to recurrence and all-cause mortality 

Moniek van Zutphen, Hendriek C Boshuizen, Marlou-Floor Kenkhuis, Evertine Wesselink, Anne J M R Geijsen, Johannes H W de Wilt, Henk K van Halteren, Ernst Jan Spillenaar Bilgen, Eric T P Keulen, Maryska L G Janssen-Heijnen, Stéphanie O Breukink, Martijn J L Bours, Dieuwertje E Kok, Renate M Winkels, Matty P Weijenberg, Ellen Kampman, Fr?nzel J B van Duijnhoven

doi : 10.1093/ajcn/nqaa394

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1447–1457

An unhealthy lifestyle is associated with the risk of colorectal cancer (CRC), but it is unclear whether overall lifestyle after a CRC diagnosis is associated with risks of recurrence and mortality.

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The association of vitamin D with survival in colorectal cancer patients depends on antioxidant capacity

Daniel Boakye, Lina Jansen, Ben Sch?ttker, Eugene H J M Jansen, Niels Halama, Haifa Maalmi, Xin Gào, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner

doi : 10.1093/ajcn/nqaa405

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1458–1467

Vitamin D plays a role in detoxifying free radicals, which might explain the previously reported lower mortality in colorectal cancer (CRC) patients with higher vitamin D concentrations.

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Circulating B-vitamin biomarkers and B-vitamin supplement use in relation to quality of life in patients with colorectal cancer: results from the FOCUS consortium

Janna L Koole, Martijn J L Bours, Anne J M R Geijsen, Biljana Gigic, Arve Ulvik, Dieuwertje E Kok, Stefanie Brezina, Jennifer Ose, Andreas Baierl, Jürgen B?hm, Hermann Brenner, Stéphanie O Breukink, Jenny Chang-Claude, Fr?nzel J B van Duijnhoven, Peter van Duijvendijk, Tanja Gumpenberger, Nina Habermann, Henk K van Halteren, Michael Hoffmeister, Andreana N Holowatyj, Maryska L G Janssen-Heijnen, Eric T P Keulen, Rama Kiblawi, Flip M Kruyt, Christopher I Li, Tengda Lin, ?ivind Midttun, Anita R Peoples, Eline H van Roekel, Martin A Schneider, Petra Schrotz-King, Alexis B Ulrich, Kathy Vickers, Evertine Wesselink, Johannes H W de Wilt, Andrea Gsur, Per M Ueland, Cornelia M Ulrich, Ellen Kampman, Matty P Weijenberg

doi : 10.1093/ajcn/nqaa422

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1468–1481

B vitamins have been associated with the risk and progression of colorectal cancer (CRC), given their central roles in nucleotide synthesis and methylation, yet their association with quality of life in established CRC is unclear.

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Weight stability masks changes in body composition in colorectal cancer: a retrospective cohort study

Justin C Brown, Bette J Caan, Elizabeth M Cespedes Feliciano, Jingjie Xiao, Erin Weltzien, Carla M Prado, Candyce H Kroenke, Adrienne Castillo, Marilyn L Kwan, Jeffrey A Meyerhardt

doi : 10.1093/ajcn/nqaa440

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1482–1489

There is an emerging viewpoint that change in body weight is not sufficiently sensitive to promptly identify clinically meaningful change in body composition, such as skeletal muscle depletion.

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Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: a Mendelian randomization study

Konstantinos K Tsilidis, Nikos Papadimitriou, Niki Dimou, Dipender Gill, Sarah J Lewis, Richard M Martin, Neil Murphy, Georgios Markozannes, Verena Zuber, Amanda J Cross, Kimberley Burrows, David S Lopez, Timothy J Key, Ruth C Travis, Aurora Perez-Cornago, David J Hunter, Fr?nzel J B van Duijnhoven, Demetrius Albanes, Volker Arndt, Sonja I Berndt, Stéphane Bézieau, D Timothy Bishop, Juergen Boehm, Hermann Brenner, Andrea Burnett-Hartman, Peter T Campbell, Graham Casey, Sergi Castellv?-Bel, Andrew T Chan, Jenny Chang-Claude, Albert de la Chapelle, Jane C Figueiredo, Steven J Gallinger, Graham G Giles, Phyllis J Goodman, Andrea Gsur, Jochen Hampe, Heather Hampel, Michael Hoffmeister, Mark A Jenkins, Temitope O Keku, Sun-Seog Kweon, Susanna C Larsson, Loic Le Marchand, Christopher I Li, Li Li, Annika Lindblom, Vicente Mart?n, Roger L Milne, Victor Moreno, Hongmei Nan, Rami Nassir, Polly A Newcomb, Kenneth Offit, Paul D P Pharoah, Elizabeth A Platz, John D Potter, Lihong Qi, Gad Rennert, Lori C Sakoda, Clemens Shafmayer, Martha L Slattery, Linda Snetselaar, Jeanette Schenk, Stephen N Thibodeau, Cornelia M Ulrich, Bethany Van Guelpen, Sophia Harlid, Kala Visvanathan, Ludmila Vodickova, Hansong Wang, Emily White, Alicja Wolk, Michael O Woods, Anna H Wu, Wei Zheng, Bas Bueno-de-Mesquita, Marie-Christine Boutron-Ruault, David J Hughes, Paula Jakszyn, Tilman Kühn, Domenico Palli, Elio Riboli, Edward L Giovannucci, Barbara L Banbury, Stephen B Gruber, Ulrike Peters, Marc J Gunter on behalf of GECCO, CORECT, and CCFR

doi : 10.1093/ajcn/nqab003

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1490–1502

The literature on associations of circulating concentrations of minerals and vitamins with risk of colorectal cancer is limited and inconsistent. Evidence from randomized controlled trials (RCTs) to support the efficacy of dietary modification or nutrient supplementation for colorectal cancer prevention is also limited.

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Dietary factors, gut microbiota, and serum trimethylamine-N-oxide associated with cardiovascular disease in the Hispanic Community Health Study/Study of Latinos 

Zhendong Mei, Guo-Chong Chen, Zheng Wang, Mykhaylo Usyk, Bing Yu, Yoshiki Vazquez Baeza, Greg Humphrey, Rodolfo Salido Benitez, Jun Li, Jessica S Williams-Nguyen, Martha L Daviglus, Lifang Hou, Jianwen Cai, Yan Zheng, Rob Knight, Robert D Burk, Eric Boerwinkle, Robert C Kaplan, Qibin Qi

doi : 10.1093/ajcn/nqab001

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1503–1514

Trimethylamine-N-oxide (TMAO), a diet-derived and gut microbiota–related metabolite, is associated with cardiovascular disease (CVD). However, major dietary determinants and specific gut bacterial taxa related to TMAO remain to be identified in humans.

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Higher intake of microbiota-accessible carbohydrates and improved cardiometabolic risk factors: a meta-analysis and umbrella review of dietary management in patients with type 2 diabetes

Bocheng Xu, Jie Fu, Yanxiang Qiao, Jinping Cao, Edward C Deehan, Zhi Li, Mingliang Jin, Xinxia Wang, Yizhen Wang

doi : 10.1093/ajcn/nqaa435

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1515–1530

Microbiota-accessible carbohydrates (MACs) are critical substrates for intestinal microbes; the subsequent production of SCFAs may have some potential benefits for patients with type 2 diabetes mellitus (T2DM).

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Low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols diet compared with traditional dietary advice for diarrhea-predominant irritable bowel syndrome: a parallel-group, randomized controlled trial with analysis of clinical and microbiological factors associated with patient outcomes

Yawen Zhang, Lijun Feng, Xin Wang, Mark Fox, Liang Luo, Lijun Du, Binrui Chen, Xiaoli Chen, Huiqin He, Shuwen Zhu, Zhefang Hu, Shujie Chen, Yanqin Long, Yubin Zhu, Li Xu, Yanyong Deng, Benjamin Misselwitz, Brian M Lang, Bahtiyar Yilmaz, John J Kim, Chung Owyang, Ning Dai

doi : 10.1093/ajcn/nqab005

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1531–1545

The efficacy and factors associated with patient outcomes for a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (LFD) compared with traditional dietary advice (TDA) based on modified National Institute for Clinical Excellence guidelines for irritable bowel syndrome with diarrhea (IBS-D) in regions consuming a non-Western diet are unclear.

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Nutrition and origin of US chain restaurant seafood 

David C Love, Catherine Turvey, Jamie Harding, Ruth Young, Rebecca Ramsing, Michael F Tlusty, Jillian P Fry, Ly Nguyen, Frank Asche, Elizabeth M Nussbaumer, Andrew L Thorne-Lyman, Martin Bloem

doi : 10.1093/ajcn/nqaa437

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1546–1555

Seafood has a nutritional profile that can be beneficial to human health, which gives it a role to play in healthy diets. In addition, because its production and harvesting can have fewer environmental impacts than some forms of animal protein, it can contribute to sustainable diets. However, the positive health and environmental outcomes are not guaranteed—they depend on how seafood is prepared and served and whether it is sourced from sustainable fisheries and aquaculture industries.

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Biomarkers of environmental enteric dysfunction are differently associated with recovery and growth among children with moderate acute malnutrition in Sierra Leone 

Akriti Singh, Shibani Ghosh, Honorine Ward, Mark J Manary, Beatrice L Rogers, Irwin H Rosenberg

doi : 10.1093/ajcn/nqaa434

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1556–1564

Environmental enteric dysfunction (EED) may influence growth during and recovery from moderate acute malnutrition (MAM), however, biomarkers to assess these relations have yet to be identified.

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Growth, body composition, and cardiovascular and nutritional risk of 5- to 10-y-old children consuming vegetarian, vegan, or omnivore diets 

Ma?gorzata A Desmond, Jakub G Sobiecki, Maciej Jaworski, Pawe? P?udowski, Jolanta Antoniewicz, Meghan K Shirley, Simon Eaton, Janusz Ksi??yk, Mario Cortina-Borja, Bianca De Stavola, Mary Fewtrell, Jonathan C K Wells

doi : 10.1093/ajcn/nqaa445

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1565–1577

Plant-based diets (PBDs) are increasingly recommended for human and planetary health. However, comprehensive evidence on the health effects of PBDs in children remains incomplete, particularly in vegans.

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Characteristics and quality of systematic reviews and meta-analyses of observational nutritional epidemiology: a cross-sectional study 

Dena Zeraatkar, Arrti Bhasin, Rita E Morassut, Isabella Churchill, Arnav Gupta, Daeria O Lawson, Anna Miroshnychenko, Emily Sirotich, Komal Aryal, David Mikhail, Tauseef A Khan, Vanessa Ha, John L Sievenpiper, Steven E Hanna, Joseph Beyene, Russell J de Souza

doi : 10.1093/ajcn/nqab002

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1578–1592

Dietary recommendations and policies should be guided by rigorous systematic reviews. Reviews that are of poor methodological quality may be ineffective or misleading. Most of the evidence in nutrition comes from nonrandomized studies of nutritional exposures (usually referred to as nutritional epidemiology studies), but to date methodological evaluations of the quality of systematic reviews of such studies have been sparse and inconsistent.

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Effects of dietary macronutrients on serum urate: results from the OmniHeart trial

Matthew J Belanger, Christina C Wee, Kenneth J Mukamal, Edgar R Miller, III, Frank M Sacks, Lawrence J Appel, Robert H Shmerling, Hyon K Choi, Stephen P Juraschek

doi : 10.1093/ajcn/nqaa424

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1593–1599

Dietary recommendations to prevent gout emphasize a low-purine diet. Recent evidence suggests that the Dietary Approaches to Stop Hypertension (DASH) diet reduces serum urate while also improving blood pressure and lipids.

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Prior undernutrition and insulin production several years later in Tanzanian adults 

Suzanne Filteau, George PrayGod, Andrea M Rehman, Robert Peck, Kidola Jeremiah, Rikke Krogh-Madsen, Daniel Faurholt-Jepsen

doi : 10.1093/ajcn/nqaa438

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1600–1608

The prevalence, pathology, and existence of malnutrition-associated diabetes remain uncertain, especially with respect to adult-acquired undernutrition.

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Breastfeeding and wheeze-related outcomes in high-risk infants: A systematic review and meta-analysis

Soriah M Harvey, Vanessa E Murphy, Olivia M Whalen, Peter G Gibson, Megan E Jensen

doi : 10.1093/ajcn/nqaa442

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1609–1618

The risk of wheezing is high in infancy and is heightened in infants with a family history of asthma/atopy. The role of breastfeeding in influencing respiratory health for these high-risk infants is unclear.

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Healthy dietary patterns are associated with lower concentrations of growth differentiation factor 15 in older adults

Rosario Ortol?, Esther Garc?a-Esquinas, Antonio Bu?o-Soto, Mercedes Sotos-Prieto, Ellen A Struijk, Francisco Félix Caballero, Esther Lopez-Garcia, José R Banegas, Fernando Rodr?guez-Artalejo

doi : 10.1093/ajcn/nqaa444

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1619–1626

Growth differentiation factor 15 (GDF-15) is a biomarker for aging and chronic disease burden that may capture the anti-inflammatory and antioxidant effects attributed to healthy diets.

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DHA intake relates to better cerebrovascular and neurodegeneration neuroimaging phenotypes in middle-aged adults at increased genetic risk of Alzheimer disease 

Aleix Sala-Vila, Eider M Arenaza-Urquijo, Gonzalo S?nchez-Benavides, Marc Su?rez-Calvet, Marta Milà-Alomà, Oriol Grau-Rivera, José M Gonz?lez-de-Ech?varri, Marta Crous-Bou, Carolina Minguill?n, Karine Fauria, Grégory Operto, Carles Falc?n, Gemma Salvad?, Raffaele Cacciaglia, Silvia Ingala, Frederik Barkhof, Helmut Schr?der, Nikolaos Scarmeas, Juan-Domingo Gispert, José L Molinuevo, for the ALFA study

doi : 10.1093/ajcn/nqab016

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1627–1635

The number of APOE-?4 alleles is a major nonmodifiable risk factor for sporadic Alzheimer disease (AD). There is increasing evidence on the benefits of dietary DHA (22:6n–3) before the onset of AD symptoms, particularly in APOE-?4 carriers. Brain alterations in the preclinical stage can be detected by structural MRI.

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Postdiagnostic dairy products intake and colorectal cancer survival in US males and females

Xing Liu, Wanshui Yang, Kana Wu, Shuji Ogino, Weibing Wang, Na He, Andrew T Chan, Zuo-Feng Zhang, Jeffrey A Meyerhardt, Edward Giovannucci, Xuehong Zhang

doi : 10.1093/ajcn/nqab059

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1636–1646

To evaluate the association between postdiagnostic dairy intake and survival among patients with colorectal cancer (CRC).

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Novel equation for estimating resting energy expenditure in patients with chronic kidney disease

Xiao Xu, Zhikai Yang, Tiantian Ma, Ziqian Li, Yuan Chen, Yingdong Zheng, Jie Dong

doi : 10.1093/ajcn/nqaa431

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1647–1656

In chronic kidney disease (CKD), determining energy expenditure is the precondition for recommending energy intake in nutrition management.

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Direct assessment of body iron balance in women with and without iron supplementation using a long-term isotope dilution method in Benin and Switzerland

Cornelia Speich, Comlan Evariste S Mitchikpè, Colin I Cercamondi, Christophe Zeder, Gary M Brittenham, Diego Moretti, Michael B Zimmermann

doi : 10.1093/ajcn/nqaa433

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1657–1669

Long-term isotopic dilution measurements of body iron may allow quantification of basal body iron balance and iron gains during an iron intervention with higher precision and accuracy than conventional iron indices.

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Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver

David A Horita, Sunil Hwang, Julie M Stegall, Walter B Friday, David R Kirchner, Steven H Zeisel

doi : 10.1093/ajcn/nqaa439

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1670–1678

Choline deficiency has numerous negative health consequences; although the preponderance of the US population consumes less than the recommended Adequate Intake (AI), clinical assessment of choline status is difficult. Further, several pathways involved in primary metabolism of choline are estrogen-sensitive and the AI for premenopausal women is lower than that for men.

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Calf circumference: cutoff values from the NHANES 1999–2006

Maria Cristina Gonzalez, Ali Mehrnezhad, Nariman Razaviarab, Thiago G Barbosa-Silva, Steven B Heymsfield

doi : 10.1093/ajcn/nqab029

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1679–1687

Calf circumference (CC) is used in geriatric studies as a simple and practical skeletal muscle (SM) marker for diagnosing low SM and sarcopenia. Currently applied CC cutoff points were developed in samples including older participants; values representative of the full adult lifespan are lacking.

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Short interpregnancy intervals and risks for birth defects: support for the nutritional depletion hypothesis

Julie M Petersen, Mahsa M Yazdy, Kelly D Getz, Marlene T Anderka, Martha M Werler, National Birth Defects Prevention Study

doi : 10.1093/ajcn/nqaa436

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1688–1699

Research suggests short interpregnancy intervals increase risks for adverse perinatal outcomes, including some birth defects. A hypothesized cause is nutritional depletion, including folic acid (FA).

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Effects of menopausal hormone therapy on erythrocyte n–3 and n–6 PUFA concentrations in the Women's Health Initiative randomized trial

William S Harris, Nathan L Tintle, JoAnn E Manson, Adam H Metherel, Jennifer G Robinson

doi : 10.1093/ajcn/nqaa443

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1700–1706

The factors other than dietary intake that determine tissue concentrations of EPA and DHA remain obscure. Prior studies suggested that, in women, endogenous estrogen may accelerate synthesis of DHA from ?-linolenic acid (ALA), but the effects of exogenous estrogen on RBC n–3 (?-3) PUFA concentrations are unknown.

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Recommendations to adjust national vitamin A intervention policy must follow a consistent framework

Jesse Sheftel, Devika J Suri, Sherry A Tanumihardjo

doi : 10.1093/ajcn/nqab104

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1707–1708

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Sample size covered for serum vitamin A is not nationally representative: data are not suggestive for Targeted Vitamin A Supplementation Programme in India

Nimmathota Arlappa

doi : 10.1093/ajcn/nqab105

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1708–1709

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Reply to J Sheftel et al. and N Arlappa

G Bhanuprakash Reddy, Raghu Pullakhandam, Santu Ghosh, Naveen Boiroju, Shalini Tattari, Avula Laxmaiah, Rajkumar Hemalatha, Umesh Kapil, Harshpal S Sachdev, Anura V Kurpad

doi : 10.1093/ajcn/nqab106

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1709–1711

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The homeoviscous adaptation to dietary lipids (HADL) hypothesis is probably incorrect 

Jacob J Christensen, Vibeke H Telle-Hansen, Stine M Ulven, Petri T Kovanen, Matti Jauhiainen, Katariina ??rni, Kirsten B Holven

doi : 10.1093/ajcn/nqab110

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1711–1712

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Reply to JJ Christensen et al. 

Marit K Zin?cker, Karianne Svendsen, Kandice R Levental, Ilya Levental, Simon N Dankel

doi : 10.1093/ajcn/nqab111

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1712–1713

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Measuring the abdomen's height rather than its circumference

Henry S Kahn

doi : 10.1093/ajcn/nqab141

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1713–1714

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Corrigendum to “Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: a Mendelian randomization study. Am J Clin Nutr 2021.

doi : 10.1093/ajcn/nqab003

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Page 1715

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Erratum to: Milky Ways: Effects of Maternal Obesity on Human Milk Composition and Childhood Obesity Risk. Am J Clin Nutr 2021;113(4):772–74. 

doi : 10.1093/ajcn/nqab155

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Page 1715

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Calendar of Events

doi : 10.1093/ajcn/nqab190

The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Page 1716

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