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Vascular supply of the optic nerve head: implications for optic disc ischaemia
Anthony Arnold
doi : 10.1136/bjo-2022-322254
The vascular supply of the optic nerve head is complex and remains incompletely delineated. Over the past 50 years, various investigators have attempted to clarify the relative contributions of the choroid, the short posterior ciliary arteries and the central retinal artery to the vascular beds of the inner retinal, prelaminar, laminar and retrolaminar segments of the nerve head.Â
Pathologic myopia: advances in imaging and the potential role of artificial intelligence
Yong Li, Li-Lian Foo, Chee Wai Wong, Jonathan Li, Quan V Hoang, Leopold Schmetterer, Daniel S W Ting, Marcus Ang
Microsporidia-induced stromal keratitis: a new cause of presumed immune stromal (interstitial) keratitis
Amrita Mohanty, Himansu Sekhar Behera, Manas Ranjan Barik, Amanjot Kaur, Savitri Sharma, Sujata Das, Merle Fernandes, Sailendra Panda, Srikant K Sahu
doi : 10.1136/bjophthalmol-2021-319784
Background and objective To describe the clinical features, diagnosis and management of immune stromal keratitis/interstitial keratitis (IK) associated with microsporidial epithelial keratitis.
Conjunctival ultraviolet autofluorescence area decreases with age and sunglasses use
Gareth Lingham, Jason Kugelman, Jason Charng, Samantha SY Lee, Seyhan Yazar, Charlotte M McKnight, Minas T Coroneo, Robyn M Lucas, Holly Brown, Louis J Stevenson, David A Mackey, David Alonso-Caneiro
doi : 10.1136/bjophthalmol-2021-320284
Background Conjunctival ultraviolet autofluorescence (CUVAF) is a method of detecting conjunctival damage related to ultraviolet radiation exposure. In cross-sectional studies, CUVAF area is positively associated with self-reported time spent outdoors and pterygium and negatively associated with myopia; however, longitudinal studies are scarce.
Histopathology-guided management of ocular surface squamous neoplasia with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy
Raksha Rao, Santosh G Honavar, Sumeet Lahane, Kaustubh Mulay, Vijayanand Palkonda Reddy
doi : 10.1136/bjophthalmol-2021-319201
Background/aim To evaluate the safety and efficacy of ruthenium-106 (Ru-106) plaque brachytherapy in managing invasive ocular surface squamous neoplasia (OSSN).
Automated histopathological evaluation of pterygium using artificial intelligence
Jong Hoon Kim, Young Jae Kim, Yeon Jeong Lee, Joon Young Hyon, Sang Beom Han, Kwang Gi Kim
doi : 10.1136/bjophthalmol-2021-320141
Purpose This study aimed to evaluate the efficacy of a new automated method for the evaluation of histopathological images of pterygium using artificial intelligence.
Universal architecture of corneal segmental tomography biomarkers for artificial intelligence-driven diagnosis of early keratoconus
Gairik Kundu, Rohit Shetty, Pooja Khamar, Ritika Mullick, Sneha Gupta, Rudy Nuijts, Abhijit Sinha Roy
doi : 10.1136/bjophthalmol-2021-319309
Aims To develop a comprehensive three-dimensional analyses of segmental tomography (placido and optical coherence tomography) using artificial intelligence (AI).
Progression of myopia in teenagers and adults: a nationwide longitudinal study of a prevalent cohort
Alexandre Ducloux, Simon Marillet, Pierre Ingrand, Mark A Bullimore, Rupert R A Bourne, Nicolas Leveziel
doi : 10.1136/bjophthalmol-2021-319568
Background The prevalence of myopia is increasing worldwide. The purpose of this study was to evaluate the progression of myopia in teenagers and adults in France.
Macular and submacular choroidal microvasculature in patients with primary open-angle glaucoma and high myopia
Fengbin Lin, Zhen Qiu, Fei Li, Yu Chen, Yuying Peng, Meiling Chen, Yunhe Song, Jian Xiong, Weijing Cheng, Yuhong Liu, Mingkui Tan, Xiulan Zhang, Robert Weinreb
doi : 10.1136/bjophthalmol-2021-319557
Aims To characterise the influence of primary open-angle glaucoma (POAG) and high myopia (HM) on the macular and choroidal capillary density (CD).
Long-term reproducibility of optical coherence tomography angiography in healthy and stable glaucomatous eyes
Takashi Nishida, Sasan Moghimi, Huiyuan Hou, James A Proudfoot, Aimee C Chang, Ryan Caezar C David, Alireza Kamalipour, Nevin El-Nimri, Jasmin Rezapour, Christopher Bowd, Linda M Zangwill, Robert N Weinreb
doi : 10.1136/bjophthalmol-2021-320034
Background/aims To assess and compare long-term reproducibility of optic nerve head (ONH) and macula optical coherence tomography angiography (OCTA) vascular parameters and optical coherence tomography (OCT) thickness parameters in stable primary open-angle glaucoma (POAG), glaucoma suspect and healthy eyes.
Handheld chromatic pupillometry can accurately and rapidly reveal functional loss in glaucoma
Raymond P Najjar, A V Rukmini, Maxwell T Finkelstein, Simon Nusinovici, Baskaran Mani, Monisha Esther Nongpiur, Shamira Perera, Rahat Husain, Tin Aung, Dan Milea
doi : 10.1136/bjophthalmol-2021-319938
Background/aims Early detection and treatment of glaucoma can delay vision loss. In this study, we evaluate the performance of handheld chromatic pupillometry (HCP) for the objective and rapid detection of functional loss in glaucoma.
Primary slow-coagulation transscleral cyclophotocoagulation laser treatment for medically recalcitrant neovascular glaucoma
Mohamed M Khodeiry, Alison J Lauter, Mohamed S Sayed, Ying Han, Richard K Lee
doi : 10.1136/bjophthalmol-2021-319757
Aims To report treatment outcomes of slow-coagulation continuous-wave transscleral cyclophotocoagulation (TSCPC) as an initial surgical intervention in patients with neovascular glaucoma (NVG).
Prevalence, ethnic differences and risk factors of primary angle-closure glaucoma in a multiethnic Chinese adult population: the Yunnan Minority Eye Study
Ying Wang, Qing Cun, Jun Li, Wei Shen, Wen-Yan Yang, Yi-Jin Tao, Zhi-Qiang Niu, Ying Zhang, Hua Zhong, Chen-Wei Pan
doi : 10.1136/bjophthalmol-2021-320241
Purpose To describe the prevalence and risk factors of primary angle-closure glaucoma (PACG) and to explore nationality difference in Chinese.
Prevalence rates of cataract and cataract surgery in elderly Chinese people living in suburban Shanghai: the Pujiang Cataract Cohort Study
Shaohua Zhang, Jiahui Chen, Fan Yang, Binxin Xu, Yating Tang, Yi Lu
doi : 10.1136/bjophthalmol-2021-319991
Purpose To estimate the prevalence rates of cataract and cataract surgery in suburban Shanghai, China.
Gonioscopy-assisted transluminal trabeculotomy is an effective surgical treatment for uveitic glaucoma
Avner Belkin, Yuri Valere Chaban, Derek Waldner, Saba Samet, Iqbal Ike K Ahmed, Patrick Gooi, Matthew B Schlenker
doi : 10.1136/bjophthalmol-2021-320270
Background To assess the efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) in uveitic glaucoma (UG).
Analysis of the pachychoroid phenotype in an Asian population: methodology and baseline study population characteristics
Wendy Meihua Wong, Wu Sun, Chinmayi Vyas, Angie Hon Chi Fong, Caroline K Chee, Xin Yi Su, Kelvin YC Teo, Chui Ming Gemmy Cheung
doi : 10.1136/bjo-2022-322457
Aim To describe the clinical characteristics in a cohort of patients with the pachychoroid phenotype and to evaluate the association of ocular and systemic factors with type of complications observed.
Evaluation of retinal nerve fibre layer thickness as a possible measure of diabetic retinal neurodegeneration in the EPIC-Norfolk Eye Study
Sidra Zafar, Kristen A Staggers, Jie Gao, Yao Liu, Praveen J Patel, Paul J Foster, Benjamin J Frankfort, Michael Abramoff, Charles G Minard, Alasdair Warwick, Anthony P Khawaja, Roomasa Channa
doi : 10.1136/bjophthalmol-2021-319853
Background/aims Markers to clinically evaluate structural changes from diabetic retinal neurodegeneration (DRN) have not yet been established. To study the potential role of peripapillary retinal nerve fibre layer (pRNFL) thickness as a marker for DRN, we evaluated the relationship between diabetes, as well as glycaemic control irrespective of diabetes status and pRNFL thickness.
Nationwide inventory on retinopathy of prematurity screening in the Netherlands
Kasia Trzcionkowska, Jacqueline U Termote, Stefan Böhringer, Arlette J van Sorge, Nicoline Schalij-Delfos
doi : 10.1136/bjophthalmol-2021-319929
Purpose Provide up-to-date insight in incidence of retinopathy of prematurity (ROP), logistics of screening and treatment in the Netherlands and influence of the new national ROP guideline in which more stringent screening criteria were implemented and the early treatment for ROP criteria (ETROP) were emphasised.
Temporal trends in the epidemiology of childhood severe visual impairment and blindness in the UK
Lucinda J Teoh, Ameenat Lola Solebo, Jugnoo S Rahi
doi : 10.1136/bjophthalmol-2021-320119
Background/aims Understanding temporal trends in childhood visual disability is necessary for planning and evaluating clinical services and health policies. We investigate the changing epidemiology of severe visual impairment (SVI) and blindness (BL) in children in the UK in the 21st century.
Worldwide outcomes of nasal transposition of the split lateral rectus muscle for strabismus associated with 3rd-nerve palsy
Ankoor S Shah, Mary-Magdalene Ugo Dodd, Birsen Gokyigit, Birgit Lorenz, Erick Laurent, Mohammad Ali Ayaz Sadiq, Chong-Bin Tsai, Nicolas Gravier, Mitra Goberville, Sotirios Basiakos, David Zurakowski, Linda R Dagi
doi : 10.1136/bjophthalmol-2021-319667
Background/aims To determine success rate and complications associated with nasal transposition of the split lateral rectus muscle (NTSLR) for treating strabismus from 3rd-nerve palsy.
Determining posterior vitreous structure by analysis of images obtained by AI-based 3D segmentation and ultrawidefield optical coherence tomography
Kyoko Ohno-Matsui, Hiroyuki Takahashi, Zaixing Mao, Noriko Nakao
doi : 10.1136/bjophthalmol-2021-320131
Aims To determine the three-dimensional (3D) structure of the vitreous fluid including the posterior precortical vitreous pockets (PPVP), Cloquet’s canal and cisterns in healthy subjects by AI-based segmentation of the vitreous of swept-source optical coherence tomography (OCT) images. In addition, to analyse the vitreous structures over a wide and deep area using ultrawidefield swept-source OCT (UWF-OCT).
Longitudinal associations of ocular biometric parameters with onset and progression of diabetic retinopathy in Chinese adults with type 2 diabetes mellitus
Wei Wang, Yifan Chen, Kun Xiong, Xia Gong, Xiaoling Liang, Wenyong Huang
doi : 10.1136/bjophthalmol-2021-320046
Aims To investigate the associations of ocular biometric parameters with incident diabetic retinopathy (DR), incident vision-threatening DR (VTDR) and DR progression.
Correction:Â Evolution of therapies for the corneal endothelium: past, present and future approaches
Correction:Â Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19
