doi : 10.1111/jocd.14218
Volume20, Issue6June 2021Pages i-i
The cover image is based on the Original Contributon Helium plasma dermal resurfacing: VISIA CR assessment of facial spots,pores, and wrinkles-Preliminary findings by John David Holcomb
Michael H. Gold MD
doi : 10.1111/jocd.14196
Volume20, Issue6June 2021Pages 1565-1565
Ecem Bostan MD, Basak Yalici-Armagan MD
doi : 10.1111/jocd.14035
Volume20, Issue6June 2021Pages 1566-1567
Mustafa Gundogdu MD, Gokturk Dere MD
doi : 10.1111/jocd.14044
Volume20, Issue6June 2021Pages 1568-1570
To investigate whether acne treatment agent systemic isotretinoin causes susceptibility to COVID-19 disease.
Mohamed L. Elsaie MD, Eman A. Youssef MD
doi : 10.1111/jocd.14101
Volume20, Issue6June 2021Pages 1571-1572
Mohamed H.M. EL-Komy MD, Asmaa Abdelnaby MD, Mona El-Kalioby MD
doi : 10.1111/jocd.14104
Volume20, Issue6June 2021Pages 1573-1579
Psoriasis is a chronic skin disease that needs continuous medical care. During COVID-19, delivering medical service was negatively affected.
Abanoub Riad DDS, Esraa Gomaa DDS, Barbora Hockova DDS, Miloslav Klugar PhD
doi : 10.1111/jocd.14066
Volume20, Issue6June 2021Pages 1580-1584
George Kroumpouzos MD, Martin Kassir MD, Mrinal Gupta MD, Anant Patil MD, Mohamad Goldust MD
doi : 10.1111/jocd.14160
Volume20, Issue6June 2021Pages 1585-1590
Cosmetic surgery procedures have increased manifolds all over the world owing to the ever-increasing demand of people to look beautiful and young. Injectable treatments like botulinum toxin are becoming more popular owing to their rapid, well-defined, and lasting results for the reduction of facial fine lines, wrinkles, and facial rejuvenation.
Adriano Santorelli MD, Fabio Cerullo MD, Pierfrancesco Cirillo MD, Maurizio Cavallini MD, Stefano Avvedimento MD
doi : 10.1111/jocd.14038
Volume20, Issue6June 2021Pages 1591-1597
Minimally invasive procedures, such as thread suspension techniques, are a growing trend for facial rejuvenation. However, not enough data are available on the efficacy, outcomes, and morbidity of suture suspension techniques in mid-face reshaping.
Marie Meunier MS, Emilie Chapuis BS, Laura Lapierre BS, Pascale Auriol BS, Chantal Paulus BS, Boris Elbaum BS, Eglantine Don Simoni MS, Jérôme Sandré MD, Daniel Auriol PhD, Amandine Scandolera PhD, Romain Reynaud MS
doi : 10.1111/jocd.14000
Volume20, Issue6June 2021Pages 1598-1610
The dermis is composed of a tangle of macromolecules that provides the skin its biomechanical properties. During chronological aging, fibroblasts lose their ability to synthesize collagen and an accumulation of matrix metalloproteinases leads to an increase in collagen degradation. As a result, there is a decline in the biomechanical properties of the skin. Skin aging is accelerated by external factors such as UV radiation and pollution, which induce accumulation of oxidants, and so of oxidized proteins in the skin.
Xi Chen MM, Quansheng Lu MM, Can Chen MB, Guan Jiang PhD
doi : 10.1111/jocd.13846
Volume20, Issue6June 2021Pages 1611-1617
Dermoscopy is considered to be a bridge between clinical observation and histopathological examination, allowing the in vivo examination of skin microstructures that are not visible to the naked eye, from the epidermis to the superficial dermis.
Tanya Greywal MD, Steven H. Dayan MD, Kate Goldie MD, Sabrina Guillen Fabi MD
doi : 10.1111/jocd.13785
Volume20, Issue6June 2021Pages 1618-1621
Since there is no universal standard of beauty, each aesthetic provider's definition may shape his/her practice of aesthetic procedures.
B?rbara Roque Ferreira MD, Mohammad Jafferany MD
doi : 10.1111/jocd.14112
Volume20, Issue6June 2021Pages 1622-1624
Currently, psychodermatological disorders are classified under different criteria exhibiting several limitations, and no single universal classification system exists.
Sebastian Cotofana MD, PhD, Angela P. Pedraza MD, Joely Kaufman MD, Luiz E.T. Avelar MD, Diana L. Gavril MD, Claudia A. Hernandez MD, Emy C. Onishi MD, Andreas Nikolis MD, Thais Sakuma MD, Konstantin Frank MD
doi : 10.1111/jocd.14133
Volume20, Issue6June 2021Pages 1625-1633
Current injection algorithms for treating the glabella rely on a five- or seven-point injection technique with possible medial eyebrow ptosis and lateral eyebrow elevation as undesirable outcomes.
Daniel S. Müller MD, MBA, Valentina Prinz MBA, Monika Sulovsky MD, Mia Cajkovsky, Sebastian Cotofana MD, PhD, Konstantin Frank MD
doi : 10.1111/jocd.14109
Volume20, Issue6June 2021Pages 1634-1642
A plethora of age-related changes contribute to hollowing of the temples, as bone remodeling, atrophy of the temporalis muscle, thinning of the skin, and deflation of the subcutaneous and deep temporal fat create the appearance of a skeletonized face. In addition, previous studies have established a relationship between facial skeletonization, temporal hollowing, and postmenopausal sarcopenia.
Henry R. Wolfe PhD, Elizabeth Rosenberg MSN, RN, FNP, Kadriye Ciftci MD, PhD, Jill Edgecombe BS, Michael P. McLane PhD
doi : 10.1111/jocd.14078
Volume20, Issue6June 2021Pages 1643-1647
Collagenase clostridium histolyticum (CCH-aesthetic formulation [CCH-aaes]; QWO™ [Endo Aesthetics, Malvern PA, USA] is approved as a subcutaneous injection for treatment of cellulite. In the aesthetic practice, dilution of marketed products is commonly employed to tailor treatments to individual patients or off-label locations. Dilution beyond the 0.23 mg/ml achievable with the proprietary diluent supplied with the CCH-aaes lyophilized powder requires diluents readily available in clinic.
Or Friedman MD, Roei Singolda MD, Joseph N. Mehrabi MD, Ofir Artzi MD, Ricardo Frotta Boggio MD, PhD, Adriano Mesquita Bento MD
doi : 10.1111/jocd.14152
Volume20, Issue6June 2021Pages 1648-1654
Botulinum neurotoxin is one of the most versatile and widely used medical products in the world.
Sachin M. Shridharani MD FACS, Grace M. Tisch BA, Trina G. Ebersole MD, Teri N. Moak MS, MD, Carolina Edwartz PhD
doi : 10.1111/jocd.14141
Volume20, Issue6June 2021Pages 1655-1662
Clinical data on body contouring with injectable poly-L-lactic acid are sparsely reported in published literature. This study describes the lead author's clinical experience using injectable poly-L-lactic acid for body contouring in various anatomic locations.
Jordan V. Wang MD, MBE, MBA, Robert D. Murgia DO, MA, Claire Noell MD, Nazanin Saedi MD, Christopher B. Zachary MBBS, FRCP, Robert Weiss MD, Roy G. Geronemus MD
doi : 10.1111/jocd.14129
Volume20, Issue6June 2021Pages 1663-1667
Non-invasive body contouring has experienced recent growth. To meet demand, medical spas and non-physician operators have grown. Insights into their practice can provide information on their impact.
John David Holcomb MD
doi : 10.1111/jocd.14106
Volume20, Issue6June 2021Pages 1668-1678
Effects of low energy, single-pass helium plasma dermal resurfacing (PDR) treatment on brown spots, enlarged pores, and wrinkles—preliminary findings.
Efrat Solomon-Cohen MD, MOccH, Moshe Lapidoth MD, MPH, Daniel Mimouni MD, Lehavit Akerman MD, Dan Slodownik MD, Emmilia Hodak MD, Assi Levi MD
doi : 10.1111/jocd.13958
Volume20, Issue6June 2021Pages 1679-1683
Laser treatments for facial rejuvenation are common, with ablative modalities being of more common use for this indication. Efficient nonablative modalities are of rising demand.
Ranj Hussien Arif MSc, Fadil Abdullah Kareem PhD, Faraedon M. Zardawi PhD, Tamara Sardar Al-Karadaghi PhD
doi : 10.1111/jocd.13733
Volume20, Issue6June 2021Pages 1684-1691
Gingival hyper-pigmentation is an esthetics problem in patients with excessive gingival display. Laser ablation has been suggested recently as the most effective, pleasant, and reliable technique for gingival depigmentation compared to blade surgery.
Min Wei MD, Li Li MD, Xiao Feng Zhang MD, Mengna Li MD, Baoxi Wang MD, Yan Yan MD
doi : 10.1111/jocd.13735
Volume20, Issue6June 2021Pages 1692-1699
Inflammation and postinflammatory hyperpigmentation (PIH) are two adverse side effects of ablative fractional CO2 laser (ablative Fr CO2) treatment for both rejuvenation and acne scars.
Suparuj Lueangarun MD, MSc, Chutimon Namboonlue MD, MSc, Therdpong Tempark MD
doi : 10.1111/jocd.13756
Volume20, Issue6June 2021Pages 1700-1708
The potential efficacy of vascular component-targeted laser has been evaluated for the treatment of melasma, which commonly found with the co-existence of telangiectasia.
Dehua Liu MD, Eray Yihui Zhou MD, Dian Chen MD, Hsiaohan Tuan MD, Yi Zhao MD
doi : 10.1111/jocd.13766
Volume20, Issue6June 2021Pages 1709-1713
Epidermoid cyst (EC) is a common and benign tumor, which can occur anywhere on the skin. Surgical excision is usually considered as the first-line treatment. However, linear scars arising after excision for EC remain a cosmetic problem.
Patr?cia Barbosa PT, Catarina Coimbra PT, Andreia Noites PhD, MSc, PT, Rui Vilarinho MSc, PT, Paulo Carvalho PhD, MSc, PT, Manuela Amorim MSc, CB, Teresa Moreira CB, Cristina Melo PhD, MSc, PT
doi : 10.1111/jocd.13781
Volume20, Issue6June 2021Pages 1714-1723
Increased abdominal fat and sedentary lifestyles contribute to cardiovascular disease risk. The combination of exercise and low-level laser therapy (LLLT) appears to be an innovative method to increase the lipolytic rate of abdominal adipocytes, in order to reduce abdominal fat.
Vasanop Vachiramon MD, Kanchana Leerunyakul MD, MSc, Chaninan Kositkuljorn MD, Pamela Chayavichitsilp MD
doi : 10.1111/jocd.13790
Volume20, Issue6June 2021Pages 1724-1731
Isobutylamido thiazolyl resorcinol (ITR) is a novel anti-tyrosinase recently shown to be effective in the treatment of hyperpigmentation. Low-fluence Q-switched Nd:YAG 1064-nm laser (LFQS) has proven to be effective for various hyperpigmentary conditions. However, there is no study on the efficacy and safety of combined ITR and LFQS treatment.
Sara Troia PT, Ana Maria Moreira PT, Daniela Pisco PT, Andreia Noites PhD, MSc, PT, Ana Luisa Vale PT, Paulo Carvalho PhD, MSc, PT, Rui Vilarinho MSc, PT
doi : 10.1111/jocd.13791
Volume20, Issue6June 2021Pages 1732-1742
Cellulite is a multifactor and controversial condition. Several methods have been explored to reduce it, not always with favorable results. Shock Wave Therapy has been shown to be effective, but the results of its association with an Aerobic Exercise Program are unknown.
Doaa A. Mahgoub MD, Tamarah I. Dhannoon MBBCh, Marwa S. El-Mesidy MD
doi : 10.1111/jocd.13749
Volume20, Issue6June 2021Pages 1743-1749
Intralesional corticosteroids (ILCs) is the first-line therapy for patients older than 10 years having patchy alopecia areata, however some patients do not respond effectively.
Hayder R. Al-Hamamy MBChB, DDV, CABD, PhD, Muhsin A. AL-Dhalimi MBChB, DDV, CABD, FICMS, Azhar F. Abtan MBChB, FICMS
doi : 10.1111/jocd.13754
Volume20, Issue6June 2021Pages 1750-1755
Acne scars are common problems encountered in daily dermatologic practice.
Yajing Cao MD, Peiru Wang MD, Guolong Zhang MD, Chan Hu MD, Haiyan Zhang MD, Xiuli Wang MD, PhD
doi : 10.1111/jocd.13798
Volume20, Issue6June 2021Pages 1756-1762
Laser therapies have brought dawn to refractory skin diseases, but also were accompanied by postlaser inflammation and skin barrier dysfunction. To recover skin function quickly, the research and development of active ingredients including ?-glucan for postlaser repair have attracted much attention.
Debraj Shome MD, FRCS, FACS, FAACS, MBA, Rinky Kapoor MD, Komal Doshi MDS, Ghanshyam Patel PhD, Sapna Vadera MDS, Vaibhav Kumar MDS
doi : 10.1111/jocd.14154
Volume20, Issue6June 2021Pages 1763-1765
no abstract
Valeria Campos Dermatologist, MD at Universidade de S?o Paulo (USP), Luiza Pitassi Dermatologist, MD, PhD at Universidade Estadual de Campinas (UNICAMP), Célia Kalil Dermatologist, PhD at Universidade Federal do Rio Grande do Sul (UFRGS), José Euzébio Gonçalves J?nior Bachelor in Pharmacy at Universidade Federal do Rio de Janeiro (UFRJ), Beatriz Sant’Anna MD at (Universidade Federal do Rio de Janeiro (UFRJ), Priscila Correia Bachelor in Pharmacy at Universidade Federal Fluminense (USP)
doi : 10.1111/jocd.14016
Volume20, Issue6June 2021Pages 1766-1773
Acne is a chronic disease that affects the pilosebaceous follicle and is characterized by the presence of non-inflammatory and/or inflammatory lesions, affecting both adolescents and adults. Inflammatory acne lesions are capable to increase their melanin production and promote a post-inflammatory hyperchromia.
Young In Lee MD, Soomin Kim PhD, Jihee Kim MD, Jemin Kim MD, Kyung Bae Chung MD, Ju Hee Lee MD, PhD
doi : 10.1111/jocd.13767
Volume20, Issue6June 2021Pages 1774-1781
Recent advancements in laser-assisted drug delivery have emphasized the importance of post-laser use of active ingredients.
Radwa El-Sayed Mahmoud Marie MD, Aya Qamar Eldawla Mahmoud Abuzeid MD, Fadia M. Attia MD, Maha Mohamed Anani MD, Amal H. A. Gomaa MD, Lina M. Atef MD
doi : 10.1111/jocd.13779
Volume20, Issue6June 2021Pages 1782-1787
Warts are viral cutaneous infections caused by human papilloma virus (HPV), presented by verrucous growth over the skin surface. The immune response is considered to play a crucial role in HPV clearance.
Céline Couteau PhD, Coraline Dupont PharmD, Eva Paparis BHlthSci, Laurence J. M. Coiffard PhD
doi : 10.1111/jocd.13783
Volume20, Issue6June 2021Pages 1788-1794
Following a growing mistrust in a certain number of ingredients used by the cosmetic industry, it has become popular in recent years for consumers to make their own products at home.
Neda Bavarsad PharmD, PhD, Mohammad Ali Mapar MD, Mona Safaezadeh PharmD, Seyed Mahmoud Latifi PhD
doi : 10.1111/jocd.13799
Volume20, Issue6June 2021Pages 1795-1800
Melasma is an acquired hyperpigmentation disorder, and reactive oxygen species play important role in regulating melanin synthesis. Lycopene is one of the most effective oxygen neutralizers among tomato-derived carotenoids.
Abd El-Aziz Ibrahim El-Taweel MD, Abdul-Aziz Abdul-Salam Ahmed Al-Refaie MD, Khalid Hamdy Awad Salem MBBcH, Rehab Mohammed Salem MD
doi : 10.1111/jocd.13800
Volume20, Issue6June 2021Pages 1801-1806
Topical ?-blockers, propranolol, and timolol were used for pyogenic granuloma (PG) treatment; however, their efficacies and safety profiles were not compared.
Didem Dincer, Efsun Tanacan, Cansel Kose Ozkan
doi : 10.1111/jocd.13812
Volume20, Issue6June 2021Pages 1807-1809
Alopecia areata (AA) is an autoimmune nonscarring alopecic disorder, which presents with varying amounts of hair loss, ranging from focal patchy loss to entire scalp and body hair loss.
Zoran ?galjardi? MD, PhD, Ivonne ?galjardi? MD, Filip Juri? MD
doi : 10.1111/jocd.13740
Volume20, Issue6June 2021Pages 1810-1812
Anatomy of the periorbital region is very complex. Malar oedema/mounds/festoons often remain unaddressed. There are various treatments proposed for this pathologic entity as well as non-standardized nomenclature. Implementation of technology in aesthetic medicine and surgery resulted in novel treatments for this entity.
doi : 10.1111/jocd.13737
Volume20, Issue6June 2021Pages 1813-1820
Acral lentiginous melanoma (ALM) carries one of the worst prognoses among other subtypes. This malignant tumor is found on the distal limbs and is usually detected at late stages. Hereby, the authors present their experience on this melanoma subtype.
doi : 10.1111/jocd.13738
Volume20, Issue6June 2021Pages 1821-1826
Scalp is comprised of five layers namely skin, connective tissue, aponeurosis, loose areolar tissue, and periosteum, each having distinct characteristics. The scalp mobility plays an important role in scalp wound closure. Thus, the estimation of scalp mobility is necessary to obtain a tension-free closure and fine scar in hair restoration surgery.
doi : 10.1111/jocd.13739
Volume20, Issue6June 2021Pages 1827-1836
Trichoscopy is a useful tool for diagnosis and follow-up of alopecia areata (AA) patients. Both platelet-rich plasma (PRP) and intralesional corticosteroids (ILCs) are important treatment modalities of patchy AA.
doi : 10.1111/jocd.13782
Volume20, Issue6June 2021Pages 1837-1845
Many patients consult a specialist in esthetics to improve certain aspects of their face that are altered by aging. To ensure optimal results and to define the best approach for such interventions, it is important that specialists have a comprehensive understanding of facial anatomy and of the aging process in the regions of interest.
doi : 10.1111/jocd.14142
Volume20, Issue6June 2021Pages 1846-1848
The increased popularity of periocular cosmetic applications in recent years has resulted in the appearance of various complications. The cosmetic eyelash lifting is one of these new techniques and is gradually becoming more popular. There are no previous reports of any complications of this procedure in the literature.
doi : 10.1111/jocd.14065
Volume20, IssueJune 2021Pages 1849-1854
The FDA maintains the Adverse Event Reporting System (CAERS) database, which contains product complaint reports for foods, dietary supplements, and cosmetics. Product line perception and subsequent adverse event reporting may be impacted by negative media attention.
doi : 10.1111/jocd.13732
Volume20, Issue6June 2021Pages 1855-1859
Androgenetic alopecia (AGA) is the most common type of hair loss and affects approximately 50% of the male population.
doi : 10.1111/jocd.13747
Volume20, Issue6June 2021Pages 1860-1866
The etiology of premature hair graying (PHG) remains incompletely understood with limited treatment options, although has profound impacts on patient’s quality of life.
doi : 10.1111/jocd.13750
Volume20, Issue6June 2021Pages 1867-1874
Microneedling in combination with the use of growth factors can help with a range of indications, including skin rejuvenation. There is an increase in request for safe minimally invasive procedures with no-to-minimal downtime. This procedure offers regeneration and is becoming popular as part of the regenerative, minimally invasive era.
doi : 10.1111/jocd.13760
Volume20, Issue6June 2021Pages 1875-1884
Recent researches had reported that microRNAs (miRNAs) played a role in skin photoaging. Our previous study found that long noncoding RNA (lncRNA) expression was changed in the UVA-irradiated skin fibroblasts, but the regulating network of noncoding RNA in UV-induced skin changes has not been elucidated well. Here, we investigated the interactions of miRNA-lncRNA-mRNAs in skin photoaging mechanisms.
doi : 10.1111/jocd.13761
Volume20, Issue6June 2021Pages 1885-1888
Scars are often considered to be skin problems that affect beauty. The tension acting on the edge of the wound is the main factor causing the scar hyperplasia. At present, the clinical use of botulinum toxin A (BTX-A) around the wound to cause transient muscle paralysis reduce the muscle movement around the wound and wound tension to prevent scar hyperplasia during wound healing.
doi : 10.1111/jocd.13762
Volume20, Issue6June 2021Pages 1889-1896
Recent studies have reported that the incidence of acne combined with rosacea is increasing. However, the clinical feature and inducing factor of these two diseases co-occurrence is remain unclear.
doi : 10.1111/jocd.13764
Volume20, Issue6June 2021Pages 1897-1899
Delayed pressure urticaria is a rare form of chronic inducible urticaria characterized by erythematous-painful plaques that develop in areas of the skin exposed to prolonged pressure. Its treatment is very difficult, and its response to antihistamines is variable. Cases of delayed pressure urticaria, which have been completely controlled with the use of omalizumab in recent years, have been reported.
doi : 10.1111/jocd.13769
Volume20, Issue6June 2021Pages 1900-1905
Topical antifungals are the most commonly used therapy in white piedra of the scalp. However, persistence and relapse of infection still pose a significant challenge. Systemic antifungals have been recommended to enhance the therapeutic response.
doi : 10.1111/jocd.13772
Volume20, Issue6June 2021Pages 1906-1914
Vitiligo is an acquired depigmentation of the skin and the mucous membranes, exhibited as white macules and patches due to selective loss of melanocytes. Etiological theories of vitiligo include genetic, immunological, neurohormonal, cytotoxic, biochemical, oxidative stress, and newer theories of melanocytorrhagy and diminished melanocytes survival. It has been revealed that liver X receptor alpha gene is expressed in skin tissue such as sebaceous glands, hair follicle, keratinocytes, and fibroblasts and is linked to various skin disorders as acne vulgaris and psoriasis.
doi : 10.1111/jocd.13777
Volume20, Issue6June 2021Pages 1915-1922
Many patients with atopic dermatitis (AD) know that harsh rubbing of their skin might worsen their skin symptoms. They consider that the force they use to rub their skin when removing their makeup cosmetics should not be hard and their cleansing habits could worsen their skin symptoms. However, we presume that the force they use to rub their skin may still be strong and might worsen their skin symptoms.
doi : 10.1111/jocd.13780
Volume20, Issue6June 2021Pages 1923-1932
The leaves of Tasmannia lanceolata mainly contain polygodial that is known to exhibit a range of biological functions including anti-inflammatory effects.
doi : 10.1111/jocd.13789
Volume20, Issue6June 2021Pages 1933-1941
At present, it is no longer possible to use animal testing for ingredients and cosmetic products in the Organisation for Economic Co-operation and Development (OECD) member states. However, in vitro tests are widely used to determine the safety and efficacy of ingredients and medicines.
doi : 10.1111/jocd.13748
Volume20, Issue6June 2021Pages 1942-1943
doi : 10.1111/jocd.13758
Volume20, Issue6June 2021Pages 1944-1945
doi : 10.1111/jocd.13778
Volume20, Issue6June 2021Pages 1946-1947
doi : 10.1111/jocd.13784
Volume20, Issue6June 2021Pages 1948-1950
doi : 10.1111/jocd.14155
Volume20, Issue6June 2021Pages 1951-1952
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