Circulation




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Rheumatic Heart Disease Research Collaborative in Uganda.

Okello, Emmy MBChB, MMed, PhD; Beaton, Andrea MD

doi : 10.1161/CIRCULATIONAHA.123.063748

Volume 147(24) pgs. 1785-1868,e721-e721 June 13, 2023

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Effects of Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide: A Secondary Analysis of the Randomized LOOP Study.

Xing, Lucas Yixi MD ,,*; Diederichsen, Soren Zoga MD, PhD ,,*; Hojberg, Soren MD, PhD; Krieger, Derk W. MD, PhD; Graff, Claus MSc, PhD; Frikke-Schmidt, Ruth MD, DMSc; Olesen, Morten S. MSc, PhD; Brandes, Axel MD, DMSc; Kober, Lars MD, DMSc; Haugan, Ketil Jorgen MD, PhD; Svendsen, Jesper Hastrup MD, DMSc

doi : 10.1161/CIRCULATIONAHA.123.064361

Research suggests NT-proBNP (N-terminal pro-B-type natriuretic peptide) to be a strong predictor of incident atrial fibrillation (AF) and stroke. However, its utility in AF screening remains unknown.

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Sex Differences in Cardiac Troponin Trajectories Over the Life Course.

de Bakker, Marie MSc; Anand, Atul MD, PhD; Shipley, Martin MSc; Fujisawa, Takeshi PhD; Shah, Anoop S.V. MD, PhD; Kardys, Isabella MD, PhD; Boersma, Eric PhD; Brunner, Eric J. PhD; Mills, Nicholas L. MD, PhD; Kimenai, Dorien M. PhD

doi : 10.1161/CIRCULATIONAHA.123.064386

Cardiac troponin concentrations are lower in women than men. We examined whether age- and risk factor-related changes in cardiac troponin over the life course differ by sex and if the trajectory of cardiac troponin was informative in respect of cardiovascular outcomes in women and men in the general population.

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Serum and Pulmonary Expression Profiles of the Activin Signaling System in Pulmonary Arterial Hypertension.

Guignabert, Christophe PhD; Savale, Laurent MD, PhD; Boucly, Athenais MD, PhD; Thuillet, Raphael BSc; Tu, Ly PhD; Ottaviani, Mina BSc; Rhodes, Christopher J. PhD; De Groote, Pascal MD; Prevot, Gregoire MD; Bergot, Emmanuel MD, PhD; Bourdin, Arnaud MD, PhD; Howard, Luke S. MD; Fadel, Elie MD, PhD; Beurnier, Antoine MD; Roche, Anne MD; Jevnikar, Mitja MD; Jais, Xavier MD; Montani, David MD, PhD; Wilkins, Martin R. MD, DSc; Sitbon, Olivier MD, PhD; Humbert, Marc MD, PhD

doi : 10.1161/CIRCULATIONAHA.122.061501

Activins are novel therapeutic targets in pulmonary arterial hypertension (PAH). We therefore studied whether key members of the activin pathway could be used as PAH biomarkers.

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Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.

Cho, Kyu-Won PhD; Andrade, Mark BS; Bae, Seongho PhD; Kim, Sangsung MS; Eyun Kim, Jin MS; Jang, Er Yearn BS; Lee, Sangho PhD; Husain, Ahsan PhD; Sutliff, Roy L. PhD; Calvert, John W. PhD; Park, Changwon PhD; Yoon, Young-sup MD, PhD

doi : 10.1161/CIRCULATIONAHA.122.061131

Shortly after birth, cardiomyocytes exit the cell cycle and cease proliferation. At present, the regulatory mechanisms for this loss of proliferative capacity are poorly understood. CBX7 (chromobox 7), a polycomb group (PcG) protein, regulates the cell cycle, but its role in cardiomyocyte proliferation is unknown.

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Absorbing Account of Premature Myocardial Infarction.

Ajufo, Ezimamaka BM BCh; Channaoui, Nadine MS, CGC; Marston, Nicholas MD, MPH

doi : 10.1161/CIRCULATIONAHA.123.064466

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Refining Risk Stratification Among Children With Latent Rheumatic Heart Disease.

Beaton, Andrea MD ,,*; Okello, Emmy PhD ,,*; Rwebembera, Joselyn MMed; Grobler, Anneke PhD; Engelman, Daniel PhD; Alepere, Juliet BA; Carapetis, Jonathan PhD; DeWyer, Alyssa MD; Lwabi, Peter MMed; Mirabel, Mariana PhD; Mocumbi, Ana Olga PhD; Nakitto, Miriam MPH; Ndagire, Emma MMed; Nunes, Maria Carmo P. PhD; Omara, Isaac Otim BNS; Sarnacki, Rachel BA; Scheel, Amy MD; Wilson, Nigel PhD; Zuhlke, Liesl PhD; Karthikeyan, Ganesan MD; Sable, Craig A. MD; Steer, Andrew C. PhD

doi : 10.1161/CIRCULATIONAHA.122.063194

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Letter by Zhu et al Regarding Article, "Temperature Control After In-Hospital Cardiac Arrest: A Randomized Clinical Trial".

Zhu, Jianbing MD; Zheng, Zeqi MD; Peng, Xiaoping MD

doi : 10.1161/CIRCULATIONAHA.122.063485

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Response by Roedl et al to Letter Regarding Article, "Temperature Control After In-Hospital Cardiac Arrest: A Randomized Clinical Trial".

Roedl, Kevin MD; Wolfrum, Sebastian MD; Kluge, Stefan MD

doi : 10.1161/CIRCULATIONAHA.123.064051

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KIDS SAVE LIVES: Basic Life Support Education for Schoolchildren: A Narrative Review and Scientific Statement From the International Liaison Committee on Resuscitation.

Schroeder, Daniel C. MD; Semeraro, Federico MD, Vice Chair; Greif, Robert MD, MME; Bray, Janet RN, PhD, FAHA; Morley, Peter MBBS, FAHA; Parr, Michael MBBS; Kondo Nakagawa, Naomi PT, MSc, PhD, FAHA; Iwami, Taku MD, PhD; Finke, Simon-Richard MD; Malta Hansen, Carolina MD, PhD; Lockey, Andrew MB, ChB, PhD; Del Rios, Marina MD, MSc; Bhanji, Farhan MD, MSc (Ed); Sasson, Comilla MD, PhD, FAHA; Schexnayder, Stephen M. MD; Scquizzato, Tommaso; Wetsch, Wolfgang A. MD; Bottiger, Bernd W. MD, FAHA, Chair; on behalf of the International Liaison Committee on Resuscitation

doi : 10.1161/CIR.0000000000001128

Basic life support education for schoolchildren has become a key initiative to increase bystander cardiopulmonary resuscitation rates. Our objective was to review the existing literature on teaching schoolchildren basic life support to identify the best practices to provide basic life support training in schoolchildren.

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Correction to: 2023 EPI/Lifestyle Abstract 17.

doi : 10.1161/CIR.0000000000001159

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