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Gut microbiota, key to unlocking the door of diabetic kidney disease
Peipei Wang, Ting Wang, Xuejun Zheng, Wen Cui, Jin Shang, Zhanzheng Zhao
doi : 10.1111/nep.13874
NephrologyVolume 26, Issue 8 p. 641-649
This review discusses the influence of gut microbiota dysbiosis on diabetic kidney disease through metabolite profile changes and immune and inflammatory mechanisms. We also elaborate on the mechanism of dysbiosis in the onset and development of other kidney diseases.
Clinicopathological features of Chinese patients with B-cell lymphoproliferative disorders and kidney infiltration
Chi Yuen Cheung, Arthur H. C. Tang, Yuen Ting Wong, Gavin S. W. Chan, Sydney C. W. Tang
doi : 10.1111/nep.13876
NephrologyVolume 26, Issue 8 p. 650-658
Direct kidney involvement in B-cell lymphoproliferative disease is a rare disorder with only a few studies reported in Caucasian patients. The clinicopathological characteristics and outcome of this entity remain poorly described.
Safety and utility of kidney biopsy in patients with estimated glomerular filtration rate?<?30 ml/min/1.73?m2
Riyaz Ahmed Asad, Anna T. Valson, Vijayakumar Kavitha, Anila Korula, Anu Eapen, Grace Rebekah, Shibu Jacob, Harish Pathak, Suceena Alexander, Anjali Mohapatra, Vinoi George David, Santosh Varughese, Veerasamy Tamilarasi, Gopal Basu
doi : 10.1111/nep.13879
NephrologyVolume 26, Issue 8 p. 659-668
Kidney biopsy (KBx) is the gold standard for evaluation of kidney disease, but is associated with a higher risk of complications in patients with reduced glomerular filtration rate (GFR). We studied the safety and utility of KBx in patients with eGFR <30?ml/min/1.73?m2.
Impact of a kidney-specific disease-specific care certification program on the institutional performance indicators of hospitals caring for patients with chronic kidney disease: A?national data analysis
Chia-Ter Chao, Ching-I Chang, Pa-Chun Wang, Ching-Feng Chiang, Chia-Pei Chen, Hui-Shu Hsu, Kuan-Yu Hung
doi : 10.1111/nep.13901
NephrologyVolume 26, Issue 8 p. 669-675
The prevalence of chronic kidney disease (CKD) is on the rise due to population aging and multimorbidity. Taiwan is particularly afflicted by this prevailing ailment. Although multidisciplinary pre-dialysis care has been implemented to halt CKD progression and reduce health-care utilization in Taiwan, more is needed to reduce the local burden of CKD.
Relationship between sodium removal, hydration and outcomes in peritoneal dialysis patients
Natalie M.-Y. Mok, Nicholas Fan, Hazel Finney, Stanley L.-S. Fan
doi : 10.1111/nep.13885
NephrologyVolume 26, Issue 8 p. 676-683
Fluid overload (FO) in peritoneal dialysis (PD) patients is associated with mortality. We explore if low daily sodium removal is an independent risk factor for mortality. We examined severely FO PD patients established for >1?year in expectation that PD prescription would have been optimized for solute clearance and ultrafiltration. We also wish to determine the relationship between kt/v and sodium removal.
A novel urine cell-free DNA preservation solution and its application in kidney transplantation
Qiang Zhou, Feng Liu, Luoying Guo, Ruoyang Chen, Xiaodong Yuan, Chao Li, Liping Shu, Haitao Liu, Yang Zhou, Yu Wu, Haifeng Shi, Hongwen Zhao, Tingya Jiang
doi : 10.1111/nep.13884
NephrologyVolume 26, Issue 8 p. 684-691
Urine cell-free DNA (cfDNA) is a new type of liquid biopsy biomarker used in tumours and allograft injury detection but is highly susceptible to degradation by the high nuclease activity of urine. This study presents a newly developed urine cfDNA preservation solution (AlloU), efficient for examining allograft injury in kidney transplant recipients (KTx).
A new approach to de novo minimal change disease in pregnancy
Sarah Gleeson, Filipa Cardoso, Liz Lightstone, Philip Webster, Kerry Munro, Thomas Cairns
doi : 10.1111/nep.13871
NephrologyVolume 26, Issue 8 p. 692-693
Takayasu's arteritis in a girl with steroid-dependent nephrotic syndrome: Could rituximab be the culprit?
Azusa Sugita, Shun Hashimoto, Riko Sato, Masahi Fujita, Shojiro Watanabe, Tomomi Aizawa, Koji Tsugawa, Hiroshi Tanaka
doi : 10.1111/nep.13870
NephrologyVolume 26, Issue 8 p. 693-694
