Journal of Cosmetic Dermatology




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Cover Image

Alan D. Widgerow MBBCh, MMed, FCS, FACS, Karl Napekoski MD

doi : 10.1111/jocd.13942

Volume 20, Issue 2 p. i-i

The cover image is based on the Original Contribution New approaches to skin photodamage histology—Differentiating 'good' versus 'bad' Elastin by Alan D. Widgerow and Karl Napekoski

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Issue Information

doi : 10.1111/jocd.13923

Volume 20, Issue 2 p. 369-370

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JCD editorial—February 2021

Michael H. Gold MD

doi : 10.1111/jocd.13924

Volume 20, Issue 2 p. 371-371

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SARS-CoV-2 not found in pressure injury exudates from COVID-19 patients

Nanze Yu, Yuwei Zhang, Meng Xiao, Wei Cao, Yan Zhang, Yang Yang, Zhengyin Liu, Yunzhu Li, Xiao Long, Zhifei Liu, Shuyang Zhang MD, Xiaojun Wang MD

doi : 10.1111/jocd.13887

Volume 20, Issue 2 p. 372-380

The emergence of COVID-19 has become a global health emergency. The transmissibility of the disease is of great interest to healthcare workers and scientists alike.

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Benefits of fractional radiofrequency treatment in patients with atrophic acne scars - Literature review

Cristina Cucu, Alexandra-Irina Butacu, Bogdan-Dimitrie Niculae, George-Sorin Tiplica

doi : 10.1111/jocd.13900

Volume 20, Issue 2 p. 381-385

Acne scars carry a huge physical and psychological impact on people. This article aims to evaluate the role of fractional radiotherapy in treatment of atrophic acne scars. The main objective includes providing an up-to-date review of existing literature, presenting the most significant studies conducted in this field.

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Visualization techniques of the facial arteries

Marc Mespreuve MD, PhD, Karl Waked MD, Benoit Hendrickx MD, PhD

doi : 10.1111/jocd.13477

Volume 20, Issue 2 p. 386-390

As the face is known for its extreme variation in vascular anatomy and the number of filler-associated complications due to intra-arterial injection is increasing, we are in need of a method to visualize anyone’s individual arterial anatomy of the face in a completely harmless way.

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Review on perfume and present status of its associated allergens

Mohit Kumar B. Pharm, Arpna Devi B. Pharm, Maninder Sharma B. Pharm, Palakdeep Kaur M. Pharm, Uttam Kumar Mandal PhD

doi : 10.1111/jocd.13507

Volume 20, Issue 2 p. 391-399

Perfume is basically a cosmetic product applied to human body for an amusing scent or the feeling of freshness. A certain amount of perfume penetrates and remains attached to the protein of the skin when perfume is applied on the body.

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Potential role of the skin microbiota in Inflammatory skin diseases

Pan Chen MD, Guangwen He PhD, Jingru Qian MASc, Yi Zhan MD, Rong Xiao MD

doi : 10.1111/jocd.13538

Volume 20, Issue 2 p. 400-409

Inflammatory skin diseases include a variety of skin diseases, such as seborrheic dermatitis, acne, atopic dermatitis, psoriasis and so on, which are more common and tend to have a significant impact on patients' quality of life.

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Immunocompromised cutaneous district, isotopic, and isopathic phenomena—Systematic review

Gabriel V. B. S. Tabosa MSc, Rafael F. Stelini Msc, Elemir M. Souza PhD, Paulo E. N. F. Velho PhD, Maria L. Cintra PhD, Michelle E. B. Florence PhD

doi : 10.1111/jocd.13592

Volume 20, Issue 2 p. 410-416

Although the development of lesions in skin areas that have undergone injury has long been known, understanding of its pathogenesis is limited. Depending on their peculiarities, those events have been described as isomorphic, reverse isomorphic, pseudoisomorphic, isotopic, and isopathic phenomena. Ruocco's immunocompromised cutaneous district (ICD) concept was proposed to include all those phenomena.

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Ultrasound-guided poly-l-lactic acid nodule excision: The importance of the injector ultrasonographic experience

Bruna Souza Felix Bravo MD, Raquel de Melo Carvalho MD, Eduardo Souza MD, Thiago Jeunon De Souza Vargas MD, Leonardo Gonçalves Bravo MD

doi : 10.1111/jocd.13527

Volume 20, Issue 2 p. 417-419

The possibilities for facial and body treatments are wide, but when it comes to treatment for the cervical region, the options are more restricted and among them, the use of poly-l-lactic acid (PLLA) stands out.

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Primary facial demodicosis as a health problem and aesthetic challenge: A case report

Renata Przydatek-Tyrajska PhD Student, Aleksandra S?dzikowska PhD, Katarzyna Bartosik PhD Habilitated

doi : 10.1111/jocd.13542

Volume 20, Issue 2 p. 420-424

Colonization of skin by Demodex mites developing as a single facial lesion with a limited range is diagnosed relatively rarely. The presence of this type of skin lesions may hinder and thus delay the diagnostic process and application of appropriate treatment.

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Use of vibrating anesthetic device reduces the pain of mesotherapy injections: A randomized split-scalp study

Raquel de Melo Carvalho MD, Taynara de Mattos Barreto MD, Flavia Weffort MD, Carla Jorge Machado MA, PhD, Daniel Fernandes Melo MSc, MD

doi : 10.1111/jocd.13554

Volume 20, Issue 2 p. 425-428

Pain evaluation during local injections is a complex process. Injections cause patient's distress, especially when the target is a sensitive area such as scalp.

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Dermatologic management of oncotherapy side effects: A proposed algorithm

Marta Carlesimo MD, Flavia Pigliacelli MD, Andrea D’Arino MD, Gemma Caro MD, Maria Caterina Fortuna MD, Alfredo Rossi PhD

doi : 10.1111/jocd.13566

Volume 20, Issue 2 p. 429-436

Since the introduction of the first chemotherapeutic regimens for the treatment of oncological disease, hundreds of drugs have been approved for cancer treatment and many more are under investigation.

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Utility of platelet-rich plasma for treatment of striae distensae: A current exploration

Kerry Heitmiller MD, Jordan V. Wang MD, MBE, MBA, Robert D. Murgia DO, MA, Nazanin Saedi MD

doi : 10.1111/jocd.13567

Volume 20, Issue 2 p. 437-441

Platelet-rich plasma (PRP) has recently become a popular treatment for various skin conditions, including striae distensae, acne scars, traumatic scars, hair regrowth, and cutaneous rejuvenation.

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Single-center, prospective comparison of calcium hydroxylapatite and Vycross-20L in midface rejuvenation: Efficacy and patient-perceived value

Alan Durkin MD, Alexandra Lackey MD, Alyssa Tranchilla BS, Maxwell Poling PA-C, Gabriella Glassman MD, Nick Woltjen PA-C

doi : 10.1111/jocd.13881

Volume 20, Issue 2 p. 442-450

Numerous fillers can be used for midface revolumization. While rheological data, physiochemical properties, and durability measured in clinical studies can inform selection, direct comparisons between equal volumes of different fillers are lacking.

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Comparative analysis of botulinum toxin injection after corrective rhinoplasty for deviated nose and alar asymmetry

Won Lee MD, PhD, Tae-Hwan Ahn MD, PhD, Gwahn-Woo Cheon MD, MS, Min-Ji Lee MD, Eun-Jung Yang MD, PhD

doi : 10.1111/jocd.13523

Volume 20, Issue 2 p. 451-456

Deviated noses and asymmetric nostrils can be corrected using corrective rhinoplasty. However, after proper correction, adjacent facial mimetic muscles can cause recurrence of asymmetry because of preoperative habits.

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Mandibular osteomyelitis after hyaluronic acid injection

Hayson Chenyu Wang MD, PhD, Yunting Wang MD, Xiao Long MD, Xiaojun Wang MD, PhD

doi : 10.1111/jocd.13575

Volume 20, Issue 2 p. 457-459

Mandibular osteomyelitis after filler injection is extremely rare.

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Micro-needling versus fractional carbon dioxide laser for delivery of tranexamic acid in the treatment of melasma: A split-face study

Khaled M. M. Mekawy MSc, Ahmed Sadek MD, Ahmad K. Seddeik Abdel-Hameed MD

doi : 10.1111/jocd.13537

Volume 20, Issue 2 p. 460-465

Tranexamic acid (TXA) in oral, topical, and intra-dermal injection routes showed efficacy in melasma treatment. Micro-needling and fractional carbon dioxide (CO2) laser were reported to enhance the drug delivery of TXA.

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The efficacy of intense pulsed light for Becker's nevus: A retrospective analysis of 45 cases

Yiping Zhong MD, Lining Huang MD, Yongjun Chen MD, Tingting Yan MD, Bin Yang MD, Mao-Qiang Man MD

doi : 10.1111/jocd.13558

Volume 20, Issue 2 p. 466-471

Becker's nevus is a common skin disorder. Lasers and light instruments are the major modalities for the treatment of Becker's nevus, but the outcomes were mixed.

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Ablative fractional CO2 laser vs lyophilized growth factor intralesional injection vs combination of both modalities for striae distensae treatment

Mahmoud Abdallah MD, Hossam Fahmy MD, Shawkat Abdel Hameed MB, BCH, Azza E. Mostafa MD

doi : 10.1111/jocd.13564

Volume 20, Issue 2 p. 472-480

Different studies had evaluated the efficacy of fractional CO2 laser and platelet-rich plasma (PRP) in treating striae distensae (SD). Lyophilized growth factors (LGF) represent another form of delivering growth factors similar to PRP with a more standardized method. To the best of our knowledge, no previous trials have been reported using LGF in SD.

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Self-contrast study of pinprick therapy combined with super pulse fractional CO2 laser for the treatment of atrophic acne scars

Zhi Yang MD, Song Jiang MM, Yiqiong Zhang MM, Yuan Chen MM, Yaxin Tan MM, Hong Su MM, Ying Xiong MM, Qiongyan Li MD, Li He MD

doi : 10.1111/jocd.13568

Volume 20, Issue 2 p. 481-490

This study is to evaluate the clinical efficacy and safety of a “double-layer” mode of super pulse fractional CO2 laser and a combined treatment of pinprick therapy with fractional CO2 laser for the treatment of atrophic acne scars.

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Carbon dioxide ablative laser treatment of acquired junctional melanocytic nevi

Osman K?se MD

doi : 10.1111/jocd.13579

Volume 20, Issue 2 p. 491-496

Junctional melanocytic nevi are common. Furthermore, surgical treatment of these nevi can be challenging due to scar formation.

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Treatment of idiopathic onychodystrophy with a 1064 nm picosecond neodymium-doped:yttrium aluminum garnet laser: A retrospective study

Yun Ho Lee MD, Heun Joo Lee MD, Won-Serk Kim MD, PhD, Ga-Young Lee MD, PhD, Young-Jun Choi MD

doi : 10.1111/jocd.13580

Volume 20, Issue 2 p. 497-505

Laser treatment has emerged as a novel treatment modality for onychodystrophy. Only a few small series have assessed the efficacy of laser treatment in onychodystrophy, most of which were case reports. The therapeutic effect of the 1064 nm neodymium-doped:yttrium aluminum garnet (Nd:YAG) laser for onychodystrophy has been demonstrated.

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Wart removal without anesthesia using long-pulse 1064-nm Nd:YAG laser

An?e Zorman MD, Ne?a Koron PhD

doi : 10.1111/jocd.13593

Volume 20, Issue 2 p. 506-512

Warts are benign epithelial proliferations that result from human papillomavirus (HPV) infection occurring on the skin and mucosa. Patients express a significant reduction in quality of life due to this cosmetic nuisance, as well as functional problems and physical discomfort. Newer methods of wart removal include different energy-based devices, mostly lasers. Nonablative lasers such as Nd:YAG have a higher success rate and are usually used with topical or infiltrative anesthesia

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Glycolic acid adjusted to pH 4 stimulates collagen production and epidermal renewal without affecting levels of proinflammatory TNF-alpha in human skin explants

Mridvika Narda PhD, Carles Trullas MSc, Anthony Brown PhD, Jaime Piquero-Casals MD, PhD, Corinne Granger MD, MSc, Gabriella Fabbrocini MD

doi : 10.1111/jocd.13570

Volume 20, Issue 2 p. 513-521

Glycolic acid (GA) is an effective way of reversing the signs of age and photodamage. GA enhances desquamation of the stratum corneum and induces biological responses that can help restore skin's integrity. GA can, however, cause irritation, especially when its concentration is high, and its pH is low.

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Nature-based botanical facial oil oxidative stress protection

Zoe Diana Draelos MD, Hemali Gunt PhD, Stanley B. Levy MD

doi : 10.1111/jocd.13879

Volume 20, Issue 2 p. 522-525

UV-induced oxidative skin stress leads to cutaneous photoaging. The objective of these 2 studies was to evaluate a nature-based botanical facial oil for the ability to decrease UV-induced oxidative skin stress.

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New approaches to skin photodamage histology—Differentiating 'good' versus 'bad' Elastin

Alan D. Widgerow MBBCh, MMed, FCS, FACS, Karl Napekoski MD

doi : 10.1111/jocd.13865

Volume 20, Issue 2 p. 526-531

Photodamage creates changes within the skin layers known as solar elastosis. This presents as fragmentation of collagen and elastin fibers, decreases in the extracellular matrix (ECM) ground substance, as well as hyaluronic acid decrease in the thinning epidermis. Traditional immunohistochemistry (IHC) staining has failed to differentiate degenerated elastin from new elastin fibers generated with various topical strategies.

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Iron oxides in novel skin care formulations attenuate blue light for enhanced protection against skin damage

Eric F. Bernstein MD, MSE, Harry W. Sarkas PhD, Patricia Boland BA

doi : 10.1111/jocd.13803

Volume 20, Issue 2 p. 532-537

Ultraviolet (UV) radiation is a main cause of aging of sun-exposed skin, but greater attention is being focused on the damaging effects of high-energy visible (HEV) light (400 and 500 nm). HEV light exposure has increased with expanding use of consumer electronics, such as smartphones, which have a peak emission in the 400-490 nm range. Sunscreens containing titanium dioxide and zinc oxide protect against UVA and UVB radiation but provide limited protection against HEV light.

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Efficacy of topical antioxidants in the skin hyperpigmentation control: A clinical study by reflectance confocal microscopy

Gabriela Maria D'Angelo Costa MSc, Patr?cia Maria Berardo Gonçalves Maia Campos PhD

doi : 10.1111/jocd.13804

Volume 20, Issue 2 p. 538-545

Some in vitro studies have reported the potential of antioxidants for the reduction of melanogenesis. However, it is important to assess the clinical efficacy of these substances in reducing skin hyperpigmentation. Thus, the aim of this study was to evaluate the clinical efficacy of dermocosmetic formulations based on antioxidants using Reflectance confocal microscopy (RCM).

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Carboxytherapy for striae distensae: A promising modality

Moetaz El-Domyati MD, Wael Hosam El-Din MD, Walid Medhat MD, Michel R. Ibrahim MD, Yasmin khaled Msc

doi : 10.1111/jocd.13844

Volume 20, Issue 2 p. 546-553

Striae distensae (SD) is a very common skin problem. Although a lot of treatment modalities have been proposed, few of them are effective. Recently, carbon dioxide therapy (CDT) or carboxytherapy was used in many indications of cosmetic dermatology such as SD.

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Formulation and efficacy evaluation of the safe and efficient moisturizing snow mushroom hand sanitizer

Nattaya Lourith PhD, Sathaporn Pungprom MSc, Mayuree Kanlayavattanakul PhD

doi : 10.1111/jocd.13543

Volume 20, Issue 2 p. 554-560

Snow fungus or snow mushroom or white jelly mushroom (Tremella fuciformis), the edible mushroom, was formulated into hand sanitizer in form of moisturizing alcohol-based hand rub (ABHR) gel.

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New topical tranexamic acid derivative for the improvement of hyperpigmentation and inflammation in the sun-damaged skin

Ivan D. da Silva Souza PhD, Lorraine Lampe Bachelor of Chemistry, Daniel Winn PhD

doi : 10.1111/jocd.13545

Volume 20, Issue 2 p. 561-565

Skin-lightening products are used worldwide to treat persistent pigmentation disorders that impact our quality of life and self-confidence.

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Understanding aesthetic interest in oral collagen peptides: A 5-year national assessment

Christian A. Albornoz MD, Saloni Shah BS, Robert D. Murgia DO, MA, Jordan V. Wang MD, MBE, MBA, Nazanin Saedi MD

doi : 10.1111/jocd.13555

Volume 20, Issue 2 p. 566-568

Oral supplementation with collagen peptides has recently grown in popularity. It has been marketed to offer skin rejuvenating properties, such as wrinkle reduction, skin plumping, and moisturizing effects. However, current data are limited regarding its effects on the skin. Despite the controversial status of oral collagen supplements, its popularity has continued to rise. Here, we examine the consumer interest in oral collagen peptides over a 5-year period in the United States.

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The Aging neck—A Case base treatment algorithm

Or Friedman MD, Ava Shamban MD, Sabrina Fabi MD, Diane I. Duncan MD, Ofir Artzi MD

doi : 10.1111/jocd.13877

Volume 20, Issue 2 p. 569-576

Effective nonsurgical treatments for the aging face are widely accepted and utilized. Although changes in the aging neck, often patients to seek esthetic rejuvenation protocols are neither well defined nor well designed. Increasingly, patients desire less invasive cosmetic treatments with less morbidity and downtime.

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Hair loss treatment information on Facebook: Content analysis and comparison with other online sources

Aditya K. Gupta MD, PhD, Iordanka A. Ivanova PhD

doi : 10.1111/jocd.13830

Volume 20, Issue 2 p. 577-583

Facebook is the biggest online social networking platform, and it is being utilized by patients for peer support as well as to explore treatment options. Hair loss patients can experience negative psychological effects and are likely to turn to social networking platforms for support and treatment information.

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The first comprehensive classification of hair transection: A step forward

Muhammad Ahmad MD, ABHRS, Mohammad Humayun Mohmand MD, FISHRS

doi : 10.1111/jocd.13524

Volume 20, Issue 2 p. 584-587

There has been an increase in the hair transplant surgeries especially FUE all over the world during last two decades. The more the number of grafts being harvested result in increase in transection. Unfortunately, there is no classification dealing with the hair transection. The authors have proposed the first comprehensive classification for document different levels of hair transections.

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Favorable effects of microneedling on long-standing androgenetic alopecia in an elderly man: A case report

Jun Fujita MD, PhD

doi : 10.1111/jocd.13526

Volume 20, Issue 2 p. 588-590

Androgenetic alopecia (AGA) is the most common type of alopecia. Currently, various methods have been tried to treat male AGA, but the outcomes are often unsatisfactory, especially for elderly persons.

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Usefulness of home-use microneedle devices in the treatment of pattern hair loss

Chihyeon Sohng MD, Eun Hye Lee MD, Soo Kyeong Woo MD, Jun Young Kim MD, Kyung Duck Park MD, PhD, Seok-Jong Lee MD, PhD, Weon Ju Lee MD, PhD

doi : 10.1111/jocd.13540

Volume 20, Issue 2 p. 591-596

Microneedle devices have been used to reduce scarring and wrinkling as well as for the treatment of pattern hair loss.

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A noninvasive myorelaxant approach resulting in gummy smile improvement—A pilot study

Krzysztof Bojanowski PhD, Pedro Corona BS, Stephanie Ma BS, Hui Zhao MD, DMD

doi : 10.1111/jocd.13547

Volume 20, Issue 2 p. 597-601

The opportunity to shape facial appearance through noninvasive muscle relaxation procedures remains largely unfulfilled. Here, a hypothesis was tested whether an intraoral application of a mucoadhesive, biodegradable slow release formulation may trigger beneficial cosmetic outcomes in and around the mouth.

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Tattoo: Ancient art and current problems

Giulio Gualdi MD, Antonella Fabiano MD, Ruggero Moro MD, Anna Venturuzzo MD, Paola Monari MD, Piergiacomo Calzavara-Pinton MD, Paolo Amerio MD

doi : 10.1111/jocd.13548

Volume 20, Issue 2 p. 602-604

The popularity of tattoos in the today's society brings with it a significant increase of the incidence of associated cutaneous reactions. Among the several complications that may occur after a tattooing procedure, allergic and photo-allergic reactions, infections, and Koebner phenomenon are the most common ones observed. Most of these complications may be avoided by identifying, before tattooing, the presence of risk factors or comorbidities that may increase the risk of their onset.

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Clinical efficacy of dissolvable microneedles armed with anti-melanogenic compounds to counter hyperpigmentation

Muhammet Avcil PhD, Gokhan Akman PhD, Jens Klokkers PhD, Dohyeon Jeong PhD, Ayhan ?elik PhD

doi : 10.1111/jocd.13571

Volume 20, Issue 2 p. 605-614

Hyperpigmentation is a complex physiological process associated with alterations of skin color due to melanin overproduction and distribution.

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Frontal fibrosing alopecia and genital Lichen sclerosus: Single-center experience

Sara Grassi MD, Giulia Tadiotto Cicogna MD, Francesca Magri MD, Maria Caterina Fortuna MD, Gemma Caro MD, Angelina Pernazza MD, Giuseppe Soda MD, Emanuele Miraglia MD, Sandra Giustini MD, PhD, Marta Carlesimo MD, Alfredo Rossi MD, PhD

doi : 10.1111/jocd.13573

Volume 20, Issue 2 p. 615-620

Despite the incidence of Frontal fibrosing alopecia (FFA) has been increasing in last two decades, the pathophysiology and trigger factors of FFA have not been yet fully understood.

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Calprotectin in acne vulgaris: A possible contributory role

Ibrahim Fouda MD, Zakaria M. Obaid MD, Shimaa F. Hegazy MSc, Hesham Samir Abd Al-Samie MD, Ahmad Nofal MD

doi : 10.1111/jocd.13574

Volume 20, Issue 2 p. 621-625

Acne vulgaris (AV) is a common inflammatory skin disease involving dysfunction of the pilosebaceous unit. Many mechanisms for the pathogenesis of acne have been postulated; however, the precise pathogenesis is still uncertain.

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Transdermal delivery of topical lidocaine in a mouse model is enhanced by treatment with cold atmospheric plasma

Yue Xin MD, Xiang Wen MD?PhD, Michael R. Hamblin PhD, Xian Jiang MD, PhD

doi : 10.1111/jocd.13581

Volume 20, Issue 2 p. 626-635

Topical anesthetics are widely used in dermatology and cosmetology to alleviate the pain from nonsurgical cosmetic procedures, while the transdermal drug delivery is limited by the skin barrier. Cold atmospheric plasma (CAP) is a potential approach used for skin pretreatment to enhance transdermal delivery of topical medications.

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Innovative approach to aesthetical medicine services quality assessment

Olga Krasilnikova, Marina Pozdnyakova D.Sc. in Medicine

doi : 10.1111/jocd.13584

Volume 20, Issue 2 p. 636-646

Recently, both doctors and patients pay particular attention to aesthetic medical services quality and efficacy of aesthetic adjustment implemented.

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Elaeagnus L gum polysaccharides alleviate the impairment of barrier function in the dry skin model mice

Bingying Wang MD, Meiling Tai MD, Kun Zhang PhD, Huixiong Chen PhD, Xiaoshuang Gan MD, Biao Che DOC, N. Abudukelimu PhD, Guoping Wang PhD, Xuelei Xin PhD, Li Lin MD, Ping Han MD, Yi Peng MD, Zhiyun Du PhD, Haji Aker Aisa PhD

doi : 10.1111/jocd.13541

Volume 20, Issue 2 p. 647-656

Dry skin is a common skin condition caused by reduction of water-holding capacity, which is regulated by skin barrier function. Dry skin can also be a symptom that indicates a more serious diagnosis. There are a number of moisturizers on the market, which play an important role in dermatologic and cosmetic therapies. However, the demand for these products with good and therapeutic efficiency is still growing.

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Effect of oxybrasion on selected skin parameters

Sylwia Jarz?bek MSc, Helena Rotsztejn MD

doi : 10.1111/jocd.13557

Volume 20, Issue 2 p. 657-663

Oxybrasion is one of the types of microdermabrasion. This method removes a superficial epidermal layer with the use of a stream of 0.9% saline solution and compressed air.

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Target action of antioxidants using iontophoresis

Silas Arandas Monteiro e Silva PhD, Joel Gonçalves de Souza PhD, Priscilla Siqueira Melo PhD, Ivani Aparecida Marchetto Moreno Tech, Severino Matias Alencar PhD, Renata Fonseca Vianna Lopez PhD, Gislaine Ricci Leonardi PhD

doi : 10.1111/jocd.13560

Volume 20, Issue 2 p. 664-676

The use of antioxidants in applications for topical use seems promising, however, many studies must be performed to ensure processes and products that can effectively bring benefits to combat the action of free radicals in the skin. For topical antioxidants to be effective against free radicals from the skin, it is essential that the antioxidants compounds permeate the different skin layers, to reach deeper layers of the epidermis in active form and stay there for a sufficient time to cause the beneficial effects.

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New method for large-scale facial skin sebum quantification and skin type classification

Jingjing Qin, Liyuan Qiao, Jingjing Hu, Jichao Xu, Le Du, Qianqian Wang, Rui Ye

doi : 10.1111/jocd.13576

Volume 20, Issue 2 p. 677-683

The demand for personalized skin care is increasing rapidly in recent years. In order to provide suitable products for different customers, an accurate assessment of the skin condition is required. It is necessary to establish a remote and convenient method for quantifying skin condition.

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The effect of hypoxia on the proliferation capacity of dermal papilla cell by regulating lactate dehydrogenase

Jun Ye PhD, Xiaoli Tang MD, Yunzhu Long PhD, Zhou Chu MD, Qing Zhou MD, Bojie Lin PhD

doi : 10.1111/jocd.13578

Volume 20, Issue 2 p. 684-690

Hypoxia is of great significance for stem cells to maintain the proliferation and differentiation capacity. As a specialized mesenchymal component of the hair follicle (HF), the dermal papilla cell (DPC) not only regulates HF cycle, but also plays a pivotal role in differentiating hair follicle stem cell(HFSC) into HF. However, whether hypoxia could affect DPCs on proliferation or metabolism remains unclear.

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Purple tulip extract improves signs of skin aging through dermal structural modulation as shown by genomic, protein expression and skin appearance of volunteers studied

Neïla Hajem MSc, Léana Manzato MSc, Marie-Christine Branchet PhD, Amélie Herlin MSc, Shalina Hassanaly PhD, Elise Huguet MSc, Frank Himbert PhD, Philippe Bernard PhD, Anne-Sophie Dussert PhD, Jean-Christophe Choulot PhD, Sylvie Boisnic MD, Mayoura Kéophiphath PhD

doi : 10.1111/jocd.13583

Volume 20, Issue 2 p. 691-702

Purple tulip extract is a rich source of flavonoids which are powerful antioxidants and can hence be considered as an ideal candidate for use in skin care products.

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Utility of dermatoscopy in the diagnosis of Habit-Tic Nail Deformity

?mer Faruk Elmas MD, Abdullah Demirba? MD

doi : 10.1111/jocd.13551

Volume 20, Issue 2 p. 703-704

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Treatment of Becker's nevus with 577-nm pro-yellow laser: Could it be a new treatment choice?

Selami Aykut Temiz MD, Shohrat Arazov MD, Arzu Ataseven MD, Recep Dursun MD

doi : 10.1111/jocd.13882

Volume 20, Issue 2 p. 705-706

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