American Journal of Respiratory and Critical Care Medicine




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October 1 Highlight

doi : 10.1164/rccm.2066Pxxiv  

Volume 206, Issue 7 | October 1 2022

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When Health Disparities Hit Home: Redlining Practices, Air Pollution, and Asthma

Sonali Bose 1,2, Jaime Madrigano 3, and Nadia N. Hansel 2,3

doi : 10.1164/rccm.202206-1063ED  

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Use of Computed Tomography Lung Densitometry as an Outcome Measure for Emphysema Progression: The Case of Losartan

Marc Miravitlles 1 and Antonio Anzueto 2

doi : 10.1164/rccm.202205-0927ED

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Untangling Lower Airway Dysbiosis in Critically Ill Patients with COVID-19

Clea R. Barnett and Leopoldo N. Segal

doi : 10.1164/rccm.202206-1074ED

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Pulmonary Vasculopathy in COVID-19 Acute Respiratory Distress Syndrome: A Step Closer to the Full Picture

V. Eric Kerchberger 1,2 and Julie A. Bastarache 1,3,4

doi : 10.1164/rccm.202205-1019ED

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The Optimal Glycemic Control in Patients with Diabetes in the ICU: Where Is the Sweet Spot?

Jeroen Hermanides 1 and Moritoki Egi 2

doi : 10.1164/rccm.202206-1045ED  

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Deep Learning–based Classification of Fibrotic Lung Disease: Can Computer Vision See the Future?

Bina Choi 1,2 and Samuel Y. Ash 1,2

doi : 10.1164/rccm.202206-1036ED  

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The Value of Chest Radiography in Tuberculosis Preventive Treatment Screening in Children and Adolescents

Ben J. Marais 1,2 and Stephen M. Graham 2,3,4

doi : 10.1164/rccm.202205-1023ED  

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Impact of Sex and Gender on Autoimmune Lung Disease: Opportunities for Future Research: NHLBI Working Group Report

Elizabeth R. Volkmann 1, Jill Siegfried 2, Tim Lahm 3, Corey E. Ventetuolo 4, Stephen C. Mathai 5, Virginia Steen 6, Erica L. Herzog 7, Rebecca Shansky 8, Montserrat C. Anguera 9, Sonye K. Danoff 5, Jon T. Giles 10, Yvonne C. Lee 11, Wonder Drake 12, Lisa A. Maier 13, Marrah Lachowicz-Scroggins 14, Heiyoung Park 15, Koyeli Banerjee 16, Josh Fessel 16, Lora Reineck 16, Louis Vuga 16, Elliott Crouser 17, and Carol Feghali-Bostwick 18

doi : 10.1164/rccm.202112-2746PP  

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Historical Redlining Impacts Contemporary Environmental and Asthma-related Outcomes in Black Adults

Alexander J. Schuyler 1,2 and Sally E. Wenzel 1,2

doi : 10.1164/rccm.202112-2707OC

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Clinical Trial of Losartan for Pulmonary Emphysema: Pulmonary Trials Cooperative Losartan Effects on Emphysema Progression Clinical Trial

Robert A. Wise 1, Janet T. Holbrook 2, Robert H. Brown 1, Gerard J. Criner 3, Mark T. Dransfield 4, Jiaxian He 2, Robert J. Henderson 2, David A. Kaminsky 5, Robert J. Kaner 6, Stephen C. Lazarus 7, Barry J. Make 8, Meredith C. McCormack 1, Enid R. Neptune 1, and Loretta G. Que 9;

doi : 10.1164/rccm.202201-0206OC   

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Lung Microbiota of Critically Ill Patients with COVID-19 Are Associated with Nonresolving Acute Respiratory Distress Syndrome

Robert F. J. Kullberg 1, Justin de Brabander 1*, Leonoor S. Boers 2,3*, Jason J. Biemond 1, Esther J. Nossent 4, Leo M. A. Heunks 5, Alexander P. J. Vlaar 2,3, Peter I. Bonta 4, Tom van der Poll 1,6, JanWillem Duitman 4,7, Lieuwe D. J. Bos 2,3,4‡, and W. Joost Wiersinga 1,6‡;

doi : 10.1164/rccm.202202-0274OC  

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Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and Acute Respiratory Distress Syndrome

Julian A. Villalba 1,2*‡, Caroline F. Hilburn 1,2*, Michelle A. Garlin 3,4, Grant A. Elliott 5, Yijia Li 6, Keiko Kunitoki 7,8, Sergio Poli 9, George A. Alba 10, Emilio Madrigal 1,2, Manuel Taso 11, Melissa C. Price 12, Alexis J. Aviles 1, Milagros Araujo-Medina 1,13, Liana Bonanno 1,2, Baris Boyraz 1,2, Samantha N. Champion 1,2,14,15, Cynthia K. Harris 1,2, Timothy L. Helland 1,2, Bailey Hutchison 1,2, Soma Jobbagy 1,2, Michael S. Marshall 1,2, Daniel J. Shepherd 1,2, Jaimie L. Barth 1, Yin P. Hung 1,2, Amy Ly 1,2, Lida P. Hariri 1,2,10, Sarah E. Turbett 1,2,16, Virginia M. Pierce 1,2,17, John A. Branda 1,2, Eric S. Rosenberg 1,2,16, Javier Mendez-Pena 1, Ivan Chebib 1,2, Ivy A. Rosales 1,2,13, Rex N. Smith 1,2,13, Miles A. Miller 3, Ivan O. Rosas 18, Charles C. Hardin 10, Lindsey R. Baden 6, Benjamin D. Medoff 10, Robert B. Colvin 1,2,13, Brent P. Little 12,19, James R. Stone 1,2§, Mari Mino-Kenudson 1,2§, and Angela R. Shih 1,2§

doi : 10.1164/rccm.202109-2150OC

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The Effect of a Liberal Approach to Glucose Control in Critically Ill Patients with Type 2 Diabetes: A Multicenter, Parallel-Group, Open-Label Randomized Clinical Trial

Alexis P. Poole 1,2,3, Mark E. Finnis 1,2,3,4, James Anstey 4,5, Rinaldo Bellomo 3,4,6, Shailesh Bihari 7, Vishwanath Biradar 8, Sarah Doherty 5, Glenn Eastwood 3,4,6, Simon Finfer 9, Craig J. French 4,10, Simon Heller 11, Michael Horowitz 12,13, Palash Kar 1,2, Peter S. Kruger 14,15, Matthew J. Maiden 1,2,16, Johan MÃ¥rtensson 17, Colin J. McArthur 18, Shay P. McGuinness 19, Paul J. Secombe 3,20, Antony E. Tobin 4,21, Andrew A. Udy 3,22, Paul J. Young 3,4,23,24, and Adam M. Deane 4,5;

doi : 10.1164/rccm.202202-0329OC

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Deep Learning–based Outcome Prediction in Progressive Fibrotic Lung Disease Using High-Resolution Computed Tomography

Simon L. F. Walsh 1, John A. Mackintosh 2, Lucio Calandriello 3, Mario Silva 4, Nicola Sverzellati 4, Anna Rita Larici 3, Stephen M. Humphries 5, David A. Lynch 5, Helen E. Jo 6, Ian Glaspole 7, Christopher Grainge 8, Nicole Goh 9,10,11, Peter M. A. Hopkins 2,12, Yuben Moodley 13, Paul N. Reynolds 14, Christopher Zappala 15, Gregory Keir 16, Wendy A. Cooper 17,18, Annabelle M. Mahar 17, Samantha Ellis 19, Athol U. Wells 1,20, and Tamera J. Corte 6

doi : 10.1164/rccm.202112-2684OC

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The Contribution of Chest Radiography to the Clinical Management of Children Exposed to Tuberculosis

Chuan-Chin Huang 1,2*, Qi Tan 2,3*, Mercedes C. Becerra 1,2, Roger Calderon 4, Silvia S. Chiang 5,6, Carmen Contreras 4, Leonid Lecca 2,4, Judith Jimenez 4, Carlos M. Perez-Velez 7,8, Claudia L. Roya-Pabon 7, Rosa Yataco 4, Hai Xu 9, Zibiao Zhang 1, and Megan Murray 1,2,10

doi : 10.1164/rccm.202202-0259OC  

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Endotracheal Xanthoma Disseminatum

Jessica McLaughlin 1, Dana Martin 2, Javeryah Safi 3, Ray W. Shepherd 1, and Samira Shojaee 1

doi : 10.1164/rccm.202202-0285IM

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Tracheobronchial Smooth Muscle Atrophy and Separation

Prince Ntiamoah 1, Adam Fawaz 1, Atul C. Mehta 2, and Thomas R. Gildea 2

doi : 10.1164/rccm.202202-0258IM

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Genome-wide Enrichment of TERT Rare Variants in Idiopathic Pulmonary Fibrosis Patients of Latino Ancestry

David Zhang 1, Qi Li 1, Gundula Povysil 1, Chad A. Newton 2, Toby M. Maher 3,4, Philip L. Molyneaux 4, Imre Noth 5, Fernando J. Martinez 6, Ganesh Raghu 7, Jamie L. Todd 8, Scott M. Palmer 8, Adam Platt 9, Slavé Petrovski 9,10, David B. Goldstein 1, and Christine Kim Garcia 1* ... Show less

doi : 10.1164/rccm.202203-0622LE

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Polarization-Sensitive Endobronchial Optical Coherence Tomography for Microscopic Imaging of Fibrosis in Interstitial Lung Disease

Sreyankar Nandy 1,2, Sarita R. Berigei 1, Colleen M. Keyes 1,2, Ashok Muniappan 1,2, Hugh G. Auchincloss 1,2, Michael Lanuti 1,2, Benjamin W. Roop 1, Angela R. Shih 1,2, Thomas V. Colby 3, Benjamin D. Medoff 1,2, Melissa J. Suter 1,2, Martin Villiger 1,2, and Lida P. Hariri 1,2*

doi : 10.1164/rccm.202112-2832LE

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A Novel Index to Predict the Failure of High-Flow Nasal Cannula in Patients with Acute Hypoxemic Respiratory Failure: A Pilot Study

Dongyu Chen 1,2 , Leo Heunks 3, Chun Pan 1, Jianfeng Xie 1, Haibo Qiu 1, Yi Yang 1*, and Ling Liu 1*‡

doi : 10.1164/rccm.202203-0561LE

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Upper and Lower Airway Dysanapsis and Airflow Obstruction among Older Adults

Benjamin M. Smith 1,2*, Andrew Wiemken 3, Eric A. Hoffman 4, Brendan T. Keenan 3, Norrina B. Allen 5, Alain G. Bertoni 6, David R. Jacobs Jr.7, Erin D. Michos 8, Karol E. Watson 9, Susan Redline 10, Richard J. Schwab 3, R. Graham Barr 1, and Susan R. Heckbert 11

doi : 10.1164/rccm.202202-0353LE

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Postvaccination Acute Exacerbations of Idiopathic Pulmonary Fibrosis?

Jin-Xian Huang 1 and James Cheng-Chung Wei 2,3,4,5*

doi : 10.1164/rccm.202204-0756LE

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Comments on COVID-19 Vaccination and Exacerbation of Idiopathic Pulmonary Fibrosis

Tianlun Kang 1, Xiujuan Hou 1, Chih-Wei Chen 2*, Yajing Xi 1, and James Cheng-Chung Wei 3,4,5,6*‡

doi : 10.1164/rccm.202205-0877LE

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COVID-19 mRNA Vaccines and Interstitial Lung Disease Exacerbation: Causation or Just a Temporal Association?

Solmaz Ehteshami-Afshar and Rishi Raj *

doi : 10.1164/rccm.202205-0902LE  

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Reply to Huang and Wei, Kang et al., and Ehteshami-Afshar and Raj

Giacomo Sgalla 1* and Luca Richeldi 2;

doi : 10.1164/rccm.202205-0850LE

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Comments on Air Pollutant Exposures and COVID-19 Severity and Mortality: Some Concerns on Methodology

Hui-Yuan Chen 1*, Renin Chang 2*, and James Cheng-Chung Wei 1,3,4,5‡

doi : 10.1164/rccm.202206-1032LE

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Reply to Chen et al.

Zhanghua Chen 1, Margo A. Sidell 2, Frank D. Gilliland 1, and Anny H. Xiang 2*

doi : 10.1164/rccm.202206-1148LE

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Susceptibility of Patients with Asthma to a Poor Outcome of COVID-19

Carl Persson *

doi : 10.1164/rccm.202205-0978LE

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