Journal of Herbal Medicine




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Editorial

Kofi Busia

doi : 10.1016/j.hermed.2023.100660

Volume 39, June 2023, 100660

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Effect of miswak chewing sticks on Oral Helicobacter Pylori under both fasting and non-fasting conditions – A preliminary cross-over randomized clinical trial

Jagan Kumar Baskaradoss a,*, Eman Behbehani a, Maribasappa Karched

doi : 10.1016/j.hermed.2023.100646

Volume 39, June 2023, 100646

The chewing stick or “miswak� has demonstrated growth-inhibitory effects on several oral micro-organisms including Helicobacter pylori (H. pylori). This study explores the effect of miswak on oral H. pylori among fasting and non-fasting subjects.

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Ethnobotanical study of medicinal plants used to treat HIV, cancer and diabetes in some communities of Ashanti Region, Ghana

Caleb Kesse Firempong a,*, Patrick Addo-Fordjour b, Gustav Komlaga c, Yaw Ameyaw d, Nwoke Okechi Nirvana b, Kumi Frederick b, Asare-Amankwah Yaw

doi : 10.1016/j.hermed.2023.100648

Volume 39, June 2023, 100648

Medicinal plants play important roles in primary healthcare in Ghana, where many are used to treat chronic diseases including HIV, diabetes mellitus, and cancer. However, there is little or no documentation on the medicinal uses of many of these plants.

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Anacyclus pyrethrum extract significantly destroyed lung cancer cell line (A549) by inducing apoptosis

Ali Mohammadi a,b, Behzad Mansoori a,c, Elham Safarzadeh a, Sahar Gholizadeh a, Behzad Baradaran

doi : 10.1016/j.hermed.2023.100649

Volume 39, June 2023, 100649

Lung cancer is one of the serious human health problems and many researchers have focused on identifying new therapeutic agents and effective therapies. Recently, herbal medicines have been used for the treatment of various diseases such as cancer. This research aimed to investigate the potential anti-tumoral activity and clarify the respective mechanisms of Anacyclus pyrethrum plant extract on the A549 lung cancer cell line.

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The use of herbal and dietary supplements for COVID-19 prevention: A survey among the public in a Malaysian suburban town

Mohd Shahezwan Abd Wahab a,b,*, Humaira’ Hamdi a, Aida Azlina Ali a, Mahmathi Karuppannan a, Muhammad Harith Zulkifli a, Sandra Maniam c, Carolina Oi Lam Ung

doi : 10.1016/j.hermed.2023.100650

Volume 39, June 2023, 100650

The spread of the novel coronavirus disease (COVID-19) may lead people to seek preventative measures. The use of herbal and dietary supplements (HDS) may have become prevalent during the COVID-19 pandemic. This study aims to identify the prevalence, predictors, and patterns of HDS use for COVID-19 prevention in a sample of the general public in a suburban town in Malaysia.

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Essential oil of Origanum minutiflorum exhibits anti-inflammatory and antioxidative effects in human bronchial cells and antimicrobial activity on lung pathogens

Katarina Veljovic a, Vele Tesevic b, Hristina Mitrovic c, Marija Stankovic

doi : 10.1016/j.hermed.2023.100651

Volume 39, June 2023, 100651

Oregano essential oil (OEO) is one of the most widely used essential oils worldwide due to its huge therapeutic benefits. Nevertheless, data on the effects of the endemic species Origanum minutiflorum, also known as wild or Turkish oregano, is scarce.

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Scoparia dulcis and Indigofera tinctoria as potential herbal remedies against 7-ketocholesterol-induced pro-inflammatory mediators of macrophage polarization

Parimalanandhini Duraisamy a, Sangeetha Ravi a, Mahalakshmi Krishnan a, Livya Catherene Martin a, Beulaja Manikandan b, Thiagarajan Raman c, Arumugam Munusamy a, Manikandan Ramar

doi : 10.1016/j.hermed.2023.100652

Volume 39, June 2023, 100652

Herbs with medicinal properties contribute to atheroprotective effects through their preventive and therapeutic interactions with macrophages. Scoparia dulcis and Indigofera tinctoria are examples of such medicinal owing to their antiinflammatory, antioxidant, antibacterial and anticancer properties. The aim of this study was to investigate the antiatherogenic potential of hot- and cold-water extracts of Scoparia dulcis (HwSd and CwSd) and Indigofera tinctoria (HwIt and CwIt).

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The regulatory effects of Lonicera japonica flos on fecal microbiota from humans with type 2 diabetes in a SHIME model

Lan Yang a,b,c, Jiali Zhou a,b, Yushuang Luo a,b, Xincong Kang a,b, Xihu Lai b, Zhe Zhou a,b, Xiaohong Zhong a,*, Dongbo Liu

doi : 10.1016/j.hermed.2023.100654

Volume 39, June 2023, 100654

Lonicera japonica flos, a well-known herbal medicine in Asian countries, has been widely used for the treatment of type 2 diabetes (T2D). The gut microbiota and relevant metabolites have been shown to be involved in the development of T2D. This study was designed to investigate the effects of Lonicera japonica flos on fecal microbiota from humans with T2D using the Simulator of the Human Intestinal Microbial Ecosystem (SHIME) system.

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Systematic exploration of the efficacy marker compounds of Danshen (Salvia miltiorrhiza Bge.) driven by the efficacy network target

Bo Li a,b, Yan-hong Wu a, Cui-bai Li a, Xiang Yang a, Bu-jin Ma a, Can Zhao a, Zhu-yun Yan

doi : 10.1016/j.hermed.2023.100656

Volume 39, June 2023, 100656

Chinese Materia Medica (CMM) provides medical treatment and healthcare worldwide. However, precision quality control of CMM is considered a bottleneck in Chinese herbal modernization. Considering the multi-efficacy of the clinical applications of CMM, we adopted a novel strategy based on the efficacy network target to screen for efficacy-related constituents and efficacy markers.

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Therapeutic effect of Achillea millefolium on the hemorrhoids; A randomized double-blind placebo-controlled clinical trial

Aynaz Mahmoudi a,1, Mirsalim Seyedsadeghi b,1, Mansour Miran a, Saeid Sadeghieh Ahari b, Hojat Layegh b, Sara Mostafalou

doi : 10.1016/j.hermed.2023.100657

Volume 39, June 2023, 100657

Hemorrhoids are prevalent diseases affecting health and well-being, and treatments are generally symptomatic. Achillea millefolium (Yarrow) has long been used to treat inflammatory and infectious diseases. The present work was performed to assess the effect of hydroalcoholic extract of A. millefolium as an ointment on the symptoms of hemorrhoids.

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Antimicrobial, antifungal and antiradical activities of the essential oils from the flower and leaf extracts of Iranian Ferulago macrocarpa plant

Farideh Azarbani a, Faranak Hadi a,*, Samira Jafari a, H.C. Ananda Murthy b,c, Abul Kalam Azad

doi : 10.1016/j.hermed.2023.100658

Volume 39, June 2023, 100658

The essential oils (EOs) extracted from the flowers and leaves of Ferulago macrocarpa (Fenzl) Boiss (F. macrocarpa) plant were traditionally used to treat bacterial and fungal infections in the people of Lorestan Province, Iran for several centuries. The present study aims to analyse the EOs of flower and leaf extracts of F. macrocarpa using Gas Chromatography/Mass-spectrometry (GC-MS) technique and investigate their antibacterial, antifungal and antiradical activities.

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Chromatographic (LC-MS and GC-MS) and biological (antiproliferative) evaluation of a naturalized plant in Jordan: Parkinsonia aculeata L.

Oriana Awwad a, Nour Aboalhaija b, Ismail Abaza c, Reem Abbassi a, Mohammad H. Kailani d, Hala Al-Jaber e, Fatma U. Afifi

doi : 10.1016/j.hermed.2023.100659

Volume 39, June 2023, 100659

Parkinsonia aculeata L. (Caesalpiniaceae), native to the Sonoran and Chihuahuan deserts of southwestern USA and northern Mexico, has been introduced and successfully propagated in Jordan within the Greening the Desert Project. No phytochemical or biological studies have been carried out with this species grown in Jordan.

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Three decades of research on Centella asiatica: Insights and future trends from bibliometric analysis

AB Oyenihi a,*,1, TT George b, OR Oyenihi c, AO Obilana b, M. Opperman

doi : 10.1016/j.hermed.2023.100662

Volume 39, June 2023, 100662

Centella asiatica (L.) Urb. (CA; Family: Apiaceae) remains a major herb in the indigenous medicines of many Asian and African countries. Scientists have been delving deeper to fully understand the rationale for the various anecdotal therapeutic claims ascribed to its usage. Here, we present a comprehensive analysis of the published research on CA within the past three decades.

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The anticancer effect of Salvia pisidica essential oil through promotion intrinsic and extrinsic apoptosis pathways in human cancer cell lines

Gürkan Semiz a,1, Do?gukan Mutlu a,2, Bat?kan Günal a,3, Asl? Semiz b,4, S¸ evki Arslan

doi : 10.1016/j.hermed.2023.100664

Volume 39, June 2023, 100664

Species of the Salvia genus are aromatic herbs and traditionally used for many medicinal purposes in Anatolia. The genus has produced an extraordinarily large number of beneficial secondary metabolites belonging to numerous chemical groups. Salvia pisidica is an endemic plant of southwest Anatolia, the dried parts of which are used as herbal tea and local materia medica.

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Analytical review of Tiry�q-i-Wab�ī – A Unani panacea for the control of COVID-19

Noman Anwar a,*, N. Zaheer Ahmed a, A. Farhath Fathima b, Asim Ali Khan

doi : 10.1016/j.hermed.2023.100653

Volume 39, June 2023, 100653

COVID-19 has affected the whole world drastically and led to a substantial loss of human life. Relentless research is underway to identify effective treatment to control the disease. Traditional systems are also being explored to search for a potent drug. Unani formulation ‘Tiry�q-i-Wab�ī’ has long been used in cholera, plague and other epidemic diseases. This review is aimed at analysing the possible role of Tiry�q-i-Wab�ī in the prevention and control of COVID-19.

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Effects of cinnamon supplementation on serum levels of liver enzymes: A systematic review and meta-analysis of randomized controlled clinical trials

Zeinab Yazdanpanah a,b,1, Sara Beigrezaei a,b,1, Sahar Mohseni-Takalloo a,b,d, Amin Salehi-Abargouei a,b

doi : 10.1016/j.hermed.2023.100655

Volume 39, June 2023, 100655

A systematic review and meta-analysis of the effect of cinnamon supplementation on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and total bilirubin.

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How effective are essential oils and essential oil constituents in the management of intra-oral halitosis: A systematic review

Marie Dubar a,1, Anne-Charlotte Decock a,1, Jerome Petit a, Elisabeth Delcourt-Debruyne a,b, Alessandra Blaizot c, Kevimy Agossa

doi : 10.1016/j.hermed.2023.100663

Volume 39, June 2023, 100663

To systematically review evidence regarding the efficacy of EOs and their constituents in the treatment of halitosis.

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Traditional uses, ethnopharmacology, antibacterial and antiparasitic activities of Symphonia spp

Ben Lukubye a,*, Rapheal Wangalwa a,b, Grace Kagoro-Rugunda

doi : 10.1016/j.hermed.2023.100666

Volume 39, June 2023, 100666

Genus Symphonia has evident medicinal importance reported in different literature but with no contextualized review of the ethnopharmacology, antibacterial and antiparasitic activity. This study reviewed and contextualized the ethnomedical uses, antibacterial and antiparasitic activities of medicinal Symphonia species.

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Corrigendum to “Documentation of traditional medicinal plants use in Ensaro District, Ethiopia: Implications for plant biodiversity and indigenous knowledge conservation� [J. Herb. Med. 38 (100641) (2023)]

Asaye Asfaw a,b,*, Ermias Lulekal b, Tamrat Bekele b, Asfaw Debella c, Hiwot Moges c, Samuel Tessema c, Asfaw Meresa c, Abiy Abebe c, Sileshi Degu c, Eyob Debebe

doi : 10.1016/j.hermed.2023.100661

Volume 39, June 2023, 100661

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