Journal of Cosmetic Dermatology




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Cover Image

doi : 10.1111/jocd.14218

Volume20, Issue6June 2021Pages i-i

The cover image is based on the Original Contributon Helium plasma dermal resurfacing: VISIA CR assessment of facial spots,pores, and wrinkles-Preliminary findings by John David Holcomb

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Issue Information

doi : 10.1111/jocd.14219

Volume20, Issue6June 2021Pages 1563-1564

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JCD Editorial—June 2021

Michael H. Gold MD

doi : 10.1111/jocd.14196

Volume20, Issue6June 2021Pages 1565-1565

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Herpes zoster following inactivated COVID-19 vaccine: A coexistence or coincidence?

Ecem Bostan MD, Basak Yalici-Armagan MD

doi : 10.1111/jocd.14035

Volume20, Issue6June 2021Pages 1566-1567

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Is systemic isotretinoin use a risk factor for coronavirus disease 2019 (COVID-19)?

Mustafa Gundogdu MD, Gokturk Dere MD

doi : 10.1111/jocd.14044

Volume20, Issue6June 2021Pages 1568-1570

To investigate whether acne treatment agent systemic isotretinoin causes susceptibility to COVID-19 disease.

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Interest in aesthetics during COVID-19 pandemic: A Google trends analysis

Mohamed L. Elsaie MD, Eman A. Youssef MD

doi : 10.1111/jocd.14101

Volume20, Issue6June 2021Pages 1571-1572

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How does COVID-19 impact psoriasis practice, prescription patterns, and healthcare delivery for psoriasis patients? A cross-sectional survey study

Mohamed H.M. EL-Komy MD, Asmaa Abdelnaby MD, Mona El-Kalioby MD

doi : 10.1111/jocd.14104

Volume20, Issue6June 2021Pages 1573-1579

Psoriasis is a chronic skin disease that needs continuous medical care. During COVID-19, delivering medical service was negatively affected.

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Oral candidiasis of COVID-19 patients: Case report and review of evidence

Abanoub Riad DDS, Esraa Gomaa DDS, Barbora Hockova DDS, Miloslav Klugar PhD

doi : 10.1111/jocd.14066

Volume20, Issue6June 2021Pages 1580-1584

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Complications of Botulinum toxin A: An update review

George Kroumpouzos MD, Martin Kassir MD, Mrinal Gupta MD, Anant Patil MD, Mohamad Goldust MD

doi : 10.1111/jocd.14160

Volume20, Issue6June 2021Pages 1585-1590

Cosmetic surgery procedures have increased manifolds all over the world owing to the ever-increasing demand of people to look beautiful and young. Injectable treatments like botulinum toxin are becoming more popular owing to their rapid, well-defined, and lasting results for the reduction of facial fine lines, wrinkles, and facial rejuvenation.

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Mid-face reshaping using threads with bidirectional convergent barbs: A retrospective study

Adriano Santorelli MD, Fabio Cerullo MD, Pierfrancesco Cirillo MD, Maurizio Cavallini MD, Stefano Avvedimento MD

doi : 10.1111/jocd.14038

Volume20, Issue6June 2021Pages 1591-1597

Minimally invasive procedures, such as thread suspension techniques, are a growing trend for facial rejuvenation. However, not enough data are available on the efficacy, outcomes, and morbidity of suture suspension techniques in mid-face reshaping.

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Mannose-6-phosphate complex and improvement in biomechanical properties of the skin

Marie Meunier MS, Emilie Chapuis BS, Laura Lapierre BS, Pascale Auriol BS, Chantal Paulus BS, Boris Elbaum BS, Eglantine Don Simoni MS, Jérôme Sandré MD, Daniel Auriol PhD, Amandine Scandolera PhD, Romain Reynaud MS

doi : 10.1111/jocd.14000

Volume20, Issue6June 2021Pages 1598-1610

The dermis is composed of a tangle of macromolecules that provides the skin its biomechanical properties. During chronological aging, fibroblasts lose their ability to synthesize collagen and an accumulation of matrix metalloproteinases leads to an increase in collagen degradation. As a result, there is a decline in the biomechanical properties of the skin. Skin aging is accelerated by external factors such as UV radiation and pollution, which induce accumulation of oxidants, and so of oxidized proteins in the skin.

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Recent developments in dermoscopy for dermatology

Xi Chen MM, Quansheng Lu MM, Can Chen MB, Guan Jiang PhD

doi : 10.1111/jocd.13846

Volume20, Issue6June 2021Pages 1611-1617

Dermoscopy is considered to be a bridge between clinical observation and histopathological examination, allowing the in vivo examination of skin microstructures that are not visible to the naked eye, from the epidermis to the superficial dermis.

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The perception bias of aesthetic providers

Tanya Greywal MD, Steven H. Dayan MD, Kate Goldie MD, Sabrina Guillen Fabi MD

doi : 10.1111/jocd.13785

Volume20, Issue6June 2021Pages 1618-1621

Since there is no universal standard of beauty, each aesthetic provider's definition may shape his/her practice of aesthetic procedures.

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Classification of psychodermatological disorders

B?rbara Roque Ferreira MD, Mohammad Jafferany MD

doi : 10.1111/jocd.14112

Volume20, Issue6June 2021Pages 1622-1624

Currently, psychodermatological disorders are classified under different criteria exhibiting several limitations, and no single universal classification system exists.

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Respecting upper facial anatomy for treating the glabella with neuromodulators to avoid medial brow ptosis—A refined 3-point injection technique

Sebastian Cotofana MD, PhD, Angela P. Pedraza MD, Joely Kaufman MD, Luiz E.T. Avelar MD, Diana L. Gavril MD, Claudia A. Hernandez MD, Emy C. Onishi MD, Andreas Nikolis MD, Thais Sakuma MD, Konstantin Frank MD

doi : 10.1111/jocd.14133

Volume20, Issue6June 2021Pages 1625-1633

Current injection algorithms for treating the glabella rely on a five- or seven-point injection technique with possible medial eyebrow ptosis and lateral eyebrow elevation as undesirable outcomes.

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Volumization of the young and the old temple using a highly cross-linked HA filler

Daniel S. Müller MD, MBA, Valentina Prinz MBA, Monika Sulovsky MD, Mia Cajkovsky, Sebastian Cotofana MD, PhD, Konstantin Frank MD

doi : 10.1111/jocd.14109

Volume20, Issue6June 2021Pages 1634-1642

A plethora of age-related changes contribute to hollowing of the temples, as bone remodeling, atrophy of the temporalis muscle, thinning of the skin, and deflation of the subcutaneous and deep temporal fat create the appearance of a skeletonized face. In addition, previous studies have established a relationship between facial skeletonization, temporal hollowing, and postmenopausal sarcopenia.

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Evaluation of alternative diluents for clinical use of collagenase clostridium histolyticum (CCH-aaes)

Henry R. Wolfe PhD, Elizabeth Rosenberg MSN, RN, FNP, Kadriye Ciftci MD, PhD, Jill Edgecombe BS, Michael P. McLane PhD

doi : 10.1111/jocd.14078

Volume20, Issue6June 2021Pages 1643-1647

Collagenase clostridium histolyticum (CCH-aesthetic formulation [CCH-aaes]; QWO™ [Endo Aesthetics, Malvern PA, USA] is approved as a subcutaneous injection for treatment of cellulite. In the aesthetic practice, dilution of marketed products is commonly employed to tailor treatments to individual patients or off-label locations. Dilution beyond the 0.23 mg/ml achievable with the proprietary diluent supplied with the CCH-aaes lyophilized powder requires diluents readily available in clinic.

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Current use of botulinum neurotoxin in esthetic practice—Clinical guide and review

Or Friedman MD, Roei Singolda MD, Joseph N. Mehrabi MD, Ofir Artzi MD, Ricardo Frotta Boggio MD, PhD, Adriano Mesquita Bento MD

doi : 10.1111/jocd.14152

Volume20, Issue6June 2021Pages 1648-1654

Botulinum neurotoxin is one of the most versatile and widely used medical products in the world.

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Clinical experience of poly-L-lactic acid injections for body contouring treatment

Sachin M. Shridharani MD FACS, Grace M. Tisch BA, Trina G. Ebersole MD, Teri N. Moak MS, MD, Carolina Edwartz PhD

doi : 10.1111/jocd.14141

Volume20, Issue6June 2021Pages 1655-1662

Clinical data on body contouring with injectable poly-L-lactic acid are sparsely reported in published literature. This study describes the lead author's clinical experience using injectable poly-L-lactic acid for body contouring in various anatomic locations.

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National market analysis for body contouring providers: Medical spas and physician practices

Jordan V. Wang MD, MBE, MBA, Robert D. Murgia DO, MA, Claire Noell MD, Nazanin Saedi MD, Christopher B. Zachary MBBS, FRCP, Robert Weiss MD, Roy G. Geronemus MD

doi : 10.1111/jocd.14129

Volume20, Issue6June 2021Pages 1663-1667

Non-invasive body contouring has experienced recent growth. To meet demand, medical spas and non-physician operators have grown. Insights into their practice can provide information on their impact.

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Helium plasma dermal resurfacing: VISIA CR assessment of facial spots, pores, and wrinkles—Preliminary findings

John David Holcomb MD

doi : 10.1111/jocd.14106

Volume20, Issue6June 2021Pages 1668-1678

Effects of low energy, single-pass helium plasma dermal resurfacing (PDR) treatment on brown spots, enlarged pores, and wrinkles—preliminary findings.

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1540-nm fractional erbium: Glass laser is a safe and effective modality for nonablative facial rejuvenation

Efrat Solomon-Cohen MD, MOccH, Moshe Lapidoth MD, MPH, Daniel Mimouni MD, Lehavit Akerman MD, Dan Slodownik MD, Emmilia Hodak MD, Assi Levi MD

doi : 10.1111/jocd.13958

Volume20, Issue6June 2021Pages 1679-1683

Laser treatments for facial rejuvenation are common, with ablative modalities being of more common use for this indication. Efficient nonablative modalities are of rising demand.

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Efficacy of 980 nm diode laser and 2940 nm Er: YAG laser in gingival depigmentation: A comparative study

Ranj Hussien Arif MSc, Fadil Abdullah Kareem PhD, Faraedon M. Zardawi PhD, Tamara Sardar Al-Karadaghi PhD

doi : 10.1111/jocd.13733

Volume20, Issue6June 2021Pages 1684-1691

Gingival hyper-pigmentation is an esthetics problem in patients with excessive gingival display. Laser ablation has been suggested recently as the most effective, pleasant, and reliable technique for gingival depigmentation compared to blade surgery.

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Fusidic acid cream comparatively minimizes signs of inflammation and postinflammatory hyperpigmentation after ablative fractional CO2 laser resurfacing in Chinese patients: A randomized controlled trial

Min Wei MD, Li Li MD, Xiao Feng Zhang MD, Mengna Li MD, Baoxi Wang MD, Yan Yan MD

doi : 10.1111/jocd.13735

Volume20, Issue6June 2021Pages 1692-1699

Inflammation and postinflammatory hyperpigmentation (PIH) are two adverse side effects of ablative fractional CO2 laser (ablative Fr CO2) treatment for both rejuvenation and acne scars.

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Postinflammatory and rebound hyperpigmentation as a complication after treatment efficacy of telangiectatic melasma with 585 nanometers Q-switched Nd: YAG laser and 4% hydroquinone cream in skin phototypes III-V

Suparuj Lueangarun MD, MSc, Chutimon Namboonlue MD, MSc, Therdpong Tempark MD

doi : 10.1111/jocd.13756

Volume20, Issue6June 2021Pages 1700-1708

The potential efficacy of vascular component-targeted laser has been evaluated for the treatment of melasma, which commonly found with the co-existence of telangiectasia.

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Epidermoid cyst removal with CO2 laser fenestration: A retrospective cohort study

Dehua Liu MD, Eray Yihui Zhou MD, Dian Chen MD, Hsiaohan Tuan MD, Yi Zhao MD

doi : 10.1111/jocd.13766

Volume20, Issue6June 2021Pages 1709-1713

Epidermoid cyst (EC) is a common and benign tumor, which can occur anywhere on the skin. Surgical excision is usually considered as the first-line treatment. However, linear scars arising after excision for EC remain a cosmetic problem.

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Effect of one session of aerobic exercise associated with abdominal laser therapy in lipolytic activity, lipid profile, and inflammatory markers

Patr?cia Barbosa PT, Catarina Coimbra PT, Andreia Noites PhD, MSc, PT, Rui Vilarinho MSc, PT, Paulo Carvalho PhD, MSc, PT, Manuela Amorim MSc, CB, Teresa Moreira CB, Cristina Melo PhD, MSc, PT

doi : 10.1111/jocd.13781

Volume20, Issue6June 2021Pages 1714-1723

Increased abdominal fat and sedentary lifestyles contribute to cardiovascular disease risk. The combination of exercise and low-level laser therapy (LLLT) appears to be an innovative method to increase the lipolytic rate of abdominal adipocytes, in order to reduce abdominal fat.

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Combined isobutylamido thiazolyl resorcinol and low-fluence Q-switched Nd: YAG laser for the treatment of facial hyperpigmentation: A randomized, split-face study

Vasanop Vachiramon MD, Kanchana Leerunyakul MD, MSc, Chaninan Kositkuljorn MD, Pamela Chayavichitsilp MD

doi : 10.1111/jocd.13790

Volume20, Issue6June 2021Pages 1724-1731

Isobutylamido thiazolyl resorcinol (ITR) is a novel anti-tyrosinase recently shown to be effective in the treatment of hyperpigmentation. Low-fluence Q-switched Nd:YAG 1064-nm laser (LFQS) has proven to be effective for various hyperpigmentary conditions. However, there is no study on the efficacy and safety of combined ITR and LFQS treatment.

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Effect of shock wave therapy associated with aerobic exercise on cellulite: A randomized controlled trial

Sara Troia PT, Ana Maria Moreira PT, Daniela Pisco PT, Andreia Noites PhD, MSc, PT, Ana Luisa Vale PT, Paulo Carvalho PhD, MSc, PT, Rui Vilarinho MSc, PT

doi : 10.1111/jocd.13791

Volume20, Issue6June 2021Pages 1732-1742

Cellulite is a multifactor and controversial condition. Several methods have been explored to reduce it, not always with favorable results. Shock Wave Therapy has been shown to be effective, but the results of its association with an Aerobic Exercise Program are unknown.

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Trichloroacetic acid 35% as a therapeutic line for localized patchy alopecia areata in comparison with intralesional steroids: Clinical and trichoscopic evaluation

Doaa A. Mahgoub MD, Tamarah I. Dhannoon MBBCh, Marwa S. El-Mesidy MD

doi : 10.1111/jocd.13749

Volume20, Issue6June 2021Pages 1743-1749

Intralesional corticosteroids (ILCs) is the first-line therapy for patients older than 10 years having patchy alopecia areata, however some patients do not respond effectively.

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Evaluation of treatment of acne scars with 25% trichloroacetic acid chemical peel followed by manual dermasanding

Hayder R. Al-Hamamy MBChB, DDV, CABD, PhD, Muhsin A. AL-Dhalimi MBChB, DDV, CABD, FICMS, Azhar F. Abtan MBChB, FICMS

doi : 10.1111/jocd.13754

Volume20, Issue6June 2021Pages 1750-1755

Acne scars are common problems encountered in daily dermatologic practice.

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Administration of skin care regimens containing ?-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study

Yajing Cao MD, Peiru Wang MD, Guolong Zhang MD, Chan Hu MD, Haiyan Zhang MD, Xiuli Wang MD, PhD

doi : 10.1111/jocd.13798

Volume20, Issue6June 2021Pages 1756-1762

Laser therapies have brought dawn to refractory skin diseases, but also were accompanied by postlaser inflammation and skin barrier dysfunction. To recover skin function quickly, the research and development of active ingredients including ?-glucan for postlaser repair have attracted much attention.

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“Comparison of QR 678® & QR678® Neo as monotherapy and as combination therapy with 5% Minoxidil solution and oral Finasteride in the treatment of male androgenetic alopecia—Which is better?”

Debraj Shome MD, FRCS, FACS, FAACS, MBA, Rinky Kapoor MD, Komal Doshi MDS, Ghanshyam Patel PhD, Sapna Vadera MDS, Vaibhav Kumar MDS

doi : 10.1111/jocd.14154

Volume20, Issue6June 2021Pages 1763-1765

no abstract

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Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris

Valeria Campos Dermatologist, MD at Universidade de S?o Paulo (USP), Luiza Pitassi Dermatologist, MD, PhD at Universidade Estadual de Campinas (UNICAMP), Célia Kalil Dermatologist, PhD at Universidade Federal do Rio Grande do Sul (UFRGS), José Euzébio Gonçalves J?nior Bachelor in Pharmacy at Universidade Federal do Rio de Janeiro (UFRJ), Beatriz Sant’Anna MD at (Universidade Federal do Rio de Janeiro (UFRJ), Priscila Correia Bachelor in Pharmacy at Universidade Federal Fluminense (USP)

doi : 10.1111/jocd.14016

Volume20, Issue6June 2021Pages 1766-1773

Acne is a chronic disease that affects the pilosebaceous follicle and is characterized by the presence of non-inflammatory and/or inflammatory lesions, affecting both adolescents and adults. Inflammatory acne lesions are capable to increase their melanin production and promote a post-inflammatory hyperchromia.

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Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy

Young In Lee MD, Soomin Kim PhD, Jihee Kim MD, Jemin Kim MD, Kyung Bae Chung MD, Ju Hee Lee MD, PhD

doi : 10.1111/jocd.13767

Volume20, Issue6June 2021Pages 1774-1781

Recent advancements in laser-assisted drug delivery have emphasized the importance of post-laser use of active ingredients.

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Serum level of interleukin-22 in patients with cutaneous warts: A case-control study

Radwa El-Sayed Mahmoud Marie MD, Aya Qamar Eldawla Mahmoud Abuzeid MD, Fadia M. Attia MD, Maha Mohamed Anani MD, Amal H. A. Gomaa MD, Lina M. Atef MD

doi : 10.1111/jocd.13779

Volume20, Issue6June 2021Pages 1782-1787

Warts are viral cutaneous infections caused by human papilloma virus (HPV), presented by verrucous growth over the skin surface. The immune response is considered to play a crucial role in HPV clearance.

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Demonstration of the dangerous nature of ‘homemade’ sunscreen recipes

Céline Couteau PhD, Coraline Dupont PharmD, Eva Paparis BHlthSci, Laurence J. M. Coiffard PhD

doi : 10.1111/jocd.13783

Volume20, Issue6June 2021Pages 1788-1794

Following a growing mistrust in a certain number of ingredients used by the cosmetic industry, it has become popular in recent years for consumers to make their own products at home.

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A double-blind, placebo-controlled randomized trial of skin-lightening cream containing lycopene and wheat bran extract on melasma

Neda Bavarsad PharmD, PhD, Mohammad Ali Mapar MD, Mona Safaezadeh PharmD, Seyed Mahmoud Latifi PhD

doi : 10.1111/jocd.13799

Volume20, Issue6June 2021Pages 1795-1800

Melasma is an acquired hyperpigmentation disorder, and reactive oxygen species play important role in regulating melanin synthesis. Lycopene is one of the most effective oxygen neutralizers among tomato-derived carotenoids.

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Topical ?-blockers for pyogenic granulomas: A promising option for younger patients

Abd El-Aziz Ibrahim El-Taweel MD, Abdul-Aziz Abdul-Salam Ahmed Al-Refaie MD, Khalid Hamdy Awad Salem MBBcH, Rehab Mohammed Salem MD

doi : 10.1111/jocd.13800

Volume20, Issue6June 2021Pages 1801-1806

Topical ?-blockers, propranolol, and timolol were used for pyogenic granuloma (PG) treatment; however, their efficacies and safety profiles were not compared.

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Efficacy of systemic minoxidil and tofacitinib combination in treatment-resistant alopecia universalis

Didem Dincer, Efsun Tanacan, Cansel Kose Ozkan

doi : 10.1111/jocd.13812

Volume20, Issue6June 2021Pages 1807-1809

Alopecia areata (AA) is an autoimmune nonscarring alopecic disorder, which presents with varying amounts of hair loss, ranging from focal patchy loss to entire scalp and body hair loss.

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Treatment of malar mound and festoon with fractional microneedle bipolar radiofrequency combined with 15% TCA peel

Zoran ?galjardi? MD, PhD, Ivonne ?galjardi? MD, Filip Juri? MD

doi : 10.1111/jocd.13740

Volume20, Issue6June 2021Pages 1810-1812

Anatomy of the periorbital region is very complex. Malar oedema/mounds/festoons often remain unaddressed. There are various treatments proposed for this pathologic entity as well as non-standardized nomenclature. Implementation of technology in aesthetic medicine and surgery resulted in novel treatments for this entity.

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Acral lentiginous melanoma: A retrospective study

doi : 10.1111/jocd.13737

Volume20, Issue6June 2021Pages 1813-1820

Acral lentiginous melanoma (ALM) carries one of the worst prognoses among other subtypes. This malignant tumor is found on the distal limbs and is usually detected at late stages. Hereby, the authors present their experience on this melanoma subtype.

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Vertical or horizontal scalp mobility: What to assess

doi : 10.1111/jocd.13738

Volume20, Issue6June 2021Pages 1821-1826

Scalp is comprised of five layers namely skin, connective tissue, aponeurosis, loose areolar tissue, and periosteum, each having distinct characteristics. The scalp mobility plays an important role in scalp wound closure. Thus, the estimation of scalp mobility is necessary to obtain a tension-free closure and fine scar in hair restoration surgery.

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Trichoscopy as an evaluation method for alopecia areata treatment: A comparative study

doi : 10.1111/jocd.13739

Volume20, Issue6June 2021Pages 1827-1836

Trichoscopy is a useful tool for diagnosis and follow-up of alopecia areata (AA) patients. Both platelet-rich plasma (PRP) and intralesional corticosteroids (ILCs) are important treatment modalities of patchy AA.

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“WAY”: A practical means to identify and treat the aging process

doi : 10.1111/jocd.13782

Volume20, Issue6June 2021Pages 1837-1845

Many patients consult a specialist in esthetics to improve certain aspects of their face that are altered by aging. To ensure optimal results and to define the best approach for such interventions, it is important that specialists have a comprehensive understanding of facial anatomy and of the aging process in the regions of interest.

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Preseptal cellulitis associated with cosmetic eyelash lifting procedure

doi : 10.1111/jocd.14142

Volume20, Issue6June 2021Pages 1846-1848

The increased popularity of periocular cosmetic applications in recent years has resulted in the appearance of various complications. The cosmetic eyelash lifting is one of these new techniques and is gradually becoming more popular. There are no previous reports of any complications of this procedure in the literature.

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An evaluation of the FDA adverse event reporting system and the potential for reporting bias

doi : 10.1111/jocd.14065

Volume20, IssueJune 2021Pages 1849-1854

The FDA maintains the Adverse Event Reporting System (CAERS) database, which contains product complaint reports for foods, dietary supplements, and cosmetics. Product line perception and subsequent adverse event reporting may be impacted by negative media attention.

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Examination of androgenetic alopecia with serum biomarkers

doi : 10.1111/jocd.13732

Volume20, Issue6June 2021Pages 1855-1859

Androgenetic alopecia (AGA) is the most common type of hair loss and affects approximately 50% of the male population.

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Epidemiological and biochemical factors (serum ferritin and vitamin D) associated with premature hair graying in Egyptian population

doi : 10.1111/jocd.13747

Volume20, Issue6June 2021Pages 1860-1866

The etiology of premature hair graying (PHG) remains incompletely understood with limited treatment options, although has profound impacts on patient’s quality of life.

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Effectiveness of growth factor-induced therapy for skin rejuvenation: A case series

doi : 10.1111/jocd.13750

Volume20, Issue6June 2021Pages 1867-1874

Microneedling in combination with the use of growth factors can help with a range of indications, including skin rejuvenation. There is an increase in request for safe minimally invasive procedures with no-to-minimal downtime. This procedure offers regeneration and is becoming popular as part of the regenerative, minimally invasive era.

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Predicting miRNA-lncRNA-mRNA network in ultraviolet A-induced human skin photoaging

doi : 10.1111/jocd.13760

Volume20, Issue6June 2021Pages 1875-1884

Recent researches had reported that microRNAs (miRNAs) played a role in skin photoaging. Our previous study found that long noncoding RNA (lncRNA) expression was changed in the UVA-irradiated skin fibroblasts, but the regulating network of noncoding RNA in UV-induced skin changes has not been elucidated well. Here, we investigated the interactions of miRNA-lncRNA-mRNAs in skin photoaging mechanisms.

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Prevention of scar hyperplasia in the skin by conotoxin: A prospective review

doi : 10.1111/jocd.13761

Volume20, Issue6June 2021Pages 1885-1888

Scars are often considered to be skin problems that affect beauty. The tension acting on the edge of the wound is the main factor causing the scar hyperplasia. At present, the clinical use of botulinum toxin A (BTX-A) around the wound to cause transient muscle paralysis reduce the muscle movement around the wound and wound tension to prevent scar hyperplasia during wound healing.

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Rosacea in acne vulgaris patients: Subtype distribution and triggers assessment—A cross-sectional study

doi : 10.1111/jocd.13762

Volume20, Issue6June 2021Pages 1889-1896

Recent studies have reported that the incidence of acne combined with rosacea is increasing. However, the clinical feature and inducing factor of these two diseases co-occurrence is remain unclear.

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Successful treatment of delayed pressure urticaria with 300 mg of omalizumab every 14 days

doi : 10.1111/jocd.13764

Volume20, Issue6June 2021Pages 1897-1899

Delayed pressure urticaria is a rare form of chronic inducible urticaria characterized by erythematous-painful plaques that develop in areas of the skin exposed to prolonged pressure. Its treatment is very difficult, and its response to antihistamines is variable. Cases of delayed pressure urticaria, which have been completely controlled with the use of omalizumab in recent years, have been reported.

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Efficacy of topical vs combined oral and topical antifungals in white piedra of the scalp

doi : 10.1111/jocd.13769

Volume20, Issue6June 2021Pages 1900-1905

Topical antifungals are the most commonly used therapy in white piedra of the scalp. However, persistence and relapse of infection still pose a significant challenge. Systemic antifungals have been recommended to enhance the therapeutic response.

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Genetic polymorphism of liver X receptor gene in vitiligo: Does it have an association?

doi : 10.1111/jocd.13772

Volume20, Issue6June 2021Pages 1906-1914

Vitiligo is an acquired depigmentation of the skin and the mucous membranes, exhibited as white macules and patches due to selective loss of melanocytes. Etiological theories of vitiligo include genetic, immunological, neurohormonal, cytotoxic, biochemical, oxidative stress, and newer theories of melanocytorrhagy and diminished melanocytes survival. It has been revealed that liver X receptor alpha gene is expressed in skin tissue such as sebaceous glands, hair follicle, keratinocytes, and fibroblasts and is linked to various skin disorders as acne vulgaris and psoriasis.

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Rubbing the skin when removing makeup cosmetics is a major factor that worsens skin conditions in atopic dermatitis patients

doi : 10.1111/jocd.13777

Volume20, Issue6June 2021Pages 1915-1922

Many patients with atopic dermatitis (AD) know that harsh rubbing of their skin might worsen their skin symptoms. They consider that the force they use to rub their skin when removing their makeup cosmetics should not be hard and their cleansing habits could worsen their skin symptoms. However, we presume that the force they use to rub their skin may still be strong and might worsen their skin symptoms.

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Tasmannia lanceolata leaf extract alleviates stretch mark appearance in a randomized, placebo-controlled clinical trial in women and stimulates extracellular matrix synthesis in ex vivo human skin explants

doi : 10.1111/jocd.13780

Volume20, Issue6June 2021Pages 1923-1932

The leaves of Tasmannia lanceolata mainly contain polygodial that is known to exhibit a range of biological functions including anti-inflammatory effects.

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Application of an in vitro reconstructed human skin on cosmetics in skin irritation tests

doi : 10.1111/jocd.13789

Volume20, Issue6June 2021Pages 1933-1941

At present, it is no longer possible to use animal testing for ingredients and cosmetic products in the Organisation for Economic Co-operation and Development (OECD) member states. However, in vitro tests are widely used to determine the safety and efficacy of ingredients and medicines.

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Scalp stencil: A new way to keep record

doi : 10.1111/jocd.13748

Volume20, Issue6June 2021Pages 1942-1943

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Acne inversa-like lesions and acneiform eruption associated with vemurafenib and cobimetinib used for advanced melanoma

doi : 10.1111/jocd.13758

Volume20, Issue6June 2021Pages 1944-1945

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Irritant contact dermatitis caused by zinc oxide eugenol and formocresol used in dental operation

doi : 10.1111/jocd.13778

Volume20, Issue6June 2021Pages 1946-1947

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Validation of the novel masseter muscle hypertrophy scale in Asian population

doi : 10.1111/jocd.13784

Volume20, Issue6June 2021Pages 1948-1950

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Letter to the editor regarding the article ‘‘Rossi A, Magri F, Michelini S, et al. New onset of alopecia areata in a patient with SARS-COV-2 infection: Possible pathogenetic correlations? J Cosmet Dermatol. 2021 Mar 19. doi: 10.1111/jocd.14080”

doi : 10.1111/jocd.14155

Volume20, Issue6June 2021Pages 1951-1952

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Corrigendum

doi : 10.1111/jocd.14107

Volume20, Issue6June 2021Pages 1953-1953

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Corrigendum

doi : 10.1111/jocd.14108

Volume20, Issue6June 2021Pages 1954-1954

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Retraction

doi : 10.1111/jocd.13859

Volume20, Issue6June 2021Pages 1955-1955

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