American Journal of Respiratory and Critical Care Medicine




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February 1 Highlight

doi : 10.1164/rccm.2073Pxiv

Volume 207, Issue 3 | February 1 2023

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Understanding the Role of Mesenchymal Stromal Cells in Treating COVID-19 Acute Respiratory Distress Syndrome

Cecilia M. O’Kane 1 and Michael A. Matthay 2,3

doi : 10.1164/rccm.202209-1838ED  

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To Intubate or Not Intubate, That Is the Question

Gaurav S. Ajmani and Bhakti K. Patel

doi : 10.1164/rccm.202209-1823ED

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NOTCH-ing up Surface Tension in the Fibrotic Lung

Joseph A. Lasky and Victor J. Thannickal

doi : 10.1164/rccm.202210-1901ED

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Comparing the Incomparable: Identifying Common Themes Across a Diverse Landscape to Address Equity in Lung Allocation

Hilary J. Goldberg

doi : 10.1164/rccm.202209-1816ED

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Improved Survival for Patients with Systemic Sclerosis–associated Pulmonary Arterial Hypertension: For Real?

Panagiota Xanthouli 1,2

doi : 10.1164/rccm.202210-2006ED

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miR-roring Changes in Blood: miR-210 Reflects Hypoxic Disease Dynamics in Obstructive Sleep Apnea

Anna Kirillova 1,2 and Stephen Y. Chan 1

doi : 10.1164/rccm.202209-1709ED  

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Tuberculosis, Wildfires, and Case-crossover Studies: An Epidemiological Trifecta?

William Checkley

doi : 10.1164/rccm.202210-1936ED

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Moving toward Equitable Care for Sleep Apnea in the United States: Positive Airway Pressure Adherence Thresholds: An Official American Thoracic Society Policy Statement

Anna M. May , Sanjay R. Patel , Motoo Yamauchi , Tilak K. Verma , Terri E. Weaver , Ching Li Chai-Coetzer , J. Daryl Thornton , Gary Ewart , Terrance Showers , Najib T. Ayas , Sairam Parthasarathy , Reena Mehra , and Martha E. Billings ; on behalf of the American Thoracic Society Sleep and Respiratory Neurobiology Assembly ... Show less

doi : 10.1164/rccm.202210-1846ST

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Rethinking Acute Respiratory Distress Syndrome after COVID-19: If a “Better� Definition Is the Answer, What Is the Question?

V. Marco Ranieri 1*, Gordon Rubenfeld 2*, and Arthur S. Slutsky 3,4*

doi : 10.1164/rccm.202206-1048CP

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A Randomized Trial of Mesenchymal Stromal Cells for Moderate to Severe Acute Respiratory Distress Syndrome from COVID-19

Michael E. Bowdish 1*, Christina E. Barkauskas 2*, Jessica R. Overbey 3, Robert L. Gottlieb 4, Keren Osman 5, Abhijit Duggal 6, Mary E. Marks 3, Jonathan Hupf 3, Eustace Fernandes 7, Bradley G. Leshnower 8, Jonathan L. Golob 9, Alexander Iribarne 10, Athos J. Rassias 10, Ellen G. Moquete 3, Karen O’Sullivan 3, Helena L. Chang 3, Judson B. Williams 11, Sam Parnia 12, Nirav C. Patel 13, Nimesh D. Desai 14, Andrew M. Vekstein 15, Beth A. Hollister 15, Tammie Possemato 1, Christian Romero 1, Peter C. Hou 16, Elizabeth Burke 17, Jack Hayes 17, Fred Grossman 17, Silviu Itescu 17, Marc Gillinov 18, Francis D. Pagani 19, Patrick T. O’Gara 20, Michael J. Mack 21, Peter K. Smith 15, Emilia Bagiella 3, Alan J. Moskowitz 3*, and Annetine C. Gelijns 3* ... Show less

doi : 10.1164/rccm.202201-0157OC

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Do Thresholds for Invasive Ventilation in Hypoxemic Respiratory Failure Exist? A Cohort Study

Christopher J. Yarnell 1,2,3, Alistair Johnson 4, Tariq Dam 5, Annemijn Jonkman 6, Kuan Liu 3, Hannah Wunsch 1,3,7, Laurent Brochard 1,8, Leo Anthony Celi 9,10,11, Harm-Jan De Grooth 5, Paul Elbers 5, Sangeeta Mehta 1,2, Laveena Munshi 1,2, Robert A. Fowler 1,3,12,13,14, Lillian Sung 3,14, and George Tomlinson 3,15 ... Show less

doi : 10.1164/rccm.202206-1092OC  

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Notch1 Induces Defective Epithelial Surfactant Processing and Pulmonary Fibrosis

Roxana Wasnick 1, Martina Korfei 1, Katarzyna Piskulak 1, Ingrid Henneke 1,2,3, Jochen Wilhelm 1,2,3, Poornima Mahavadi 1,2, Ruth Charlotte Dartsch 1, Daniel von der Beck 1, Miriam Koch 1,4, Irina Shalashova 1, Astrid Weiss 1, Oleksiy Klymenko 1, Ingolf Askevold 5, Ludger Fink 6, Heiko Witt 7, Holger Hackstein 8, Elie El Agha 1,2,3, Saverio Bellusci 1,2,3, Walter Klepetko 9, Melanie Königshoff 10,11, Oliver Eickelberg 11, Ralph Theo Schermuly 1,2,3, Thomas Braun 1,2,3,12, Werner Seeger 1,2,3,12, Clemens Ruppert 1,2,13*, and Andreas Guenther 1,2,3,4,13* ... Show less

doi : 10.1164/rccm.202105-1284OC

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The Lung Allocation Score Remains Inequitable for Patients with Pulmonary Arterial Hypertension, Even after the 2015 Revision

Nicholas A. Kolaitis 1, Hubert Chen 1,2, Daniel R. Calabrese 1, Kerry Kumar 3, Jill Obata 3, Carrie Bach 3, Jeffrey A. Golden 1, Marc A. Simon 1, Jasleen Kukreja 3, Steven R. Hays 1, Lorriana E. Leard 1, Jonathan P. Singer 1, and Teresa De Marco 1 ... Show less

doi : 10.1164/rccm.202201-0217OC

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Improved Survival for Patients with Systemic Sclerosis–associated Pulmonary Arterial Hypertension: The Johns Hopkins Registry

Hussein J. Hassan 1, Mario Naranjo 1, Nour Ayoub 1, Traci Housten 1, Steven Hsu 2, Aparna Balasubramanian 1, Catherine E. Simpson 1, Rachel L. Damico 1, Stephen C. Mathai 1, Todd M. Kolb 1, and Paul M. Hassoun 1

doi : 10.1164/rccm.202204-0731OC

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Obstructive Sleep Apnea–induced Endothelial Dysfunction Is Mediated by miR-210

Fenqing Shang 1,2*, Shen-Chih Wang 3,4*, Brendoan Gongol 5*, So Yun Han 5, Yoshitake Cho 5, Cara R. Schiavon 6, Lili Chen 2, Yuanming Xing 2, Yingshuai Zhao 7, Ming’an Ning 8, Xuan Guo 8, Fangzhou He 2, Yuyang Lei 2, Liuyi Wang 7, Uri Manor 6, Traci Marin 5,9, Kun-Ta Chou 4,10, Ming He 5, Po-Hsun Huang 11,12, John Y.-J. Shyy 5, and Atul Malhotra 13 ... Show less

doi : 10.1164/rccm.202202-0394OC  

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Tuberculosis Diagnoses Following Wildfire Smoke Exposure in California

Lauren R. Linde 1,2, Adam Readhead 1, Pennan M. Barry 1, John R. Balmes 2,3, and Joseph A. Lewnard 2,4

doi : 10.1164/rccm.202203-0457OC

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The Effects of Air Pollution in Pediatric Respiratory Disease

Sarah E. Bauer 1,2, Eli Rhoads 1,2, Brittany L. Wall 1,2, and Don B. Sanders 1,2

doi : 10.1164/rccm.202107-1583RR

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Obstructive Bronchial Fibrin Cast Formation in COVID-19 Severe Respiratory Failure

Jenna L. Bodmer 1, Jason Weinman 2, Livia A. Veress 3, and Csaba Galambos 1

doi : 10.1164/rccm.202201-0225IM

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Pulmonary Embolus and Hemoptysis Revealing Rare Intralobar Sequestration

Niamh Boyle 1, Darragh K. Waters 2, Jeff McCann 2, Marcus Butler 1,3, Jonathan D. Dodd 2,3, and Cormac McCarthy 1,3

doi : 10.1164/rccm.202206-1196IM

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Replacement Fibrosis in the Diaphragm of Mechanically Ventilated Critically Ill Patients

Zhonghua Shi 12*,, Marloes van den Berg 2*, Sylvia Bogaards 2, Stefan Conijn 2, Marinus Paul 2, Albertus Beishuizen 3, Leo Heunks 2,4, and Coen A. C. Ottenheijm 2,5‡

doi : 10.1164/rccm.202208-1608LE  

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Circulating Biomarkers in Young Individuals with Low Peak FEV1

Nuria Olvera 1,2, Sandra Casas 1,2, Judith M. Vonk 3,4, Tamara Garcia 1,2, H. Marike Boezen 3,4, Maarten van den Berge 4, Alvar Agusti 1,2,5,6, and Rosa Faner 1,2,5*

doi : 10.1164/rccm.202205-0855LE

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Critical Illness Myopathy Alters Diaphragm Neuromuscular Junction Protein and Gene Expression

Ashley J. Smuder 1*, Sanford Levine 2, and Scott K. Powers 1

doi : 10.1164/rccm.202204-0683LE

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Obstructive Sleep Apnea Symptoms Do Not Identify Patients at Risk of Chronic Kidney Disease

Andrew E. Beaudin 1, Jill K. Raneri 2, A.J. Marcus Hirsch Allen 3, Fréderic Series 4, R. John Kimoff 5, Robert P. Skomro 6, , Najib T. Ayas 3, Diego R. Mazzotti 7, Brendan T. Keenan 8, and Patrick J. Hanly 1,2*; on behalf of the Canadian Sleep and Circadian Network

doi : 10.1164/rccm.202207-1297LE

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Lung Cancer Attributable to Environmental Risk Factors

Ya-Yu Lee 1*, Chia-Chin Wu 1*, Yih-Jyh Lee 1*, Cho-Han Chiang 2, Kevin Sheng-Kai Ma 3,4,5‡, and James Cheng-Chung Wei 1,6,7,‡

doi : 10.1164/rccm.202208-1618LE

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Reply to Lee et al.

Fei Wang , Ni Li *,‡, and Jie He ‡; on behalf of all the authors

doi : 10.1164/rccm.202209-1693LE

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Definition of Chronic Obstructive Pulmonary Disease: Occupational Environmental Contribution

Philip Harber *

doi : 10.1164/rccm.202208-1496LE   

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Chronic Obstructive Pulmonary Disease Definition: Is It Time to Incorporate the Concept of Failure of Lung Regeneration?

Marco Confalonieri 1,2*, Luca Braga 3, Francesco Salton 1,2, Barbara Ruaro 1,2, and Paola Confalonieri 1,2

doi : 10.1164/rccm.202208-1508LE

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Reply to Harber and to Confalonieri et al.

Bartolome Celli 1* and Leonardo Fabbri 2; on behalf of all the authors

doi : 10.1164/rccm.202209-1749LE

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Functional Criteria to Define Progressive Pulmonary Fibrosis: Searching for the Holy Grail

María Noboa-Sevilla 1, Fernanda Hernández-González 1,2, Xavier Alsina-Restoy 1, Nancy Pérez-Rodas 1, and Jacobo Sellarés 1,2,3*

doi : 10.1164/rccm.202209-1772LE   

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Reply to Noboa-Sevilla et al.

Janelle Vu Pugashetti 1, Chad A. Newton 2, Philip L. Molyneaux 3,4, and Justin M. Oldham 1*

doi : 10.1164/rccm.202209-1807LE

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Early Life Exposure to Tobacco Smoke and Lung Cancer in Adulthood

Nuozhou Liu and Wei Xiong *

doi : 10.1164/rccm.202208-1542LE

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Reply to Liu and Xiong

Heng He and Rong Zhong *

doi : 10.1164/rccm.202209-1805LE

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