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Editor's Choice – John Ingram – July 2023
doi : 10.1093/bjd/ljad176
British Journal of Dermatology, Volume 189, Issue 1, July 2023, Pages i–ii,
Three years on, COVID-19 and the skin: long-term impacts, emerging trends and clinical practice
Esther E Freeman, Ignacio Garcia-Doval, Luigi Naldi, Roderick J Hay
doi : 10.1093/bjd/ljad131
British Journal of Dermatology, Volume 189, Issue 1, July 2023, Pages 1–3
Malignancy risk in atopic dermatitis: heterogenous effects and perspectives
Ida Vittrup
doi : 10.1093/bjd/ljad119
Epidermolysis bullosa: time to come together for better outcomes
Gabriela Petrof, Anna E Martinez
doi : 10.1093/bjd/ljad123
Does the understanding of signalling pathways pave the way to therapies for keratinization disorders?
Hans C Hennies
doi : 10.1093/bjd/ljad139
From genetic characterization to new potential therapeutic options: targeting Bcl-xL in Merkel carcinoma
Thibault Kervarrec
doi : 10.1093/bjd/ljad150
Is the Scale of Alopecia Areata Distress a new method of assessing the psychological burden of alopecia areata?
Taisuke Ito, Reiko Kageyama
doi : 10.1093/bjd/ljad153
Can brepocitinib be formulated into an effective topical therapy to treat mild-to-moderate chronic plaque psoriasis?
William C Cranwell, Rodney D Sinclair
doi : 10.1093/bjd/ljad157
Further evidence for the long-term safety of guselkumab
Antonia Lloyd-Lavery
doi : 10.1093/bjd/ljad161
Relative impact of traditional vs. newer oral antifungals for dermatophyte toenail onychomycosis: a network meta-analysis study
Aditya K Gupta, Maanasa Venkataraman, Mary A Bamimore
doi : 10.1093/bjd/ljad070
Efficacy and safety of baricitinib in combination with topical corticosteroids in paediatric patients with moderate-to-severe atopic dermatitis with an inadequate response to topical corticosteroids: results from a phase III, randomized, double-blind, placebo-controlled study (BREEZE-AD PEDS)
Antonio Torrelo, Barbara Rewerska, Maria Galimberti, Amy Paller, Chin-Yi Yang, Apurva Prakash, Danting Zhu, Marco Antonio G Pontes Filho, Wen-Shuo Wu, Lawrence F Eichenfield
doi : 10.1093/bjd/ljad096
Efficacy and safety of topical brepocitinib cream for mild-to-moderate chronic plaque psoriasis: a phase IIb randomized double-blind vehicle-controlled parallel-group study
Megan N Landis, Stacy R Smith, Gabriel Berstein, Gerald Fetterly, Pranab Ghosh, Gang Feng, Vivek Pradhan, Sudeepta Aggarwal, Christopher Banfield, Elena Peeva, Michael S Vincent, Jean S Beebe, Sanela Tarabar
doi : 10.1093/bjd/ljad098
Safety of guselkumab treatment for up to 5 years in patients with moderate-to-severe psoriasis: pooled analyses across seven clinical trials with more than 8600 patient-years of exposure
Mark G Lebwohl, Joseph F Merola, Katelyn Rowland, Megan Miller, Ya-Wen Yang, Jenny Yu, Yin You, Daphne Chan, Diamant Thaçi, Richard G Langley
doi : 10.1093/bjd/ljad115
Malignancy risk in patients with atopic dermatitis: a population-based cohort study
Joy Wan, Daniel B Shin, Maha N Syed, Katrina Abuabara, Adina R Lemeshow, Zelma C Chiesa Fuxench, Joel M Gelfand
doi : 10.1093/bjd/ljad072
Uptake of tumour necrosis factor-alpha inhibitor biosimilars for psoriasis: a drug utilization study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR)
Duc Binh Phan, Anthony P Bewley, Catherine H Smith, Teena Mackenzie, Christopher E M Griffiths, Mark Lunt, Richard B Warren, Zenas Z N Yiu
doi : 10.1093/bjd/ljad107
Beyond health-related quality of life: initial psychometric validation of a new scale for addressing the gap in assessing the full range of alopecia areata psychosocial burden
Kristina Gorbatenko-Roth, Sarah Wood, Mattea Johnson, Irmina Wallander, Jaime Nugent, Maria Hordinsky
doi : 10.1093/bjd/ljad054
Heterogeneity of reported outcomes in epidermolysis bullosa clinical research: a scoping review as a first step towards outcome harmonization
Eva W H Korte, Tobias Welponer, Jan Kottner, Sjoukje van der Werf, Peter C van den Akker, Barbara Horváth, Dimitra Kiritsi, Martin Laimer, Anna M G Pasmooij, Verena Wally, Maria C Bolling
doi : 10.1093/bjd/ljad077
Chronic activation of Toll-like receptor 2 induces an ichthyotic skin phenotype
Hephzi Tagoe, Sakinah Hassan, Emily Bliss, Gehad Youssef, Wendy Heywood, Kevin Mills, John I Harper, Ryan F L O’Shaughnessy
doi : 10.1093/bjd/ljad095
B-cell lymphoma-extra large is a promising drug target in Merkel cell carcinoma
Kaiji Fan, Nalini Srinivas, Linda Kubat, Jan Gravemeyer, Antje Sucker, Dirk Schadendorf, Thilo Gambichler, Jürgen C Becker
doi : 10.1093/bjd/ljad099
Circulating biomarkers are associated with disease severity of chronic hand eczema and atopic dermatitis
Anna S Quaade, Xing Wang, Julie B K Sølberg, Nina H Ulrich, Benjamin D McCauley, Jacob P Thyssen, Christine Becker, Jeanne D Johansen
doi : 10.1093/bjd/ljad110
Psychosocial impact of pyoderma gangrenosum: a patient perspective
Dasia Crowder, Samantha Herbert, Reneé Haughton
doi : 10.1093/bjd/ljad074
We are not ‘Other’ populations: building research, education and clinical capacity around gender variance in dermatology
Gagandeep Singh, Philip Doiron, Erin Dahlke
doi : 10.1093/bjd/ljad073
Investigator Global Assessment for impetiginization in atopic dermatitis: development and initial reliability testing
Aviël Ragamin, Ron A Tupker, Marlies de Graaf, Thomas Rustemeyer, Suzanne G M A Pasmans, Renske Schappin, Marie L A Schuttelaar
doi : 10.1093/bjd/ljad085
Gain-of-function variants in the KDF1 gene cause hidradenitis suppurativa associated with ectodermal dysplasia by stabilizing IκB kinase α
Alban Ziegler, Frédéric Ebstein, Hanan Shamseldin, Clément Prouteau, Elke Krüger, Yousef M Binamer, Dominique Bonneau, Fowzan S Alkuraya, Ludovic Martin Author Notes
doi : 10.1093/bjd/ljad075
Safety of guselkumab in patients with psoriasis with a history of malignancy: 5-year results from the VOYAGE 1 and VOYAGE 2 trials
Andrew Blauvelt, Diamant Thaçi, Kim A Papp, Vincent Ho, Kamran Ghoreschi, Byung Soo Kim, Megan Miller, Yaung-Kaung Shen, Yin You, Daphne Chan, Jenny Yu, Ya-Wen Yang, Mark G Lebwohl, Alice B Gottlieb, Jeffrey Crowley, Peter Foley
doi : 10.1093/bjd/ljad081
KLK11 ichthyosis: large truncal hyperkeratotic pigmented plaques underscore a distinct autosomal dominant disorder of cornification
Takuya Takeichi, Yasutoshi Ito, John Y W Lee, Chiaki Murase, Yusuke Okuno, Yoshinao Muro, John A McGrath, Masashi Akiyama
doi : 10.1093/bjd/ljad082
Abrocitinib as a novel treatment for lichen sclerosus
Chengbei Bao, Qiuyun Xu, Zhixun Xiao, Haiqing Wang, Renwei Luo, Bo Cheng, Chao Ji, Ting Gong
doi : 10.1093/bjd/ljad129
The Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) score: online assessment and validation study of a specific measure of GPP disease activity
A David Burden, Hervé Bachelez, Siew Eng Choon, Slaheddine Marrakchi, Tsen-Fang Tsai, Hamida Turki, Akimichi Morita, Mark G Lebwohl, Robert Bissonnette, Min Zheng, Milan J Anadkat, Alexander A Navarini, Ming Tang, Christian Thoma, Kristina Callis Duffin
doi : 10.1093/bjd/ljad071
Acute hepatic failure in trimethoprim-induced drug rash with eosinophilia and systemic symptoms (DRESS)
Aveen Connolly, Sarah Walsh, Marianna Philippidou, Jon Salisbury, Daniel Creamer
doi : 10.1093/bjd/ljad087
The geographical variation of melanoma, basal and squamous cell carcinoma in England
Anna Ascott, Birgitta van Bodegraven, Sally Vernon, Cate H Orteu, Zoe C Venables
doi : 10.1093/bjd/ljad100
Head lice: evidence that resistance to physically acting treatments is developing
Ian F Burgess, Elizabeth R Brunton
doi : 10.1093/bjd/ljad106
Photoprotection and skin cancer education: the experiences of renal transplant recipients, a qualitative study – why the ‘personal touch’ is important
Laoise Griffin, Pauline O’Reilly, Marcus Murphy, Gemma Prendergast, Emily Pender, Olga Tummon, Matthew Griffin, Mary Laing
doi : 10.1093/bjd/ljad116
Cutaneous features at injection sites of intravenous mephedrone
Manuel Agud de Dios, Jorge Arroyo-Andres, Carmen Rubio-Muniz, Maria Concepcion Garrido, Eloy Tarin-Vicente
doi : 10.1093/bjd/ljad064
A multistep approach from scoping review to strong evidence: biomarkers in psoriasis
E Sbidian
doi : 10.1093/bjd/ljac101
Which patients with melanoma are a priority for monitoring to detect new primary melanoma?
Aimilios Lallas
doi : 10.1093/bjd/ljad125
OralsO01 Loss of TGFBR2 and activation of PI3 kinase signalling is associated with metastatic cutaneous squamous cell carcinomas
Mairi Treanor-Taylor, Ying Zhang, Daniel Schreyer, Catherine Harwood, Irene Leigh, Peter Bailey, David Wotton, Gareth Inman
doi : 10.1093/bjd/ljad174.001
O02 Neoantigens from actinic keratosis are predicted to be more immunogenic than those from cutaneous squamous cell carcinoma – a strategy for immune escape?
Jason Thomson, Catherine Harwoood, Jessica Strid, Eugene Healy, Jun Wang
doi : 10.1093/bjd/ljad174.002
O03 HPV8 leads to Lrig1+ keratinocyte stem cell expansion into the overlying epidermis
Huw J Morgan, Boris Shorning, Carlotta Olivero, Cinzia Borgogna, Baki Akgul, Marisa Gariglio, Girish K Patel
doi : 10.1093/bjd/ljad174.003
O04 HPV8 E6 leads to Lrig1+ keratinocyte stem cell expansion
Boris Shorning, Huw J Morgan, Carlotta Olivero, Cinzia Borgogna, Marisa Gariglio, Baki Akgul, Girish K Patel
doi : 10.1093/bjd/ljad174.004
O05 Functional roles of lncRNA in cutaneous squamous cell carcinoma disease progression
Max Bone, Catherine Harwood, Irene Leigh, Peter Bailey, Gareth Inman
doi : 10.1093/bjd/ljad174.005
O06 Exploring host–microbiome–immune interactions using singular and multispecies inoculations in optimized 3D skin models
Esmé McPolin-Hall, Abish Stephen, Claire Pardieu, Robert Allaker, Michae Philpott, Ranjit Bhogal, Jenny Pople, Rosalind Hannen
doi : 10.1093/bjd/ljad174.006
O07 Filaggrin insufficiency renders keratinocyte-derived small extracellular vesicles capable of affecting CD1a-mediated T-cell responses and promoting allergic inflammation
Adrian Kobiela, Weronika Hewelt-Belka, Joanna E Frąckowiak, Natalia Kordulewska, Lilit Hovhannisyan, Aleksandra Bogucka, Rachel Etherington, Artur Piróg, Irena Dapic, Susanne Gabrielsson, Sara Brown, Graham S Ogg, Danuta Gutowska-Owsiak
doi : 10.1093/bjd/ljad174.007
O08 Using single-cell transcriptomics to characterize early mechanisms of psoriasis resolution
Luc Francis, Daniel McCluskey, Clarisse Ganier, Xinyi Du-Harpur, David Baudry, Pawan Dhami, Jonathon Barker, Catherine Smith, Francesca Capon, Satveer Mahil
doi : 10.1093/bjd/ljad174.008
O09 Dynamic impact of chronic inflammation on epidermal autophagy pathway
Nazia Uddin, Paola Ostano, Giovanna Chiorino, Jeremy di Domizio, Michel Gilliet, Mike Philpott, Rosalind Hannen, Daniele Bergamaschi
doi : 10.1093/bjd/ljad174.009
O10 STAT3 activation in peripheral blood MAIT cells is a predictive biomarker of response to biologics targeting the IL-23/IL-17 axis
Shane Solanky, Salma Khan, Isabella Tosi, Hannah Dawe, Wan Xinyu, Rosa Andres Ejarque, Hira Bahadur Ale, Katarzyna Grys, Nick Dand, Satveer Mahil, Michael R Barnes, Christopher E M Griffiths, Nick J Reynolds, Catherine H Smith, Richard B Warren, Jonathan Barker, Paola Di Meglio on behalf of the PSORT Consortium
doi : 10.1093/bjd/ljad174.010
O11 The human discs large protein (Dlg1) controls connexin 43 (Cx43) plasma membrane localization and gap junctional communication in keratinocytes
Harry Scott, Li Dong, Sharmila Srinivasan, Andrew Stevenson, Alasdair MacDonald, Paola Massimi, Lawrence Banks, Patricia Martin, Scott Johnstone, Sheila Graham
doi : 10.1093/bjd/ljad174.011
O12 Environmental factors interact with FLG to affect cytokine expression in human primary keratinocytes
Luke Johnston, Mona Etorban, Hannes Becher, Martina Elias, Sara Brown
doi : 10.1093/bjd/ljad174.012
O13 JAK inhibitors to restore skin barrier function in ARCI
Elena Giusto, Florence Enjalbert, Emanuel Rognoni, Matthew Caley, Edel O’Toole
doi : 10.1093/bjd/ljad174.013
O14 Junctional epidermolysis bullosa: repairing the epidermal lipid barrier
Eleri Jones, Supatra Marsh, Ryan O'Shaughnessy, Monique Aumailley, John McGrath, Edel O’Toole, Matthew Caley
doi : 10.1093/bjd/ljad174.014
O15 Using CRISPR-Cas9 to annotate the TYK2 pathway in psoriasis
Sarah Elyoussfi, Shraddha S Rane, Stephen Eyre, Richard B Warren
doi : 10.1093/bjd/ljad174.015
O16 The novel roles of laminin α3 in epidermal barrier function and metabolism
Piotr Parzymies, Eleri Mai Jones, Andrew Mayes, David Messenger, Edel O’Toole, Matthew Caley
doi : 10.1093/bjd/ljad174.016
O17 Endogenous double-stranded RNA (dsRNA) in melanoma: an attack from within
Shaymaa Sadeq, Ruth Plummer, Suwalak Chitcharoen, Penny Lovat, Glyn Nelson, Andreas Werner
doi : 10.1093/bjd/ljad174.017
O18 Molecular crosstalk between PLCγ1 and STAT3 in cutaneous T-cell lymphoma
Victoria Campbell, Charlotte Flanagan, Isabella Tosi, Christine Jones, Sean Whittaker, Susan John, Tracey Mitchell
doi : 10.1093/bjd/ljad174.018
O19 CYLD cutaneous syndrome tumours demonstrate increased NF-κB signalling and diminished collagen organisation.
Joseph Inns, Neil Rajan
doi : 10.1093/bjd/ljad174.019
O20 Advanced melanoma is associated with distinct circulating B-cell profiles enriched with immunoregulatory and autoreactive features
Zena Willsmore, Silvia Crescioli, Lucy Booth, Roman Laddach, Rozalyn Yorke, Robert Harris, Jitesh Chauhan, Alicia Chenoweth, Rebecca Adams, Gabriel Osborn, Ashley Di Meo, Ioannis Prassas, Jenny L C Geh, Akshay J Patel, Gary W Middleton, Alastair D MacKenzie Ross, Ciaran Healey, Eleftherios P Diamandis, Khushboo Sinha, Yin Wu, Sean J Whittaker, Esperanza Perucha, Sophie Papa, Katie E Lacy, Sophia N Karagiannis
doi : 10.1093/bjd/ljad174.020
O21 Single-cell RNA sequencing and proteomic analysis of dermal fibroblasts cultured from female scalp identifies significant alterations in cell populations with age
Richard Baker, Rachael Williams, Gillian Westgate, Alison Pawlus, Jeanna Zguris, Julie Thornton
doi : 10.1093/bjd/ljad174.021
O22 Programmed cell death-1 receptor is a checkpoint in Tbet+ Th17 cells within the tumour microenvironment
Katie Smith, Jing Xuan Lim, Arian Laurence, Shoba Amarnath
doi : 10.1093/bjd/ljad174.022
PostersP01 Tissue slice culture as a patient-derived explant model to investigate immunity and immunotherapy in cutaneous squamous cell carcinoma
George Coltart, Chester Lai, Aymen Al-Shamkhani, Eugene Healy
doi : 10.1093/bjd/ljad174.023
P02 Potential for the loss of endothelial AMBRA1 expression in the tumour microenvironment to identify high-risk patient subsets with nonulcerated AJCC stage I/II melanoma
Roisin Stout, Katie Best, Ioana Cosgarea, Penny Lovat, Jane Armstrong
doi : 10.1093/bjd/ljad174.024
P03 Hydroxypyridone antifungals induce myofibroblast apoptosis in an in vitro model of hypertrophic scars
Alice Lapthorn, Marcus Ilg, Justine Sullivan, Peter Dziewulski, Selim Cellek
doi : 10.1093/bjd/ljad174.025
P04 Skin concentration of 7-dehydrocholesterol is not a limiting factor for vitamin D3 synthesis in older versus younger adults, and a similar response occurs to UVR in these age groups
Oktawia Borecka, John J Dutton, Jonathan C Y Tang, William D Fraser, Lesley E Rhodes
doi : 10.1093/bjd/ljad174.026
P05 Inducible MDM2 ablation increases p53 expression to block papillomatogenesis in HK1.ras transgenic mice
Ana Gutierrez Crispini, Aleksandra Slosarska, David Greenhalgh
doi : 10.1093/bjd/ljad174.027
P06 Functional MDM2 ablation in HK1.ras/fos-Δ5PTEN transgenic mice results in an elevated, p53-mediated block of carcinogenesis that depends upon p53 expression
Sofia Moula, Gavin Turnbull, David Greenhalgh
doi : 10.1093/bjd/ljad174.028
P07 Optimizing DNA specificity and applicability of base and prime editors on COL7A1 variants causing recessive dystrophic epidermolysis bullosa
Imogen Brooks, Maria Rudnytska, Ruta Gebrezgabher, Lukasz Laczmanski, Gregory Newby, David Liu, John McGrath, Joanna Jackow
doi : 10.1093/bjd/ljad174.029
P08 Dissection of the molecular and cellular heterogeneity of dermal fibroblasts in skin fibrosis
Abubkr Ahmed, Thomas Kirk, Laura Forster, Edel O’Toole, Himadri Gupta, Emanuel Rognoni
doi : 10.1093/bjd/ljad174.030
P09 Short-term rho-associated kinase inhibitor treatment promotes primary keratinocyte growth without affecting keratinocyte stem cell properties
Vignesh Jayarajan, George T Hall, Theodoros Xenakis, Neil Bulstrode, Dale Moulding, Sergi Castellano, Wei-Li Di
doi : 10.1093/bjd/ljad174.031
P10 Inducible 14-3-3 sigma/stratifin ablation cooperates with rasHa activation to accelerate papillomatogenesis and induce malignant conversion in transgenic mouse skin carcinogenesis
Rebecca Hardman-Carter, Revvekka Lefkati, Carol McMenemy, David Greenhalgh
doi : 10.1093/bjd/ljad174.032
P12 Tetrapeptide matrikines synchronize circadian rhythms and promote proliferation in human skin cells
Zeyad El-Houni, Alexander Eckersley, Mike Bell, Eleanor Bradley, Victoria Newton, Michael Sherratt, Qing Jun Meng
doi : 10.1093/bjd/ljad174.033
P13 Prediction and in vitro characterization of tetrapeptide matrikines with diverse effects on human dermal fibroblasts
Nathan Jariwala, Matiss Ozols, Alexander Eckersley, Rachel Watson, Bezaleel Mambwe, Andrew Gilmore, Laurent Debelle, Mike Bell, Eleanor Bradley, Yegor Doush, Richard Leroux, Olivier Peschard, Philippe Mondon, Caroline Ringenbach, Laure Bernard, Aurélien Pitois, Michael Sherratt
doi : 10.1093/bjd/ljad174.034
P14 Whole-genome sequencing of malignant cylindroma in CYLD cutaneous syndrome reveals a clinically targetable somatic driver mutation
William Fostier, Ching Chiek Koh, Akhtar Husain, Shirin Namini, Serena Nik-Zainal, Neil Rajan
doi : 10.1093/bjd/ljad174.035
British Journal of Dermatology, Volume 189, Issue 1, July 2023, Page e19
P15 Surface engineering of novel polydimethylsiloxane composites to attract bacteria: potential to treat chronic infected wounds and reduce antimicrobial resistance
Paul Norton, Maria Katsikogianni, David Ansell, Chien-Yi Chang, Julie Thornton
doi : 10.1093/bjd/ljad174.036
P16 How does skin ageing-related basement membrane collagen loss affect the nucleus?
Simranpreet Kaur Summan, Andrew Mayes, David Gunn, Julien Gautrot, Matthew Caley, Edel O’Toole
doi : 10.1093/bjd/ljad174.037
P17 A signature of IL-36 activation in systemic lupus erythematosus skin
Emma J Sumner, Daniel McCluskey, Satveer K Mahil, Myles Lewis, Francesca Capon
doi : 10.1093/bjd/ljad174.038
P18 KLICK syndrome is a hyperproliferative inflammatory skin disorder
Hannah Cherry, Maddy Parsons, Joe Rastrick, Jonathan Hardman-Smart, Paola DiMeglio, John McGrath
doi : 10.1093/bjd/ljad174.039
P19 Inducible 14-3-3 sigma/stratifin ablation accelerates malignant progression in HK1.ras/fos-Δ5PTENflx transgenic mouse skin carcinogenesis
Imogen Rawlinson, Carol McMenemy, David Greenhalgh
doi : 10.1093/bjd/ljad174.040
P20 Engineered peptide for KLK5 inhibition – therapeutic intervention for atopic dermatitis
Jeffrey Mah, Derek Macmillan, Wei-Li Di
doi : 10.1093/bjd/ljad174.041
P21 Tyrosine and serine STAT3 phosphorylation drives cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa as demonstrated using a 3D in vitro model
Virginia Llopis-Hernandez, Katarzyna Balon, Dawei Chen, Jemima Mellerio, John McGrath, Joanna Jacków
doi : 10.1093/bjd/ljad174.042
P22 Fibrosis in delayed wound healing in diabetes: the role of insulin-like growth factor binding proteins
Sharlene Were, Taryn Wilson, Patricia Martin, Catherine Wright
doi : 10.1093/bjd/ljad174.043
P23 Inducible E-cadherin ablation drives malignant progression in HK1.ras.fos.PTENflx/flx carcinogenesis and induces conversion of HK1.fos.PTENflx/flx keratoacanthoma
Rema Zaweia, Abdullah Alyamani, Carol McMenemy, Jean Quinn, David Greenhalgh
doi : 10.1093/bjd/ljad174.044
P24 Emollient use and effects on cutaneous allergen reactions: a preliminary study
Oludolapo Sherifat Katibi, Paul Andrew, Anna Poyner, Abigail Pinnock, Kirsty Brown, Rob Byers, Michael Cork, Simon Danby
doi : 10.1093/bjd/ljad174.045
P25 Hsa-miR-6727-5p contributes to the impact of high-density lipoprotein on fibroblast wound healing in vitro
Khaled Bastaki, Jamie Tarlton, Richard Lightbody, Patricia Martin, Annette Graham
doi : 10.1093/bjd/ljad174.046
P26 Characterization of skin barrier defects in atopic dermatitis patients using attenuated total reflection Fourier transform infrared spectroscopy
Samuel Williams, Simon Danby
doi : 10.1093/bjd/ljad174.047
P27 Uncovering the roles of lysosomal protease cathepsin H in atopic dermatitis
Theresa Tachie-Menson, Atqiya Azizah, Aaron Hughes, Ryan O'Shaughnessy
doi : 10.1093/bjd/ljad174.048
P28 Understanding ethnic inequality and barriers to participation in artificial intelligence (AI) image analysis research in dermatology
Alexandra Paolino, Wei Ren Tan, Shern-Ping Choy, Byung Jin Kim, Sarah Man Lin Lim, Jiwon Seo, Sze Ping Tan, Michael Duckworth, Bolaji Coker, Koyinsola Quadry, Gary Mulcahy, Jonathan N W N Barker, Magnus Lynch, Mark Stephen Corbett, Catherine H Smith, Satveer K Mahil
doi : 10.1093/bjd/ljad174.049
P29 Manuka honey downregulates IL-4-induced CCL26 via activation of the aryl hydrocarbon receptor
Abdullah A Alangari, Matin Dokht Ashoori, Wisam Alwan, Brigitta Stockinger, Jonathan N Barker, Emma Wincent, Paola Di Meglio
doi : 10.1093/bjd/ljad174.050
P30 Microsatellite instability in cutaneous squamous cell carcinoma
Georgie Holt, Christine Hayes, Rachel Phelps, Akhtar Husain, Christopher Lamb, Richard Gallon, Neil Rajan
doi : 10.1093/bjd/ljad174.051
P31 Dissecting the epigenetic and transcriptional regulators in keloid scars
Stavroula Tekkela, Elena M Drudi, Tanya Shaw, Mike Philpott, Edel O’Toole, Emanuel Rognoni
doi : 10.1093/bjd/ljad174.052
P32 Restoring the ageing skin barrier in vitro
Priya Garcha, Eleri Jones, Jennifer Shelley, Matthew Caley
doi : 10.1093/bjd/ljad174.053
P33 Investigating the utility and exploring biological targets of micro-wound healing compounds in 2D and 3D skin models
Metka Gorkic, David Messenger, Linda Wainwright, John Connelly, Cleo L Bishop
doi : 10.1093/bjd/ljad174.054
Safety of treatment with guselkumab in clinical trials for up to 5 years in patients with moderate-to-severe plaque psoriasis
doi : 10.1093/bjd/ljad170
Creating the Scale of Alopecia Areata Distress to measure a wide range of negative emotional, social and relationship disease consequences in adults
doi : 10.1093/bjd/ljad175
Better understand about circulating biomarkers and disease severity of chronic hand eczema and atopic dermatitis
doi : 10.1093/bjd/ljad173
