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Predicting the Risk of Posttraumatic Osteoarthritis After Primary Anterior Cruciate Ligament Reconstruction: A Machine Learning Time-to-Event Analysis
Yining Lu,* MD , Anna K. Reinholz, * BS, Sara E. Till, * MS, Sydney V. Kalina, * BS, Daniel B.F. Saris, *y MD, PhD, Christopher L. Camp, * MD, and Michael J. Stuart, *z MD
doi : 10.1177/03635465231168139
There is a significant long-term risk of posttraumatic osteoarthritis (PTOA) after anterior cruciate ligament reconstruction (ACLR). Elucidating the risk factors and successfully identifying at-risk patients is challenging.
Radiographic Incidence of Knee Osteoarthritis After Isolated ACL Reconstruction Versus Combined ACL and ALL Reconstruction: A Prospective Matched Study From the SANTI Study Group
Jobe Shatrov, * MD, Benjamin Freychet, * MD, Graeme P. Hopper, *y MD , Benoit Coulin, * MD, Abdo El Helou, * MD, Jae-Sung An,* MD, Thais Dutra Vieira, *z MD , and Bertrand Sonnery-Cottet, * MD, PhD
doi : 10.1177/03635465231168899
Combined anterior cruciate ligament (ACL) reconstruction (ACLR) and anterolateral ligament reconstruction (ALLR) have demonstrated reduced risk of graft rerupture as compared with isolated ACLR. However, concerns remain that the risk of osteoarthritis (OA) may be increased by the addition of ALLR.
Association Between Anterior Tibial Subluxation of Lateral Compartment and High-Grade Knee Laxity in Patients With Anterior Cruciate Ligament Deficiency
Zipeng Ye, * MD , Xiulin Wu,* MD, Jiebo Chen, * MD , Eunshinae Cho, * MD , Guoming Xie, * MD, Shikui Dong, * MD, Junjie Xu, *y MD , and Jinzhong Zhao, *y MD
doi : 10.1177/03635465231166712
High-grade knee laxity and excessive anterior tibial subluxation (ATS) are correlated with poor clinical outcomes in patients with anterior cruciate ligament (ACL) deficiency and share similar risk factors; however, the association between excessive ATS and high-grade knee laxity remains unclear.
Rates of Septic Arthritis After ACL Reconstruction: A Single-Center Analysis Highlighting Quadriceps Tendon Grafts
Emre Anil O¨ zbek,*yz MD , Sahil Dadoo,y BS, Audrey Chang, § BA, Lauren Simonian, § BS, Romano Sebastiani, § BS, Zachary Herman,y MD, Armin Runer,y|| MD, Kathleen M. Poploski,{ PT, DPT, Clair N. Smith,y MS, James J. Irrgang,y{ PT, PhD, and Volker Musahl,y MD
doi : 10.1177/03635465231165509
Although the infection rates for bone–patellar tendon–bone autograft (BTB), hamstring tendon autograft (HT), and allograft have been reported previously, there are limited data available for a large cohort of individuals undergoing anterior cruciate ligament (ACL) reconstruction (ACLR) using quadriceps tendon autograft (QT).
Vancomycin Concentrations in Synovial Fluid Do Not Reach Chondrotoxic Thresholds After Anterior Cruciate Ligament Reconstruction With Vancomycin-Soaked Autologous Soft Tissue Grafts: An In Vivo Prospective Observational Study in Humans
Thomas R. Pfeiffer, *y MD, Prof. , Arne Althoff,z Sophia Krombholz, § Max Dautert, § Jan-Hendrik Naendrup,z MD, Daniel Guenther,z MHBA, MD, Bertil Bouillon,y MD, Prof., and Mario Thevis, § Prof
doi : 10.1177/03635465231169040
Studies have revealed that vancomycin soaking of the anterior cruciate ligament (ACL) graft can drastically reduce the incidence of postoperative infections after ACL reconstruction. However, it remains unknown whether the chondrotoxic threshold of vancomycin in synovial fluid is exceeded during this process. Several studies investigated the chondrotoxic properties of vancomycin in in vitro experiments and described a concentration of 1000 µg/mL as the critical threshold.
An Adolescent Murine In Vivo Anterior Cruciate Ligament Overuse Injury Model
Benjamin E. Loflin,* MSc, Taeyong Ahn,* PhD, Kaitlyn A. Colglazier,y Mark M. Banaszak Holl,z PhD, James A. Ashton-Miller,§ PhD, Edward M. Wojtys,|| MD, and Stephen H. Schlecht,*y{# PhD
doi : 10.1177/03635465231165753
Overuse ligament and tendon injuries are prevalent among recreational and competitive adolescent athletes. In vitro studies of the ligament and tendon suggest that mechanical overuse musculoskeletal injuries begin with collagen triple-helix unraveling, leading to collagen laxity and matrix damage. However, there are little in vivo data concerning this mechanism or the physiomechanical response to collagen disruption, particularly regarding the anterior cruciate ligament (ACL).
Synovial Fluid Proteomics From Serial Aspirations of ACL-Injured Knees Identifies Candidate Biomarkers
Muhammad Farooq Rai,*yz PhD , Lei Cai,y PhD, Qiang Zhang, § PhD, R. Reid Townsend, § MD, PhD, and Robert H. Brophy, *y MD
doi : 10.1177/03635465231169526
Anterior cruciate ligament (ACL) tears often result in knee effusion and an increased risk for developing knee osteoarthritis (OA) in the long run. The molecular profile of these effusions could be informative regarding initial steps in the development of posttraumatic OA after an ACL tear.
Peroneus Longus Split Versus Semitendinosus Tendon Autograft Size: A Cross-sectional Study
Guido Wierer, *yz MD , Clemens Gwinner, § MD, and Sven Scheffler, || Prof., MD
doi : 10.1177/03635465231165297
The anterior half of the peroneus longus tendon (AHPLT) has been reported to be a suitable autograft for ligament reconstruction with low donor-site morbidity. However, clinical data on graft size are limited.
Axial Compressive Loading Attenuates Early Osteoarthritis by Reducing Subchondral Bone Remodeling
Jianqun Wu,* MD , Yonghao Pan,yz Yangyi Yu, * MD , Qihao Yang,yz MD, Qisong Liu,* PhD, Yang Liu,yz PhD , Jinhao Zhong,yz , Linhao Fu,yz Haotian Cai,yz Chao Liu,yz§ PhD, and Guangheng Li, * § MD, PhD
doi : 10.1177/03635465231164644
Mechanical loading and alendronate (ALN) can be used as noninvasive physical therapy methods for osteoarthritis (OA). However, the timing and efficacy for treatments are unknown.
In Vivo Length Changes Between the Attachments of the Medial Patellofemoral Complex Fibers in Knees With Anatomic Risk Factors for Patellar Instability
Miho J. Tanaka, *y MD, PhD, Karina Mirochnik,y BS, MS, F. Joseph Simeone,z MD, Eric M. Berkson,y MD , Job N. Doornberg, § MD, PhD, and Kartik Mangudi Varadarajan,y PhD
doi : 10.1177/03635465231165296
Medial patellofemoral complex (MPFC) reconstruction plays an important role in the surgical treatment of patellar instability. Anatomic reconstruction is critical in re-creating the native function of the ligament, which includes minimizing length changes that occur in early flexion. Anatomic risk factors for patellar instability such as trochlear dysplasia, patella alta, and increased tibial tuberosity to trochlear groove (TT-TG) distance have been shown to influence the function of the MPFC graft in cadaveric studies, but the native length change patterns of the MPFC fibers in knees with anatomic risk factors have not been described.
Lower Patellofemoral Joint Contact Force During Side-Step Cutting After Return-to-Sports Clearance Following Anterior Cruciate Ligament Reconstruction
Argell J. San Jose, *yz BSN, BSc, Nirav Maniar, *z PhD, Rodney Whiteley, §|| PT, PhD, David A. Opar, *z PhD, Ryan G. Timmins, *z{ PhD, and Roula Kotsifaki §# PhD
doi : 10.1177/03635465231166104
Low patellofemoral joint (PFJ) contact force has been associated with PFJ osteoarthritis. Quadriceps force and knee flexion angles, which are typically altered after an anterior cruciate ligament reconstruction (ACLR), primarily influence PFJ contact forces. It is still inconclusive whether differences in PFJ contact forces are present during high knee flexion tasks such as side-step cutting after clearance to return to sports (RTS) after ACLR.
Normative Values of Tibial Tubercle–Trochlear Groove Distance and Tibial Tubercle–Posterior Cruciate Ligament Distance in Children
Se Jin Park, * MD, Seung Hyun Won,y PhD, Moon Seok Park,z MD, and Ki Hyuk Sung,z§ MD
doi : 10.1177/03635465231165521
Patellar instability is a common knee pathology in skeletally immature patients. In skeletally mature populations, a tibial tubercle–trochlear groove (TT-TG) distance of ≥20 mm is generally considered a pathological value. However, as pediatric patients grow and as the TT-TG distance varies with age, applying the same cutoff value as adult patients to them is unreasonable.
Localization of the Adductor Tubercle in the Skeletally Immature: A Computed Tomography Study With Patellofemoral Surgical Implications
Sahir S. Jabbouri, * MD , William McLaughlin, * MD , Peter Joo,* MD, Daniel Cooperman, * MD, John P. Fulkerson, * MD, and David B. Frumberg, *y MD
doi : 10.1177/03635465231166027
The adductor tubercle of the distal femur is utilized by surgeons as an anatomic landmark to identify graft anchor placement during medial patellofemoral ligament (MPFL) and medial quadriceps tendon femoral ligament (MQTFL) reconstruction for patellofemoral instability. In the skeletally immature population, its location relative to the physis has not been well defined.
Return to Sport in Middle-aged and Older Athletes After Unicompartmental Knee Arthroplasty at a Mean 10-Year Follow-up: Radiographic and Clinical Outcomes
Kevin D. Plancher, *yz§|| MD, MPH, Clifford Voigt, §|| MD, David N. Bernstein,{ MD, MBA, MEI, Karen K. Briggs, || MPH, and Stephanie C. Petterson, || MPT, PhD
doi : 10.1177/03635465231163859
Return to sport is essential information when an athlete contemplates surgical intervention. Young athletes, <30 years of age, may undergo complex cartilage procedures or femoral/tibial osteotomies to successfully treat single-compartment knee osteoarthritis. Unicompartmental knee arthroplasty (UKA) may offer an attractive alternative option to middle-aged/older athletes with timely return to the same sport without a lengthy rehabilitation.
Does the dGEMRIC Index Recover 3 Years After Surgical FAI Correction and an Initial dGEMRIC Decrease at 1-Year Follow-up? A Controlled Prospective Study
Malin Kristin Meier,*y MD, Samira Scheuber,y MD, Markus Simon Hanke,y MD, Pascal Cyrill Haefeli,z MD, Adrian Cyrill Ruckli, § MA, Emanuel Francis Liechti,y MD, Nicolas Gerber, § PhD , Till Dominic Lerch,|| MD, PhD , Moritz Tannast,{ MD, Klaus Arno Siebenrock,y MD, Simon Damian Steppacher,y MD, and Florian Schmaranzer, || MD, PhD
doi : 10.1177/03635465231167854
Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) allows objective and noninvasive assessment of cartilage quality. An interim analysis 1 year after correction of femoroacetabular impingement (FAI) previously showed that the dGEMRIC index decreased despite good clinical outcome.
Results of Endoscopic Labral Repair With Concomitant Gluteus Medius and/or Minimus Repair Compared With Outcomes of Labral Repair Alone: A Matched Comparative Cohort Analysis at Minimum 2-Year Follow-up
Nolan S. Horner, * MD, Reagan S. Chapman, * MD, Jordan H. Larson, * BS, and Shane J. Nho, *y MD, MS
doi : 10.1177/03635465231166708
There is a paucity of information available to clinicians on outcomes of patients undergoing endoscopic surgery for labral repairs and femoroacetabular impingement syndrome with simultaneous repair of the gluteus medius and/or minimus muscles.
MRI Does Not Improve Inter- or Intrarater Reliability for Hip Arthritis Grading Systems
. Michael Pullen, *y MD, Kinsley Pierre,z BS, Ivan Wong, § MD, Stephen K. Aoki, || MD, T. Sean Lynch,{ MD, Richard C. Mather III, # MD, MBA, Olufemi R. Ayeni, ** MD, PhD, J.W. Thomas Byrd,yy MD, and Marc R. Safran,zz MD
doi : 10.1177/03635465231167866
Magnetic resonance imaging (MRI) scans and radiographs are often utilized in assessing for preoperative osteoarthritis in patients undergoing hip preservation surgery.
Irreversible Electroporation Improves Tendon Healing in a Rat Model of Collagenase-Induced Achilles Tendinopathy
Xin Wang, *y MD, PhD, Kui Xu,* MD, PhD, Eryang Zhang,z MS, Qian Bai,§ MD, Baoan Ma, * MD, PhD, ChenGuang Zhao, || MD, Kailiang Zhang,{ MD, Tao Liu,* MD, PhD, Zhouyong Ma,z Hui Zeng,z MS, Yong Zhou,* # MD, PhD, and Zhao Li,z# MD, PhD
doi : 10.1177/03635465231167860
Treatment of painful chronic tendinopathy is challenging, and there is an urgent need to develop new regenerative methods. Irreversible electroporation (IRE) can lead to localized cell ablation by electrical pulses and induce new cell and tissue growth. Previously, the authors’ group reported that electroporation-ablated tendons fully regenerated.
Midterm Outcomes Following Combined Biceps Tenodesis and Anterior Labral Repair in Active Duty Military Patients Younger Than 35 Years
Clare K. Green,*y BS, John P. Scanaliato,z§ MD, Alexis B. Sandler,z§ MD , Hunter Czajkowski, ||{ BS, Robert H. Rolf,# ** MD, John C. Dunn,z§ MD, and Nata Parnes, ||{ MD
doi : 10.1177/03635465231169238
Superior labrum anterior-posterior (SLAP) lesions and anterior instability are common causes of shoulder pain and dysfunction among active-duty members of the United States military. However, little data have been published regarding the surgical management of type V SLAP lesions.
Resolution of Sleep Disturbance and Improved Functional Outcomes After Rotator Cuff Repair
Evan T. Zheng, * MD, Natalie A. Lowenstein, * BS, Jamie E. Collins, * PhD, and Elizabeth G. Matzkin, *y MD
doi : 10.1177/03635465231169254
Most patients experience sleep disturbances before rotator cuff repair, with these symptoms largely improving postoperatively. However, the relationship between the resolution or persistence of sleep disturbance and patient-reported outcomes after rotator cuff repair remains unknown.
Optimal Blood Flow Restriction Occlusion Pressure for Shoulder Muscle Recruitment With Upper Extremity Exercise
Tyler Roehl, * PT, DPT, ATC, Bradley S. Lambert, * PhD, Jordan Ankersen, * BS, Karen Hernandez, * BS, Patrick C. McCulloch, * MD, and Corbin Hedt, *y PT, DPT
doi : 10.1177/03635465231166959
As blood flow restriction (BFR) utilization continues to rise, it is crucial to define optimal parameters for use. Currently unknown are the effects of occlusion level during BFR on muscle activity in the proximal shoulder.
Menstrual Blood–Derived Mesenchymal Stem Cells Encapsulated in Autologous Platelet-Rich Gel Facilitate Rotator Cuff Healing in a Rabbit Model of Chronic Tears
Ya Song, *y MMed, Ping Li,yz MD, Yan Xu, * MMed, Zhangyuan Lin, *y§ MD, Zhenhan Deng, §k MD, PhD , and Can Chen, * §k MD, PhD
doi : 10.1177/03635465231168104
Successful management of chronic rotator cuff (RC) tears remains a challenge owing to its limited intrinsic healing capacity and unsatisfactory failure rate. Menstrual blood–derived mesenchymal stem cells (MenSCs) have the potential to differentiate into the chondrogenic or osteogenic lineage. Autologous platelet-rich gel (APG), a gel material derived from platelet-rich plasma (PRP), can be applied as a carrier system for cell delivery and also as a releasing system for endogenous growth factors.
Effect of Repetitive Corticosteroid Injection on Tennis Elbow Surgery
Cheungsoo Ha, * MD, Weonmin Cho, * MD, In-Tae Hong,y MD, PhD, Junhyoung Park,z Wooyeol Ahn,* MD, and Soo-Hong Han,* § MD, PhD
doi : 10.1177/03635465231166397
Lateral epicondylitis is a chronic tendinopathy of humeral origin of the common extensor tendon. Most patients show improvement after nonoperative treatment. However, 4% to 11% of patients require surgical treatment. Although corticosteroid injection is one of the most commonly applied nonoperative treatment methods, to the authors’ knowledge, no study has reported the effect of the number of preoperative corticosteroid injections on the final postoperative outcome.
Biomechanical Comparison of Distal Biceps Tendon Repair Techniques: Extracortical Single-Button Inlay Fixation Versus Intracortical Double-Button Onlay Anatomic Footprint Fixation
Lukas Ernstbrunner, *yz§ MD, PhD, Mitchell Almond,z MS, Harshi S. Rupasinghe,z MS, Olivia I. Jo, § MD, Robert M. Zbeda, * MD, David C. Ackland,z PhD, and Eugene T. Ek, *y||{ MBBS, PhD
doi : 10.1177/03635465231171131
Extracortical single-button (SB) inlay repair is a commonly used distal biceps tendon technique. However, complications (eg, neurovascular injury) and nonanatomic repairs have led to the development of intracortical fixation techniques.
A Systematic Review of Long-term Clinical and Radiological Outcomes of Arthroscopic and Open/Mini-open Rotator Cuff Repairs
Fabian Plachel, * MD, PhD, Olivia Imkyeong Jo,y MD, Katja Ru¨ ttershoff, * Octavian Andronic,z MD, and Lukas Ernstbrunner,y§||{ MD, PhD
doi : 10.1177/03635465211073332
Arthroscopic rotator cuff repair (aRCR) has shown similar midterm functional results and retear rates as open/mini-open rotator cuff repair (oRCR). A pooled analysis of long-term results of both techniques is yet missing.
Examining the Efficacy of Medial Meniscus Posterior Root Repair: A Meta-analysis and Systematic Review of Biomechanical and Clinical Outcomes
Allison K. Perry, * BS, Ophelie Lavoie-Gagne,y MD , Derrick M. Knapik, * MD, Bhargavi Maheshwer,z MD, Alexander Hodakowski, * MS, Safa Gursoy, * MD, PhD, Robert F. LaPrade, § MD, PhD, and Jorge Chahla, * || MD, PhD
doi : 10.1177/03635465221077271
Medial meniscus posterior root (MMPR) injuries accelerate the progression of osteoarthritis. While partial meniscectomy was once considered the gold standard for treatment, meniscus root repair has become increasingly utilized with reported improvements in clinical and biomechanical outcomes.
Evidence-Based Hamstring Injury Prevention and Risk Factor Management: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Samuel S. Rudisill, *yz BS, Nathan H. Varady,y§ MD, MBA, Michael P. Kucharik,y BS, Christopher T. Eberlin,y BS, and Scott D. Martin,y MD
doi : 10.1177/03635465221083998
Hamstring injuries are common among athletes. Considering the potentially prolonged recovery and high rate of recurrence, effective methods of prevention and risk factor management are of great interest to athletes, trainers, coaches, and therapists, with substantial competitive and financial implications.
One in Three Patients With Chronic Lateral Ankle Instability Has a Cartilage Lesion
Emma J. Wijnhoud, *yz BSc, Quinten G.H. Rikken, *yz BSc , Jari Dahmen, *yz MD, BSc, Inger N. Sierevelt, §|| MSc, Sjoerd A.S. Stufkens, *yz MD, PhD, and Gino M.M.J. Kerkhoffs, *yz{ MD, PhD
doi : 10.1177/03635465221084365
Chronic lateral ankle instability (CLAI) is associated with the presence or development of intra-articular pathologies such as chondral or osteochondral lesions, or (O)CLs. Currently, the incidence of (O)CLs in patients with CLAI is unknown.
In Memoriam: J. Richard Steadman, MD (1937-2023): A Pioneer in Sports Medicine Innovation and a Champion for His Patients
Marc J. Philippon, MD
Intraoperative Channeling in Arthroscopic Rotator Cuff Repair: Letter to the Editor
Sichun Zhao Gang Liu Dingwei Zhang Shitian Tang
Intraoperative Channeling in Arthroscopic Rotator Cuff Repair: Response
Peter Lapner, MD, FRCSC J. Whitcomb Pollock, MD, MSc, FRCSC Ottawa, Ontario, Canada Martin Bouliane, MD, FRCSC
