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Transformative Medical Materials (Adv. Healthcare Mater. 20/2023)

Laura De Laporte, Fabian Kiessling

doi : 10.1002/adhm.202370111

Volume 12, Issue 20

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Mesenchymal Stem Cell Aggregation-Released Extracellular Vesicles Induce CD31+EMCN+ Vessels in Skin Regeneration and Improve Diabetic Wound Healing (Adv. Healthcare Mater. 20/2023)

Lu Liu, Chen-Xi Zheng, Na Zhao, Ting Zhu, Cheng-Biao Hu, Nan Zhang, Ji Chen, Kai-Chao Zhang, Sha Zhang, Jie-Xi Liu, Kai Zhang, Huan Jing, Bing-Dong Sui, Yan Jin, Fang Jin

doi : 10.1002/adhm.202370112

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MY-1-Loaded Nano-Hydroxyapatite Accelerated Bone Regeneration by Increasing Type III Collagen Deposition in Early-Stage ECM via a Hsp47-Dependent Mechanism (Adv. Healthcare Mater. 20/2023)

Zhang Yanli, Mo Jiayao, Zheng Chunqing, Zeng Yuting, Zhou Zhiyan, Zhang Yulin, Li Minghan, Shao Longquan, Yang Dehong, Yan Wenjuan

doi : 10.1002/adhm.202370118

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Unusual Surface Coagulation Activation Patterns of Crystalline and Amorphous Silicate-Based Biominerals (Adv. Healthcare Mater. 20/2023)

Chunyu Liu, Xu Cui, Yunbo Du, Xue Wang, Jua Kim, Shuaijie Li, Liyan Zhang, Xiaoli Zhao, Limin Zhao, Pengfei Tian, Hao Zhang, Kun Su, Xian Li, Haobo Pan

doi : 10.1002/adhm.202370119

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Masthead: (Adv. Healthcare Mater. 20/2023)

doi : 10.1002/adhm.202370113

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Transformative Materials to Create 3D Functional Human Tissue Models In Vitro in a Reproducible Manner

Jose L. Gerardo-Nava, Jitske Jansen, Daniel Günther, Laura Klasen, Anja Lena Thiebes, Bastian Niessing, Cédric Bergerbit, Anna A. Meyer, John Linkhorst, Mareike Barth, Payam Akhyari, Julia Stingl, Saskia Nagel, Thomas Stiehl, Angelika Lampert, Rudolf Leube, Matthias Wessling, Francesca Santoro, Sven Ingebrandt, Stefan Jockenhoevel, Andreas Herrmann, Horst Fischer, Wolfgang Wagner, Robert H. Schmitt, Fabian Kiessling, Rafael Kramann, Laura De Laporte

doi : 10.1002/adhm.202301030

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Lifelike Transformative Materials for Biohybrid Implants: Inspired by Nature, Driven by Technology

Alicia Fernández-Colino, Fabian Kiessling, Ioana Slabu, Laura De Laporte, Payam Akhyari, Saskia K. Nagel, Julia Stingl, Stefanie Reese, Stefan Jockenhoevel

doi : 10.1002/adhm.202300991

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Toward the Next Generation of Neural Iontronic Interfaces

Csaba Forró, Simon Musall, Viviana Rincón Montes, John Linkhorst, Peter Walter, Matthias Wessling, Andreas Offenhäusser, Sven Ingebrandt, Yvonne Weber, Angelika Lampert, Francesca Santoro

doi : 10.1002/adhm.202301055

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Transformative Materials for Interfacial Drug Delivery

Prachi Desai, Anshuman Dasgupta, Alexandros Marios Sofias, Quim Peña, Robert Göstl, Ioana Slabu, Ulrich Schwaneberg, Thomas Stiehl, Wolfgang Wagner, Stefan Jockenhövel, Julia Stingl, Rafael Kramann, Christian Trautwein, Tim H. Brümmendorf, Fabian Kiessling, Andreas Herrmann, Twan Lammers

doi : 10.1002/adhm.202301062

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Plant-Derived Biomaterials and Their Potential in Cardiac Tissue Repair

Yichen Dai, Kai Qiao, Demin Li, Phocas Isingizwe, Haohao Liu, Yu Liu, Khoon Lim, Tim Woodfield, Guozhen Liu, Jinming Hu, Jie Yuan, Junnan Tang, Xiaolin Cui

doi : 10.1002/adhm.202202827

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Hyaluronic Acid-Based Bioconjugate Systems, Scaffolds, and Their Therapeutic Potential

Niranjan G. Kotla, Isma Liza Mohd Isa, Aitor Larrañaga, Balaji Maddiboyina, Samantha K. Swamy, Gandhi Sivaraman, Praveen K. Vemula

doi : 10.1002/adhm.202203104

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Recent Advances in Organ-on-Chips Integrated with Bioprinting Technologies for Drug Screening

Nima Tabatabaei Rezaei, Hitendra Kumar, Hongqun Liu, Samuel S. Lee, Simon S. Park, Keekyoung Kim

doi : 10.1002/adhm.202203172

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Integration of Extracellular Matrices into Organ-on-Chip Systems

Hazal Kutluk, Effie E. Bastounis, Iordania Constantinou

doi : 10.1002/adhm.202203256

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Recent Advancements on Self-Immolative System Based on Dynamic Covalent Bonds for Delivering Heterogeneous Payloads

Qingbing Wang, Maciej Serda, Quan Li, Tao Sun

doi : 10.1002/adhm.202300138

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Tumor Therapy Strategies Based on Microenvironment-Specific Responsive Nanomaterials

Zhaocong Zhang, Chengwen Ding, Tiedong Sun, Lei Wang, Chunxia Chen

doi : 10.1002/adhm.202300153

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Nanomedicine-Based Therapeutics for Myocardial Ischemic/Reperfusion Injury

Xi Li, Wei Ou, Maodi Xie, Jing Yang, Qian Li, Tao Li

doi : 10.1002/adhm.202300161

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Tailored Beta-Lapachone Nanomedicines for Cancer-Specific Therapy

Yaru Li, Meiyu Feng, Tao Guo, Zheng Wang, Yanjun Zhao

doi : 10.1002/adhm.202300349

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Mesenchymal Stem Cell Aggregation-Released Extracellular Vesicles Induce CD31+EMCN+ Vessels in Skin Regeneration and Improve Diabetic Wound Healing

Lu Liu, Chen-Xi Zheng, Na Zhao, Ting Zhu, Cheng-Biao Hu, Nan Zhang, Ji Chen, Kai-Chao Zhang, Sha Zhang, Jie-Xi Liu, Kai Zhang, Huan Jing, Bing-Dong Sui, Yan Jin, Fang Jin

doi : 10.1002/adhm.202300019

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MY-1-Loaded Nano-Hydroxyapatite Accelerated Bone Regeneration by Increasing Type III Collagen Deposition in Early-Stage ECM via a Hsp47-Dependent Mechanism

Zhang Yanli, Mo Jiayao, Zheng Chunqing, Zeng Yuting, Zhou Zhiyan, Zhang Yulin, Li Minghan, Shao Longquan, Yang Dehong, Yan Wenjuan

doi : 10.1002/adhm.202300332

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Unusual Surface Coagulation Activation Patterns of Crystalline and Amorphous Silicate-Based Biominerals

Chunyu Liu, Xu Cui, Yunbo Du, Xue Wang, Jua Kim, Shuaijie Li, Liyan Zhang, Xiaoli Zhao, Limin Zhao, Pengfei Tian, Hao Zhang, Kun Su, Xian Li, Haobo Pan

doi : 10.1002/adhm.202300039

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Crocetin Regulates Functions of Neural Stem Cells to Generate New Neurons for Cerebral Ischemia Recovery (Adv. Healthcare Mater. 20/2023)

Zhongqing Liu, Zhaojun Wang, Zhanchi Zhu, Jing Hong, Leisha Cui, Ying Hao, Guosheng Cheng, Rui Tan

doi : 10.1002/adhm.202370114

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Crocetin Regulates Functions of Neural Stem Cells to Generate New Neurons for Cerebral Ischemia Recovery

Zhongqing Liu, Zhaojun Wang, Zhanchi Zhu, Jing Hong, Leisha Cui, Ying Hao, Guosheng Cheng, Rui Tan

doi : 10.1002/adhm.202203132

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Injury Site Specific Xenon Delivered by Platelet Membrane-Mimicking Hybrid Microbubbles to Protect Against Acute Kidney Injury via Inhibition of Cellular Senescence (Adv. Healthcare Mater. 20/2023)

Jing Yang, Chaojin Chen, Xiaoyan Miao, Tienan Wang, Yu Guan, Linan Zhang, Sufang Chen, Zheng Zhang, Zhengyuan Xia, Jiayi Kang, Haobo Li, Tinghui Yin, Ziqing Hei, Weifeng Yao

doi : 10.1002/adhm.202370115

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Injury Site Specific Xenon Delivered by Platelet Membrane-Mimicking Hybrid Microbubbles to Protect Against Acute Kidney Injury via Inhibition of Cellular Senescence

Jing Yang, Chaojin Chen, Xiaoyan Miao, Tienan Wang, Yu Guan, Linan Zhang, Sufang Chen, Zheng Zhang, Zhengyuan Xia, Jiayi Kang, Haobo Li, Tinghui Yin, Ziqing Hei, Weifeng Yao

doi : 10.1002/adhm.202203359

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A Bioinspired Gelatin–Amorphous Calcium Phosphate Coating on Titanium Implant for Bone Regeneration (Adv. Healthcare Mater. 20/2023)

Yanhuizhi Feng, Di Wu, Jennifer Knaus, Sascha Keßler, Bing Ni, ZongKun Chen, Johnathan Avaro, Rui Xiong, Helmut Cölfen, Zuolin Wang

doi : 10.1002/adhm.202370116

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A Bioinspired Gelatin–Amorphous Calcium Phosphate Coating on Titanium Implant for Bone Regeneration

Yanhuizhi Feng, Di Wu, Jennifer Knaus, Sascha Keßler, Bing Ni, ZongKun Chen, Johnathan Avaro, Rui Xiong, Helmut Cölfen, Zuolin Wang

doi : 10.1002/adhm.202203411

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A Non-G-Quadruplex DNA Aptamer Targeting NCL for Diagnosis and Therapy in Bladder Cancer (Adv. Healthcare Mater. 20/2023)

Yunyi Liu, Bei Hu, Xiaming Pei, Juan Li, Dan Qi, Yuxi Xu, Hailong Ou, Yatao Wu, Lei Xue, Jason H. Huang, Erxi Wu, Xiaoxiao Hu

doi : 10.1002/adhm.202370117

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A Non-G-Quadruplex DNA Aptamer Targeting NCL for Diagnosis and Therapy in Bladder Cancer

Yunyi Liu, Bei Hu, Xiaming Pei, Juan Li, Dan Qi, Yuxi Xu, Hailong Ou, Yatao Wu, Lei Xue, Jason H. Huang, Erxi Wu, Xiaoxiao Hu

doi : 10.1002/adhm.202300791

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Collagen Hydrogel Containing Polyethylenimine-Gold Nanoparticles for Drug Release and Enhanced Beating Properties of Engineered Cardiac Tissues

Kaveh Roshanbinfar, Maria Kolesnik-Gray, Miriam Angeloni, Stefan Schruefer, Maren Fiedler, Dirk W. Schubert, Fulvia Ferrazzi, Vojislav Krstic, Felix B. Engel

doi : 10.1002/adhm.202202408

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Engineering a Two-Component Hemostat for the Treatment of Internal Bleeding through Wound-Targeted Crosslinking

Celestine Hong, Yanpu He, Porter A. Bowen, Angela M. Belcher, Bradley D. Olsen, Paula T. Hammond

doi : 10.1002/adhm.202202756

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Nature-Skin-Derived e-Skin as Versatile “Wound Therapy-Health Monitoring� Bioelectronic Skin-Scaffolds: Skin to Bio-e-Skin

Xinhua Liu, Boqiang Cui, Xuechuan Wang, Manhui Zheng, Zhongxue Bai, Ouyang Yue, Yifan Fei, Huie Jiang

doi : 10.1002/adhm.202202971

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Macrophages-Cancer Membrane-Encapsulated Metal−Organic Frameworks with Copper-Depleting Moiety for Mitochondria-Targeted Therapeutics

Weiqun Li, Mingjie Dong, Yingchun Li, Haifeng Dong

doi : 10.1002/adhm.202202986

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3D Printing of Extracellular Matrix-Based Multicomponent, All-Natural, Highly Elastic, and Functional Materials toward Vascular Tissue Engineering

Melis Isik, Ece Karakaya, Tugba Sezgin Arslan, Deniz Atila, Yasar Kemal Erdogan, Yavuz Emre Arslan, Hakan Eskizengin, Cemil Can Eylem, Emirhan Nemutlu, Batur Ercan, Matteo D'Este, Babatunde O. Okesola, Burak Derkus

doi : 10.1002/adhm.202203044

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Self-Assembled Carrier-Free Nanodrugs for Starvation Therapy-Amplified Photodynamic Therapy of Cancer

Dong-Yang Zhang, Yuqin Liang, Mingcheng Wang, Muhammad Rizwan Younis, Huixi Yi, Xiaoya Zhao, Jishuo Chang, Yue Zheng, Weisheng Guo, Xiyong Yu

doi : 10.1002/adhm.202203177

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Multifunctional Antibacterial Nanonets Attenuate Inflammatory Responses through Selective Trapping of Endotoxins and Pro-Inflammatory Cytokines

Nhan Dai Thien Tram, Quy Thi Ngoc Tran, Jian Xu, Jeannie Ching Ting Su, Wupeng Liao, Wai Shiu Fred Wong, Pui Lai Rachel Ee

doi : 10.1002/adhm.202203232

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In Situ Formed ROS-Responsive Hydrogel with STING Agonist and Gemcitabine to Intensify Immunotherapy against Pancreatic Ductal Adenocarcinoma

Meng Wang, Qida Hu, Junming Huang, Fu Zhang, Zhuo Yao, Shiyi Shao, Xinyu Zhao, Tingbo Liang

doi : 10.1002/adhm.202203264

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Plant Protein-Peptide Supramolecular Polymers with Reliable Tissue Adhesion for Surgical Sealing

Junlian Nie, Yingchuan Sun, Xueliang Cheng, Guang Wen, Xiaohuan Liu, Meng Cheng, Jianwu Zhao, Wen Li

doi : 10.1002/adhm.202203301

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Alleviate Periodontitis and Its Comorbidity Hypertension using a Nanoparticle-Embedded Functional Hydrogel System

Shuo Xu, Bin Hu, Ting Dong, Bo-Yan Chen, Xiao-Jian Xiong, Lin-Juan Du, Yu-Lin Li, Yan-Lin Chen, Guo-Cai Tian, Xue-Bing Bai, Ting Liu, Lu-Jun Zhou, Wu-Chang Zhang, Yan Liu, Qin-Feng Ding, Xue-Qing Zhang, Sheng-Zhong Duan

doi : 10.1002/adhm.202203337

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Bio-Inspired Antioxidant Heparin-Mimetic Peptide Hydrogel for Radiation-Induced Skin Injury Repair

Yusen Hao, Hui Li, Jiajun Guo, Dan Wang, Jiamin Zhang, Jinjian Liu, Cuihong Yang, Yumin Zhang, Guoliang Li, Jianfeng Liu

doi : 10.1002/adhm.202203387

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Light-Triggered Nitric Oxide Nanogenerator with High l-Arginine Loading for Synergistic Photodynamic/Gas/Photothermal Therapy

Hui Shi, Cheng-Feng Xiong, Lin-Jun Zhang, Hu-Chen Cao, Ru Wang, Pei Pan, Hai-Yan Guo, Tao Liu

doi : 10.1002/adhm.202300012

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Disulfide-Bridged Dendritic Organosilicas-Based Biodegradable Molecularly Imprinted Polymers for Multiple Targeting and pH/Redox-Responsive Drug Release toward Chemical/Photodynamic Synergistic Tumor Therapy

Shiwei Liu, Shuang Han, Yuzhuo Song, Ruonan Sun, Le Zhao, Chen Yan

doi : 10.1002/adhm.202300184

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Breaking a Dogma: High-Throughput Live-Cell Imaging in Real-Time with Hoechst 33342

Heiko Fuchs, Kirsten Jahn, Xiaonan Hu, Roland Meister, Maximilian Binter, Carsten Framme

doi : 10.1002/adhm.202300230

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Bacteria-Targeted Combined with Photothermal/NO Nanoparticles for the Treatment and Diagnosis of MRSA Infection In Vivo

Kai Lv, Guowei Li, Xiangjun Pan, Luxuan Liu, Ziheng Chen, Yu Zhang, Hao Xu, Dong Ma

doi : 10.1002/adhm.202300247

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Zinc-Based Tannin-Modified Composite Microparticulate Scaffolds with Balanced Antimicrobial Activity and Osteogenesis for Infected Bone Defect Repair

Yitao Zhao, Jintao Li, Lingli Liu, Yue Wang, Yan Ju, Chun Zeng, Zhihui Lu, Denghui Xie, Jinshan Guo

doi : 10.1002/adhm.202300303

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Specific Spleen-Accumulated NIR-II Fluorescent Probe for Imaging-Guided Splenic Operation

Yiqing Yang, Diankai Liu, Zixu He, Xiaofan Zhang, Huihui Liu, Xiaohua Li, Huimin Ma, Wen Shi

doi : 10.1002/adhm.202300434

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Mesenchymal Stem Cell Culture within Perfusion Bioreactors Incorporating 3D-Printed Scaffolds Enables Improved Extracellular Vesicle Yield with Preserved Bioactivity

Stephanie M. Kronstadt, Divya B. Patel, Louis J. Born, Daniel Levy, Max J. Lerman, Bhushan Mahadik, Shannon T. McLoughlin, Arafat Fasuyi, Lauren Fowlkes, Lauren Hoorens Van Heyningen, Amaya Aranda, Sanaz Nourmohammadi Abadchi, Kai-Hua Chang, Angela Ting Wei Hsu, Sameer Bengali, John W. Harmon, John P. Fisher, Steven M. Jay

doi : 10.1002/adhm.202300584

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Sequential Dual-Biofactor Release from the Scaffold of Mesoporous HA Microspheres and PLGA Matrix for Boosting Endogenous Bone Regeneration

Jiawei Wei, Xue Xia, Shiqi Xiao, Shue Jin, Qin Zou, Yi Zuo, Yubao Li, Jidong Li

doi : 10.1002/adhm.202300624

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