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Ischaemic heart disease: from the celebration of Heberden’s description of angina pectoris to novel therapeutic targets for angiogenesis and myocardial fibrosis
Filippo Crea
doi : 10.1093/eurheartj/ehad278
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1669–1673
‘Normal’ blood pressure is no longer a safe haven: take shelter under ‘optimal’ blood pressure
C Venkata S Ram
doi : 10.1093/eurheartj/ehad102
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1674–1675
Providing next-generation haemodynamic risk prediction through multiscale imaging of cardiovascular pressure gradients: the Horizon Europe MultiPRESS project
David Marlevi
doi : 10.1093/eurheartj/ehad062
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1676–1678
Air pollution: challenges and opportunities for cardiology
Eugene Braunwald
doi : 10.1093/eurheartj/ehac791
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1679–1681
Extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest: futile strategy or need for larger studies?
Daniela Pedicino, Tommaso Sanna
doi : 10.1093/eurheartj/ehad162
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1682–1683
Reprising Heberden’s description of angina pectoris after 250 years
William E Boden, Juan Carlos Kaski, Colin Berry
doi : 10.1093/eurheartj/ehac643
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1684–1686
Primordial non-responsiveness: a neglected obstacle to cardioprotection
Gerd Heusch, Hans Erik Bøtker, Péter Ferdinandy, Rainer Schulz
doi : 10.1093/eurheartj/ehad160
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1687–1689
Long-term outcomes of perioperative myocardial infarction/injury after non-cardiac surgery
Christian Puelacher, Danielle M Gualandro, Noemi Glarner, Giovanna Lurati Buse, Andreas Lampart, Daniel Bolliger, Luzius A Steiner, Mario Grossenbacher, Katrin Burri-Winkler, Hatice Gerhard, Elisabeth A Kappos, Olivier Clerc, Laura Biner, Zaza Zivzivadze, Christoph Kindler, Angelika Hammerer-Lercher, Miodrag Filipovic, Martin Clauss, Lorenz Gürke, Thomas Wolff, Edin Mujagic, Murat Bilici, Francisco A Cardozo, Stefan Osswald, Bruno Caramelli, Christian Mueller, for the BASEL-PMI Investigators
doi : 10.1093/eurheartj/ehac798
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1690–1701
Perioperative myocardial infarction/injury (PMI) following non-cardiac surgery is a frequent cardiac complication. Better understanding of the underlying aetiologies and outcomes is urgently needed.
Potential risks of non-cardiac peri-operative myocardial infarction/injury
Kristian Thygesen, Allan S Jaffe
doi : 10.1093/eurheartj/ehac768
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1702–1704
Rule-out of non-ST-segment elevation acute coronary syndrome by a single, pre-hospital troponin measurement: a randomized trial
Cyril Camaro, Goaris W A Aarts, Eddy M M Adang, Roger van Hout, Gijs Brok, Anouk Hoare, Laura Rodwell, Frank de Pooter, Walter de Wit, Gilbert E Cramer, Roland R J van Kimmenade, Peter Damman, Eva Ouwendijk, Martijn Rutten, Erwin Zegers, Robert-Jan M van Geuns, Marc E R Gomes, Niels van Royen on behalf of the ARTICA Investigators
doi : 10.1093/eurheartj/ehad056
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1705–1714
Patients with suspected non-ST-segment elevation acute coronary syndrome (NSTE-ACS) are routinely transferred to the emergency department (ED). A clinical risk score with point-of-care (POC) troponin measurement might enable ambulance paramedics to identify low-risk patients in whom ED evaluation is unnecessary. The aim was to assess safety and healthcare costs of a pre-hospital rule-out strategy using a POC troponin measurement in low-risk suspected NSTE-ACS patients.
To be or not to be admitted to the emergency department for chest pain? A costly dilemma
Bruna Gigante
doi : 10.1093/eurheartj/ehad116
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1715–1717
Prognostic impact of hypercoagulability and impaired fibrinolysis in acute myocardial infarction
Seung Hun Lee, Hyun Kuk Kim, Jong-Hwa Ahn, Min Gyu Kang, Kye-Hwan Kim, Jae Seok Bae, Sang Young Cho, Jin-Sin Koh, Yongwhi Park, Seok Jae Hwang, Diana A Gorog, Udaya S Tantry, Kevin P Bliden, Paul A Gurbel, Jin-Yong Hwang, Young-Hoon Jeong
doi : 10.1093/eurheartj/ehad088
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1718–1728
Atherothrombotic events are influenced by systemic hypercoagulability and fibrinolytic activity. The present study evaluated thrombogenicity indices and their prognostic implications according to disease acuity.
Determining ‘thrombogenicity’ in patients with coronary artery disease: what’s next?
Aaron Iding, Arina ten Cate-Hoek, Hugo ten Cate
doi : 10.1093/eurheartj/ehad106
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1729–1731
Vasostatin-2 associates with coronary collateral vessel formation in diabetic patients and promotes angiogenesis via angiotensin-converting enzyme 2
Xiao Lu Bao, Yang Dai, Lin Lu, Xiao Qun Wang, Feng Hua Ding, Wei Feng Shen, Ying Shen, Raffaele De Caterina
doi : 10.1093/eurheartj/ehad082
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1732–1744
Members of the chromogranin family play a role in angiogenesis. One such biologically active peptide, generated through the processing of chromogranin A, is vasostatin-2. This study aimed at assessing the association of serum vasostatin-2 levels with coronary collateral vessels (CCV) in diabetic patients with chronic total occlusions (CTO) and the effects of vasostatin-2 on angiogenesis in diabetic mice with hindlimb or myocardial ischemia.
Vasostatin-2, angiogenesis and collateral function
Ingrid Fleming
doi : /10.1093/eurheartj/ehad052
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1745–1747
Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair
Dashuai Zhu, Shuo Liu, Ke Huang, Junlang Li, Xuan Mei, Zhenhua Li, Ke Cheng
doi : 10.1093/eurheartj/ehad114
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1748–1760
Epicardium and epicardium-derived cells are critical players in myocardial fibrosis. Mesenchymal stem cell–derived extracellular vesicles (EVs) have been studied for cardiac repair to improve cardiac remodelling, but the actual mechanisms remain elusive. The aim of this study is to investigate the mechanisms of EV therapy for improving cardiac remodelling and develop a promising treatment addressing myocardial fibrosis.
Lnc-ing epicardium-derived cells to cardiac remodelling: lncRNA-TARID as a novel antifibrotic option
Xuekun Wu, Francesca Vacante, Joseph C Wu
doi : 10.1093/eurheartj/ehad058
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Pages 1761–1763
Successful bailout clipping for rare complication of anterior mitral leaflet dissection during transcatheter edge-to-edge mitral valve repair
Ai Kagase, Masanori Yamamoto, Takahiro Tokuda
doi : 10.1093/eurheartj/ehad163
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Page 1764
Plaque composition on ultra-high-resolution coronary computed tomography angiography with optical coherence tomography correlation
Tilman Emrich, Michaela Hell
doi : 10.1093/eurheartj/ehac560
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Page 1765
Resuscitated sudden cardiac arrest related to intraplaque haemorrhage and coronary artery spasm
Takeshi Nishi, Teruyoshi Kume, Shiro Uemura
doi : 10.1093/eurheartj/ehad096
European Heart Journal, Volume 44, Issue 19, 14 May 2023, Page 1766
