Nature Reviews Drug Discovery




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The potential of innovative trial design for efficiently evaluating repurposed drugs

James M. S. Wason & Oliver Bandmann

doi : 10.1038/d41573-023-00129-2

Volume 22 Issue 9, September 2023

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Claudin-18.2 attracts the cancer crowd

Asher Mullard

doi : 10.1038/d41573-023-00120-x

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FDA approves long-acting RSV antibody

Asher Mullard

doi : 10.1038/d41573-023-00130-9

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Alnylam scores big pharma support for angiotensinogen silencer

Asher Mullard

doi : 10.1038/d41573-023-00131-8

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The high, and redundant, cost of failure in cancer drug development

Asher Mullard

doi : 10.1038/d41573-023-00132-7

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Chemoproteomic trailblazer advances covalent candidate into the clinic, pushes allosteric agenda

Asher Mullard

doi : 10.1038/d41573-023-00133-6

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Genomic medicines: the coming waves?

Wen Xie, Baiping Chen & John Wong

doi : 10.1038/d41573-023-00098-6

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Creating a path to splice-switching ASO therapies

Katie Kingwell

doi : 10.1038/d41573-023-00124-7

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Topoisomerase II inhibitor cures trypanosome infections

Sarah Crunkhorn

doi : 10.1038/d41573-023-00121-w

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APOBEC3A drives resistance

M. Teresa Villanueva

doi : 10.1038/d41573-023-00122-9

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Peptide vaccine turns up the heat in ALK-positive cancers

Alex Eccleston

doi : 10.1038/d41573-023-00123-8

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RNF41 reverses liver fibrosis

Sarah Crunkhorn

doi : 10.1038/d41573-023-00125-6

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A specific biomarker for insoluble tau

Sarah Crunkhorn

doi : 10.1038/d41573-023-00126-5

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Psychedelic treatment for anorexia

Sarah Crunkhorn

doi : 10.1038/d41573-023-00127-4

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Activating apoptosis in B cell lymphoma

Sarah Crunkhorn

doi : 10.1038/d41573-023-00128-3

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Small-molecule discovery through DNA-encoded libraries

Alexander A. Peterson & David R. LiuÂ

doi : 10.1038/s41573-023-00713-6

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The therapeutic potential of targeting regulated non-apoptotic cell death

Kamyar Hadian & Brent R. StockwellÂ

doi : 10.1038/s41573-023-00749-8

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Type 2 chronic inflammatory diseases: targets, therapies and unmet needs

Pavel Kolkhir, Cezmi A. Akdis, Mübeccel Akdis, Claus Bachert, Thomas Bieber, Giorgio Walter Canonica, Emma Guttman-Yassky, Martin Metz, Joaquim Mullol, Oscar Palomares, Harald Renz, Sonja Ständer, Torsten Zuberbier & Marcus MaurerÂ

doi : 10.1038/s41573-023-00750-1

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