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Cover Image
Lei Xiao MS, Xia Zhang PhD, Zhiyi Chen MS, Bing Li PhD, Lin Li PhD
doi : 10.1111/jocd.13672
Volume 20, Issue 3 p. i-i
The cover image is based on the Original Contribution A Timosaponin B-II containing scalp care solution for improvement of scalp hydration on, dandruff reduction, and hair loss prevention: A comparative study on healthy volunteers before and after application by Lei Xiao et al.,
Cover Image
Yoonjin Lee MS, PhD, Kayoung Shin MS, Kyong-Oh Shin PhD, Seokjeong Yoon MS, Juyeon Jung MS, Eojin Hwang MS, Hwa-Jee Chung PhD, Amir M. Hossini PhD, Christos C. Zouboulis MD, PhD, Min Jeong Baek MS, Ji Hwoon Baek PhD, Young Min Chi MS, PhD, Sangeun Lee MD, PhD, Sekyoo Jeong PhD
doi : 10.1111/jocd.13952
Volume 20, Issue 3 p. ii-ii
The cover image is based on the Original Article The Effect of High-Intensity Focused Electromagnetic Procedure on Visceral Adipose Tissue: Retrospective Assessment of Computed Tomography Scans David Kent and Brian Kinney
Cover Image
David E. Kent MD, Brian M. Kinney MD, FACS, MSME
doi : 10.1111/jocd.13636
Volume 20, Issue 3 p. iii-iii
The cover image is based on the Original Contribution Topical application of autophagy-activating peptide improved skin barrier function and reduced acne symptoms in acne-prone skin by Yoonjin Lee et al.,
JCD Editorial—March 2021
Michael H. Gold MD
doi : 10.1111/jocd.13957
Volume 20, Issue 3 p. 709-710
No abstract
Aesthetic medicine during COVID-19: Patient perspectives and motivations amidst a pandemic
Angela Burleigh MD, PhD, Katie Beleznay MD, FRCPC, FAAD, Shannon Humphrey MD, FRCPC, FAAD
doi : 10.1111/jocd.13925
Volume 20, Issue 3 p. 711-713
No abstract
Blue Light Protection, Part I—Effects of blue light on the skin
Jahnna G. Coats, Briana Maktabi, Mariam S. Abou-Dahech, Gabriella Baki
doi : 10.1111/jocd.13837
Volume 20, Issue 3 p. 714-717
Blue light is emitted visible light between the wavelengths of 400 to 500 nm. The main source of blue light is sunlight, but digital screens, light-emitting diodes (LEDs), and fluorescent lighting serve as additional sources. Concerns about the negative effects of blue light on the skin have rapidly increased over the past 15 years, and consequently, the urge to learn more about this topic is increasing as well.
Blue light protection, part II—Ingredients and performance testing methods
Jahnna G. Coats BSPS, Briana Maktabi BSPS, Mariam S. Abou-Dahech BSPS, Gabriella Baki PhD
doi : 10.1111/jocd.13854
Volume 20, Issue 3 p. 718-723
There are numerous cosmetic ingredients that have been identified to have blue light protection benefits. The urge to learn more about blue light protection claims has led to several substantiation test methods that can be utilized by companies to prove product efficacy.
Do you know how to recommend a wig to your patient?
Fl?via Weffort MD, Sofia Sales Martins MD, Glaura Tinoco Plata MD, Cibele Tamietti Duraes MD, Daniel Fernandes Melo MSc, MD
doi : 10.1111/jocd.13602
Volume 20, Issue 3 p. 724-728
Throughout history, wigs have often had a relevant cultural and social importance with correlations to wealth and position of power. Wigs help minimize the psychological consequences of different types of hair loss.
In vivo SPF from multifunctional sunscreen systems developed with natural compounds—A review
Ana Luc?a Morocho-J?come RPh, PhD, Thamires Batello Freire MSc, Andressa Costa de Oliveira RPh, Tânia Santos de Almeida PhD, Catarina Rosado PhD, Maria Valéria Robles Velasco PhD, André Rolim Baby PhD
doi : 10.1111/jocd.13609
Volume 20, Issue 3 p. 729-737
The use of sunscreens is mandatory, especially in countries with high ultraviolet (UV) incidence. In consequence, there has been a growing interest in using compounds from natural sources to develop new multifunctional products that protect human skin from the consequences of UV exposition.
Seven strategies for the management of depigmented skin according to the etiopathogenesis
Sherif S. Awad MD, PhD
doi : 10.1111/jocd.13631
Volume 20, Issue 3 p. 738-745
Depigmented skin provides a considerable burden on the patient's daily life, and its management is a common challenge for dermatologists.
Noninvasive skin imaging in esthetic medicine—Why do we need useful tools for evaluation of the esthetic procedures
Klaudia Dopytalska MD, Piotr Sobolewski MD, Agata Mikucka-Wituszy?ska MD, Maciej Gnatowski MD, El?bieta Szyma?ska MD, PhD, Irena Walecka MD, PhD
doi : 10.1111/jocd.13685
Volume 20, Issue 3 p. 746-754
Despite the constant development of aesthetic medicine, there is still a lack of objective methods to assess the effectiveness of antiaging treatments and their impact on the skin.
Severe hyperalgesia and pain during botulinum toxin injection avoiding application in a patient 1 week after COVID-19 infection
Neslihan Akdogan MD
doi : 10.1111/jocd.13897
Volume 20, Issue 3 p. 755-756
No abstract
The effect of high-intensity focused electromagnetic procedure on visceral adipose tissue: Retrospective assessment of computed tomography scans
David E. Kent MD, Brian M. Kinney MD, FACS, MSME
doi : 10.1111/jocd.13952
Volume 20, Issue 3 p. 757-762
High levels of visceral adipose tissue (VAT) are associated with abdominal obesity and increased risk of metabolic deterioration. Recent studies showed that intensive physical exercise results in the reduction of subcutaneous and visceral fat.
Fractional CO2 laser versus trichloroacetic acid 50% for xanthelasma palpebrarum therapy
Nissreen Al-Sayed Al-Kady MSc, Mervat Hamdino MD, Faten Abdel wadoud Abdel Kawy MD
doi : 10.1111/jocd.13666
Volume 20, Issue 3 p. 763-768
Although being a benign lesion, xanthelasma palpebrarum (XP) causes cosmetic concerns. There are numerous therapeutic methods for XP with adverse events for each method.
Efficacy of the combination of Q-switched Nd:YAG laser and microneedling for melasma
?zlem Karada? K?se MD, Murat Borlu MD
doi : 10.1111/jocd.13629
Volume 20, Issue 3 p. 769-775
Melasma is a common, multifactorial, and recurring disease which is not easy to treat.
Effect of glycolic acid, phytic acid, soothing complex containing Emulsion on Hyperpigmentation and skin luminosity: A clinical evaluation
Elizabeth Bahar Houshmand MD, FAAD
doi : 10.1111/jocd.13950
Volume 20, Issue 3 p. 776-780
Improvement in skin luminosity and dyschromia such as postinflammatory hyperpigmentation (PIH) and actinic photodamage are leading causes for cosmetic consultation. Formulation of topical at home treatment is challenging, using a range of modalities, to help hinder or prevent inflammatory mediators without further irritating the skin.
Induction of allergic contact dermatitis and pervasive face edema due to Brazilian keratin treatment
Ebru Celik MD, Kubra Esin Korkmaz MD, Asena Cigdem Dogramaci MD
doi : 10.1111/jocd.13605
Volume 20, Issue 3 p. 781-783
Brazilian keratin treatment (BKT) is a prevalent hair straightening method widely used by women in the world. The degree of concentration of formaldehyde safe for sensitive patients is still obscure. Report claims that these products contain intolerably high levels of formaldehyde.
Topical odorant application of the specific olfactory receptor OR2AT4 agonist, Sandalore®, improves telogen effluvium-associated parameters
Francisco Jimenez MD, Esmeralda L?pez MD, Marta Bertolini PhD, Majid Alam PhD, Jérémy Chéret PhD, Gill Westgate PhD, Fabio Rinaldi MD, Barbara Marzani PhD, Ralf Paus MD
doi : 10.1111/jocd.13608
Volume 20, Issue 3 p. 784-791
Human hair follicles (HFs) express the olfactory receptor (OR)2AT4, which is selectively stimulated by the synthetic sandalwood-like odorant, Sandalore®. In organ-cultured, human scalp HFs, Sandalore® prolongs anagen and suppresses apoptosis by up-regulating intrafollicular IGF-1 mediated signaling.
An herbal cream reduces erythema of sensitive skin
Yuanjin Zhang MS, Yumei Jin MS, Philippe Humbert MD, PhD, Xiaoqing Fan MS, Yusi Cha MS, Yanni Guo MD, Li He MD, PhD
doi : 10.1111/jocd.13610
Volume 20, Issue 3 p. 792-797
Sensitive skin manifests itself as a syndrome defined by the occurrence of unpleasant sensations such as stinging, burning, and pruritus. Though not life-threatening, it can negatively impact the quality of people's lives because of symptoms and clinical signs. Although some skin care products can alleviate symptoms of sensitive skin, a product that can improve multiple abnormalities of sensitive skin are largely unavailable.
Hyaluronic acid-based two-stage medical therapy to unfold the aged face: The centrifugal approach
Carlo Di Gregorio MD, PhD, John Rogers MD, MPH, Salvatore D’Arpa MD, PhD
doi : 10.1111/jocd.13623
Volume 20, Issue 3 p. 798-803
Facial aging is a multifactorial process characterized by structural changes to the dermis and ligaments, lipoatrophy in the fat pads and hypodermis, remodeling of the bony skeleton, change in muscle tonicity and tissue descent.
Cosmetovigilance in a tertiary care hospital: A prospective observational study
Serika Jyrwa M.Pahrm, Juny Sebastian PhD, Veeranna Shastry MD
doi : 10.1111/jocd.13646
Volume 20, Issue 3 p. 804-811
Cosmetovigilance is a term used for the activities related to the collection, evaluation, and monitoring of reporting of undesirable events observed during or after normal or reasonably foreseeable use of a cosmetic product.
Clinical outcomes of topical bimatoprost for nonsegmental facial vitiligo: A preliminary study
Silada Kanokrungsee MD, Duangrat Pruettivorawongse MD, Msc, Natta Rajatanavin MD
doi : 10.1111/jocd.13648
Volume 20, Issue 3 p. 812-818
Vitiligo is a common acquired pigmentary disorder. Bimatoprost ophthalmic solution was indicated in the treatment of open-angle glaucoma and eyebrow hypotrichosis. However, lid hyperpigmentation was reported as a complication.
A Timosaponin B-II containing scalp care solution for improvement of scalp hydration, dandruff reduction, and hair loss prevention: A comparative study on healthy volunteers before and after application
Lei Xiao MS, Xia Zhang PhD, Zhiyi Chen MS, Bing Li PhD, Lin Li PhD
doi : 10.1111/jocd.13672
Volume 20, Issue 3 p. 819-824
The plant species Anemarrhena asphodeloides has commonly been used for health and therapeutic purposes. Timosaponin B-II, which is present at a high concentration in A asphodeloides, was found to enhance the immune and anti-inflammatory responses of human bodies.
A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity
Malkanthi Evans DVM, PhD, Erin D. Lewis PhD, Nisrine Zakaria PhD, Tetyana Pelipyagina MD, Najla Guthrie BSc
doi : 10.1111/jocd.13676
Volume 20, Issue 3 p. 825-834
Collagen is the primary component in human skin. With age, there is loss of skin elasticity and collagen, resulting in wrinkle formation and reduction in skin appearance.
Premature or nevoid sebaceous hyperplasia? Two case reports of a rare disease
Murat Ozturk MD, Erhan Ayhan MD, Isa An MD, MD, Zehra Akman Ilik MD, ?eyhmus Kaya MD
doi : 10.1111/jocd.13906
Volume 20, Issue 3 p. 835-837
Early or familial cases of sebaceous hyperplasia (SH) with multiple lesions, thought to be associated with genetic predisposition, have been reported in young individuals. Rarely reported variants include the giant, diffuse, zosteriform, and/or linear (nevoid) form. However, premature SH, defined as benign proliferation of sebaceous glands that occurs during or after puberty, is histologically similar to SH.
A topical naltrexone formulation for surgical wound healing: A case report
Jack Dunn RPh, Yi Liu PharmD, PhD, Fabiana Banov RPh, MS, Sebastian Denison RPh, Daniel Banov RPh, MS
doi : 10.1111/jocd.13604
Volume 20, Issue 3 p. 838-841
In current guidelines, there is no specific therapeutic recommendation for promoting surgical wound healing. Proper postsurgical wound care regimen can speed up wound healing and prevent abnormal scarring.
Evaluating the respective weights of some facial signs on perceived ages in differently aged women of five ethnic origins
Frederic Flament PhD, Aurelie Abric Bsc, Anne-Sophie Adam Bsc
doi : 10.1111/jocd.13612
Volume 20, Issue 3 p. 842-853
New gratification assessments, after skincare routines or makeup products, could benefit from innovative methods that could predict the culturally based perceptions of age.
Long-term stability of a novel platelet-rich plasma–based topical serum for cutaneous applications
Eduardo Anitua MD, DDS, PhD, Ander Pino PhD, Mar Zalduendo PhD
doi : 10.1111/jocd.13617
Volume 20, Issue 3 p. 854-861
Skin alterations are usually related to chronic diseases that demand sustained and long-term dosages; hence, it is pivotal that the stability of treatments is preserved. A novel storable and endogenous topical serum (ES) based on the patient's own blood has been recently developed.
Efficacy and safety of intralesional steroid injection in the treatment of melasma
Amany Abd Elrahman Nassar MD, Al-shimaa M. Ibrahim MD, Asmaa Atef Mahmoud MB, BCH
doi : 10.1111/jocd.13628
Volume 20, Issue 3 p. 862-867
The etiopathogenesis of melasma is not yet completely elucidated; however, certain inflammatory cytokines are involved in its pathogenesis as interleukin (IL) 1a, IL 1b, IL6, prostaglandin (PG) D2and PGE2. Corticosteroid suppressive effect on these cytokines may explain its therapeutic effect in the treatment of melasma.
Comparative study of intralesional tuberculin protein purified derivative (PPD) and intralesional measles, mumps, rubella (MMR) vaccine for multiple resistant warts
Yaser F. Mohammed MD, Hany S. Ibrahim MD, Marwa A. Elbarbary MD, Mohamed L. Elsaie MD
doi : 10.1111/jocd.13634
Volume 20, Issue 3 p. 868-874
To evaluate safety and efficacy of intralesional injection of tuberculin purified protein derivative (PPD) antigen injection vs MMR (mumps, measles, rubella) antigen for the treatment of multiple warts.
Instrumental diagnosis of facial skin—A necessity or a pretreatment recommendation in esthetic medicine
Weronika Kawa?kiewicz MSc, Maja Matthews-Kozanecka PhD, Marta Janus-Kubiak MSc, Leszek Kubisz PhD, Dorota Hojan-Jezierska PhD
doi : 10.1111/jocd.13638
Volume 20, Issue 3 p. 875-883
This paper presents the possibilities of pretreatment instrumental diagnosis for assessing the condition of various facial skin areas.
Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles
Cheng-Qian Yu MD, Xue-Gang Xu PhD, Hong-Duo Chen PhD, Yuan-Hong Li PhD
doi : 10.1111/jocd.13641
Volume 20, Issue 3 p. 884-889
Infraorbital dark circles (DC) are defined as a symptom that presents darkness under infraorbital eyelids. The objective of this study was to evaluate the efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol (PR) for the treatment of infraorbital dark circles.
Characterization and classification of different female hairline patterns in the Thai population
Wasrin Natpracha MD, Siriorn Sukanjanapong MD, MSc, Kumutnart Chanprapaph MD, MSc, Poonkiat Suchonwanit MD
doi : 10.1111/jocd.13642
Volume 20, Issue 3 p. 890-896
The hairline is an essential component of the human face. Disfigurement of the hairline may cause physical and psychological problems. Standard guidelines do not exist for female hairline designs, average values of infratemporal portion, hairline classifications, and preferences.
Skin barrier damaging and repairing process: A new application field of dermoscopy
CongXiu Ye MD, JinLing Yi MD, Wei Lai MD, Yue Zheng PhD
doi : 10.1111/jocd.13643
Volume 20, Issue 3 p. 897-905
Although more and more noninvasive detection technologies have been used in assessing skin barrier integrity and functions, more accurate, intuitive, and convenient detective methods still needed to be explored and developed.
Prevention of impending scalp necrosis by topical nitroglycerine in hair transplant surgery
Zaheer Abbas MD, Hamid Kufi MD
doi : 10.1111/jocd.13659
Volume 20, Issue 3 p. 906-910
Recipient site necrosis is a rare but potentially devastating complication of hair restoration surgery. Appropriate case selection and procedure performed by expert surgical team are although mandatory but not enough to prevent such event, particularly in megasessions. Timely recognition of impending necrosis is very important to consider preventive measures.
Modified double-eyelid blepharoplasty with the combined partial- And minimal-incision method
Xiao Shen MD
doi : 10.1111/jocd.13660
Volume 20, Issue 3 p. 911-916
Double-eyelid surgery remains a popular esthetic surgery in East Asian people. The partial-incision method provides the benefits of full-incision and nonincision techniques. It can create a predictable and durable double-eyelid crease.
The effect of hyperbaric oxygen therapy combined with hair transplantation surgery for the treatment of alopecia
Zhe-Xiang Fan MD, PHD, Yuyang Gan MD, Qian Qu MD, PHD, Jin Wang MD, PHD, Yang Lunan MD, PHD, Bingcheng Liu MD, PHD, Ruosi Chen MD, PHD, Zhi-Qi Hu MD, PhD, Yong Miao MD, PhD
doi : 10.1111/jocd.13665
Volume 20, Issue 3 p. 917-921
Transplanted hair follicles suffer from various injuries, which are difficult to prevent. Hyperbaric oxygen therapy (HBOT) was reported to be an excellent procedure to promote capillary regeneration and reduce ischemia-reperfusion injury.
Consensus report on the use of PN-HPT™ (polynucleotides highly purified technology) in aesthetic medicine
Maurizio Cavallini MD, Emanuele Bartoletti MD, Laura Maioli MD, Alberto Massirone MD, Isabella Pia Palmieri MD, Marco Papagni MD, Maurizio Priori MD, Gloria Trocchi MD, As Members of The Polynucleotides HPT™ Priming Board, Collegio Italiano delle Società Scientifiche di Medicina Estetica (Italian College of the Aesthetic Medicine Scientific Societies) — SIME, AGOR?, SIES
doi : 10.1111/jocd.13679
Volume 20, Issue 3 p. 922-928
Injective procedures using polynucleotides-based products to promote dermal rejuvenation and revitalization are steadily evolving, yet no structured protocols are available that discuss and provide guidance in aesthetic treatments with highly purified polynucleotides. The goal of this document was to provide consensus-based recommendations for the safe and effective use of Polynucleotides Highly Purified Technology™ (PN-HPT™) devices for skin rejuvenation.
The shifting preferences of patients and physicians in nonsurgical hair loss treatment
Aditya K. Gupta MD, PhD, Emma M. Quinlan BA, BSc, Ken L. Williams DO
doi : 10.1111/jocd.13681
Volume 20, Issue 3 p. 929-936
There are multiple etiologies for hair thinning and loss, including genetic, hormonal, immune, scaring, and infectious. Hair loss treatment involves both surgical intervention and nonsurgical therapies such as pharmaceuticals, haircare products, vitamins, and low-level laser therapy (LLLT).
Keystone-designed perforator island flaps for reconstruction after chest keloid excision: A retrospective case series
Jiuzuo Huang MD, Ruijia Dong BSc, Xiaojun Wang MD, Nanze Yu MD, Ru Zhao MD, Ming Bai MD, Hailin Zhang MD, Yang Wang MD, Xiao Long MD
doi : 10.1111/jocd.13684
Volume 20, Issue 3 p. 937-942
We retrospectively evaluated the efficacy and safety of keystone-designed perforator island flaps for chest keloid reconstruction.
Pyoderma gangrenosum with thymoma and myasthenia gravis: A case report
Fatma Tunçez Akyürek MD, Mehmet Akyurek MD, Emre Zekey MD, Ismail Can MD, Gulcan Saylam Kurtipek MD
doi : 10.1111/jocd.13717
Volume 20, Issue 3 p. 943-946
Pyoderma gangrenosum (PG) is a rare, neutrophilic dermatosis which is characterized by painful, necrotic ulcer with violaceous border that heals with cribriform scar.
Lipidomics reveals the role of glycoceramide and phosphatidylethanolamine in infantile acne
Manli Yang, Mingyue Zhou, Hecong Wang, Ming Yang, Ying Gao, Yan Jia
doi : 10.1111/jocd.13823
Volume 20, Issue 3 p. 947-954
Infantile acne refers to a skin disease that usually occurs on the face from 6 weeks to 1 year old, and the etiology of infantile acne is different from that of puberty acne. The change of skin surface lipid (SSL) is an important factor in the occurrence of acne.
Study on the skin status of mid-pregnancy women based on lipidomics
Feng Chen BS, Dianchao Huang MS
doi : 10.1111/jocd.13866
Volume 20, Issue 3 p. 955-963
Pregnancy is a complex physiological state and its unique changes in skin state have been discussed. Skin surface lipid (SSL) is an important molecular basis for this skin condition, and it affects skin condition in a number of ways, but there are no complete research data on it.
Role of KLF2: New insight in inflammatory acne pathogenesis
Menha A. Ibrahim MD, Shuzan Ali Mohammed MD, Doaa M. Elhabak MD
doi : 10.1111/jocd.13595
Volume 20, Issue 3 p. 964-970
Acne is an inflammatory skin condition of pilosebaceous unit. Its pathogenesis is multifactorial with a central role of inflammatory and pro-inflammatory cytokines mediators. Downregulated Kruppel-like factor 2 (KLF2) leads to rapid secretion of many cytokines that are involved in acne pathogenesis.
Correlation between serum granulysin level and clinical activity in patients with alopecia areata before and after tofacitinib therapy
Muazzez Cigdem Oba MD, Ozge Askin MD, Ozlem Balci Ekmekci PhD, Server Serdaroglu MD
doi : 10.1111/jocd.13598
Volume 20, Issue 3 p. 971-975
Alopecia areata (AA) is a common immune-mediated disorder. Destruction of anagen hair follicles by cytotoxic T cells (CTL) plays a major role in the pathogenesis of AA. Serum granulysin has been shown to reflect overall activity of CTLs.
Co-localization of alopecia areata and lichen planopilaris in a patient receiving immunosuppressants: A rare case
Ramin Mofarrah MD, Ramina Mofarrah, Kousar Jahani Amiri, Maryam Ghasemi MD
doi : 10.1111/jocd.13600
Volume 20, Issue 3 p. 976-979
AA is an acquired dermatosis distributed universally, with multifactorial etiology.
Vitamin D receptor (VDR) gene polymorphism in Egyptian vitiligo patients
Wael M. Saudi MD, Mervat M. Swelam MD, Rasha A. H. El-Barbary MD, Lola Zakaria MSc, Dalia A. Gaber MD
doi : 10.1111/jocd.13606
Volume 20, Issue 3 p. 980-986
Vitiligo is an autoimmune dermatological disorder, precipitated by genetic and nongenetic factors leading to destruction of epidermal melanocytes. In Egypt, it has a prevalence rate of 1.2%.
Isobutylamido thiazolyl resorcinol for prevention of UVB-induced hyperpigmentation
Vasanop Vachiramon MD, Chaninan Kositkuljorn MD, Kanchana Leerunyakul MD, Kumutnart Chanprapaph MD
doi : 10.1111/jocd.13615
Volume 20, Issue 3 p. 987-992
Isobutylamido thiazolyl resorcinol (ITR, Thiamidol®) has been proposed as a potent tyrosinase inhibitor. A formulation containing ITR has recently shown promising efficacy for the treatment of some hyperpigmentary conditions.
In vitro evaluation of antioxidant and antibacterial activities of Eucheuma cottonii extract and its in vivo evaluation of the wound-healing activity in mice
Brian Sheng Xian Teo PhD, Rui Yi Gan BPharm, Sarah Abdul Aziz BPharm, Thanchanok Sirirak PhD, Mohd Fadli Mohd Asmani PhD, Eddy Yusuf PhD
doi : 10.1111/jocd.13624
Volume 20, Issue 3 p. 993-1001
Eucheuma Cottonii is a type of red algae obtained from Sabah with main active component, sulfated polysaccharide or k-carrageenan.
Biophysical characteristics of dandruff-affected scalp categorized on the basis of sebum levels
Ji-Seon Yoon PhD, Jiyong Shim MS, Jun-Man Lim MS, Sun Gyoo Park MS
doi : 10.1111/jocd.13626
Volume 20, Issue 3 p. 1002-1008
Various sebum levels can be detected in dandruff-affected scalps. However, few studies have compared the biophysical characteristics of dandruff scalps categorized based on sebum levels.
Topical application of autophagy-activating peptide improved skin barrier function and reduced acne symptoms in acne-prone skin
Yoonjin Lee MS, PhD, Kayoung Shin MS, Kyong-Oh Shin PhD, Seokjeong Yoon MS, Juyeon Jung MS, Eojin Hwang MS, Hwa-Jee Chung PhD, Amir M. Hossini PhD, Christos C. Zouboulis MD, PhD, Min Jeong Baek MS, Ji Hwoon Baek PhD, Young Min Chi MS, PhD, Sangeun Lee MD, PhD, Sekyoo Jeong PhD
doi : 10.1111/jocd.13636
Volume 20, Issue 3 p. 1009-1016
Recent studies about the important roles of autophagy signaling in sebaceous lipogenesis and epidermal differentiation suggest potential benefits of autophagy activation in acne.
Serum TWEAK: A cutoff between segmental and nonsegmental vitiligo
Abd El-Aziz Ibrahim El-Taweel MD, Amira Mohamed Noureldin Abdelrahman MD, Sarah Sabry MBBcH, Rehab Mohammed Salem MD
doi : 10.1111/jocd.13644
Volume 20, Issue 3 p. 1017-1021
TWEAK/Fn14 is expressed in many tissues including the skin, playing an important role in many inflammatory, autoimmune, and neoplastic cutaneous disorders.
Noninvasive evaluation of the influence of aucubin-containing cosmetic macroemulsion on selected skin parameters
Marta D?browska PhD, Izabela Nowak PhD, DSc
doi : 10.1111/jocd.13649
Volume 20, Issue 3 p. 1022-1030
Objective evaluation of skin condition on the basis of noninvasive methods has become obligatory and may be a good strategy for verifying the efficiency of new cosmetic active ingredients.
Measuring the serum level of retinol-binding protein can enhance the treatment of recalcitrant warts
Hesham N. Khalid MD, Eman M. Abd El Gayed MD, Rasha A. Dawoud MBBCh, Heba A. S. Bazid MD
doi : 10.1111/jocd.13683
Volume 20, Issue 3 p. 1031-1036
Warts are common benign (60%-65%) self-limited tumors of the epidermis caused by human papillomaviruses (HPVs). However, some warts fail to resolve despite of different treatments and become recalcitrant. Vitamin A has antiproliferative and antikeratinizing properties by which the disruption of HPV replication can be occurred. Concentrations of retinol-binding protein (RBP) and retinol in the circulation highly correlate with each others.
