European Heart Journal




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Thrombotic and bleeding complications during antithrombotic treatment: the need for new therapeutic targets

Filippo Crea

doi : 10.1093/eurheartj/ehad285

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1767–1770

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New director opens a fresh chapter in the history of a leading US heart centre

Judith Ozkan

doi : 10.1093/eurheartj/ehad138

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1771–1772

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A memory for Claudio Rapezzi

Roberto Ferrari

doi : 10.1093/eurheartj/ehac773

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1773–1774

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The physician and the monk

Ankur Kalra

doi : 10.1093/eurheartj/ehad037

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1775–1777

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Higher hospital readmissions in blacks after acute myocardial infarction: healthcare inequality gaps to fill in secondary prevention

Daniela Pedicino, Massimo Volpe

doi : 10.1093/eurheartj/ehad179

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1778–1779

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Reversal and removal of oral antithrombotic drugs in patients with active or perceived imminent bleeding

Davide Cao, Nicolas Amabile, Mauro Chiarito, Victoria T Lee, Dominick J Angiolillo, Davide Capodanno, Deepak L Bhatt, Michael J Mack, Robert F Storey, Michael Schmoeckel, C Michael Gibson, Efthymios N Deliargyris, Roxana Mehran

doi : 10.1093/eurheartj/ehad119

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1780–1794

Remarkable progress has been made in the pharmacological management of patients with cardiovascular disease, including the frequent use of antithrombotic agents. Nonetheless, bleeding complications remain frequent and potentially life-threatening.

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Reversal agents for current and forthcoming direct oral anticoagulants

Nick van Es, Raffaele De Caterina, Jeffrey I Weitz

doi : 10.1093/eurheartj/ehad123

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1795–1806

Over the past 20 years, there has been a shift from vitamin K antagonists to direct oral anticoagulants (DOACs), which include the thrombin inhibitor dabigatran and the factor Xa inhibitors apixaban, edoxaban, and rivaroxaban.

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Outcomes of patients with atrial fibrillation and ischemic stroke while on oral anticoagulation

Alexander P Benz, Stefan H Hohnloser, John W Eikelboom, Anthony P Carnicelli, Robert P Giugliano, Christopher B Granger, Josephine Harrington, Ziad Hijazi, David A Morrow, Manesh R Patel, David J Seiffge, Ashkan Shoamanesh, Lars Wallentin, Qilong Yi, Stuart J Connolly

doi : 10.1093/eurheartj/ehad200

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1807–1814

The prognosis of patients with atrial fibrillation (AF) and ischemic stroke while taking oral anticoagulation is poorly understood. This study aimed to characterize the outcomes of patients following a stroke event while on oral anticoagulation.

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Ischaemic stroke in atrial fibrillation patients while on oral anticoagulation—a call for A-C-T-I-O-N

Haeusler Karl Georg

doi : 10.1093/eurheartj/ehad203

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1815–1817

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JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study

Luca Liberale, Yustina M Puspitasari, Stefano Ministrini, Alexander Akhmedov, Simon Kraler, Nicole R Bonetti, Georgia Beer, Ana Vukolic, Dario Bongiovanni, Jiaying Han, Kilian Kirmes, Isabell Bernlochner, Jaroslav Pelisek, Jürg H Beer, Zheng-Gen Jin, Daniela Pedicino, Giovanna Liuzzo, Konstantinos Stellos, Fabrizio Montecucco, Filippo Crea, Thomas F Lüscher, Giovanni G Camici

doi : 10.1093/eurheartj/ehac641

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1818–1833

Variants of the junctional cadherin 5 associated (JCAD) locus associate with acute coronary syndromes. JCAD promotes experimental atherosclerosis through the large tumor suppressor kinase 2 (LATS2)/Hippo pathway. This study investigates the role of JCAD in arterial thrombosis.

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JCAD: a new GWAS target to reduce residual cardiovascular risk?

Tomasz J Guzik, Keith M Channon

doi : 10.1093/eurheartj/ehac708

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1834–1836

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Thrombolytic treatment of life-threatening pulmonary embolism in times of alteplase shortage

Frederikus A Klok, Piotr Pruszczyk, Stavros V Konstantinides

doi : 10.1093/eurheartj/ehad120

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1837–1839

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Closure of patent foramen ovale after surgery with atrial septal defect occluder accompanied by Marfan syndrome

Zhang Cheng, Junzhou Pu, Wenhui Wu

doi : 10.1093/eurheartj/ehad159

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Page 1840

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Flow visualization of a unique case of persistent truncus arteriosus with prolonged survival

Yao Xie, Chengchen Zhao, Meixiang Xiang

doi : 10.1093/eurheartj/ehad183

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Page 1841

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Cardiac Richter’s syndrome: a rare case of chronic lymphocytic leukaemia transformation

Eleonora Guarnieri, Vincenzo Castiglione, Raffaele De Caterina

doi : 10.1093/eurheartj/ehad184

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Page 1842

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Corrigendum to: JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study

doi : 10.1093/eurheartj/ehad174

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Page 1843

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Corrigendum to: Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection

doi : 10.1093/eurheartj/ehad167

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Pages 1844–1845

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Erratum to: The year in cardiovascular medicine 2022: the top 10 papers in cardio-oncology

doi : 10.1093/eurheartj/ehad090

European Heart Journal, Volume 44, Issue 20, 21 May 2023, Page 1806

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