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Polygenic Risk Scores and Genetics in Psychiatry
Ned H. Kalin, M.D.
doi : 10.1176/appi.ajp.20220789
Volume 179, Issue 11
From Soldier’s Heart to Shared Genetic Risk: PTSD and Cardiovascular Disease
Robert J. Ursano, M.D., and Murray B. Stein, M.D., M.P.H.
Harnessing the Power of Population Cohorts to Study the Relationship Between Endocrine-Metabolic Disorders and Depression
Anders Jespersen, Ph.D., Zeynep Yilmaz, Ph.D., Bjarni J. Vilhjálmsson, Ph.D.
A Revolution Is Brewing in How We Understand the Shared Genetic Causes of Psychiatric Disorders
Angelica Ronald, Ph.D., and Oliver Pain, Ph.D.
Proof-of-Principle Study on ECT Illustrates Challenges and Possible Merits of Using Polygenic Risk Scores to Predict Treatment Response in Psychiatry
Bart P.F. Rutten, M.D., Ph.D., and Suzanne C. van Bronswijk, M.D., Ph.D.
Early-Onset Psychosis and Autism Spectrum Disorder: Similar Rates of Deleterious Copy Number Variants, Yet Diverse Phenotypic Manifestations
David H. Skuse, M.D., F.R.C.Psych.
Polygenic Scores in Psychiatry: On the Road From Discovery to Implementation
Cathryn M. Lewis, Ph.D., Evangelos Vassos, M.D., Ph.D.
Defining Recovery From Alcohol Use Disorder: Development of an NIAAA Research Definition
Brett T. Hagman, Ph.D., Daniel Falk, Ph.D., Raye Litten, Ph.D., George F. Koob, Ph.D.
Leveraging Large-Scale Genetics of PTSD and Cardiovascular Disease to Demonstrate Robust Shared Risk and Improve Risk Prediction Accuracy
Antonia V. Seligowski, Ph.D., Burook Misganaw, Ph.D., Lucie A. Duffy, B.A., Kerry J. Ressler, M.D., Ph.D., Guia Guffanti, Ph.D.
Genetic and Environmental Contribution to the Co-Occurrence of Endocrine-Metabolic Disorders and Depression: A Nationwide Swedish Study of Siblings
Marica Leone, Ph.D., Ralf Kuja-Halkola, Ph.D., Amy Leval, Ph.D., Agnieszka Butwicka, M.D., Ph.D., Jakob Skov, M.D., Ph.D., Ruyue Zhang, Ph.D., Shengxin Liu, M.Sc., Henrik Larsson, Ph.D., Sarah E. Bergen, Ph.D.
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation
Guy Hindley, M.D., Oleksandr Frei, Ph.D., Alexey A. Shadrin, Ph.D., Weiqiu Cheng, Ph.D., Kevin S. O’Connell, Ph.D., Romain Icick, M.D., Nadine Parker, Ph.D., Shahram Bahrami, Ph.D., Naz Karadag, M.Sc., Daniel Roelfs, M.Sc., Børge Holen, M.D., Aihua Lin, Ph.D., Chun C. Fan, M.D., Srdjan Djurovic, Ph.D., Anders M. Dale, Ph.D., Olav B. Smeland, M.D., Ole A. Andreassen, M.D.
Association Between Polygenic Risk Scores and Outcome of ECT
Robert Sigström, M.D., Ph.D., Kaarina Kowalec, Ph.D., Lina Jonsson, Ph.D., Caitlin C. Clements, Ph.D., Robert Karlsson, Ph.D., Axel Nordenskjöld, M.D., Ph.D., Erik Pålsson, Ph.D., Patrick F. Sullivan, M.D., Mikael Landén, M.D., Ph.D.
Similar Rates of Deleterious Copy Number Variants in Early-Onset Psychosis and Autism Spectrum Disorder
Catherine A. Brownstein, Ph.D., Elise Douard, M.Sc., Josephine Mollon, Ph.D., Richard Smith, Ph.D., Margaret A. Hojlo, B.A., Ananth Das, B.A., Maria Goldman, B.A., Emily Garvey, B.A., Kristin Cabral, B.S., Jianqiao Li, B.S., Joshua Bowen, B.S., Abhijit S. Rao, B.S.A., Casie Genetti, M.S., C.G.C., Devon Carroll, A.P.R.N.-B.C., Emma E. M. Knowles, Ph.D., Emma Deaso, B.A., Pankaj B. Agrawal, M.D., Alan H. Beggs, Ph.D., Eugene D’Angelo, Ph.D., Laura Almasy, Ph.D., Aaron Alexander-Bloch, M.D., Ph.D., Zohra Saci, Ph.D., Clara A. Moreau, Ph.D., Guillaume Huguet, Ph.D., Anthony J. Deo, M.D., Ph.D., Sébastien Jacquemont, M.D., David C. Glahn, Ph.D., Joseph Gonzalez-Heydrich, M.D.
Cannabis and Cannabinoids in Psychiatry: Risks and Benefits
H. Yavuz Ince, M.D.
Distinguishing the Effects of Lead-Time Bias and Duration of Untreated Psychosis
Katherine G. Jonas, Ph.D., Laura J. Fochtmann, M.D., Greg Perlman, Ph.D., John M. Kane, M.D., Evelyn J. Bromet, Ph.D., Roman Kotov, Ph.D.
Distinguishing the Effects of Lead-Time Bias and Duration of Untreated Psychosis: Reply to Jonas et al.
Donal O’Keeffe, Ph.D., Anthony Kinsella, M.Sc., John L. Waddington, Ph.D., D.Sc., Mary Clarke, M.D.
