Nephrology




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Issue Information

doi : 10.1111/nep.13725

Volume 26, Issue 2, February 2021, Pages: 91-94

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Funnel plots of patient?reported outcomes to evaluate health?care quality: Basic principles, pitfalls and considerations

Esmee M. van der Willik Erik W. van Zwet Tiny Hoekstra Frans J. van Ittersum Marc H. Hemmelder Carmine Zoccali Kitty J. Jager Friedo W. Dekker Yvette Meuleman

doi : 10.1111/nep.13761

Volume 26, Issue 2, February 2021, Pages: 95-104

The statistical review provides insights into the use and interpretation of funnel plots by presenting an overview of the basic principles, pitfalls and considerations when applied to patient?reported outcomes using examples from Dutch routine dialysis care.

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Recommendations by the Asian Pacific society of nephrology (APSN) on the appropriate use of HIF?PH inhibitors

Desmond Y. H. Yap Lawrence P. McMahon Chuan?Ming Hao Nan Hu Hirokazu Okada Yusuke Suzuki Sung Gyun Kim Soo Kun Lim Kriengsak Vareesangthip Chi?Chih Hung Masaomi Nangaku for the APSN HIF?PHI Recommendation Committee

doi : 10.1111/nep.13835

Volume 26, Issue 2, February 2021, Pages: 105-118

The Asian Pacific society of nephrology HIF?PHI Recommendation Committee summarizes the consensus views of the committee regarding the use of HIF?PHI, taking into account both available data and expert opinion in areas where evidence remains scarce.

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Glucocorticoid effects on bone strength in children with renal diseases

Jun Aoyagi Takahiro Kanai Takane Ito Jun Odaka Takashi Saito Hiroyuki Betsui Masanori Kurosaki Tomomi Maru Takanori Yamagata

doi : 10.1111/nep.13832

Volume 26, Issue 2, February 2021, Pages: 119-125

This study examined the effects of glucocorticoids (GCs) on bone strength in children with steroid ?sensitive nephrotic syndrome and IgA nephropathy, and revealed that (a) serum alkaline phosphatase (S?ALP) is a more sensitive bone quality marker than tartrate?resistant acid phosphatase 5b (S?TRACP?5b), (b) bone mineral density loss was observed only when both S?ALP and S?TRACP?5b levels decreased, and (c) undercarboxylated osteocalcin levels do not directly reflect bone strength.

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Diagnostic accuracy of fibroblast growth factor 23 for predicting acute kidney injury in patients with acute decompensated heart failure

Nattha Pramong Pongsathorn Gojaseni Sarunyoo Suttipongkeat Kraiwiporn Kiattisunthorn Anutra Chittinandana

doi : 10.1111/nep.13780

Volume 26, Issue 2, February 2021, Pages: 126-133

In this single centre cohort study, plasma FGF?23 was found to predict AKI in the setting of acute decompensated heart failure. The results could propel further research to explore this biomarker in this high risk AKI setting.

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Rituximab in treatment of collapsing FSGS—A case series

Niveditha Girimaji Joyita Bharati Ritambhra Nada Manish Rathi Harbir Singh Kohli Raja Ramachandran

doi : 10.1111/nep.13757

Volume 26, Issue 2, February 2021, Pages: 134-141

This is a retrospective study reporting the effects of Rituximab on 8 patients with the collapsing form of focal segmental glomerulosclerosis. Whilst retrospective in nature, the study suggested that rituximab might be a promising form of treatment for this condition, which is traditionally resistant to immunosuppression therapy, resulting in a remission rate of 60% with a reasonable safety profile.

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Aetiology, practice patterns and burden of end?stage kidney disease in South Asia and South?East Asia: A questionnaire?based survey

Manisha Sahay Sanjiv Jasuja Sydney Chi Wai Tang Suceena Alexander Vivekanand Jha Tushar Vachharajani Mamun Mostafi Jayakrishnan K. Pisharam Chakko Jacob Atma Gunawan Goh Bak Leong Khin Thida Thwin Rajendra Kumar Agrawal Kriengsak Vareesangthip Roberto Tanchanco Lina Choong Chula Herath Chih?Ching Lin Nguyen The Cuong Ha Phan Haian Syed Fazal Akhtar Ali Alsahow Devinder S. Rana Mohan M. Rajapurkar Vijay Kher Shalini Verma Raja Ramachandran Vinant Bhargava Sonika Puri Gaurav Sagar Anupam Bahl Sandeep Mandal Ashwani Gupta Maurizio Gallieni

doi : 10.1111/nep.13825

Volume 26, Issue 2, February 2021, Pages: 142-152

There are few data on the epidemiology and pattern of practice for end?stage kidney disease from South Asia and South?East Asia. This survey covers 15 Asian countries and provide important information on how ESKD patients are managed in this part of the world.

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Variability and trends over time and across centres in haemodialysis weekly duration in Australia and New Zealand

Isabelle Ethier Yeoungjee Cho Christopher E. Davies Carmel M. Hawley Scott B. Campbell Nicole M. Isbel Elaine M. Pascoe Kevan R. Polkinghorne Matthew Roberts Emily J. See David Semple Carolyn van Eps Andrea K. Viecelli David W. Johnson

doi : 10.1111/nep.13782

Volume 26, Issue 2, February 2021, Pages: 153-163

Patient?level characteristics such as age, sex, BMI, dialysis vintage, ethnicity rather than centre?level ones were associated with weekly duration of haemodialysis, with more variability among home? than in?centre haemodialysis patients in the Australian and New Zealand population.

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Calcium?mediated parathyroid hormone suppression test in uraemic secondary hyperparathyroidism

Ting Xiang Yan Wang Tian Lan Li Zhou

doi : 10.1111/nep.13807

Volume 26, Issue 2, February 2021, Pages: 164-169

In a study on 44 patients with kidney failure on dialysis undergoing parathryoidectomy for hypercalcaemia, the parathyroid hormone?inhibition rate with intravenous calcium gluconate had a negative correlation with parathyroid mass. This interesting non?invasive test needs validation in larger studies.

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Filtering for the best policy: An economic evaluation of policy options for kidney replacement coverage in the Philippines

Diana Beatriz S. Bayani Bernadette Joy Q. Almirol Geovin Dexter C. Uy Mary Joy S. Taneo Romina S. Danguilan Mel?Hatra I. Arakama Arlene B. Lamban Donnah de Leon Glenda Eleanor P. Pamugas Alia Cynthia Luz Yot Teerawatananon

doi : 10.1111/nep.13830

Volume 26, Issue 2, February 2021, Pages: 170-177

This article aims to identify a cost?effective policy strategy for access to kidney replacement therapy in the Philippines, and calls on the government to consider shifting to a Peritoneal Dialysis (PD)?First strategy and support policies that promote kidney transplants among existing PD and haemodialysis patients.

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Levofloxacin based non?rifampicin anti?tuberculous therapy: An effective alternative in renal transplant recipients in resource limited setting

Krishan Lal Gupta Sahil Bagai Harsha Kumar Saurabh Nayak Valliappan Muthu Vivek Kumar Manish Rathi Harbir S Kohli Ashish Sharma Raja Ramachandran

doi : 10.1111/nep.13816

Volume 26, Issue 2, February 2021, Pages: 178-184

In this single?centre study, the authors report their experience using levofloxacin instead of rifampicin for the treatment of tuberculosis after kidney transplantation. Therapy with levofloxacin appeared safe and effective, and may provide a more cost?effective treatment for post?transplant tuberculosis in financially constrained clinical settings.

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Influence of end stage renal disease on CD28 expression and T?cell immunity

Erasmia Sampani Maria Stangou Dimitra?Vasilia Daikidou Vasiliki Nikolaidou Despoina Asouchidou Chrysostomos Dimitriadis George Lioulios Aliki Xochelli Asimina Fylaktou Aikaterini Papagianni

doi : 10.1111/nep.13784

Volume 26, Issue 2, February 2021, Pages: 185-196

End stage renal disease affects specific T?cell subtypes, including CD4+CD28null and CD8+CD28null cells. Although changes in T?cell subpopulations were present before the initiation of dialysis, they were also affected by dialysis modalities, with results favouring continuous ambulatory peritoneal dialysis.

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Advances in understanding the role of adiponectin in renal fibrosis

Dan Zhao Xiaoyu Zhu Lili Jiang Xiu Huang Yangyang Zhang Xuejiao Wei Xiaoxia Zhao Yujun Du

doi : 10.1111/nep.13808

Volume 26, Issue 2, February 2021, Pages: 197-203

This review focuses on the potential renoprotective role of the adipocyte?produced protein, adiponectin, and raises awareness of how increasing adiponectin activity may provide a possible strategy for delaying or abrogating renal fibrosis. The pathways through which adiponectin mediates its anti?fibrotic effects are also detailed.

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Rapidly progressive metastatic adenocarcinoma of unknown primary 2 months following deceased donor renal transplantation—Donor? or recipient?derived?

Lachlan C. McMichael Robert P. Carroll Nitesh N. Rao Patrick Toby Coates

doi : 10.1111/nep.13777

Volume 26, Issue 2, February 2021, Pages: 204

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Absent erythropoietin response to anaemia with mild to moderate chronic kidney disease in pregnancy

Adam Morton

doi : 10.1111/nep.13779

Volume 26, Issue 2, February 2021, Pages: 205

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