Diabetes




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In This Issue of Diabetes 

Max Bingham, PhD

doi : 10.2337/db23-ti02

Volume 72, Issue 2

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Hyaluronan in Adipose Tissue, Metabolic Inflammation, and Diabetes: Innocent Bystander or Guilty Party? 

Krzysztof Drygalski; Simon Lecoutre; Karine Clément; Isabelle Dugail

doi : 10.2337/db22-0676

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Glucokinase Inhibition: A Novel Treatment for Diabetes? 

Maria S. Remedi; Colin G. Nichols

doi : 10.2337/db22-0731

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A Guide for Selection of Genetic Instruments in Mendelian Randomization Studies of Type 2 Diabetes and HbA1c: Toward an Integrated Approach 

Victoria Garfield; Antoine Salzmann; Stephen Burgess; Nish Chaturvedi

doi : 10.2337/db22-0110

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Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo ?-Cell Imaging and Islet-Specific Therapies 

Zheng Guo; Devi Kasinathan; Chengfeng Merriman; Maki Nakayama; Hua Li; Huilin Li; Cheng Xu; G. William Wong; Liping Yu; Maria L. Golson; Dax Fu

doi : 10.2337/db22-0477

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Profound Sensitivity of the Liver to the Direct Effect of Insulin Allows Peripheral Insulin Delivery to Normalize Hepatic but Not Muscle Glucose Uptake in the Healthy Dog 

Guillaume Kraft; Katie C. Coate; Marta Smith; Ben Farmer; Melanie Scott; Jon Hastings; Alan D. Cherrington; Dale S. Edgerton

doi : 10.2337/db22-0471

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N-end Rule–Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage 

Jiesi Xu; Zhenglong Liu; Jianxin Zhang; Siyu Chen; Wei Wang; Xuefan Zhao; Mei Zhen; Xun Huang

doi : 10.2337/db22-0362

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Impaired Diurnal Pattern of Meal Tolerance and Insulin Sensitivity in Type 2 Diabetes: Implications for Therapy 

Yogesh Yadav; Davide Romeres; Claudio Cobelli; Chiara Dalla Man; Rickey Carter; Ananda Basu; Rita Basu

doi : 10.2337/db22-0238

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Prostaglandin PGE2 Receptor EP4 Regulates Microglial Phagocytosis and Increases Susceptibility to Diet-Induced Obesity 

Anzela Niraula; Rachael D. Fasnacht; Kelly M. Ness; Jeremy M. Frey; Sophia A. Cuschieri; Mauricio D. Dorfman; Joshua P. Thaler

doi : 10.2337/db21-1072

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Sex Differences in Adipose Tissue Distribution Determine Susceptibility to Neuroinflammation in Mice With Dietary Obesity 

Alexis M. Stranahan; De-Huang Guo; Masaki Yamamoto; Caterina M. Hernandez; Hesam Khodadadi; Babak Baban; Wenbo Zhi; Yun Lei; Xinyun Lu; Kehong Ding; Carlos M. Isales

doi : 10.2337/db22-0192

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An Early Islet Transcriptional Signature Is Associated With Local Inflammation in Autoimmune Diabetes 

Alan G. Derr; Adediwura Arowosegbe; Basanthi Satish; Sambra D. Redick; Natasha Qaisar; Zhiru Guo; Emma Vanderleeden; Melanie I. Trombly; Christina E. Baer; David M. Harlan; Dale L. Greiner; Manuel Garber; Jennifer P. Wang

doi : 10.2337/db22-0521

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GC-Globulin/Vitamin D–Binding Protein Is Required for Pancreatic ?-Cell Adaptation to Metabolic Stress 

Katrina Viloria; Daniela Nasteska; Julia Ast; Annie Hasib; Federica Cuozzo; Silke Heising; Linford J.B. Briant; Martin Hewison; David J. Hodson

doi : 10.2337/db22-0326

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Diametrical Effects of Glucose Levels on Microvascular Permeability of Peripheral Nerves in Patients With Type 2 Diabetes With and Without Diabetic Neuropathy 

Christoph M. Mooshage; Lukas Schimpfle; Zoltan Kender; Julia Szendroedi; Sabine Heiland; Peter Nawroth; Martin Bendszus; Stefan Kopf; Felix T. Kurz; Johann M.E. Jende

doi : 10.2337/db22-0548

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Dorzagliatin, a Dual-Acting Glucokinase Activator, Increases Insulin Secretion and Glucose Sensitivity in Glucokinase Maturity-Onset Diabetes of the Young and Recent-Onset Type 2 Diabetes 

Elaine Chow; Ke Wang; Cadmon K.P. Lim; Sandra T.F. Tsoi; Baoqi Fan; Emily Poon; Andrea O.Y. Luk; Ronald C.W. Ma; Ele Ferrannini; Andrea Mari; Li Chen; Juliana C.N. Chan

doi : 10.2337/db22-0708

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Erratum. Obese Skeletal Muscle–Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome. Diabetes 2022;71:2256–2271 

Ting Yao; Hongmei Yan; Xiaopeng Zhu; Qiongyue Zhang; Xingyu Kong; Shanshan Guo; Yonghao Feng; Hui Wang; Yinghui Hua; Jing Zhang; Steven D. Mittelman; Peter Tontonoz; Zhenqi Zhou; Tiemin Liu; Xingxing Kong

doi : 10.2337/db23-er02a

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