Acta Pharmacologica Sinica




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Regulated cell death pathways in cardiomyopathy

Shu-yuan Sheng, Jia-min Li, Xin-yang Hu & Yibin WangÂ

doi : 10.1038/s41401-023-01068-9

Volume 44 Issue 8, August 2023

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A new glance at autophagolysosomal-dependent or -independent function of transcriptional factor EB in human cancer

Ting Wang, Yi Qin, Zeng Ye, De-sheng Jing, Gui-xiong Fan, Meng-qi Liu, Qi-feng Zhuo, Shun-rong Ji, Xue-min Chen, Xian-jun Yu, Xiao-wu Xu & Zheng LiÂ

doi : 10.1038/s41401-023-01078-7

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RIPK1 inhibition contributes to lysosomal membrane stabilization in ischemic astrocytes via a lysosomal Hsp70.1B-dependent mechanism

Hua-ping Du, Yi Guo, Yong-ming Zhu, De-fei Gao, Bo Lin, Yuan Liu, Yuan Xu, Ali Said, Taous Khan, Li-jun Liu, Jian-jun Zhu, Yong Ni & Hui-ling ZhangÂ

doi : 10.1038/s41401-023-01069-8

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Quinpirole ameliorates nigral dopaminergic neuron damage in Parkinson’s disease mouse model through activating GHS-R1a/D2R heterodimers

Ting-ting Tang, Ming-xia Bi, Mei-ning Diao, Xiao-yi Zhang, Ling Chen, Xue Xiao, Qian Jiao, Xi Chen, Chun-ling Yan, Xi-xun Du & Hong JiangÂ

doi : 10.1038/s41401-023-01063-0

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α-MSH-catabolic enzyme prolylcarboxypeptidase in nucleus accumbens shell ameliorates stress susceptibility in mice through regulating synaptic plasticity

Qiao Deng, Shao-qi Zhang, Ping-fen Yang, Wan-ting Dong, Fang Wang, Li-hong Long & Jian-guo ChenÂ

doi : 10.1038/s41401-023-01074-x

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Functional characterization and in vitro pharmacological rescue of KCNQ2 pore mutations associated with epileptic encephalopathy

Gui-mei Yang, Fu-yun Tian, Yan-wen Shen, Chuan-yan Yang, Hui Yuan, Ping Li & Zhao-bing GaoÂ

doi : 10.1038/s41401-023-01073-y

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(+)-Borneol enantiomer ameliorates epileptic seizure via decreasing the excitability of glutamatergic transmission

Yu Wang, Xiao-yun Qiu, Jia-ying Liu, Bei Tan, Fei Wang, Min-juan Sun, Xu-hong Jiang, Xu-ming Ji, Ceng-lin Xu, Yi Wang & Zhong ChenÂ

doi : 10.1038/s41401-023-01075-w

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Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition

Kai-li Hao, Qiao-cheng Zhai, Yue Gu, Yue-qiu Chen, Ya-ning Wang, Rui Liu, Shi-ping Yan, Ying Wang, Yu-fang Shi, Wei Lei, Zhen-ya Shen, Ying Xu & Shi-jun HuÂ

doi : 10.1038/s41401-023-01059-w

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Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs

Xiao-kang Zhao, Meng-meng Zhu, Sheng-nan Wang, Ting-ting Zhang, Xiao-ning Wei, Cheng-yi Wang, Juan Zheng, Wen-ya Zhu, Mei-xiu Jiang, Suo-wen Xu, Xiao-xiao Yang, Ya-jun Duan, Bu-chun Zhang, Ji-hong Han, Qing R. Miao, Hao Hu & Yuan-li ChenÂ

doi : 10.1038/s41401-023-01077-8

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Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β

Shao-ru Chen, Zheng-qing Li, Jun Xu, Mo-yu Ding, Ya-ming Shan, Yung-chi Cheng, Gao-xiao Zhang, Ye-wei Sun, Yu-qiang Wang & Ying WangÂ

doi : 10.1038/s41401-023-01067-w

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TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis

Wen-ji Yang, Fang-hui Han, Yi-pei Gu, Hui Qu, Jia Liu, Jian-hua Shen & Ying LengÂ

doi : 10.1038/s41401-023-01081-y

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GPR84 regulates pulmonary inflammation by modulating neutrophil functions

Si-wei Wang, Qing Zhang, Dan Lu, You-chen Fang, Xiao-ci Yan, Jing Chen, Zhi-kan Xia, Qian-ting Yuan, Lin-hai Chen, Yang-ming Zhang, Fa-jun Nan & Xin XieÂ

doi : 10.1038/s41401-023-01080-z

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Astragalin ameliorates renal injury in diabetic mice by modulating mitochondrial quality control via AMPK-dependent PGC1α pathway

Meng-yao Sun, Hui-jing Ye, Chen Zheng, Zi-jie Jin, Yan Yuan & Hong-bo WengÂ

doi : 10.1038/s41401-023-01064-z

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Atranorin inhibits NLRP3 inflammasome activation by targeting ASC and protects NLRP3 inflammasome-driven diseases

Hao-yu Wang, Xi Lin, Guan-gen Huang, Rong Zhou, Shu-yue Lei, Jing Ren, Kai-rong Zhang, Chun-lan Feng, Yan-wei Wu & Wei TangÂ

doi : 10.1038/s41401-023-01054-1

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Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics

Wen-si Zhao, Kai-feng Chen, Man Liu, Xing-long Jia, Yu-qi Huang, Bing-bing Hao, Hao Hu, Xiao-yan Shen, Qiang Yu & Min-jia TanÂ

doi : 10.1038/s41401-023-01072-z

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Aspirin triggers ferroptosis in hepatocellular carcinoma cells through restricting NF-κB p65-activated SLC7A11 transcription

Yu-fei Wang, Jin-yan Feng, Li-na Zhao, Man Zhao, Xian-fu Wei, Yu Geng, Hong-feng Yuan, Chun-yu Hou, Hui-hui Zhang, Guo-wen Wang, Guang Yang & Xiao-dong ZhangÂ

doi : 10.1038/s41401-023-01062-1

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