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When are your cells no longer your own?

doi : 10.1038/s41587-023-01968-5

Volume 41 Issue 9, September 2023

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Hair loss treatments take aim at the immune system

Charlotte Harrison 

doi : 10.1038/s41587-023-01939-w

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FDA approves first-in-class bispecific for multiple myeloma

doi : 10.1038/s41587-023-01962-x

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Drugs catch a ride through the blood–brain barrier

Cormac Sheridan 

doi : 10.1038/s41587-023-01936-z

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Public biotech in 2022 � the numbers

Laura DeFrancesco & Riku LähteenmäkiÂ

doi : 10.1038/s41587-023-01923-4

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Plant cell-based drug delivery enhances affordability of biologics

Henry Daniell, Rachel J. Kulchar, Roland W. Herzog, Mike Kulis & Kam W. LeongÂ

doi : 10.1038/s41587-023-01899-1

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Advancing artificial intelligence to help feed the world

Ben J. Hayes, Chensong Chen, Owen Powell, Eric Dinglasan, Kira Villiers, Kathryn E. Kemper & Lee T. HickeyÂ

doi : 10.1038/s41587-023-01898-2

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A way forward for diagnosis of patients with extremely rare genetic mutations

Stanley T. Crooke, Olivia S. Kim-McManus & Kelley DalbyÂ

doi : 10.1038/s41587-023-01879-5

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The global patent landscape of mRNA for diagnosis and therapy

Mengru Lyu, Jiyuan Chen, Yeheng Peng, Fang Han, Luyao Gong, Jingfei Guo, Lijuan Tian & Yuan GaoÂ

doi : 10.1038/s41587-023-01925-2

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Mining extinct proteomes for antimicrobial peptides

Barbara CheifetÂ

doi : 10.1038/s41587-023-01959-6

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A biosensor detects tumor DNA in vivo

Anne Doerr 

doi : 10.1038/s41587-023-01960-z

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Targeting hematopoietic stem cells in vivo

Kathryn AschheimÂ

doi : 10.1038/s41587-023-01961-y

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CLASH enables large-scale parallel knock-in for cell engineering

doi : 10.1038/s41587-023-01664-4

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CRISPR-Csm for eukaryotic RNA knockdown and imaging without toxicity

doi : 10.1038/s41587-023-01665-3

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Spatial tropism profiling of AAV vectors by ultrasensitive sequential FISH in tissue

doi : 10.1038/s41587-023-01681-3

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Wearable sensors for monitoring marine environments and their inhabitants

Altynay Kaidarova, Nathan R. Geraldi, Rory P. Wilson, Jürgen Kosel, Mark G. Meekan, Víctor M. Eguíluz, Muhammad Mustafa Hussain, Atif Shamim, Hanguang Liao, Mani Srivastava, Swapnil Sayan Saha, Michael S. Strano, Xiangliang Zhang, Boon S. Ooi, Mark Holton, Lloyd W. Hopkins, Xiaojia Jin, Xun Gong, Flavio Quintana, Adylkhan Tovasarov, Assel Tasmagambetova & Carlos M. DuarteÂ

doi : 10.1038/s41587-023-01827-3

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Methodological concerns and lack of evidence for single-synapse RNA-seq

Benjamin D. Hobson & Etienne HerzogÂ

doi : 10.1038/s41587-023-01877-7

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Reply to: Methodological concerns and lack of evidence for single-synapse RNA-seq

Muchun Niu & Chenghang ZongÂ

doi : 10.1038/s41587-023-01878-6

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Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells

Sangwook Oh, Xuming Mao, Silvio Manfredo-Vieira, Jinmin Lee, Darshil Patel, Eun Jung Choi, Andrea Alvarado, Ebony Cottman-Thomas, Damian Maseda, Patricia Y. Tsao, Christoph T. Ellebrecht, Sami L. Khella, David P. Richman, Kevin C. O’Connor, Uri Herzberg, Gwendolyn K. Binder, Michael C. Milone, Samik Basu & Aimee S. PayneÂ

doi : 10.1038/s41587-022-01637-z

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Precise transcript targeting by CRISPR-Csm complexes

David Colognori, Marena Trinidad & Jennifer A. DoudnaÂ

doi : 10.1038/s41587-022-01649-9

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Massively parallel knock-in engineering of human T cells

Xiaoyun Dai, Jonathan J. Park, Yaying Du, Zhenkun Na, Stanley Z. Lam, Ryan D. Chow, Paul A. Renauer, Jianlei Gu, Shan Xin, Zhiyuan Chu, Cun Liao, Paul Clark, Hongyu Zhao, Sarah Slavoff & Sidi ChenÂ

doi : 10.1038/s41587-022-01639-x

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Chem-map profiles drug binding to chromatin in cells

Zutao Yu, Jochen Spiegel, Larry Melidis, Winnie W. I. Hui, Xiaoyun Zhang, Antanas RadzeviÄ�ius & Shankar BalasubramanianÂ

doi : 10.1038/s41587-022-01636-0

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Spatial transcriptomics for profiling the tropism of viral vectors in tissues

Min J. Jang, Gerard M. Coughlin, Cameron R. Jackson, Xinhong Chen, Miguel R. Chuapoco, Julia L. Vendemiatti, Alexander Z. Wang & Viviana GradinaruÂ

doi : 10.1038/s41587-022-01648-w

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Tension-tuned receptors for synthetic mechanotransduction and intercellular force detection

D. Christopher Sloas, Jeremy C. Tran, Alexander M. Marzilli & John T. NgoÂ

doi : 10.1038/s41587-022-01638-y

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Control of acute myeloid leukemia by a trifunctional NKp46-CD16a-NK cell engager targeting CD123

Laurent Gauthier, Angela Virone-Oddos, Jochen Beninga, Benjamin Rossi, Céline Nicolazzi, Céline Amara, Audrey Blanchard-Alvarez, Nicolas Gourdin, Jacqueline Courta, Alexandra Basset, Magali Agnel, Franceline Guillot, Gwendoline Grondin, Hélène Bonnevaux, Anne-Laure Bauchet, Ariane Morel, Yannis Morel, Marielle Chiron & Eric VivierÂ

doi : 10.1038/s41587-022-01626-2

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Three-dimensional structured illumination microscopy with enhanced axial resolution

Xuesong Li, Yicong Wu, Yijun Su, Ivan Rey-Suarez, Claudia Matthaeus, Taylor B. Updegrove, Zhuang Wei, Lixia Zhang, Hideki Sasaki, Yue Li, Min Guo, John P. Giannini, Harshad D. Vishwasrao, Jiji Chen, Shih-Jong J. Lee, Lin Shao, Huafeng Liu, Kumaran S. Ramamurthi, Justin W. Taraska, Arpita Upadhyaya, Patrick La Riviere & Hari ShroffÂ

doi : 10.1038/s41587-022-01651-1

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Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine

Almut Heinken, Johannes Hertel, Geeta Acharya, Dmitry A. Ravcheev, Malgorzata Nyga, Onyedika Emmanuel Okpala, Marcus Hogan, Stefanía Magnúsdóttir, Filippo Martinelli, Bram Nap, German Preciat, Janaka N. Edirisinghe, Christopher S. Henry, Ronan M. T. Fleming & Ines ThieleÂ

doi : 10.1038/s41587-022-01628-0

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Droplet-based transcriptome profiling of individual synapses

Muchun Niu, Wenjian Cao, Yongcheng Wang, Qiangyuan Zhu, Jiayi Luo, Baiping Wang, Hui Zheng, David A. Weitz & Chenghang ZongÂ

doi : 10.1038/s41587-022-01635-1

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Author Correction: Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling

Caleb A. Lareau, Leif S. Ludwig, Christoph Muus, Satyen H. Gohil, Tongtong Zhao, Zachary Chiang, Karin Pelka, Jeffrey M. Verboon, Wendy Luo, Elena Christian, Daniel Rosebrock, Gad Getz, Genevieve M. Boland, Fei Chen, Jason D. Buenrostro, Nir Hacohen, Catherine J. Wu, Martin J. Aryee, Aviv Regev & Vijay G. SankaranÂ

doi : 10.1038/s41587-023-01942-1

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Author Correction: Guidelines for public database submission of uncultivated virus genome sequences for taxonomic classification

Evelien M. Adriaenssens, Simon Roux, J. Rodney Brister, Ilene Karsch-Mizrachi, Jens H. Kuhn, Arvind Varsani, Tong Yigang, Alejandro Reyes, Cédric Lood, Elliot J. Lefkowitz, Matthew B. Sullivan, Robert A. Edwards, Peter Simmonds, Luisa Rubino, Sead Sabanadzovic, Mart Krupovic & Bas E. DutilhÂ

doi : 10.1038/s41587-023-01952-z

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Bridging the gap in African biodiversity genomics and bioinformatics

Abdoallah Sharaf, Charlotte C. Ndiribe, Taiwo Crossby Omotoriogun, Linelle Abueg, Bouabid Badaoui, Fatu J. Badiane Markey, Girish Beedessee, Diaga Diouf, Vincent C. Duru, Chukwuike Ebuzome, Samuel C. Eziuzor, Yasmina Jaufeerally Fakim, Giulio Formenti, Nidhal Ghanmi, Fatma Zahra Guerfali, Isidore Houaga, Justin Eze Ideozu, Sally Mueni Katee, Slimane Khayi, Josiah O. Kuja, Emmanuel Hala Kwon-Ndung, Rose A. Marks, Acclaim M. Moila, Zahra Mungloo-Dilmohamud, Sadik Muzemil, Helen Nigussie, Julian O. Osuji, Verena Ras, Yves H. Tchiechoua, Yedomon Ange Bovys Zoclanclounon, Krystal A. Tolley, Cathrine Ziyomo, Ntanganedzeni Mapholi, Anne W. T. Muigai, Appolinaire Djikeng & ThankGod Echezona EbenezerÂ

doi : 10.1038/s41587-023-01933-2

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Five questions with Mor Nitzan

Julie Chuong 

doi : 10.1038/s41587-023-01926-1

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