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Endocrine Health and Health Care Disparities in the Pediatric and Sexual and Gender Minority Populations: An Endocrine Society Scientific Statement
Alicia M Diaz-Thomas, Sherita Hill Golden, Dana M Dabelea, Adda Grimberg, Sheela N Magge, Joshua D Safer, Daniel E Shumer, Fatima Cody Stanford
doi : 10.1210/clinem/dgad124
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1533–1584
Endocrine care of pediatric and adult patients continues to be plagued by health and health care disparities that are perpetuated by the basic structures of our health systems and research modalities, as well as policies that impact access to care and social determinants of health.
Aggressive Pituitary Tumors and Pituitary Carcinomas: From Pathology to Treatment
Pia Burman, Olivera Casar-Borota, Luis Gustavo Perez-Rivas, Olaf M Dekkers
doi : 10.1210/clinem/dgad098
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1585–1601
Aggressive pituitary tumors (APTs) and pituitary carcinomas (PCs) are heterogeneous with regard to clinical presentation, proliferative markers, clinical course, and response to therapy. Half of them show an aggressive course only many years after the first apparently benign presentation. APTs and PCs share several properties, but a Ki67 index greater than or equal to 10% and extensive p53 expression are more prevalent in PCs.
Thyroid Hormone Receptor-β Agonists in NAFLD Therapy: Possibilities and Challenges
Limei Li, Yan Song, Yongquan Shi, Liangliang Sun
doi : 10.1210/clinem/dgad072
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1602–1613
Nonalcoholic fatty liver disease (NAFLD) is a progressive metabolic liver disease with an unknown pathogenesis and no FDA-approved drug treatment to date. Hypothyroidism has been identified as a risk factor for NAFLD as thyroxine is required for regulating metabolism in adults.
The Artificial Pancreas and Type 1 Diabetes
Munachiso Nwokolo, Roman Hovorka
doi : 10.1210/clinem/dgad068
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1614–1623
Diabetes technologies represent a paradigm shift in type 1 diabetes care. Continuous subcutaneous insulin infusion (CSII) pumps and continuous glucose monitors (CGM) improve glycated hemoglobin (HbA1c) levels, enhance time in optimal glycemic range, limit severe hypoglycemia, and reduce diabetes distress.
The Stanniocalcin-PAPP-A-IGFBP-IGF Axis
Claus Oxvig, Cheryl A Conover
doi : 10.1210/clinem/dgad053
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1624–1633
The pappalysin metalloproteinases, PAPP-A and PAPP-A2, have emerged as highly specific proteolytic enzymes involved in the regulation of insulin-like growth factor (IGF) signaling. The only known pappalysin substrates are a subset of the IGF binding proteins (IGFBPs), which bind IGF-I or IGF-II with high affinity to antagonize receptor binding.
Impaired Physical Performance in X-linked Hypophosphatemia Is not Caused by Depleted Muscular Phosphate Stores
Johannes Alexander Serhan Kara, Jochen Zange, Fabian Hoffman, Jens Tank, Jens Jordan, Oliver Semler, Eckhard Schönau, Jörn Rittweger, Lothar Seefried
doi : 10.1210/clinem/dgad210
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1634–1645
X-linked hypophosphatemia (XLH) is a rare genetic disease, characterized by renal phosphate wasting and complex musculoskeletal manifestations including decreased physical performance.
Novel MKRN3 Missense Mutations Associated With Central Precocious Puberty Reveal Distinct Effects on Ubiquitination
John C Magnotto, Alessandra Mancini, Keisha Bird, Luciana Montenegro, Filiz Tütüncüler, Sidney A Pereira, Vitoria Simas, Leonardo Garcia, Stephanie A Roberts, Delanie Macedo, Melissa Magnuson, Priscila Gagliardi, Nelly Mauras, Selma F Witchel, Rona S Carroll, Ana Claudia Latronico, Ursula B Kaiser, Ana Paula Abreu
doi : 10.1210/clinem/dgad151
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1646–1656
Loss-of-function mutations in the maternally imprinted genes, MKRN3 and DLK1, are associated with central precocious puberty (CPP). Mutations in MKRN3 are the most common known genetic etiology of CPP.
Nomogram for Predicting Intraoperative Hemodynamic Instability in Patients With Normotensive Pheochromocytoma
Yingshu Liu, Chao Liu, Yao Wang, Shen Li, Xinyu Li, Xuhan Liu, Bing Wang, Zuowei Pei, Linfeng Li, Lu Lin, Jianchang Qu, Kang Chen, Li Zang, Weijun Gu, Yiming Mu, Zhaohui Lyu, Jingtao Dou, Zhengnan Gao
doi : 10.1210/clinem/dgad024
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1657–1665
Intraoperative hemodynamic instability (HI) deteriorates surgical outcomes of patients with normotensive pheochromocytoma (NP).
Endocrine Responses to Triptorelin in Healthy Women, Women With Polycystic Ovary Syndrome, and Women With Hypothalamic Amenorrhea
Ali Abbara, Maria Phylactou, Pei Chia Eng, Sophie A Clarke, Toan D Pham, Tuong M Ho, Kah Yan Ng, Edouard G Mills, Kate Purugganan, Tia Hunjan, Rehan Salim, Alexander N Comninos, Lan N Vuong, Waljit S Dhillo
doi : 10.1210/clinem/dgad026
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1666–1675
Limited data exist regarding whether the endocrine response to the gonadotropin-releasing hormone receptor agonist (GnRHa) triptorelin differs in women with polycystic ovary syndrome (PCOS) compared with healthy women or those with hypothalamic amenorrhea (HA).
Diazoxide Choline Extended-Release Tablet in People With Prader-Willi Syndrome: A Double-Blind, Placebo-Controlled Trial
Jennifer L Miller, Evelien Gevers, Nicola Bridges, Jack A Yanovski, Parisa Salehi, Kathryn S Obrynba, Eric I Felner, Lynne M Bird, Ashley H Shoemaker, Moris Angulo ... Show more
doi : 10.1210/clinem/dgad014
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1676–1685
Prader-Willi syndrome (PWS) is a rare neurobehavioral-metabolic disease caused by the lack of paternally expressed genes in the chromosome 15q11-q13 region, characterized by hypotonia, neurocognitive problems, behavioral difficulties, endocrinopathies, and hyperphagia resulting in severe obesity if not controlled.
Effect of Oral Contraception on Screening Tests for Primary Aldosteronism: A 10-Year Longitudinal Study
Jun Yang, Stella May Gwini, Lawrence J Beilin, Markus Schlaich, Michael Stowasser, Morag J Young, Peter J Fuller, Trevor A Mori
doi : 10.1210/clinem/dgad010
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1686–1695
Primary aldosteronism (PA) and oral contraception (OC) can both cause hypertension in young women. However, the effect of OC on the screening test for PA, the aldosterone to renin ratio (ARR), is not clear.
Intranasal Carbetocin Reduces Hyperphagia, Anxiousness, and Distress in Prader-Willi Syndrome: CARE-PWS Phase 3 Trial
Elizabeth Roof, Cheri L Deal, Shawn E McCandless, Ronald L Cowan, Jennifer L Miller, Jill K Hamilton, Elizabeth R Roeder, Shana E McCormack, Tamanna R Roshan Lal, Hussein D Abdul-Latif, Andrea M Haqq, Kathryn S Obrynba, Laura C Torchen, Alaina P Vidmar, David H Viskochil, Jean-Pierre Chanoine, Carol K L Lam, Melinda J Pierce, Laurel L Williams, Lynne M Bird, Merlin G Butler, Diane E Jensen, Susan E Myers, Oliver J Oatman, Charumathi Baskaran, Laura J Chalmers, Cary Fu, Nathalie Alos, Scott D McLean, Ajay Shah, Barbara Y Whitman, Brent A Blumenstein, Sarah F Leonard, Jessica P Ernest, Joseph W Cormier, Sara P Cotter, Davis C Ryman
doi : 10.1210/clinem/dgad015
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1696–1708
Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by endocrine and neuropsychiatric problems including hyperphagia, anxiousness, and distress. Intranasal carbetocin, an oxytocin analog, was investigated as a selective oxytocin replacement therapy.
Sex Hormones and Diabetes in 45- to 74-year-old Men and Postmenopausal Women: The Hispanic Community Health Study
Victoria Persky, Chibuzor Abasilim, Konstantina Tsintsifas, Tessa Day, Robert M Sargis, Martha L Daviglus, Jianwen Cai, Sally Freels, Terry Unterman, Noel Chavez, Robert Kaplan, Carmen R Isasi, Amber Pirzada, Michelle L Meyer, Gregory A Talavera, Bharat Thyagarajan, Brandilyn A Peters, Jessica M Madrigal, Arielle Grieco, Mary E Turyk
doi : 10.1210/clinem/dgad018
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1709–1726
Previous studies demonstrated associations of endogenous sex hormones with diabetes. Less is known about their dynamic relationship with diabetes progression through different stages of the disease, independence of associations, and role of the hypothalamic-pituitary gonadal axis.
Effects of Hypocaloric Low-Fat, Ketogenic, and Ketogenic and Ketone Supplement Diets on Aldosterone and Renin
Paul Belany, Madison L Kackley, Songzhu Zhao, Bjorn Kluwe, Alex Buga, Christopher D Crabtree, Divya Nedungadi, David Kline, Guy Brock, Orlando P Simonetti, Jeff S Volek, Joshua J Joseph
doi : 10.1210/clinem/dgad009
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1727–1739
Ketogenic diets (KDs) and low-fat diets (LFD) result in similar weight loss, but have differential cardiometabolic effects on lipids and insulin. Generally, weight loss decreases renin–angiotensin–aldosterone system (RAAS) activity.
Predictors of Metformin Failure: Repurposing Electronic Health Record Data to Identify High-Risk Patients
Suzette J Bielinski, Licy L Yanes Cardozo, Paul Y Takahashi, Nicholas B Larson, Alexandra Castillo, Alana Podwika, Eleanna De Filippis, Valentina Hernandez, Gouri J Mahajan, Crystal Gonzalez, Shubhangi, Paul A Decker, Jill M Killian, Janet E Olson, Jennifer L St. Sauver, Pankaj Shah, Adrian Vella, Euijung Ryu, Hongfang Liu, Gailen D Marshall, James R Cerhan, Davinder Singh, Richard L Summers
doi : 10.1210/clinem/dgac759
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1740–1746
Metformin is the first-line drug for treating diabetes but has a high failure rate.
Longitudinal Trajectory and Early Life Determinant of Childhood Adipokines: Findings From a Racially Diverse Birth Cohort
Kartikeya Makker, Mingyu Zhang, Guoying Wang, Xiumei Hong, Khyzer Aziz, Tammy M Brady, Xiaobin Wang
doi : 10.1210/clinem/dgad005
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1747–1757
Leptin and adiponectin play important roles in systemic metabolic homeostasis, beginning in utero. Limited data exist on the levels and trajectories of these 2 hormones at birth and in childhood and their biological and social determinants.
Clinical and Genetic Characterization of Familial Central Precocious Puberty
Flávia Rezende Tinano, Ana Pinheiro Machado Canton, Luciana R Montenegro, Andrea de Castro Leal, Aline G Faria, Carlos E Seraphim, Raja Brauner, Alexander A Jorge, Berenice B Mendonca, Jesús Argente, Vinicius N Brito, Ana Claudia Latronico
doi : 10.1210/clinem/dgac763
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1758–1767
Central precocious puberty (CPP) can have a familial form in approximately one-quarter of the children. The recognition of this inherited condition increased after the identification of autosomal dominant CPP with paternal transmission caused by mutations in the MKRN3 and DLK1 genes.
Genomic Profiling Reveals the Variant Landscape of Sporadic Parathyroid Adenomas in Chinese Population
Xiaohui Tao, Tian Xu, Xiaoyun Lin, Shuqin Xu, Youben Fan, Bomin Guo, Xianzhao Deng, Qiong Jiao, Lihui Chen, Zhe Wei, Chengkun Chen, Wendi Yang, Zhenlin Zhang, Xiangtian Yu, Hua Yue
doi : 10.1210/clinem/dgad002
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1768–1775
Genotypic and Phenotypic Spectrum and Pathogenesis of WNT1 Variants in a Large Cohort of Patients With OI/Osteoporosis
Jing Hu, Xiaoyun Lin, Peng Gao, Qian Zhang, Bingna Zhou, Ou Wang, Yan Jiang, Weibo Xia, Xiaoping Xing, Mei Li
doi : 10.1210/clinem/dgac752
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1776–1786
Mutations in WNT1 can cause rare inherited disorders such as osteogenesis imperfecta (OI) and early-onset osteoporosis (EOOP). Owing to its rarity, the clinical characteristics and pathogenic mechanism of WNT1 mutations remain unclear.
Approach to the Patient: Pharmacological Therapies for Fracture Risk Reduction in Adults With Osteogenesis Imperfecta
Winnie Liu, Brendan Lee, Sandesh C S Nagamani, Lindsey Nicol, Frank Rauch, Eric T Rush, V Reid Sutton, Eric Orwoll
doi : 10.1210/clinem/dgad035
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1787–1796
Osteogenesis imperfecta (OI) is a genetic disorder characterized by increased bone fragility largely caused by defects in structure, synthesis, or post-translational processing of type I collagen. The effectiveness of medications used for fracture reduction in adults with OI is understudied and practice recommendations are not well established.
Approach to the Patient: Preventing Adrenal Crisis Through Patient and Clinician Education
Alexandra Ahmet, Anshu Gupta, Janine Malcolm, Cathrine Constantacos
doi : 10.1210/clinem/dgad003
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1797–1805
Adrenal crisis continues to be an important cause of death despite being a preventable condition. Significant deficits in patient education in the prevention of adrenal crisis have been identified as a contributor to adrenal crisis risk, despite the importance of patient education being highlighted in international guidelines.
GLP-1 Receptor Agonists and Risk of Adverse Cerebrovascular Outcomes in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Mainak Banerjee, Rimesh Pal, Satinath Mukhopadhyay, Kirthana Nair
doi : 10.1210/clinem/dgad076
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1806–1812
The effect of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on ischemic/hemorrhagic stroke and transient ischemic attacks (TIA) in type 2 diabetes mellitus (T2DM) remains undetermined.
Prevalence of Functioning Adrenal Incidentalomas: A Systematic Review and Meta-analysis
Elisa Sconfienza, Martina Tetti, Vittorio Forestiero, Franco Veglio, Paolo Mulatero, Silvia Monticone
doi : 10.1210/clinem/dgad044
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1813–1823
Adrenal hyperfunction is associated with an increased risk of cardiometabolic complications in subjects with adrenal incidentaloma (AI). Reliable prevalence estimates of functioning AIs are important to direct resources allocations.
The Effect of Early Time-Restricted Eating vs Later Time-Restricted Eating on Weight Loss and Metabolic Health
Juanhong Liu, Pan Yi, Feng Liu
doi : 10.1210/clinem/dgad036
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages 1824–1834
It remains controversial whether the choice of the daily eating window early or later in time-restricted eating (TRE) intervention (early or later TRE) has different effects on weight loss and metabolic health.
Effects of Maternal Exercise Modes on Glucose and Lipid Metabolism in Offspring Stem Cells
Filip Jevtovic, Donghai Zheng, Joseph A Houmard, Polina M Krassovskaia, Christian A Lopez, Breanna L Wisseman, Dylan M Steen, Nicholas T Broskey, Christy Isler, Jim DeVente, Xiangming Fang, Linda E May
doi : 10.1210/clinem/dgad059
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e360–e370
Maternal exercise positively influences pregnancy outcomes and metabolic health in progeny; however, data regarding the effects of different modes of prenatal exercise on offspring metabolic phenotype is lacking.
Low Bone Turnover Associates With Lower Insulin Sensitivity in Newly Diagnosed Drug-Naïve Persons With Type 2 Diabetes
Mohamad I Nasser, Jacob V Stidsen, Kurt Højlund, Jens Steen Nielsen, Richard Eastell, Morten Frost
doi : 10.1210/clinem/dgad043
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e371–e379
Bone turnover markers (BTMs) are lower in type 2 diabetes mellitus (T2D). The relationships between bone turnover, β-cell function, and insulin sensitivity in T2D are uncertain.
Increased Morbidity in Males Diagnosed With Gynecomastia: A Nationwide Register-based Cohort Study
Cecilie S Uldbjerg, Youn-Hee Lim, Elvira V Bräuner, Anders Juul
doi : 10.1210/clinem/dgad048
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e380–e387
Evidence on the long-term and general health of males with gynecomastia is lacking.
Racial/Ethnic Inequities in Use of Diabetes Technologies Among Medicare Advantage Beneficiaries With Type 1 Diabetes
Mallika Kommareddi, Kael Wherry, Robert A Vigersky
doi : 10.1210/clinem/dgad046
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e388–e395
Racial/ethnic inequities have been observed in diabetes care.
Association of Thyroid-Stimulating Hormone With All-Cause Mortality: A 2-Sample Mendelian Randomization Study
Yeqing Gu, Zimin Song, Qingkui Li, Jinhan Wang, Yanqi Song, Ge Meng, Hongmei Wu, Shunming Zhang, Xuena Wang, Juanjuan Zhang, Xinran Lu, Qiang Liu, Tao Huang, Jian Yang, Kaijun Niu
doi : 10.1210/clinem/dgad025
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e396–e403
Thyroid-stimulating hormone (TSH), as the most sensitive and specific marker of thyroid status, is associated with multiple health outcomes, including mortality. However, whether TSH levels are causally associated with the risk of mortality remains unclear.
HLA Class I Association With Autoimmune Diabetes in Chinese People: Distinct Implications in Classic Type 1 Diabetes and LADA
Ying Xia, Yan Chen, Xia Li, Shuoming Luo, Jian Lin, Gan Huang, Yang Xiao, Zhiying Chen, Zhiguo Xie, Zhiguang Zhou
doi : 10.1210/clinem/dgad006
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e404–e414
We aimed to investigate whether human leukocyte antigen (HLA) Class I loci differentially modulated the risk for and clinical features of Chinese people with classic type 1 diabetes (T1D) and latent autoimmune diabetes in adults (LADA).
Sex Differences in Long-Term Safety and Tolerability of GH Replacement Therapy in GH Deficient Adults
Tessa N A Slagboom, Christa C van Bunderen, Aart Jan van der Lely, Madeleine L Drent
doi : 10.1210/clinem/dgad013
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e415–e424
Previous studies report that outcomes of growth hormone (GH) replacement therapy (GHRT) might be less beneficial in growth hormone deficient (GHD) women compared with men.
Serum Mac-2 Binding Protein Glycosylation Isomer Concentrations Are Associated With Incidence of Type 2 Diabetes
Mayu Higashioka, Yoichiro Hirakawa, Jun Hata, Takanori Honda, Satoko Sakata, Mao Shibata, Takanari Kitazono, Haruhiko Osawa, Toshiharu Ninomiya
doi : 10.1210/clinem/dgad011
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e425–e433
Serum Mac-2 binding protein glycosylation isomer (M2BPGi) concentrations are known to be an indicator of chronic liver injury and fibrosis.
Impact of Thyroid Function on the Prevalence and Mortality of Metabolic Dysfunction-Associated Fatty Liver Disease
Yu-ling Chen, Shen Tian, Juan Wu, Hao Li, Shu Li, Zhou Xu, Xin-yu Liang, Vishnu Prasad Adhikari, Jun Xiao, Jing-yu Song, Chen-yu Ma, Rui-ling She, Zhao-xing Li, Kai-nan Wu, Ling-quan Kong
doi : 10.1210/clinem/dgad016
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e434–e443,
Thyroid function variation within the thyroxine reference range has negative metabolic effects. Metabolic dysfunction-associated fatty liver disease (MAFLD) is a recently proposed definition.
Hemoglobin A1c Variability Metrics Predict Coronary Artery Calcium and Cardiovascular Events in Type 1 Diabetes: The CACTI Study
William B Horton, Janet K Snell-Bergeon
doi : 10.1210/clinem/dgad019
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e444–e449,
Interventions that decrease mean glucose have reduced rates of micro- and macrovascular complications in type 1 diabetes (T1D). However, the difference in cardiovascular risk between people with T1D and the general population endures, suggesting that factors beyond hemoglobin A1C (HbA1c) normalization drive cardiovascular outcomes.
PRL-R Variants Are Not Only Associated With Prolactinomas But Also With Dopamine Agonist Resistance
Andrea Ramos de Castro Moreira, Ericka Trarbach, Cristina Bellotti Formiga Bueno, Anna Louise Stellfeld Monteiro, Isabella Pacetti Pajaro Grande, Mario Padula, Gustavo Arantes Rosa Maciel, Andrea Glezer
doi : 10.1210/clinem/dgad020
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e450–e457
Knockout prolactin receptor gene (PRL-R) mice are animal models for prolactinomas and PRL acts via autocrine/paracrine inhibiting lactotroph proliferation. Recently, variants of the PRL-R were identified in prolactinoma patients and their frequency was higher compared to individuals from the genomic database.
Identifying and Predicting Diverse Patterns of Benign Nodule Growth
PingPing Xiang, Sara Ahmadi, Alexandra Coleman, William West, Isabel Lobon, Athanasios Bikas, Iñigo Landa, Ellen Marqusee, Matthew Kim, Erik K Alexander, Theodora Pappa
doi : 10.1210/clinem/dgad007
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e458–e463
The natural history of benign thyroid nodules is typically characterized by slow growth and minimal risk of malignant transformation. Available data have, to date, been unable to elucidate the diversity of benign nodule growth patterns over time nor predictive of which patients follow which pattern.
Preconception Thyrotropin Levels and Thyroid Function at Early Gestation in Women With Hashimoto Thyroiditis
Mariacarla Moleti, Angela Alibrandi, Maria Di Mauro, Giuseppe Paola, Laura Giovanna Perdichizzi, Roberta Granese, Annamaria Giacobbe, Angela Scilipoti, Marta Ragonese, Alfredo Ercoli, Salvatore Benvenga, Francesco Vermiglio
doi : 10.1210/clinem/dgac748
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e464–e473
Preconception optimization of thyroid function in women with Hashimoto thyroiditis (HT) is highly recommended to prevent/reduce the risk of thyroid insufficiency at early gestation.
Prevaccination Glucose Time in Range Correlates With Antibody Response to SARS-CoV-2 Vaccine in Type 1 Diabetes
Ghadeer Alhamar, Silvia Briganti, Daria Maggi, Viola Viola, Malak Faraj, Carla Zannella, Massimiliano Galdiero, Gianluigi Franci, Clorinda Fusco, Camilla Isgrò, Giulia Leanza, Ilaria Malandrucco, Andrea Spinelli, Flavia Tramontana, Domenico Iaria, Rachele Tortoriello, Silvia Pieralice, Milena Rosati, Giuseppe Matarese, Paolo Pozzilli, Mario Galgani, Rocky Strollo
doi : 10.1210/clinem/dgad001
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e474–e479
Poor glucose control has been associated with increased mortality in COVID-19 patients with type 1 diabetes (T1D).
Elevated Serum Uric Acid Is Associated With Gestational Diabetes Mellitus: An Observational Cohort Study
Chaoyan Yue, Chunmei Ying, Xiaotian Li
doi : 10.1210/clinem/dgac760
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e480–e486
Elevated serum uric acid may be closely related to the occurrence of gestational diabetes mellitus (GDM).
Do Statins Blunt the Beneficial Effect of Aerobic Exercise on Metabolic Flexibility?
Tim Hollstein, Paolo Piaggi
doi : 10.1210/clinem/dgad049
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e487–e488
Aggressive Subtypes of Papillary Microcarcinoma
Ashok R Shaha
doi : 10.1210/clinem/dgad040
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e489–e490
Resistance Training: a Strong Case for People With Type 1 Diabetes?
Sarah E Siegelaar, Bastiaan E de Galan
doi : 10.1210/clinem/dgad037
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e491–e492
Liraglutide in Prader Willi–Syndrome: The Importance of Placebo-Controlled Studies
Carlos A Aguilar Salinas, Rita A Gómez DÃaz
doi : 10.1210/clinem/dgad017
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e493–e494
Growth Hormone Therapy in the Short SGA Child: Does Time Matter?
Christiaan de Bruin, Andrew Dauber
doi : 10.1210/clinem/dgad021
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e495–e496
Letter to the Editor From Zhang et al: “Effect of Inactivated and mRNA COVID-19 Vaccination on Thyroid Function Among Patients Treated for Hyperthyroidism�
Yang Zhang, Sainan Zhu, Ying Gao
doi : 10.1210/clinem/dgad094
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e497–e498
Response to Letter to the Editor From Zhang et al: “Effect of Inactivated and mRNA COVID-19 Vaccination on Thyroid Function Among Patients Treated for Hyperthyroidism�
Chun Ho Wong, Eunice Ka Hong Leung, Lawrence Chi Kin Tang, Chi Ho Lee, Carol Ho Yi Fong, Alan Chun Hong Lee, Yu Cho Woo, Kathryn Choon Beng Tan, David Tak Wai Lui
doi : 10.1210/clinem/dgad093
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Pages e499–e500
Withdrawn as duplicate: Expanding the phenotypic spectrum of Kenny-Caffey syndrome: a case series and systematic literature review
Heidi Schigt, Martin Bald, Bram C J van der Eerden, Lars Gal, Barnabas P Ilenwabor, Martin Konrad, Michael A Levine, Dong Li, Christoph J Mache, Sharon Mackin, Colin Perry, Francisco J Rios, Karl Peter Schlingmann, Ben Storey, Christine M Trapp, Annemieke J M H Verkerk, M Carola Zillikens, Rhian M Touyz, Ewout J Hoorn, Joost G J Hoenderop, Jeroen H F de Baaij
doi : 10.1210/clinem/dgad154
The Journal of Clinical Endocrinology & Metabolism, Volume 108, Issue 7, July 2023, Page e501
