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Interleukin-17 inhibitor, is it safer than tumor necrosis factor inhibitor?
Jinxian Huang,Lijun Zhang,James C-C Wei
doi : 10.1111/1756-185X.14076
Volume 24, Issue 7 p. 865-868
Is denosumab associated with an increased risk for infection in patients with low bone mineral density? A systematic review and meta-analysis of randomized controlled trials
Brett Catton,Salman Surangiwala,Tanveer Towheed
doi : 10.1111/1756-185X.14101
Volume 24, Issue 7 p. 869-879
Denosumab increases bone mineral density through inhibition of the receptor activator of nuclear factor ?-? ligand (RANKL). RANKL has known immunomodulatory effect. The largest study to date that reviewed denosumab efficacy in osteoporosis demonstrated an increased incidence of serious adverse events of infection (SAEI). We aimed to further evaluate risk of infection and SAEI in denosumab-treated patients.
Prevention of infective complications in systemic lupus erythematosus: A systematic literature review for the APLAR consensus statements
Kenji Oku,Laniyati Hamijoyo,Nuntana Kasitanon,Meng Tao Li,Sandra Navarra,Eric Morand,Yoshiya Tanaka,Chi Chiu Mok
doi : 10.1111/1756-185X.14125
Volume 24, Issue 7 p. 880-895
Systemic lupus erythematosus (SLE) is a more common autoimmune rheumatic disease in the Asia-Pacific region. The prognosis of SLE remains unsatisfactory in some Asian countries because of delayed diagnosis, limited access to medications, increased complications and issues of tolerability and adherence to treatment. The Asia-Pacific League of Associations for Rheumatology SLE special interest group has recently published a set of consensus recommendations on the management of SLE for specialists, family physicians, specialty nurses, and other healthcare professionals in the Asia-Pacific region. This article reports a systematic literature review of the infective complications of SLE in Asia and evidence for prevention of these infections by pre-emptive antimicrobial therapy and vaccination.
The pathophysiological effects of exercise in the management of idiopathic inflammatory myopathies: A scoping review
Ilke Coskun Benlidayi,Latika Gupta
doi : 10.1111/1756-185X.14104
Volume 24, Issue 7 p. 896-903
Idiopathic inflammatory myopathy (IIM) is a term used for a heterogeneous group of diseases characterized by severe muscle weakness. In addition to pharmacological treatment options, non-pharmacological methods such as exercising are essential for proper management of myositis. The present article aimed to provide an insight into the potential pathophysiological mechanisms underlying exercise-related benefits in myositis. A systematic search was performed on PubMed/MEDLINE, Scopus, Web of Science, and Google Scholar using the following keywords and their combinations: “idiopathic inflammatory myopathy”, “inflammatory myopathy”, “myositis”, “polymyositis”, “dermatomyositis”, “inclusion body myositis”, and “exercise”. Current literature indicates that exercising has impact on both immune and non-immune pathways in patients with IIM. Exercise-related benefits include (a) increased mitochondrial biogenesis/enzyme activity, (b) reconditioning of immune/inflammatory pathways, (c) decreased endoplasmic reticulum stress, (d) modulation of gene expression, (e) increased protein synthesis and cytoskeletal remodeling, and (f) decreased muscle fibrosis and non-muscle area infiltrates. With its certain benefits, exercise stands as a precious non-pharmacological treatment option for patients with IIM.
The impact of antineutrophil cytoplasmic antibody-associated vasculitis on employment and work disability in an Australian population
Vanessa Heron,Michael Gingold,Arthur R. Kitching,Kevan R. Polkinghorne,Jessica Ryan
doi : 10.1111/1756-185X.14131
Volume 24, Issue 7 p. 904-911
Although antineutrophil cytoplasmic antibody-associated vasculitis (AAV) most commonly affects older individuals, many patients develop the disease during their most productive working years. The aim of this study was to examine the effects of AAV on employment and work disability in a cohort of Australian patients of working age.
Effect of patient-led cooperative follow-up by general practitioners and community pharmacists on osteoporosis treatment persistence
Didier Poivret,Christophe Goetz,Yinka Zevering,Christophe Wilcke,Véronique Noirez
doi : 10.1111/1756-185X.14146
Volume 24, Issue 7 p. 912-921
Osteoporosis is a major risk factor for fractures. Poor persistence with osteoporosis medication hampers outcomes. This study assessed whether encouraging the formation of patient-led follow-up cooperatives between general practitioners (GPs) and community pharmacists improved medication persistence.
Survivin promotes rheumatoid arthritis fibroblast-like synoviocyte cell proliferation, and the expression of angiogenesis-related proteins by activating the NOTCH pathway
Sha Ma,Jing Wang,Jun Lin,Song Jin,Fang He,Jian Mei,Hong Zhang,Shuya Wang,Qin Li
doi : 10.1111/1756-185X.14150
Volume 24, Issue 7 p. 922-929
Survivin have been shown to play a crucial role in rheumatoid arthritis (RA); however, the regulatory mechanism of survivin in RA has not been fully elucidated. This study aims to investigate the effect of survivin on the proliferation and apoptosis of human RA fibroblast-like synoviocyte (RA-HFLS) cells in RA and its underlying mechanism through the NOTCH pathway.
Efficacy of aqua-based plyometric exercises in the rehabilitation of patients with juvenile dermatomyositis: A randomized crossover pilot study
Ragab K. Elnaggar,Walaa A. Abd El-Nabie
doi : 10.1111/1756-185X.14152
Volume 24, Issue 7 p. 930-940
Patients with juvenile dermatomyositis (JDM) experience muscle weakness, tiredness, and loss of energy, which restrict their abilities in performance of their daily living activities.
Greater trochanteric pain syndrome in women: Analysis of magnetic resonance, sagittal alignment, muscular strength and endurance of the hip and trunk
Maur?cio Rodrigues Miyasaki,Marieli Araujo Rossoni Marcioli,Amanda Paula Ricardo Rodrigues da Cunha,Giancarlo Cavalli Polesello,Marcelo Garcia Marini,Karen Barros Parron Fernandes,Christiane de Souza Guerino Macedo
doi : 10.1111/1756-185X.14149
Volume 24, Issue 7 p. 941-947
There are many studies on the Greater Trochanteric Pain Syndrome (GTPS), however its relationship with radiographic and biomechanics parameters is not established.
Evaluation of bone erosion in rheumatoid arthritis patients by high-resolution peripheral quantitative computed tomography scans: Comparison between two semi-automated programs in a three-dimensional setting
Camille Pinto Figueiredo,Mariana Ortega Perez,Lucas Peixoto Sales,Valeria de Falco Caparbo,Rosa Maria Rodrigues Pereira
doi : 10.1111/1756-185X.14157
Volume 24, Issue 7 p. 948-953
The aim of this study was to compare OsiriX software with the previous published Medical Image Analysis Framework (MIAF) method to assess the volume of erosion in patients with rheumatoid arthritis (RA).
Arterial evaluation of systemic sclerosis patients with Doppler ultrasound: What did we find?
Suade Ozlem Badak,Bozkurt Gulek,Esra Kayacan Erdogan,Hulya B?nokay,Eren Erken
doi : 10.1111/1756-185X.14158
Volume 24, Issue 7 p. 954-962
The aim of this study was to detect macrovascular findings in systemic sclerosis (SSc) by means of color Doppler ultrasonography (CDUS) and to evaluate the relationship between the laboratory and clinical findings in the setting of the disease.
Will the COVID-19 pandemic trigger future occurrence of autoimmunity like Sj?gren’s syndrome?
Kayo Masuko
doi : 10.1111/1756-185X.14154
Volume 24, Issue 7 p. 963-965
Recent advances in pediatric rheumatology: January to March 2021
Archan Sil,Prabal Barman,Surjit Singh
doi : 10.1111/1756-185X.14159
Volume 24, Issue 7 p. 966-969
Takayasu arteritis developing during the course of palmoplantar pustulosis
Masahiro Kondo,Yohko Murakawa,Sakae Kaneko,Teruaki Iwahashi,Manabu Honda,Mayuko Moriyama
doi : 10.1111/1756-185X.14161
Volume 24, Issue 7 p. 970-972
Your help is needed in the fight against COVID-19: Please contribute to the COVID-19 Global rheumatology alliance registry
doi : 10.1111/1756-185X.14118
Volume 24, Issue 7 p. 973-973
