Rheumatology




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Rheumatoid arthritis: thinking and understanding disease through a broader lens

Elena Nikiphorou, Annelies Boonen

doi : 10.1093/rheumatology/kead011

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2333–2334

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Reading nailfold capillaroscopic images in systemic sclerosis: manual and/or automated detection?

Maurizio Cutolo, Emanuele Gotelli, Vanessa Smith

doi : 10.1093/rheumatology/keac630

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2335–2337

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SLE disease activity stabilizes over time: a hypothesis stimulated by a model reported a few years ago and recently re-tested

Ning Li

doi : 10.1093/rheumatology/kead029

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2338–2340

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A self-tracking tool for detecting chronic widespread pain in axial spondyloarthritis

Fabiola Atzeni, Alessandra Alciati

doi : 10.1093/rheumatology/kead045

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2341–2342

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Is Satoyoshi syndrome an autoimmune disease? A systematic review

Vinícius Viana Abreu Montanaro, Julián Solís-García del Pozo, Thiago Falcão Hora, Beatriz H León, Carlos de Cabo, Javier Solera

doi : 10.1093/rheumatology/kead067

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2343–2351

Satoyoshi syndrome is a rare multisystem disease of presumed autoimmune aetiology. We carried out a systematic review to evaluate the available evidence to support that autoimmune hypothesis.

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Therapeutic consequences in patients with both inflammatory rheumatic diseases and multiple sclerosis

Jean-Guillaume Letarouilly, Patrick Vermersch, René-Marc Flipo

doi : 10.1093/rheumatology/keac665

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2352–2359

Dealing with patients with both multiple sclerosis (MS) and inflammatory rheumatic disorders (IRDs) is not uncommon for a rheumatologist, as there is a statistical association between SpA and MS.

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Non-inflammatory pain in inflammatory arthritis

Dhivya Das, Ernest Choy

doi : 10.1093/rheumatology/keac671

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2360–2365

Non-inflammatory’ pain, pain that is not associated with measures of inflammation, is common in patients with inflammatory arthritis including RA. One important cause of non-inflammatory pain is concomitant fibromyalgia.

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COVID-19 vaccination in autoimmune diseases (COVAD) study: vaccine safety and tolerance in rheumatoid arthritis

R Naveen, Ioannis Parodis, Mrudula Joshi, Parikshit Sen, Julius Lindblom, Vishwesh Agarwal, James B Lilleker, Ai Lyn Tan, Arvind Nune, Samuel Katsuyuki Shinjo, Babur Salim, Nelly Ziade, Tsvetelina Velikova, Abraham Edgar Gracia-Ramos, Miguel A Saavedra, Jessica Day, Ashima Makol, Oliver Distler, Hector Chinoy, Vikas Agarwal, Rohit Aggarwal, Latika Gupta, Elena Nikiphorou, COVAD Study Group

doi : 10.1093/rheumatology/keac624

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2366–2376

The COVID-19 vaccination in autoimmune diseases (COVAD) study aimed to assess short-term COVID-19 vaccination-related adverse events (AEs) in RA patients.

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Methotrexate, leflunomide and tacrolimus use and the progression of rheumatoid arthritis-associated interstitial lung disease

Ji-Won Kim, Sang Wan Chung, Jung Yoon Pyo, Sung Hae Chang, Min Uk Kim, Chan Ho Park, Ji Sung Lee, Jeong Seok Lee, You-Jung Ha, Eun Ha Kang, Yeon-Ah Lee, Yong-Beom Park, Eun Young Lee, Jung-Yoon Choe

doi : 10.1093/rheumatology/keac651

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2377–2385

To examine the association between MTX, LEF and tacrolimus use and the progression of RA-associated interstitial lung disease (ILD).

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Disproportionate articular pain is a frequent phenomenon in rheumatoid arthritis and responds to treatment with sarilumab

Ernest Choy, Vivian Bykerk, Yvonne C Lee, Hubert van Hoogstraten, Kerri Ford, Amy Praestgaard, Serge Perrot, Janet Pope, Anthony Sebba

doi : 10.1093/rheumatology/keac659

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2386–2393

In some patients with RA, joint pain is more severe than expected based on the amount of joint swelling [referred to as disproportionate articular pain (DP)]. We assessed DP prevalence and the effects of sarilumab, an IL-6 inhibitor, on DP.

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Is the relationship between deprivation and outcomes in rheumatoid arthritis mediated by body mass index? A longitudinal cohort study

Rozemarijn Witkam, James M Gwinnutt, Jennifer Humphreys, Suzanne M M Verstappen, RAMS Co-Investigators

doi : 10.1093/rheumatology/keac662

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2394–2401

To understand the relationships between deprivation and obesity with self-reported disability and disease activity in people with RA, and to determine whether BMI mediates the relationship between area-level deprivation and these outcomes.

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Machine learning identifies a profile of inadequate responder to methotrexate in rheumatoid arthritis

Julien Duquesne, Vincent Bouget, Paul Henry Cournède, Bruno Fautrel, Francis Guillemin, Pascal H P de Jong, Judith W Heutz, Marloes Verstappen, Annette H M van der Helm-van Mil, Xavier Mariette, Samuel Bitoun

doi : 10.1093/rheumatology/keac645

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2402–2409

Around 30% of patients with RA have an inadequate response to MTX. We aimed to use routine clinical and biological data to build machine learning models predicting EULAR inadequate response to MTX and to identify simple predictive biomarkers.

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Anti-protein arginine deiminase antibodies are distinctly associated with joint and lung involvement in rheumatoid arthritis

Boaz Palterer, Gianfranco Vitiello, Marco Del Carria, Bernardo D’Onofrio, Laura Martinez-Prat, Michael Mahler, Daniele Cammelli, Paola Parronchi

doi : 10.1093/rheumatology/keac667

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2410–2417

RA is a chronic inflammatory disease in which possible interstitial lung disease (ILD) is an extra-articular manifestation that carries significant morbidity and mortality.

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Utility of nailfold capillary assessment for predicting psoriatic arthritis based on a prospective observational cohort study

Takemichi Fukasawa, Satoshi Toyama, Atsushi Enomoto, Asako Yoshizaki-Ogawa, Yuta Norimatsu, Shoko Tateishi, Hiroko Kanda, Kiyoshi Miyagawa, Shinichi Sato, Ayumi Yoshizaki

doi : 10.1093/rheumatology/keac664

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2418–2425

PsA is one of the most serious comorbidities associated with psoriasis. While the early intervention in PsA is demanded, risk factors of PsA development are not well-known. This is the first prospective study to evaluate the clinical significance of nailfold capillary (NFC) changes in patients with psoriasis.

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Treat-to-target urate-lowering therapy and hospitalizations for gout: results from a nationwide cohort study in England

Mark D Russell, Edward Roddy, Andrew I Rutherford, Benjamin Ellis, Sam Norton, Abdel Douiri, Martin C Gulliford, Andrew P Cope, James B Galloway

doi : 10.1093/rheumatology/keac638

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2426–2434

To investigate associations between treat-to-target urate-lowering therapy (ULT) and hospitalizations for gout.

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Elevated serum CA72-4 predicts gout flares during urate lowering therapy initiation: a prospective cohort study

Shuhui Hu, Mingshu Sun, Maichao Li, Xiaomei Xue, Robert Terkeltaub, Can Wang, Ming Wang, Jie Lu, Zijing Ran, Hailong Li, Aichang Ji, Wenyan Sun, Xinde Li, Yuwei He, Zhen Liu, Hui Zhang, Xuefeng Wang, Xiaopeng Ji, Nicola Dalbeth, Changgui Li

doi : 10.1093/rheumatology/keac656

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2435–2443

Gout flares during urate-lowering therapy (ULT) initiation are common, but predictors of these flares are poorly understood. The aim of this study was to determine whether serum CA72-4 is an independent predictor for gout flares during ULT initiation.

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The natural history of chronic widespread pain in patients with axial spondyloarthritis: a cohort study with clinical and self-tracking data

Anushka Soni, Revathi Nishtala, Stanley Ng, Rosemarie Barnett, Te-yuan Chyou, Charlotte Cavill, Raj Sengupta

doi : 10.1093/rheumatology/keac679

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2444–2452

This study investigates longitudinal patterns, predictors and long-term impact of pain in axial spondyloarthritis (axSpA), using clinical and self-tracking data.

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Safety and tolerance of vaccines against SARS-CoV-2 infection in systemic lupus erythematosus: results from the COVAD study

R Naveen, Elena Nikiphorou, Mrudula Joshi, Parikshit Sen, Julius Lindblom, Vishwesh Agarwal, James B Lilleker, Ai Lyn Tan, Babur Salim, Nelly Ziade, Tsvetelina Velikova, Abraham Edgar Gracia-Ramos, Masataka Kuwana, Jessica Day, Ashima Makol, Oliver Distler, Hector Chinoy, Lisa S Traboco, Suryo Anggoro Kusumo Wibowo, Erick Adrian Zamora Tehozol, Jorge Rojas Serrano, Ignacio García-De La Torre, COVAD Study Group , Rohit Aggarwal, Latika Gupta, Vikas Agarwal, Ioannis Parodis

doi : 10.1093/rheumatology/keac661

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2453–2463

To determine COVID-19 vaccine-related adverse events (AEs) in the seven-day post-vaccination period in patients with SLE vs autoimmune rheumatic diseases (AIRDs), non-rheumatic autoimmune diseases (nrAIDs), and healthy controls (HC).

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TGF-β3 in differentiation and function of Tph-like cells and its relevance to disease activity in patients with systemic lupus erythematosus

Yu Shan, Shingo Nakayamada, Aya Nawata, Kaoru Yamagata, Koshiro Sonomoto, Hiroaki Tanaka, Yurie Satoh-Kanda, Mai-Phuong Nguyen, Yasuyuki Todoroki, Atsushi Nagayasu, Masanobu Ueno, Ryuichiro Kanda, Yuya Fujita, Tong Zhang, He Hao, Jieqing Zhou, Xiaoxue Ma, Junpei Anan, Anh Phuong Nguyen, Yoshiya Tanaka

doi : 10.1093/rheumatology/keac646

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2464–2474

T peripheral helper (Tph) cells have major roles in pathological processes in SLE. We sought to clarify the mechanisms of Tph cell differentiation and their relevance to clinical features in patients with SLE.

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Preclinical ocular changes in systemic lupus erythematosus patients by optical coherence tomography

Laura Pelegrín, Montse Morató, Olga Araújo, Marc Figueras-Roca, Javier Zarranz-Ventura, Alfredo Adán, Ricard Cervera, Ricardo P Casaroli-Marano, Vanesa Budi, Lucía Barrera-López, José Ríos, José Hernández-Rodríguez, Gerard Espinosa

doi : 10.1093/rheumatology/keac626

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2475–2482

The aim of the present study was to detect preclinical changes in SLE patients in retinal microvascularization or retinal and optical nerve structure by optical coherence tomography.

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Sex influence on outcomes of patients with systemic sclerosis–associated interstitial lung disease: a EUSTAR database analysis

Corrado Campochiaro, Anna-Maria Hoffmann-Vold, Jerome Avouac, Jörg Henes, Jeska de Vries-Bouwstra, Vanessa Smith, Elise Siegert, Paolo Airò, Fahrettin Oksel, Raffaele Pellerito, Marie Vanthuyne, Maria Rosa Pozzi, Murat Inanc, Jean Sibilia, Armando Gabrielli, Oliver Distler, Yannick Allanore, EUSTAR Collaborators

doi : 10.1093/rheumatology/keac660

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2483–2491

Interstitial lung disease (ILD) is the leading cause of morbidity and mortality in systemic sclerosis (SSc) patients. We aimed to investigate the impact of sex on SSc-ILD.

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Vision transformer assisting rheumatologists in screening for capillaroscopy changes in systemic sclerosis: an artificial intelligence model

Alexandru Garaiman, Farhad Nooralahzadeh, Carina Mihai, Nicolas Perez Gonzalez, Nikitas Gkikopoulos, Mike Oliver Becker, Oliver Distler, Michael Krauthammer, Britta Maurer

doi : 10.1093/rheumatology/keac541

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2492–2500

The first objective of this study was to implement and assess the performance and reliability of a vision transformer (ViT)-based deep-learning model, an ‘off-the-shelf’ artificial intelligence solution, for identifying distinct signs of microangiopathy in nailfold capilloroscopy (NFC) images of patients with SSc. The second objective was to compare the ViT’s analysis performance with that of practising rheumatologists.

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Risk factors for lung function decline in systemic sclerosis-associated interstitial lung disease in a large single-centre cohort

Ahmad Ramahi, Alain Lescoat, David Roofeh, Vivek Nagaraja, Rajaie Namas, Suiyuan Huang, John Varga, David O’Dwyer, Bonnie Wang, Kevin Flaherty, Ella Kazerooni, Dinesh Khanna

doi : 10.1093/rheumatology/keac639

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2501–2509

The aim of this study was to identify risk factors of percent predicted forced vital capacity (ppFVC) decline in patients with SSc-associated interstitial lung disease (SSc-ILD).

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Microcirculation dynamics in systemic vasculitis: evidence of impaired microvascular response regardless of cardiovascular risk factors

Panagiotis Dolgyras, Antonios Lazaridis, Panagiota Anyfanti, Eleni Gavriilaki, Nikolaos Koletsos, Areti Triantafyllou, Barbara Nikolaidou, Vasiliki Galanapoulou, Stella Douma, Eugenia Gkaliagkousi

doi : 10.1093/rheumatology/keac652

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2510–2516

Systemic vasculitides (SVs) are a highly inflammatory group of diseases characterized by significant cardiovascular (CV) mortality. Microvascular damage closely linked with accelerated atherosclerosis and thrombosis represents a core pathophysiological mechanism contributing to the excess CV risk of patients with SVs.

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Ocular manifestations of ANCA-associated vasculitis

Mats L Junek, Lily Zhao, Stephanie Garner, David Cuthbertson, Christian Pagnoux, Curry L Koening, Carol A Langford, Carol A McAlear, Paul A Monach, Larry W Moreland, Rennie L Rhee, Philip Seo, Ulrich Specks, Antoine G Sreih, Kenneth Warrington, Michael E Wechsler, Peter A Merkel, Nader A Khalidi

doi : 10.1093/rheumatology/keac663

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2517–2524

ANCA-associated vasculitis (AAV) is a group of multisystem diseases that can have several ocular manifestations. There are published data on ocular manifestations of granulomatosis with polyangiitis (GPA), but few for eosinophilic granulomatosis with polyangiitis (EGPA) or microscopic polyangiitis (MPA).

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Changes in anti-MDA5 antibody titres and serum cytokine levels before and after diagnosis of anti-MDA5 antibody-positive dermatomyositis

Masahiro Kogami, Yoshiyuki Abe, Taiki Ando, Ayako Makiyama, Ken Yamaji, Naoto Tamura

doi : 10.1093/rheumatology/keac627

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2525–2533,

Anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive DM is characterized by rapidly progressive interstitial lung disease and has a poor prognosis. We aimed to investigate whether anti-MDA5 antibody titres and cytokine levels predict clinical course, and evaluate changes in both parameters before and after diagnosis.

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Type I interferon and neutrophil transcripts in lupus nephritis renal biopsies: clinical and histopathological associations

Clio P Mavragani, Kyriakos A Kirou, Surya V Seshan, Mary K Crow

doi : 10.1093/rheumatology/keac641

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2534–2538

To investigate the expression of type I IFN (IFN-I) and neutrophil transcripts in kidney tissue from patients with different classes of LN and their association with distinct clinical and histopathological features.

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Association between anti-SSSCA1 antibodies and cancer in systemic sclerosis

Rachel S Wallwork, Ami A Shah, Livia Casciola-Rosen

doi : 10.1093/rheumatology/keac614

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2539–2543,

To define the clinical phenotype of SSc patients with antibodies against Sjogren’s syndrome (SS)/scleroderma autoantigen 1 (SSSCA1), and to examine the association between these antibodies and cancer in SSc patients.

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Rituximab-treated rheumatic patients: B cells predict seroconversion after COVID-19 boost or revaccination in initial vaccine non-responders

Christian Ammitzbøll, Marianne Kragh Thomsen, Jakob Bøgh Andersen, Jens Magnus Berth Jensen, Marie-Louise From Hermansen, Anders Dahl Johannsen, Mads Lamm Larsen, Clara Elbæk Mistegaard, Susan Mikkelsen, Fruzsina Szabados, Signe Risbøl Vils, Christian Erikstrup, Ellen-Margrethe Hauge, Anne Troldborg

doi : 10.1093/rheumatology/keac666

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2544–2549

To investigate the effect of either a booster vaccine (one dose) or revaccination (two doses 3 weeks apart) on the antibody response to the COVID-19 mRNA vaccines in patients with rheumatic disease (RD) treated with rituximab (RTX) who had not produced vaccine-reactive antibodies after the initial two vaccine doses. Further, to examine if B cell levels in peripheral blood predicted seroconversion.

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Beneficial effects of nintedanib on cardiomyopathy in patients with systemic sclerosis: a pilot study

Keita Ninagawa, Masaru Kato, Satonori Tsuneta, Suguru Ishizaka, Hideyuki Ujiie, Ryo Hisada, Michihito Kono, Yuichiro Fujieda, Yoichi M Ito, Tatsuya Atsumi Author Notes

doi : 10.1093/rheumatology/keac674

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2550–2555

Nintedanib is an inhibitor of tyrosine kinases that has been shown to slow the progression of interstitial lung disease (ILD), including ILD associated with SSc. The aim of this study was to explore the effect of nintedanib on cardiomyopathy associated with systemic sclerosis (SSc).

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Symptomatic myopathies in sarcoidosis: disease spectrum and myxovirus resistance protein A expression

Pitcha Chompoopong, Michael P Skolka, Floranne C Ernste, Margherita Milone, Teerin Liewluck

doi : 10.1093/rheumatology/keac668

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2556–2562

Symptomatic myopathy in sarcoidosis patients is not always due to sarcoid myopathy (ScM). We investigated the clinical and pathological spectrum including myxovirus resistance protein A (MxA) expression among sarcoidosis patients.

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Inhibitor of apoptosis proteins antagonist SM164 ameliorates experimental MPO-ANCA-associated vasculitis via enhancing fatty acid oxidation in neutrophils

Luo-Yi Wang, Rui-Xue Wang, Chen Wang, Su-Fang Chen, Xiao-Jing Sun, Zhi-Ying Li, Min Chen, Mark A Little, Ming-Hui Zhao

doi : 10.1093/rheumatology/keac621

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2563–2573

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of life-threatening autoimmune diseases. Inhibitors of apoptosis proteins (IAPs) are a class of molecules engaged in cell death and inflammation, interventions of which are proven effective in a number of inflammatory diseases.

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Deep stratification by transcriptome molecular characters for precision treatment of patients with systemic lupus erythematosus

Jun Qiao, Sheng-Xiao Zhang, Min-Jing Chang, Rong Zhao, Shan Song, Jia-Wei Hao, Can Wang, Jing-Xi Hu, Chong Gao, Cai-Hong Wang, Xiao-Feng Li

doi : 10.1093/rheumatology/keac625

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2574–2584

To leverage the high clinical heterogeneity of systemic lupus erythematosus (SLE), we developed and validated a new stratification scheme by integrating genome-scale transcriptomic profiles to identify patient subtypes sharing similar transcriptomic markers and drug targets.

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B-cell receptor profiling before and after IVIG monotherapy in newly diagnosed idiopathic inflammatory myopathies

Dornatien C Anang, Hannah A W Walter, Johan Lim, Ilse Niewold, Linda van der Weele, Eleonora Aronica, Filip Eftimov, Joost Raaphorst, Barbera D C van Schaik, Antoine H C van Kampen, Anneke J van der Kooi, Niek de Vries

doi : 10.1093/rheumatology/keac602

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2585–2593

To unravel B-cell receptor (BcR) characteristics in muscle tissues and peripheral blood and gain more insight into BcR repertoire changes in peripheral blood in idiopathic inflammatory myopathies (IIMs), and study how this correlates to the clinical response to IVIG.

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CCL24, CXCL9 and CXCL10 are increased in synovial fluid in patients with juvenile idiopathic arthritis requiring advanced treatment

Lina Al-Jaberi, Megan M Simonds, Anne Marie C Brescia

doi : 10.1093/rheumatology/keac617

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2594–2600

Oligoarticular JIA disease progression and outcomes are variable. Our objective is to detect protein markers that would allow for earlier intervention to potentially halt disease progression. In this retrospective study of serial SF samples, elevated expression of CCL24, CXCL9 and CXCL10 was linked to the eventual need for advanced medications.

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Anti-rituximab antibodies demonstrate neutralizing capacity, associate with lower circulating drug levels and earlier relapse in lupus

Chris Wincup, Nicky Dunn, Caroline Ruetsch-Chelli, Ali Manouchehrinia, Nastya Kharlamova, Meena Naja, Barbara Seitz-Polski, David A Isenberg, Anna Fogdell-Hahn, Coziana Ciurtin, Elizabeth C Jury

doi : 10.1093/rheumatology/keac608

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2601–2610

High rates of anti-drug antibodies (ADA) to rituximab have been demonstrated in patients undergoing treatment for SLE. However, little is known with regard to their long-term dynamics, impact on drug kinetics and subsequent implications for treatment response. In this study, we aimed to evaluate ADA persistence over time, impact on circulating drug levels, assess clinical outcomes and whether they are capable of neutralizing rituximab.

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Rheumatoid arthritis macrophages are primed for inflammation and display bioenergetic and functional alterations

Megan M Hanlon, Trudy McGarry, Viviana Marzaioli, Success Amaechi, Qingxuan Song, Sunil Nagpal, Douglas J Veale, Ursula Fearon

doi : 10.1093/rheumatology/keac640

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2611–2620

Myeloid cells with a monocyte/macrophage phenotype are present in large numbers in the RA joint, significantly contributing to disease; however, distinct macrophage functions have yet to be elucidated. This study investigates the metabolic activity of infiltrating polarized macrophages and their impact on pro-inflammatory responses in RA.

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HOXA5 is a key regulator of class 3 semaphorins expression in the synovium of rheumatoid arthritis patients

Sara Martínez-Ramos, Carlos Rafael-Vidal, Beatriz Malvar-Fernández, Angela Rodriguez-Trillo, Douglas Veale, Ursula Fearon, Carmen Conde, Javier Conde-Aranda, Timothy R D J Radstake, Jose María Pego-Reigosa, Kris A Reedquist, Samuel García

doi : 10.1093/rheumatology/keac654

Rheumatology, Volume 62, Issue 7, July 2023, Pages 2621–2630

Class 3 semaphorins are reduced in the synovial tissue of RA patients and these proteins are involved in the pathogenesis of the disease. The aim of this study was to identify the transcription factors involved in the expression of class 3 semaphorins in the synovium of RA patients.

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Correction to: Standardized nailfold capillaroscopy in children with rheumatic diseases: a worldwide study

doi : 10.1093/rheumatology/kead113

Rheumatology, Volume 62, Issue 7, July 2023, Page 2631

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Retraction to: CD8+CD103+ iTregs inhibit the progression of lupus nephritis by attenuating glomerular endothelial cell injury

doi : 10.1093/rheumatology/keac536

Rheumatology, Volume 62, Issue 7, July 2023, Page 2632

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Rituximab in myositis: where are we now? A survey of current usage

Tatiana Oliveira, Reşit Yıldırım, Claire Deakin, David Isenberg

doi : 10.1093/rheumatology/kead010

Rheumatology, Volume 62, Issue 7, July 2023, Pages e211–e212

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Anti-Ku antibody syndrome: is it a distinct clinical entity? A cross-sectional study of 75 patients

Marlene Sousa, Patrícia Martins, Bernardo Santos, Emanuel Costa, Filipe Cunha Santos, Raquel Freitas, Margarida Faria, Frederico Martins, Teresa Rodrigues, Tânia Santiago, José A P Silva, Luís S Inês

doi : 10.1093/rheumatology/kead049

Rheumatology, Volume 62, Issue 7, July 2023, Pages e213–e215

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Detection of anti-eIF2B autoantibodies in systemic sclerosis by immunoprecipitation-mass spectrometry

Jean-Baptiste Vulsteke, Frédéric Coutant, David Goncalves, Benoit Nespola, Petra De Haes, Wim A Wuyts, Daniel Blockmans, Ellen De Langhe, Nicole Fabien, Xavier Bossuyt

doi : 10.1093/rheumatology/kead060

Rheumatology, Volume 62, Issue 7, July 2023, Pages e216–e218

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Type 1 CRPS isolated to one digit and with localized osteopenia

Claire Lloyd-Davies, Nicholas Shenker

doi : 10.1093/rheumatology/keac684

Rheumatology, Volume 62, Issue 7, July 2023, Pages e219–e220

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Diagnosing Camurati–Engelmann disease—the age of whole-exome sequencing

Deepak Nagra, Mark D Russell, Edward Alveyn, Surinder S Birring, David Elias, Sathiyaa Balachandran, James B Galloway

doi : 10.1093/rheumatology/keac670

Rheumatology, Volume 62, Issue 7, July 2023, Pages e221–e222

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Ruxolitinib rescued the macrophage activation syndrome in adult-onset Still’s disease with delayed hypersensitivity reaction to tocilizumab

Yakai Fu, Jia Li, Antao Xu, Jie Chen, Xiaodong Wang, Shuang Ye

doi : 10.1093/rheumatology/keac694

Rheumatology, Volume 62, Issue 7, July 2023, Pages e223–e225

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A systemic sclerosis disease model: can inducible pluripotent stem cells fill an unmet need in defining vascular leak?

Tracy M Frech, Colin Maguire, Aaron C Petrey, Gregory J Stoddard, Anthony J Donato

doi : 10.1093/rheumatology/keac719

Rheumatology, Volume 62, Issue 7, July 2023, Pages e226–e228

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Comment on: Whole grain consumption and risk of radiographic knee osteoarthritis: a prospective study from the Osteoarthritis Initiative

Roshni Lachmipersad, Leon de Prez, Anne Kamps, Jos Runhaar

doi : 10.1093/rheumatology/kead040

Rheumatology, Volume 62, Issue 7, July 2023, Pages e229–e230

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Comment on: Women in rheumatology: major contributions and key discoveries of the twentieth century

Ihsane Hmamouchi, Adewale Adebajo

doi : 10.1093/rheumatology/kead146

Rheumatology, Volume 62, Issue 7, July 2023, Page e231

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Comment on: Women in rheumatology: major contributions and key discoveries of the twentieth century: reply

Alla Ishchenko

doi : 10.1093/rheumatology/kead145

Rheumatology, Volume 62, Issue 7, July 2023, Page e232

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Refractory SAPHO syndrome involving the ilium

Fei Sun, Jian Zhu

doi : 10.1093/rheumatology/keac701

Rheumatology, Volume 62, Issue 7, July 2023, Pages e233–e234

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Evaluation of asymptomatic cerebral ischemia by arterial spin-labeling magnetic resonance imaging of the brain in Takayasu arteritis

Katsuhide Kusaka, Shingo Nakayamada, Shigeru Iwata, Yoshiya Tanaka

doi : 10.1093/rheumatology/keac720

Rheumatology, Volume 62, Issue 7, July 2023, Pages e235–e236

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