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Treating a chronic disease without chronic adherence
Varun Ranpariya,Esther A. Balogh &Steven R. Feldman
doi : 10.1080/09546634.2020.1869038
Page 131 | Accepted author version posted online: 23 Dec 2020, Published online:01 Feb 2021
Defining the role of mirtazapine in the treatment of refractory pruritus
Bilal Fawaz,Bahir H. Chamseddin &John R. Griffin
doi : 10.1080/09546634.2019.1630702
Pages 132-136 | Received 12 Mar 2019, Accepted 27 May 2019, Accepted author version posted online: 10 Jun 2019, Published online: 27 Jun 2019
Mirtazapine has traditionally been used for the treatment of major depressive disorder, with an added benefit in patients who have comorbid insomnia or anxiety. Recent studies describe its usefulness in treating refractory pruritus of various causes as well. Our goal is to better define the use of mirtazapine in the treatment of refractory pruritus.
Difference in vasoconstrictors: oxymetazoline vs. brimonidine
Nwanneka Okwundu,Abigail Cline &Steven R. Feldman
doi : 10.1080/09546634.2019.1639606
Pages 137-143 | Received 09 May 2019, Accepted 16 Jun 2019, Accepted author version posted online: 11 Jul 2019, Published online: 12 Aug 2019
Topical oxymetazoline and brimonidine are the only medications approved for treating persistent facial erythema of rosacea. This review aims to investigate the efficacy, safety, pharmacodynamics, and pharmacokinetic properties of oxymetazoline and brimonidine.
Approach to treatment of refractory dissecting cellulitis of the scalp: a systematic review
Jamael Thomas &Crystal Aguh
doi : 10.1080/09546634.2019.1642441
Pages 144-149 | Received 26 Apr 2019, Accepted 18 Jun 2019, Accepted author version posted online: 26 Jul 2019, Published online: 09 Aug 2019
Dissecting cellulitis is a chronic inflammatory dermatosis that results in disfiguring and painful, purulent lesions. Treatment of patients with disease resistant to standard therapies, including intralesional or topical steroids or antibiotics, can be a dilemma for clinicians.
Sea urchin injuries: a review and clinical approach algorithm
Ziv Schwartz,Marc Cohen &Shari R. Lipner
doi : 10.1080/09546634.2019.1638884
Pages 150-156 | Received 11 Jun 2019, Accepted 28 Jun 2019, Accepted author version posted online: 01 Jul 2019, Published online: 11 Jul 2019
Sea urchin injuries (SUIs) are among the most common marine injuries; however, there are no guidelines to dictate appropriate workup and treatment. Complications vary significantly depending on the extent of injury, site of injury and elapsed time to medical attention. Timely and appropriate management can prevent long-term morbidity despite the deceptively innocuous appearance of these injuries. We review the English literature on SUIs and offer an algorithm to aid in the management of affected patients. We found that superficially retained spines may trigger a local granulomatous inflammatory response, while spines retained near deep structures may induce sea urchin arthritis, inflammatory tenosynovitis, among other delayed complications. Therefore, we recommend immediate inactivation of pro-inflammatory compounds by hot water soaks at the time of injury, followed by extraction of all spines by a physician. Imaging is a valuable component of risk stratification to determine depth and location of spines, which guides selection of appropriate extraction technique to prevent long-term morbidity.
Mohs surgery for the treatment of lentigo maligna and lentigo maligna melanoma – a systematic review
Ajay N. SharmaORCID Icon,Delila P. Foulad,Linda Doan,Patrick K. Lee &Natasha Atanaskova MesinkovskaORCID Icon
doi : 10.1080/09546634.2019.1690624
Pages 157-163 | Received 23 Oct 2019, Accepted 01 Nov 2019, Accepted author version posted online: 07 Nov 2019, Published online: 20 Nov 2019
The role of Mohs micrographic surgery (MMS) in the treatment of lentigo maligna (LM), and lentigo maligna melanoma (LMM) has been controversial. The use of frozen sections is commonly cited as a suboptimal way to distinguish atypical melanocytes, resulting in traditional wide-local excision techniques as the mainstay of therapy.
Disease burden and treatment history among adults with atopic dermatitis receiving systemic therapy: baseline characteristics of participants on the EUROSTAD prospective observational study
Marjolein de Bruin-Weller,Andrew E. Pink,Annalisa Patrizi,Ana M. Gimenez-Arnau,Tove Agner,Pierre-Paul Roquet-Gravy,Silvia M. Ferrucci,Petr Arenberger,Ake Svensson,Marie L.A Schuttelaar,Audrey Nosbaum,Shyamalie Jayawardena,Elena Rizova,Marius Ardeleanu,Laurent Eckert &Zafer E. Ozturk
doi : 10.1080/09546634.2020.1866741
Pages 164-173 | Received 24 Nov 2020, Accepted 16 Dec 2020, Published online: 18 Jan 2021
Insights into the real-world treatment paradigm and long-term burden of atopic dermatitis (AD) are needed to inform clinical and health policy decisions.
Dose–response association between vitamin D deficiency and atopic dermatitis in children, and effect modification by gender: a case-control study
Amal Ahmed Mohamed,Eman Mohamed Salah Ahmed,Youssef M. K. Farag,Nermeen Ibrahim Bedair,Nourelhuda Ahmed Nassar &Ayat Ibrahim Mohamed Ghanem
doi : 10.1080/09546634.2019.1643447
Pages 174-179 | Received 07 Jun 2019, Accepted 08 Jul 2019, Accepted author version posted online: 12 Jul 2019, Published online: 02 Aug 2019
Vitamin D is a regulatory factor for immunity and skin barrier functions. It is hypothesized to be linked to atopic dermatitis (AD) which is characterized by interaction between epidermal barrier dysfunction and dysregulation of skin immune functions.
Association between infliximab concentrations and clinical response in psoriasis: a prospective cohort study
M. Colls-Gonzalez,J. Notario-Rosa,J. Bas-Minguet,A. Padullés-Zamora,F. Morandeira-RegoORCID Icon,F. Valent?-Medina,H. Colom-Codina &N. Padullés-Zamora
doi : 10.1080/09546634.2019.1690623
Pages 180-187 | Received 24 Oct 2019, Accepted 01 Nov 2019, Accepted author version posted online: 07 Nov 2019, Published online: 20 Nov 2019
Infliximab (IFX) trough concentrations (Cmin) have been linked to treatment efficacy in psoriatic patients. Inter-individual IFX Cmin variability and factors influencing IFX pharmacokinetics could explain differences in treatment response.
Antibiotics for acne vulgaris: using instagram to seek insight into the patient perspective
Pooja S. Reddy,Logan C. DeBord,Rohit Gupta,Paarth Kapadia,Alina Mohanty &Harry Dao Jr
doi : 10.1080/09546634.2019.1631432
Pages 188-192 | Received 01 Feb 2019, Accepted 31 May 2019, Accepted author version posted online: 13 Jun 2019, Published online: 27 Jun 2019
Monitoring of public social media posts is an underutilized method to understand patients’ perspectives regarding their condition and treatment. We investigated information shared by Instagram users of oral and topical antibiotics for treatment of acne vulgaris.
Crystallized phenol for sacral hidradenitis suppurativa
Ersin Turan,Osman Dogru,Süleyman Kargin,Ramazan Saygin Kerimoglu &Emet Ebru Nazik
doi : 10.1080/09546634.2019.1638878
Pages 193-196 | Received 27 Oct 2018, Accepted 23 May 2019, Accepted author version posted online: 01 Jul 2019, Published online: 14 Aug 2019
Multiple treatment options for hidradenitis suppurativa (HS) have been suggested; none 100% successful. We assessed crystallized phenol treatment (CPT) for sacral HS.
Effect of Cedar (Ziziphus spina-christi) topical solution in mild to moderate acne vulgaris: a randomized clinical study
Rasoul Shakiba,Mohammad Ali Nilforoushzadeh,Fataneh Hashem-Dabaghian,Bagher Minaii Zangii,Ali Ghobadi,Laila Shirbeigi,Jale Aliasl,Mahdad Shakiba &Roshanak Ghods
doi : 10.1080/09546634.2019.1692125
Pages 197-202 | Received 23 Sep 2019, Accepted 26 Oct 2019, Published online: 24 Nov 2019
Acne is the most prevalent skin disease in the world and antibiotics as its standard treatments have limited and also adverse effects. Cedar (Ziziphus spina-christi) has medicinal properties like antibacterial activity and is used topically for treatment of some kinds of skin problems in Persian medicine. The aim of this study was to evaluation the efficacy of topical cedar solution of acne vulgaris.
Real-world treatment patterns and healthcare costs of biologics and apremilast among patients with moderate-to-severe plaque psoriasis by metabolic condition status
Steven R. Feldman,Jingchuan Zhang,Diane J. Martinez,Lorena Lopez-Gonzalez,Elizabeth Hoit Marchlewicz,George Shrady,Alan M. Mendelsohn &Yang Zhao
doi : 10.1080/09546634.2019.1698699
Pages 203-211 | Received 11 Nov 2019, Accepted 18 Nov 2019, Accepted author version posted online: 26 Nov 2019, Published online: 08 Dec 2019
To compare treatment patterns and costs among psoriasis patients with and without metabolic conditions newly initiating a biologic or apremilast.
Patients’ knowledge about psoriasis and comorbidities; their participation in treatment decisions
Ka?an Cing?z,Kamer Gündüz &I??l ?nan?r
doi : 10.1080/09546634.2019.1638880
Pages 212-214 | Received 09 May 2019, Accepted 16 Jun 2019, Accepted author version posted online: 01 Jul 2019, Published online: 11 Jul 2019
Psoriasis is a common chronic inflammatory disease. Having more information about psoriasis and comorbid diseases means that patients have more involvement in treatment.
Evaluating and reducing xerosis in competitive swimmers: an in vitro study and randomized controlled clinical trial
Kimball Sheehan,Darrah Sheehan &Mary Margaret Noland
doi : 10.1080/09546634.2019.1638882
Pages 215-219 | Received 03 Jun 2019, Accepted 27 Jun 2019, Accepted author version posted online: 01 Jul 2019, Published online: 11 Jul 2019
Xerosis is a common problem with significant sequelae in competitive swimmers, and it results from transepidermal water loss. This study evaluates moisture barriers for reducing xerosis in competitive swimmers.
Immunomodulatory effects of topical diphencyprone for the treatment of acute urban cutaneous leishmaniasis
Yalda Nahidi,Vahid Mashayekhi Goyonlo,Pouran Layegh,Faezeh Taghavi &Mona Najaf Najafi
doi : 10.1080/09546634.2019.1642997
Pages 220-226 | Received 02 Jul 2019, Accepted 08 Jul 2019, Accepted author version posted online: 11 Jul 2019, Published online: 01 Aug 2019
Efficacious and safe treatments are lacking for cutaneous leishmaniasis (CL). This study investigates the efficacy of adding diphencyprone immunotherapy to conventional meglumine antimoniate (MA) treatment for acute urban CL.
Experiences of barbed polydioxanone (PDO) cog thread for facial rejuvenation and our technique to prevent thread migration
Mehmet Unal,Gizem Kaya ?slamo?lu,Gülbahar ?rün Unal &Nihal K?ylü
doi : 10.1080/09546634.2019.1640347
Pages 227-230 | Received 26 Apr 2019, Accepted 16 Jun 2019, Accepted author version posted online: 03 Jul 2019, Published online: 15 Jul 2019
One of the most common nonsurgical options for facial rejuvenation is lifting using threads. Application of polydioxanone (PDO) threads is generally secure and effective procedure, but complications on the involved regions can occur.
Circular RNA ITCH downregulates GLUT1 and suppresses glucose uptake in melanoma to inhibit cancer cell proliferation
Qianli Lin,Hua Jiang &Defeng Lin
doi : 10.1080/09546634.2019.1654069
Pages 231-235 | Received 03 Jun 2019, Accepted 02 Aug 2019, Accepted author version posted online: 12 Aug 2019, Published online: 08 Sep 2019
Circular RNA ITCH has been proved as a tumor suppressor in several types of cancer. Genetic alterations are known to play important roles in melanoma development. However, the function of circular RNAs and the role of ITCH in melanoma are still hardly known.
Efficacy and safety of a new 10% topical minoxidil versus 5% topical minoxidil and placebo in the treatment of male androgenetic alopecia: a trichoscopic evaluation
Soheir Ghonemy,Abeer Alarawi &Hagar Bessar
doi : 10.1080/09546634.2019.1654070
Pages 236-241 | Received 11 Jun 2019, Accepted 02 Aug 2019, Accepted author version posted online: 12 Aug 2019, Published online: 21 Oct 2019
Androgenetic alopecia is a stressful condition for males. Minoxidil 2% and 5% have been FDA approved for treatment of this condition. In literature, all studies have compared minoxidil 5% with 2%. Although other concentrations (2% to 12.5%) are available nowadays, we believe our study is the first to compare 10% versus 5% topical minoxidil in treatment of AGA.
Efficacy of stem cell-conditioned medium vs. platelet-rich plasma as an adjuvant to ablative fractional CO2 laser resurfacing for atrophic post-acne scars: a split-face clinical trial
Ensaf M. Abdel-Maguid,Sara M. Awad,Youssef S. Hassan,Mohamed A. El-Mokhtar,Heba EM EL-Deek &Marwa MA Mekkawy
doi : 10.1080/09546634.2019.1630701
Pages 242-249 | Received 22 Apr 2019, Accepted 26 May 2019, Accepted author version posted online: 10 Jun 2019, Published online: 05 Jul 2019
To explore the impact of using topical stem cell-conditioned medium (SC-CM) after fractional carbon dioxide laser (FCL) vs. combined FCL and platelet-rich plasma (PRP) or FCL alone in treatment of atrophic acne scars.
Impact of cyclosporin treatment on health-related quality of life of patients with alopecia areata
Vivien Wai Yun Lai,Gang Chen &Rodney Sinclair
doi : 10.1080/09546634.2019.1654068
Pages 250-257 | Received 20 May 2019, Accepted 03 Aug 2019, Accepted author version posted online: 07 Aug 2019, Published online: 20 Aug 2019
Alopecia areata (AA) is a disfiguring disease with substantial psychological burden. No studies explore the efficacy of pharmacotherapy through health-related quality of life (HRQoL) using both disease-specific and generic quality of life (QoL) instruments. We present the first study to elicit health utility from patients with AA and to evaluate the efficacy of cyclosporin in relation to HRQoL using both measures.
Comparing the efficacy of pulsed dye laser, Q-Switched Nd-YAG, CO2, and combined CO2 and Q-Switched Nd-YAG lasers for the treatment of cutaneous macular amyloidosis
Mohammad Radmanesh,Forough Ghanatir &Ramin Radmanesh
doi : 10.1080/09546634.2019.1654071
Pages 258-260 | Received 05 Jul 2019, Accepted 03 Aug 2019, Accepted author version posted online: 15 Aug 2019, Published online: 25 Aug 2019
No topical and systemic treatment is proven to be effective on Cutaneous Macular Amyloidosis (CMA). The physical removal of the deposited protein by lasers may be a better choice.
Guselkumab in the treatment of concomitant hidradenitis suppurativa, psoriasis, and Crohn’s disease
Hannah S. BermanORCID Icon,Natalie M. Villa,Vivian Y. Shi &Jennifer L. Hsiao
doi : 10.1080/09546634.2019.1654067
Pages 261-263 | Received 15 Jul 2019, Accepted 02 Aug 2019, Accepted author version posted online: 07 Aug 2019, Published online: 25 Aug 2019
Hidradenitis suppurativa (HS) is a debilitating skin condition whose pathogenesis is poorly understood, although interleukin (IL)-23 may play a role. IL-23 is also implicated in the pathogenesis of Crohn’s disease (CD) and psoriasis, both of which can occur in patients with HS.
Treatment of Majocchi granuloma. A retrospective study of 36 cases
Alexandro Bonifaz,Andrés Tirado-S?nchez,Patricia Mercadillo &Leonel Fierro-Arias
doi : 10.1080/09546634.2019.1646392
Pages 264-265 | Received 29 Jun 2019, Accepted 16 Jul 2019, Accepted author version posted online: 26 Jul 2019, Published online: 12 Aug 2019
Cannabinoids for the treatment of chronic refractory pruritus
Raveena Khanna,Rayva Khanna,George Denny &Shawn G. Kwatra
doi : 10.1080/09546634.2019.1639603
Pages 266-267 | Received 03 Jun 2019, Accepted 28 Jun 2019, Accepted author version posted online: 02 Jul 2019, Published online: 15 Jul 2019
Acne scars: classification and treatment
Jesus Alberto Cardenas-de la Garza&Sarah L. Taylor
doi : 10.1080/09546634.2019.1638879
Page 268 | Received 06 Jun 2019, Accepted 17 Jun 2019, Accepted author version posted online: 01 Jul 2019, Published online: 11 Jul 2019
