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The Exposome Applied: A Step toward Defining the Totality of Environmental Exposures in Asthma
Fenna C. M. Sillé 1, Meredith McCormack 1,2, and Thomas Hartung 1,3
Evolution of the Gain-of-Function MUC5B Promoter Variant
David A. Schwartz 1,2, Rachel Z. Blumhagen 3, and Tasha E. Fingerlin 3
Toward a Broader Characterization of Macro- and Microcirculatory Uncoupling in Cardiogenic Shock
Patrick R. Lawler 1,2 and Sean van Diepen 3
A New Era for Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator Modulator Trials in Infants
Claire E. Wainwright
A Problem for Generations: Impact of E-Cigarette Type on Immune Homeostasis
Lauren Sullivan 1,2 and Laura E. Crotty Alexander 1,2
Idiopathic Pulmonary Fibrosis Genetic Risk Factors, Function, and Mechanisms? The Concepts Are Starting to Gel
Catherine A. Bonham and Imre Noth
Rare Genetic Variants Provide Protection for Obstructive Sleep Apnea
Allan I. Pack and Brendan T. Keenan
Pharmacotherapy and Mortality in Chronic Obstructive Pulmonary Disease
David M.G. Halpin 1 and Fernando J. Martinez 2
Exposome Profiles and Asthma among French Adults
Alicia Guillien 1, Annabelle Bédard 2, Orianne Dumas 2, Julien Allegre 3, Nathalie Arnault 3, Audrey Bochaton 4, Nathalie Druesne-Pecollo 3, Dorothée Dumay 5, Léopold K. Fezeu 3, Serge Hercberg 3, Nicole Le Moual 2, Hugo Pilkington 5, Stéphane Rican 4, Guillaume Sit 2, Fabien Szabo de Edelenyi 3, Mathilde Touvier 3, Pilar Galan 3, Thierry Feuillet 3,5, Raphaëlle Varraso 2, and Valérie Siroux 1 ... Show less
A MUC5B Gene Polymorphism, rs35705950-T, Confers Protective Effects Against COVID-19 Hospitalization but Not Severe Disease or Mortality
Anurag Verma 1,2*, Jessica Minnier 3,4,5*, Emily S. Wan 6,7*, Jennifer E. Huffman 8, Lina Gao 4,5, Jacob Joseph 9,10, Yuk-Lam Ho 8, Wen-Chih Wu 11,12, Kelly Cho 8,13, Bryan R. Gorman 8, Nallakkandi Rajeevan 14,15, Saiju Pyarajan 8,16, Helene Garcon 8, James B. Meigs 17, Yan V. Sun 18,19, Peter D. Reaven 20,21, John E. McGeary 22,23, Ayako Suzuki 24,25, Joel Gelernter 26,27, Julie A. Lynch 28,29, Jeffrey M. Petersen 1,30, Seyedeh Maryam Zekavat 31,32, Pradeep Natarajan 16,32,33, Sharvari Dalal 1,30, Darshana N. Jhala 1,30, Mehrdad Arjomandi 34, Elise Gatsby 28, Kristine E. Lynch 28,35, Robert A. Bonomo 36, Matthew Freiberg 37, Gita A. Pathak 26,27, Jin J. Zhou 38,39, Curtis J. Donskey 40, Ravi K. Madduri 41, Quinn S. Wells 37,42,43, Rose D. L. Huang 8, Renato Polimanti 26,27, Kyong-Mi Chang 1, Katherine P. Liao 44, Philip S. Tsao 45, Peter W. F. Wilson 19,46, Adriana M. Hung 47, Christopher J. O’Donnell 48, John M. Gaziano 8, Richard L. Hauger 49,50, Sudha K. Iyengar 51,52‡, Shiuh-Wen Luoh 4,5‡, and the Million Veteran Program COVID-19 Science Initiative ... Show less
Performance of Early Capillary Refill Time Measurement on Outcomes in Cardiogenic Shock: An Observational, Prospective Multicentric Study
Hamid Merdji 1,2, Anais Curtiaud 1, Antoine Aheto 1, Antoine Studer 1, Veli-Pekka Harjola 3,4, Alexandra Monnier 1, Kevin Duarte 5, Nicolas Girerd 5, Marion Kibler 6, Hafid Ait-Oufella 7,8, Julie Helms 1,2, Alexandre Mebazaa 9,10, Bruno Levy 11, Antoine Kimmoun 11, and Ferhat Meziani 1,2,12 ... Show less
A Phase 3, Open-Label Study of Lumacaftor/Ivacaftor in Children 1 to Less Than 2 Years of Age with Cystic Fibrosis Homozygous for F508del-CFTR
Jonathan H. Rayment 1, Fadi Asfour 2, Margaret Rosenfeld 3, Mark Higgins 4, Lingyun Liu 4, Molly Mascia 4, Hildegarde Paz-Diaz 4, Simon Tian 4, Rachel Zahigian 4, and Susanna A. McColley 5,6; for the VX16-809-122 Study Group
Biomarkers of Airway Immune Homeostasis Differ Significantly with Generation of E-Cigarettes
Elise Hickman 1,2, Alexis Payton 1,3,4, Parker Duffney 1,2, Heather Wells 1, Agathe S. Ceppe 5, Stephanie Brocke 1,2, Aleah Bailey 1,2, Meghan E. Rebuli 1,2, Carole Robinette 1, Brian Ring 1, Julia E. Rager 1,2,3,4, Neil E. Alexis 1, and Ilona Jaspers 1,2,4 ... Show less
Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis
Raphael Borie 1*, Jonathan Cardwell 2*, Iain R. Konigsberg 2*, Camille M. Moore 3,4, Weiming Zhang 3, Sarah K. Sasse 5, Fabienne Gally 2,6, Evgenia Dobrinskikh 2,7, Avram Walts 2, Julie Powers 2, Janna Brancato 2, Mauricio Rojas 8, Paul J. Wolters 9, Kevin K. Brown 5, Timothy S. Blackwell 10, Tomoko Nakanishi 11, J. Brent Richards 11, Anthony N. Gerber 2,5,6, Tasha E. Fingerlin 3,4,6, Norman Sachs 12, Sara L. Pulit 13, Zachary Zappala 13, David A. Schwartz 2,14‡, and Ivana V. Yang 2,15‡ ... Show less
Targeted Genome Sequencing Identifies Multiple Rare Variants in Caveolin-1 Associated with Obstructive Sleep Apnea
Jingjing Liang 1*, Heming Wang 2,3,4*, Brian E. Cade 2,3,4, Nuzulul Kurniansyah 2, Karen Y. He 1, Jiwon Lee 2, Scott A. Sands 2,3, Jennifer A. Brody 5, Han Chen 6,7, Daniel J. Gottlieb 2,3,8, Daniel S. Evans 9, Xiuqing Guo 10,11, Sina A. Gharib 12, Lauren Hale 13, David R. Hillman 14, Pamela L. Lutsey 15, Sutapa Mukherjee 16,17, Heather M. Ochs-Balcom 18, Lyle J. Palmer 19, Shaun Purcell 2,3,4, Richa Saxena 2,3,4,20,21, Sanjay R. Patel 22, Katie L. Stone 9, Gregory J. Tranah 9, Eric Boerwinkle 5,23, Xihong Lin 24, Yongmei Liu 25, Bruce M. Psaty 5,26,27, Ramachandran S. Vasan 28,29,30,31, Ani Manichaikul 32,33, Stephen S. Rich 32, Jerome I. Rotter 9,10, Tamar Sofer 2,3,24, Susan Redline 2,3‡, Xiaofeng Zhu 1‡, and TOPMed Sleep Working Group ... Show less
A Case of Catathrenia Captured on Polysomnography with Audio–Visual Recording
Anusha Devarajan , Miranda R. Roderick , Bernie W. Miller , and Chad M. Ruoff
The Recruitment-to-Inflation Ratio Is Correlated with EIT-Derived Collapse and Overdistention in COVID-19 ARDS
Tommaso Pettenuzzo 1*, Nicolò Sella 1*, Giulia Lorenzoni 2, Alvise Calore 1,2, Francesco Zarantonello 1, Giulio Andreatta 1,2, Alessandro De Cassai 1, Dario Gregori 2, Annalisa Boscolo 1‡, and Paolo Navalesi 1,2
The MI-PICC Score: A Risk-Prediction Model for PICC-associated Complications in the ICU
Sushant Govindan 1,2*, Megan E. O’Malley 3, Scott A. Flanders 4, and Vineet Chopra 3,4,5
Cognitive Dysfunction in Patients with Pulmonary Hypertension
Ping Yuan 1*, Jinling Li 1*, Jianhui Liu 2, Hongting Liu 1, Sugang Gong 1, Lan Wang 1, Jinming Liu 1, Congcong Li 2, Yi Wang 3, Xiaohuan Xia 2‡, and Jialin C. Zheng 2‡
Idiopathic Pulmonary Fibrosis Update: Reconciliation with Hypersensitivity Pneumonitis Guidelines Required?
Onofre Moran-Mendoza *
Progressive Pulmonary Fibrosis: Should the Timelines Be Taken Out of the Definition?
Vincent Cottin 1,2*, Kevin K. Brown 3, Kevin R. Flaherty 4, Athol U. Wells 5
Progressive Pulmonary Fibrosis: Putting the Cart Before the Horse
Kerri A. Johannson 1*, Martin Kolb 2, Jolene H. Fisher 3, and Simon L.F. Walsh 4
Comment on Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults
Mary Beth Scholand 1* and Athol U. Wells 2
Anti-acid Therapies in Idiopathic Pulmonary Fibrosis: Premature to Dismiss?
Louise E. Crowley 1*, Andrew Wilson 2, and David R. Thickett 1
Reply to Moran-Mendoza: Idiopathic Pulmonary Fibrosis Update. Reconciliation with Hypersensitivity Pneumonitis Guidelines Required?
Ganesh Raghu 1*, Luca Richeldi 2, Carey C. Thomson 3, Martine Remy-Jardin 4, and Kevin C. Wilson 5
Statistical Concern Regarding the Relationship of Change in Mucus Plug Score with Airflow Over Time
Tokunori Ikeda 1 and Yusuke Tomita 2*
Reply to Ikeda and Tomita
Monica Tang 1, David T. Mauger 2, John V. Fahy 1*, and Eleanor M. Dunican 3,4
Erratum: COVID-19 and Risk of Oxygen-Dependent Chronic Respiratory Failure: A National Cohort Study
