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RETINAL VASCULITIS OR VASCULAR OCCLUSION AFTER BROLUCIZUMAB FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: A Systematic Review of Real-World Evidence.
Wykoff, Charles C. MD, PhD *; Matsumoto, Hidetaka MD, PhD +; Barakat, Mark R. MD ++; Karcher, Helene PhD [S]; Lozama, Anthony PhD [P]; Mayhook, Andrew PhD **; Oshagbemi, Olorunfemi A. PhD [S]; Zorina, Olessia MSC [S]; Hassan, Tarek S. MD ++; Khanani, Arshad M. MD, MA ++++; Heier, Jeffrey S. MD [S][S]
doi : 10.1097/IAE.0000000000003769
Volume 43(7) pgs. 1051-1218,e37-e49 July 2023
Retinal vasculitis or vascular occlusion (RV/RO) have been reported after brolucizumab for neovascular age-related macular degeneration.
COMPLEMENT INHIBITION FOR GEOGRAPHIC ATROPHY: Review of Salient Functional Outcomes and Perspective.
Spaide, Richard F. MD *; Vavvas, Demetrios G. MD, PhD +
doi : 10.1097/IAE.0000000000003796
To evaluate available rationale and outcomes of randomized trial results for complement inhibition for geographic atrophy
OUTCOMES OF SWITCHING FROM PROACTIVE TO REACTIVE TREATMENT AFTER DEVELOPING ADVANCED CENTRAL NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.
Cornish, Elisa E. MBBS, PhD *; Nguyen, Vuong PhD *; Puzo, Martin MD +; O'Toole, Louise MD ++; Gemmy Cheung, Chui M. MBBS [S]; Vincent, Andrea MBChB, MD, FRANZCO [P]; Guillaumie, Tremeur MD **; Oei, Sioe Lan MD ++; Morros, Helena Brosa MD ++++; Barthelmes, Daniel MD, PhD *,[S][S]; Gillies, Mark C. MBBS, PhD *
doi : 10.1097/IAE.0000000000003771
We assessed outcomes of eyes with neovascular age-related macular degeneration (nAMD) that switched from proactive (treat-and-extend) to reactive (pro re nata) treatment regimen after developing macular atrophy (MA) or submacular fibrosis (SMFi).
SEVERE VISUAL LOSS DURING ANTI-VEGF INTRAVITREAL INJECTIONS IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: TIMING, PROGNOSIS, AND OPTICAL COHERENCE TOMOGRAPHY FINDINGS.
GRASSI, MARIA OLIVA MD; MONTELEONE, GIUSEPPINA MD; POZHARITSKIY, NIKOLAI MD; MOLFETTA, TERESA; BOSCIA, GIACOMO MD; ALESSIO, GIOVANNI MD; BOSCIA, FRANCESCO MD
doi : 10.1097/IAE.0000000000003774
Intravitreal injection (IVI) of anti-vascular endothelial growth factor (VEGF) is the standard of care for neovascular age-related macular degeneration (nAMD).
REAL WORLD STUDY COMPARING PHAKIC VERSUS PSEUDOPHAKIC EYES IN DIABETIC MACULAR EDEMA TREATED WITH DEXAMETHASONE IMPLANT: The PHAKIDEX Study.
Mathis, Thibaud MD, PhD *,+,++; Rezkallah, Amina MD *,+; Ricard, Cecile PhD [S]; Vartin, Cristina MD *; Abukhashabah, Amro MD *; Devin, Francois MD [P],**; Kodjikian, Laurent MD, PhD *,+,++
doi : 10.1097/IAE.0000000000003787
Dexamethasone implant (DEX-implant) is one treatment choice in diabetic macular edema. However, steroid-induced cataract is a common complication when treating a chronic disease and could lead to vision loss.
HENLE FIBER LAYER THICKNESS AND AREA MEASUREMENT IN TYPE 2 DIABETES MELLITUS WITH AND WITHOUT RETINOPATHY USING A MODIFIED DIRECTIONAL OPTICAL COHERENCE TOMOGRAPHY STRATEGY.
Ersoz, M. Giray MD *; K[latin dotless i]r[latin dotless i]k, Furkan MD +; Isik, Burcu MD *; Ozdemir, Hakan MD +
doi : 10.1097/IAE.0000000000003778
To investigate the thicknesses and areas of Henle fiber layer (HFL), outer nuclear layer, and outer plexiform layer in the eyes of patients with diabetes with no diabetic retinopathy, in eyes with nonproliferative diabetic retinopathy without diabetic macular edema, and in healthy eyes using a modified directional optical coherence tomography strategy.
ASSOCIATION OF OCULAR PERFUSION PRESSURE AND CEREBROSPINAL FLUID PRESSURE WITH CHANGES IN DIABETIC RETINOPATHY.
Lin, Zhong MD, PhD *; Li, Dong MD +; Wen, Liang MD +; Wang, Yu MD +; Wang, Feng Hua MD, PhD ++; Liang, Yuan Bo MD, PhD *
doi : 10.1097/IAE.0000000000003792
To investigate the association between mean ocular perfusion pressure (MOPP), estimated cerebrospinal fluid pressure (CSFP), and changes in diabetic retinopathy (DR) in a Northeastern Chinese population with Type 2 diabetes.
RECURRENT FLOATERS AFTER LIMITED VITRECTOMY FOR VISION DEGRADING MYODESOPSIA.
Boneva, Stefaniya K. MD *,+,++; Nguyen, Justin H. BA *; Gui, Wei MD *; Hoerig, Cameron PhD [S]; Mamou, Jonathan PhD [S]; Ketterling, Jeffrey A. PhD [S]; Chong, Lawrence P. MD *,[P]; Sebag, J. MD, FACS, FRCOphth, FARVO *,+,**
doi : 10.1097/IAE.0000000000003781
Limited vitrectomy improves vision degrading myodesopsia, but the incidence of recurrent floaters postoperatively is not known. We studied patients with recurrent central floaters using ultrasonography and contrast sensitivity (CS) testing to characterize this subgroup and identify the clinical profile of patients at risk of recurrent floaters.
PRIMARY MULTIPLE EVANESCENT WHITE DOT SYNDROME AND MULTIPLE EVANESCENT WHITE DOT SYNDROME SECONDARY TO MULTIFOCAL CHOROIDITIS/PUNCTATE INNER CHOROIDOPATHY: A Comparative Study.
Meng, Yang MD *; Zhang, Qi MD +; Li, Lu MD, PhD *; Yi, Zuohuizi MD, PhD *; Xu, Yishuang MD *; Su, Yu MD, PhD *; Liang, Congbi MD *; Xiao, Di MD *; Zhang, Lu MD ++; Chen, Changzheng MD PhD *
doi : 10.1097/IAE.0000000000003776
To present and compare the clinical features and multimodal imaging (MMI) findings of the primary form of multiple evanescent white dot syndrome (MEWDS) and MEWDS secondary to multifocal choroiditis/punctate inner choroidopathy (MFC/PIC).
RHOMBUS DEFORMATION OF RETINAL LATERAL DISPLACEMENT AFTER EPIRETINAL MEMBRANE REMOVAL REVEALED BY DIFFEOMORPHIC IMAGE REGISTRATION.
Honzawa, Koki MD; Horiguchi, Hiroshi MD, PhD; Terauchi, Ryo MD, PhD; Iida, Yuka MD; Katagiri, Satoshi MD, PhD; Gunji, Hisato MD, PhD; Nakano, Tadashi MD, PhD
doi : 10.1097/IAE.0000000000003775
To establish an analysis method using diffeomorphic image registration and evaluate microvascular displacement through epiretinal membrane (ERM) removal.
PATHOLOGIC STUDY OF UNTREATED INTRARETINAL GLIOSIS SURGICALLY EXCISED VIA PARS PLANA VITRECTOMY.
Wu, Mengai MD *; Ren, Xinyu MD, PhD +; Chen, Yan MD *; Chen, Lifeng MD *; Lian, Hengli MD *; Li, Haidong MD *; Li, Qiuming MD, PhD ++; Zheng, Bin MD, PhD *
doi : 10.1097/IAE.0000000000003777
To evaluate the pathologic process of intraretinal glioses by investigating mass tissues resected from untreated eyes with intraretinal glioses.
RISK FACTORS FOR SURGERY OR BLINDNESS IN NEOVASCULAR GLAUCOMA EYES TREATED WITH ANTI-VEGF INJECTIONS BY A RETINA SPECIALIST.
Massenzio, Erik MD *; Xu, David MD +; Abishek, Robert BA +; Wibbelsman, Turner D. BS *,+; Sheng, Young AB *; Obeid, Anthony MD, MPH +; Bhatt, Shivani BS +; Zhang, Qiang PhD, MPH ++; Sharpe, James MS ++; Park, Carl H. MD +; Spirn, Marc J. MD +; Gupta, Omesh P. MD, MBA +; Chiang, Allen MD +; Shukla, Aakriti MD [S]; Shalaby, Wesam S. MD, PhD [S]; Myers, Jonathan S. MD [S]; Hsu, Jason MD +
doi : 10.1097/IAE.0000000000003780
To determine baseline patient characteristics that predict the need for glaucoma surgery or blindness in eyes with neovascular glaucoma (NVG) despite intravitreal antivascular endothelial growth factor therapy.
TEMPORAL EFFICACY AND STERILITY TESTING OF POVIDONE-IODINE FROM AN OPEN BOTTLE.
Yousuf, Salman J. DO, MS *; Alfaqih, Murad BS +; Hicken, Rachel BS ++; Ramadan, Ali MD ++
doi : 10.1097/IAE.0000000000003783
To investigate the temporal efficacy and sterility of povidone-iodine (PI) against bacteria associated with postinjection endophthalmitis in an in vitro study.
MACULAR ATROPHY AND PHENOTYPIC VARIABILITY IN AUTOSOMAL DOMINANT STARGARDT-LIKE MACULAR DYSTROPHY DUE TO PROM1 MUTATION.
Ricca, Aaron M. MD *; Han, Ian C. MD *,+; HOFFMANN, JEREMY BS +; Stone, Edwin M. MD, PhD *,+; Sohn, Elliott H. MD *,+
doi : 10.1097/IAE.0000000000003784
To describe the phenotypic variability and rates of progression of atrophy in patients with PROM1-associated macular dystrophy. Methods: Patients in this retrospective, longitudinal case series from a tertiary center had clinical examination and multimodal imaging performed.
PENTOSAN POLYSULFATE SODIUM (ELMIRON) MACULOPATHY: A Genetic Perspective.
Kalaw, Fritz Gerald P. MD *,+; Ignacio, John Carlos I. PhD ++; Wu, Chris Y. MD *,+,[S]; Ferreyra, Henry MD *,+; Nudleman, Eric MD, PhD *,+; Baxter, Sally L. MD, MSc +,[P]; Freeman, William R. MD *,+; Borooah, Shyamanga MBBS, PhD *,+
doi : 10.1097/IAE.0000000000003794
To assess genetic associations for pentosan polysufate sodium maculopathy. Methods: Genetic testing for inherited retinal dystrophy genes using exome testing and for 14 age-related macular degeneration-associated single nucleotide polymorphisms (SNPs) using panel testing were performed. In addition, full-field electroretinograms (ffERG) were obtained to identify any cone-rod dystrophy.
EVALUATION OF OPTIC DISK AND MACULAR VASCULARITY CHANGES IN CRVO USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.
Yousif, Hussein MSc; Rashad, MOHAMMAD MD; Abdel Dayem, Hisham Khairy MD; Abdellatif, Mona K. MD
doi : 10.1097/IAE.0000000000003795
To quantify changes in optic disk and macular vasculature in patients with central retinal vein occlusion using optical coherence tomography angiography and detect its correlation with visual acuity.
LONG-TERM PROGRESSION PATTERN OF MYOPIC TRACTIONAL MACULOPATHY: Outcomes and Risk Factors.
Meng, Jiaqi MD *; Chen, Yuxi BS *; Cheng, Kaiwen BS *; Qi, Jiao MD *,+,++; Du, Yu MD *,+,++; Yao, Yunqian BS *,+,++; He, Wenwen MD *,+,++; Zhang, Keke MD *,+,++; Lu, Yi MD *,+,++; Zhu, Xiangjia MD *,+,++,[S]
doi : 10.1097/IAE.0000000000003791
To evaluate the long-term progression pattern of myopic tractional maculopathy and the risk factors. Methods: The prevalence and grade of myopic tractional maculopathy were assessed with optical coherence tomography at enrollment and at the 2-year follow-up.
Simple Bimanual Technique of Internal Limiting Membrane Retrieval.
Agarwal, Pulak MD; Venkatesh, Pradeep MD; Kumar, Vinod MS, FRCS
doi : 10.1097/IAE.0000000000002903
To describe a novel technique of internal limiting membrane retrieval. Methods: A 25-gauge vitrectomy was performed in all patients. After internal limiting membrane (ILM) peeling (after brilliant blue dye staining), the ILM was held with the forceps in the midvitreous cavity and a 25-gauge cannula mounted on a 2 mL of balanced salt solution-filled syringe was introduced.
Intrascleral Fixation of Flanged Polypropylene Suture(s) for Iridodialysis Repair.
Ou, Zhongmin PhD *; Zhang, Qi MD +; Jin, Haiying MD ++
doi : 10.1097/IAE.0000000000002904
We will describe a minimally invasive technique for the repair of iridodialysis, without conjunctival dissections, using intrasceral fixation of a 6-0 polypropylene suture with a flanged tip.
Sutureless and Equipment-Free Technique for Contact Lens Viewing System During Vitreoretinal Surgery.
Silpa-Archa, Sukhum MD, BBA
doi : 10.1097/IAE.0000000000002933
To report a sutureless and equipment-free technique for contact lens wide-angle viewing system during vitreoretinal surgery. Methods: A step-by-step procedure and a surgical video using this technique were proposed.
Shovel and Cut Technique: Beveled Vitrectomy Probes to Address Diabetic Tractional Retinal Detachments.
Gerardo, Gonzalez-Saldivar MD; Chow, David R. MD
Removal of Intraocular Foreign Bodies Using a Modified Flute Needle.
Chan, Yvonne Y. Y. MBBS, MRCS *; Liu, Shasha MBBS, MRCS *; Tang, Geoffrey C. H. MBBS, MRCS *; Cheung, Janice C. C. MBBS, FRCS +; Liu, Candice C. H. MBBS, MRCS *; Li, Kenneth K. W. FRCS, FRCOphth *,++
doi : 10.1097/IAE.0000000000002964
To describe the construction of a novel intraocular snare and evaluate its effectiveness in intraocular foreign body (IOFB) removal. Method: This is a retrospective consecutive case series.
Diagnostic and Therapeutic Challenges.
Menean, Matteo Drs.; Querques, Lea; Sacconi, Riccardo; Invernizzi, Alessandro; Boon, Camiel J. F.; Jampol, Lee M.; Bandello, Francesco; Querques, Giuseppe; Kim, Stephen J.
Multimodal Imaging and Functional Assessment in a Young Patient Presenting With Concomitant Unilateral Retinal Capillary Hemangioma and Presumed Retinal Pigment Epithelium Dysgenesis.
Romano, Francesco MD, FEBO; Preziosa, Chiara MD, FEBO; Staurenghi, Giovanni MD, FARVO; Pellegrini, Marco MD
Reply.
Mylonas, Georgios MD *; Haj Najeeb, Bilal PhD *; Goldbach, Felix MD *; Deak, Gabor G. PhD *; Michl, Martin MD *; Brugger, Jonas MSc +; Schmidt-Erfurth, Ursula MD *; Gerendas, Bianca S. PhD *
Reply.
Iwahashi, Chiharu MD *; Matsushita, Itsuka MD +; Kuniyoshi, Kazuki MD *; Kondo, Hiroyuki MD +; Kusaka, Shunji MD *
Reply.
Do, Jae Rock MD *; Park, Su Jin MD +; Kim, Jin Young MD *; Shin, Jae Pil MD, PhD *; Park, Dong Ho MD, PhD *,+
Reply.
Song, Yong-Yeon MD; Jun, Ji-Ho MD; Kim, Jung-Tae MD; Lee, Sung-Chul MD, PhD; Lee, Min-Woo MD, PhD
Correspondence.
Subramanian, Brughanya MOptom; Raman, Rajiv MS, DNB, FRCS; Ratra, Dhanashree MS, DNB, FRCS
