Behavioural Brain Research




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doi : 10.1016/S0166-4328(23)00233-4

Volume 449, 9 July 2023, 114515

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Stratifying ASD and characterizing the functional connectivity of subtypes in resting-state fMRI

Pengchen Ren a,b,c,1, Qingshang Bi a,c,1, Wenbin Pang a, Meijuan Wang c, Qionglin Zhou a, Xiaoshan Ye a, Ling Li a,*, Le Xiao

doi : 10.1016/j.bbr.2023.114458

Volume 449, 9 July 2023, 114458

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Repeated donkey milk consumption reduces anxiety-like behaviors and brain oxidative damage to lipids in mice

Emmanuella de Oliveira Moura Ara?jo a, Elaine Cristina Gavioli b, Victor Anast´acio Duarte Holanda b, Val´eria Costa da Silva b, Tayanna Bernardo Oliveira Nunes Messias a, Larissa Maria Gomes Dutra a,*, Matheus Cardoso de Oliveira b, Rita de C´assia Ramos do Egypto Queiroga a,1, Gerlane Coelho Bernardo Guerra b, Juliana Kessia Barbosa Soares

doi : 10.1016/j.bbr.2023.114477

Volume 449, 9 July 2023, 114477

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Effects of combined use of alcohol and delta-9-tetrahydrocannibinol on working memory in Long Evans rats

Lauren K. Carrica a, Chan Young Choi a, Francis A. Walter b, Brynn L. Noonan a, Linyuan Shi a, Clare T. Johnson d, Heather B. Bradshaw d, Nu-Chu Liang a,b, Joshua M. Gulley

doi : 10.1016/j.bbr.2023.114475

Volume 449, 9 July 2023, 114475

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Potential Biomarkers of impulsivity in mild traumatic brain injury: A pilot study

Ma?ra Gl´oria de Freitas Cardoso a,b, Jo?ao Lu?s Vieira Monteiro de Barros a, Rafael Alves Bonfim de Queiroz c, Natalia Pessoa Rocha d, Carlisa Silver a, Agnes St´ephanie da Silva a,b, Ewelin Wasner Machado da Silva a, Isadora Gonc?alves Roque a, Ju? lia de Lima Carvalho a, Laura Ferreira dos Santos a, Leti? cia Bitencourt Cota a, Lucas Miranda Lemos a, Mariana Figueiredo Miranda a, Millena Figueiredo Miranda a, Pedro Parenti Vianna a, Rafael Arantes Oliveira a, Tiago de Oliveira Furlam a, Tu? lio Safar Sarquis Soares a, Vinicius Sousa Pietra Pedroso a, Rodrigo Moreira Faleiro e, ´Erica Leandro Marciano Vieira a,f, Antˆonio L?cio Teixeira g,h, Leonardo Cruz de Souza a,b,i,*,1, Aline Silva de Miranda a,b,j,*,1, Mlnas Gerais’ Traumatic Brain Injury Study Group

doi : 10.1016/j.bbr.2023.114457

Volume 449, 9 July 2023, 114457

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Ramelteon improves blood-brain barrier of focal cerebral ischemia rats to prevent post-stroke depression via upregulating occludin

Xuchen Qi a,1, Ziqi Tang b,1, Xian Shao c,1, Zhaowei Wang d, Mengyun Li c, Xiaobing Zhang e, Lingyan He f,*,2, Jianli Wang e,*,2, Xuebin Yu

doi : 10.1016/j.bbr.2023.114472

Volume 449, 9 July 2023, 114472

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Rat BM-MSCs secretome alone and in combination with stiripentol and ISRIB, ameliorated microglial activation and apoptosis in experimental stroke

Neha Dhir a, Ashish Jain a, Amit Raj Sharma b, Sunil Sharma a, Dhruv Mahendru a, Ajay Patial c, Deepti Malik a,d, Ajay Prakash a, Savita Verma Attri c, Shalmoli Bhattacharyya e, Bishan Das Radotra f, Bikash Medhi

doi : 10.1016/j.bbr.2023.114471

Volume 449, 9 July 2023, 114471

Stroke, a devastating neurological emergency, is the leading cause of worldwide mortality and functional disability. Combining novel neuroprotective drugs offers a way to improve the stroke intervention outcomes.

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The differential influence of PZM21, a nonrewarding μ-opioid receptor agonist with G protein bias, on behavioural despair and fear response in mice

Lucja Szumiec a,*, Ryszard Bugno b, Lukasz Szumiec a, Ryszard Przewlocki

doi : 10.1016/j.bbr.2023.114466

Volume 449, 9 July 2023, 114466

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Xanthine-induced deficits in hippocampal behavior and abnormal expression of hemoglobin genes

Jun Kambe a, Shiho Miyata a, Chunmei Li b, Yuki Yamamoto a, Kentaro Nagaoka

doi : 10.1016/j.bbr.2023.114476

Volume 449, 9 July 2023, 114476

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Deep brain stimulation of the dorsal raphe induces anxiolytic and panicolytic-like effects and alters serotonin immunoreactivity

J.A. Lemes a,1, M.S.C.F. Silva a,1, B.S.M. Gonçalves a, I.C. C´espedes b, M.B. Viana a,

doi : 10.1016/j.bbr.2023.114462

Volume 449, 9 July 2023, 114462

Previously we showed that Deep Brain Stimulation (DBS) of the dorsal region (DRD) and of the lateral wings of the dorsal raphe (lwDR) respectively decreases anxiety and panic-like responses in the elevated T-maze (ETM).

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Multiple decrements in switch task performance in female rats exposed to space radiation

Samuel Stephenson a, Aiyi Liu b, Ashley A. Blackwell b,c, Richard A. Britten

doi : 10.1016/j.bbr.2023.114465

Volume 449, 9 July 2023, 114465

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MG53 ameliorates nerve injury induced neuropathic pain through the regulation of Nrf2/HO-1 signaling in rats

Xuan-Zhi Zhu, Jing-Qiong Wang, Yao-Hua Wu

doi : 10.1016/j.bbr.2023.114489

Volume 449, 9 July 2023, 114489

Neuropathic pain is one of the most common types of chronic pain, and it arises as a direct consequence of a lesion or disease that affects the somatosensory system. Mitsugumin53 (MG53), which is a member of the TRIM family of proteins and is known as TRIM72, exerts protective effects on muscle, lung, kidney, brain, and other cells or tissues.

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The role of the oxytocinergic system in the antidepressant-like effect of swimming training in male mice

Amir Emad Azari, Maghsoud Peeri *, Forouzan Fattahi Masrour

doi : 10.1016/j.bbr.2023.114474

Volume 449, 9 July 2023, 114474

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5-HT1B receptors in the basolateral amygdaloid nucleus regulate anxiety-like behaviors through AC-PKA signal pathway in a rat model of Parkinson’s disease

Guoyi Tang a, Yuan Guo a, Li Zhang a, Tao Wang a, Ruotong Li a, Jie Yang a, Yixuan Wang b, Jian Liu

doi : 10.1016/j.bbr.2023.114488

Volume 449, 9 July 2023, 114488

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Ketamine supresses REM sleep and markedly increases EEG gamma oscillations in the Wistar Kyoto rat model of treatment-resistant depression

Sandor Kantor a,b,*, Michael Lanigan a,c, Lauren Giggins a, Lisa Lione c, Lilia Magomedova b, In´es de Lannoy b, Neil Upton a, Mark Duxon

doi : 10.1016/j.bbr.2023.114473

Volume 449, 9 July 2023, 114473

Wistar–Kyoto (WKY) rats exhibit depression-like characteristics and decreased sensitivity to monoamine-based antidepressants, making them a suitable model of treatment-resistant depression (TRD).

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Striatal adenosine A2A receptor involvement in normal and large nest building deer mice: Perspectives on compulsivity and anxiety

D. Saaiman a, L. Brand a, G. de Brouwer a, H. Janse van Rensburg b, G. Terre’Blanche b, L. Legoabe b, T. Krahe c, D. Wolmarans

doi : 10.1016/j.bbr.2023.114492

Volume 449, 9 July 2023, 114492

Obsessive-compulsive disorder (OCD) is characterized by recurring obsessive thoughts and repetitive behaviors that are often associated with anxiety and perturbations in cortico-striatal signaling.

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Inhibition of TREM-1 ameliorates Lipopolysaccharide-induced depressive-like behaviors by alleviating neuroinflammation in the PFC via PI3K/Akt signaling pathway

Anhui Fu a, Fei Qiao a, Hao Feng a, Qing Luo

doi : 10.1016/j.bbr.2023.114464

Volume 449, 9 July 2023, 114464

Neuroinflammation is closely related to depression and is a key pathophysiological process of depression. Triggering receptor expressed on myeloid cells 1 (TREM-1) has been proven to exert proinflammatory effects in various diseases. However, the role of TREM-1 in depression has not been elucidated.

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Effects of total sleep deprivation on sensorimotor gating in humans

Patrick Vizeli a,*, Bruna Cuccurazzu a,b, Sean P.A. Drummond c, Dean T. Acheson a,b, Victoria B. Risbrough

doi : 10.1016/j.bbr.2023.114487

Volume 449, 9 July 2023, 114487

Sensorimotor gating is a measure of pre-attentional information processing and can be measured by prepulse inhibition (PPI) of the startle reflex. Sleep deprivation has been shown to disrupt PPI in animals and humans, and has been proposed as an early phase 2 model to probe antipsychotic efficacy in heathy humans.

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