Nature Reviews Drug Discovery




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Including African data in drug discovery and development

Clinton G. L. VealeAdrienne L. EdkinsKelly Chibale

doi : 10.1038/d41573-023-00088-8

Volume 22 Issue 7, July 2023

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RSV vaccines score landmark FDA approvals

Katie Kingwell

doi : 10.1038/d41573-023-00085-x

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FDA approves first-in-class NK3 receptor antagonist for hot flushes

Asher Mullard

doi : 10.1038/d41573-023-00084-y

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PD1 agonist antibody passes first phase II trial for autoimmune disease

Asher Mullard

doi : 10.1038/d41573-023-00087-9

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FDA approves first topical gene therapy

Asher Mullard

doi : 10.1038/d41573-023-00095-9

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FDA approves new antibiotic combination for drug-resistant pneumonia

Asher Mullard

doi : 10.1038/d41573-023-00096-8

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Upcoming market catalysts in Q3 2023

Shad Jabbar

doi : 10.1038/d41573-023-00101-0

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First-in-class versus best-in-class: an update for new market dynamics

Lindsay Spring, Kunle Demuren, Michael Ringel & John Wu

doi : 10.1038/d41573-023-00048-2

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A ROS-mediated resistance pathway to anticancer drugs

Alex Eccleston

doi : 10.1038/d41573-023-00094-w

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Inhibiting Sec61-mediated protein translocation

Sarah Crunkhorn

doi : 10.1038/d41573-023-00086-w

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Docking on SERT reveals new inhibitors

M. Teresa Villanueva

doi : 10.1038/d41573-023-00089-7

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PI3K activator taps route to regeneration

Katie Kingwell

doi : 10.1038/d41573-023-00097-7

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A new antibiotic for A. baumannii

Sarah Crunkhorn

doi : 10.1038/d41573-023-00090-0

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Improving leukaemia treatment with bispecific antibodies

Sarah Crunkhorn

doi : 10.1038/d41573-023-00091-z

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Understanding sphingosine-1-phosphate transport

Sarah Crunkhorn

doi : 10.1038/d41573-023-00092-y

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Hypoimmune iPSCs escape immune detection

Sarah Crunkhorn

doi : 10.1038/d41573-023-00093-x

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Amplifying gene expression with RNA-targeted therapeutics

Olga Khorkova, Jack Stahl, Aswathy Joji, Claude-Henry Volmar & Claes WahlestedtÂ

doi : 10.1038/s41573-023-00704-7

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Deuterium in drug discovery: progress, opportunities and challenges

Rita Maria Concetta Di Martino, Brad D. Maxwell & Tracey PiraliÂ

doi : 10.1038/s41573-023-00703-8

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Accelerating antiviral drug discovery: lessons from COVID-19

Annette von Delft, Matthew D. Hall, Ann D. Kwong, Lisa A. Purcell, Kumar Singh Saikatendu, Uli Schmitz, John A. Tallarico & Alpha A. LeeÂ

doi : 10.1038/s41573-023-00692-8

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