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Perioperative individualized hemodynamic optimization according to baseline mean arterial pressure in cardiac surgery patients: Rationale and design of the OPTIPAM randomized trial
Richard Descamps, MD a , Julien Amour, MD, PhD b , Emmanuel Besnier, MD, PhD c , Adrien Bougle, MD, PhD d , Hélène Charbonneau, MD, PhD e , Martin Charvin, MD f , Bernard Cholley, MD, PhD g , Olivier Desebbe, MD h , Jean-Luc Fellahi, MD, PhD i , Denis Frasca, MD, PhD j , François Labaste, MD, PhD k , Diane Lena, MD l , Yazine Mahjoub, MD, PhD m , Paul-Michel Mertes, MD, PhD n , Serge Molliex, MD, PhD o , Pierre-Henri Moury, MD p , Mouhamed Djahoum Moussa, MD q , Jean-Ferreol Oilleau, MD r , Alexandre Ouattara, MD, PhD s , Sophie Provenchere, MD, PhD t , Bertand Rozec, MD, PhD u , Jean-Jacques Parienti, MD, PhD v , and Marc-Olivier Fischer, MD, PhD
doi : 10.1016/j.ahj.2023.03.005
Volume 261, July 2023, Pages 10-20
Effect of rosuvastatin 20 mg versus rosuvastatin 5 mg plus ezetimibe on statin side-effects in elderly patients with atherosclerotic cardiovascular disease: Rationale and design of a randomized, controlled SaveSAMS trial
Jung-Joon Cha, MD a , Soon Jun Hong, MD a , Ju Hyeon Kim, MD a , Subin Lim, MD a , Hyung Joon Joo, MD a , Jae Hyoung Park, MD a , Cheol Woong Yu, MD a , Pil Hyung Lee, MD b , Seung Whan Lee, MD b , Cheol Whan Lee, MD b , Jae Youn Moon, MD c , Jong-Young Lee, MD d , Jung-Sun Kim, MD e , Jae Suk Park, MD f , Kyounghoon Lee, MD g , Sang Yup Lim, MD h , Jin Oh Na, MD i , Jin-Man Cho, MD j , Seok Yeon Kim, MD k , and Do-Sun Lim, MD
doi : 10.1016/j.ahj.2023.03.002
Volume 261, July 2023, Pages 45-50
Current guidelines recommend that patients with established atherosclerotic cardiovascular disease (ASCVD) use high-intensity statin therapy to lower low-density lipoprotein (LDL)-cholesterol levels by at least 50%, irrespective of age. However, in real-world practice, there is reluctance to maintain statin use in response to side-effects, particularly statin-associated muscle symptoms (SAMS). Moreover, no randomized trial has been conducted on the safety of statin therapy in elderly patients.
Screening for peripartum cardiomyopathies using artificial intelligence in Nigeria (SPEC-AI Nigeria): Clinical trial rationale and design
Demilade A. Adedinsewo, MD a , Andrea Carolina Morales-Lara, MD a , Jennifer Dugan, BA b , Wendy T. Garzon-Siatoya, MD a , Xiaoxi Yao, PhD b,c , Patrick W. Johnson, BS d , Erika J. Douglass, DrPH a , Zachi I. Attia, PhD b , Sabrina D. Phillips, MD a , Mohamad H. Yamani, MD a , Yvonne Butler Tobah, MD e , Carl H. Rose, MD e , Emily E. Sharpe, MD f , Francisco Lopez-Jimenez, MD b , Paul A. Friedman, MD b , Peter A. Noseworthy, MD b,c , and Rickey E. Carter, PhD
doi : 10.1016/j.ahj.2023.03.008
Volume 261, July 2023, Pages 64-74
Evaluation of obstructive sleep apnea among consecutive patients with all patterns of atrial fibrillation using WatchPAT home sleep testing
Eric W. Mills, MD PhD a , Michael Cassidy, BS b , Tamar Sofer, PhD b , Thomas Tadros, MD c , Paul Zei, MD c , William Sauer, MD c , Jorge Romero, MD c , David Martin, MD c , Elliott M. Antman, MD c , and Sogol Javaheri, MD MPH b Boston, MA
doi : 10.1016/j.ahj.2023.03.014
Volume 261, July 2023, Pages 95-103
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice and is associated with significant morbidity, mortality, and financial burden. Obstructive sleep apnea (OSA) is more common in individuals with AF and may impair the efficacy of rhythm control strategies including catheter ablation. However, the prevalence of undiagnosed OSA in all-comers with AF is unknown.
Meta�analysis assessing the sensitivity and specificity of 18F�FDG PET/CT for the diagnosis of prosthetic valve endocarditis (PVE) using individual patient data (IPD)
Patricia O’Gorman, MBBS, MAppSc a , Lawrence Nair, MBBS b , Nadya Kisiel, MD, FRACP c , Ian Hughes, BVSc, BSc(Vet.), PhD, MBiostats d,e , Karen Huang, MBBS a , Charlie Chia-Tsong Hsu, MBBS, FRANZCR a , Erika Fagman, MD, PhD f,g , Ruth Heying, MD, PhD h , Mar?a N Pizzi, MD, PhD i,j,k , Albert Roque, MD, PhD j,k,l,m , and Kuljit Singh, MBBS, FRACP, PhD
doi : 10.1016/j.ahj.2023.03.004
Volume 261, July 2023, Pages 21-34
Contemporary laboratory assessment of acute cardiorenal syndrome for early diagnosis: A call for action
John L. Jefferies, MD a , Csaba P. Kovesdy, MD b , and Claudio Ronco, MD c Memphis, TN; Memphis, TN; Vicenza, Italy;
doi : 10.1016/j.ahj.2023.03.007
Volume 261, July 2023, Pages 75-84
Acute cardiorenal syndrome (CRS), categorized as CRS type 1 and 3, is defined by the interplay of acute kidney injury or dysfunction and acute cardiac disease. For optimized diagnosis and management of CRS, strategies targeting multi-organ dysfunction must be adopted.
Effect of active vitamin-D on left ventricular mass index: Results of a randomized controlled trial in type 2 diabetes and chronic kidney disease
Luigi Gnudi, MD, PhD a , Nikolaos Fountoulakis, MD, PhD a , Angeliki Panagiotou, MD a , Antonella Corcillo, MD a , Giuseppe Maltese, MD a , Maria Flaquer Rife, PhD a , Ioannis Ntalas, MD, PhD b , Russell Franks, MBChB b , Amedeo Chiribiri, MBBS, PhD b , Salma Ayis, PhD c , and Janaka Karalliedde, MBBS, PhD
doi : 10.1016/j.ahj.2023.03.003
Volume 261, July 2023, Pages 1-9
Complementary evidence on the performance of coronary stents generated by a randomized controlled trial and a worldwide registry
Alexandre Gautier, MD a , Marco Roffi, MD b , Peep Laanmets, MD c , Shahzad Munir, MD d , Fazila Tun-Nesa Malik, MD e , Andrés I?iguez Romo, MD f , Gabriel Maluenda, MD g , Shoichi Kuramitsu, MD h , Michaël Angioi, MD i , William Wijns, MD, PhD j , Shigeru Saito, MD k , and Bernard Chevalier, MD a Massy, France; Geneva, Switzerland; Tallinn, Estonia; Wolverhampton, United Kingdom; Dhaka, Bangladesh; Vigo, Spain; Santiago de Chile, Chile; Kitakyushu, Japan; Nancy, France; Galway Ireland; Kanagawa, Japan
doi : 10.1016/j.ahj.2023.02.016
Volume 261, July 2023, Pages 35-44
Individual net clinical outcome with oral anticoagulation in atrial fibrillation using the ABC�AF risk scores
Ziad Hijazi, MD, PhD a,b , Johan Lindb?ck, MSc b , Jonas Oldgren, MD, PhD a,b , Alexander P. Benz, MD, MSc c,d , John H. Alexander, MD, MHS e , Stuart J. Connolly, MD c , John W. Eikelboom, MD c , Christopher B. Granger, MD e , Renato D. Lopes, MD, PhD e , Agneta Siegbahn, MD PhD b,f , and Lars Wallentin, MD, PhD
doi : 10.1016/j.ahj.2023.03.012
Volume 261, July 2023, Pages 55-63
Association of CHA2DS2-VASc and HAS-BLED to frailty and frail outcomes: From the TREAT-AF study
Krishna Pundi, MD a , Alexander C. Perino, MD a,b , Jun Fan, MS c , Natasha Din, MD, MAS c , Karolina Szummer, MD, PhD d , Paul Heidenreich, MD, MS a,c , and Mintu P. Turakhia, MD, MAS
doi : 10.1016/j.ahj.2023.03.015
Volume 261, July 2023, Pages 85-94
Relationship between the volume of cases and in-hospital mortality in patients with cardiogenic shock receiving short-term mechanical circulatory support
Takashi Araki, MD a , Toru Kondo, MD, PhD a,b , Takahiro Imaizumi, MD, PhD c,d , Yoko Sumita e , Michikazu Nakai, PhD e , Akihito Tanaka, MD, PhD a , Takahiro Okumura, MD, PhD a , Mingming Yang, MD, PhD b,f , Jawad H. Butt, MD b,g , Mark C. Petrie, MB, ChB b , and Toyoaki Murohara, MD, PhD
doi : 10.1016/j.ahj.2023.03.017
Volume 261, July 2023, Pages 109-123
Incidental detection of malignancy during preprocedural workup for transcatheter aortic valve implantation: A longitudinal cohort study
Caglayan Demirel, MD a,# , Daijiro Tomii, MD a,# , Dik Heg, PhD b , Taishi Okuno, MD a , Fabian Wieser, MD a , Thomas M. Suter, MD a , Christoph Gr?ni, MD, PhD a , Stephan Windecker, MD a , and Thomas Pilgrim, MD, MSc
doi : 10.1016/j.ahj.2023.03.011
Volume 261, July 2023, Pages 51-54
Secondary analysis of electronic opt-out consent in pragmatic research: A study design method to diversify clinical trials?
Prerna Gupta, MD a , Lisa C. Sandy, MA b , Thomas J. Glorioso, MS c , Amber Khanna, MD, MS a , Prateeti Khazanie, MD, MPH a , Larry A. Allen, MD, MHS a , Pamela N. Peterson, MD, MSPH a,d , Sheana Bull, PhD, MPH e , and Pei Jai Michael Ho, MD, PhD
doi : 10.1016/j.ahj.2023.03.010
Volume 261, July 2023, Pages 104-108
We conducted a multi-center pragmatic trial of a low-risk intervention focused on medication adherence using an opt-out consent approach, where patients could opt out by letter and then electronically. We focus on the cohort after opt-out by mail. Here, we describe that 8% of patients opted out electronically, resulting in a 92% participation rate. Patients who self-identify as Black or Hispanic were less likely to opt out in the study, and half the study cohort was female. This demographic data is useful for planning future trials employing this approach.
Clinical and cost implications of deferred testing in low-risk patients with stable chest pain: a simulation using the PROMISE trial☆
Michael G. Nanna, MD, MHS a , Eric Yow, MS b , Sreekanth Vemulapalli, MD b , Daniel B. Mark, MD b , Michelle Kelsey, MD b , Manesh R. Patel, MD b , Hussein R. Al-Khalidi, PhD b , Campbell Rogers, MD c , James E. Udelson, MD d , and Pamela S. Douglas, MD
doi : 10.1016/j.ahj.2023.02.010
Volume 261, July 2023, Pages 124-126
A novel robotic radiation shielding device for electrophysiologic procedures: A prospective study
Avishag Laish-Farkash, MD, PhD1 , Emanuel Harari, MD1 , Michael Rahkovich, MD, Yonatan Kogan, MD, Gergana Marincheva, MD, Guy Scheinman, MD, Eyal Ben-Assa, MD, and Eli I. Lev, MD
doi : 10.1016/j.ahj.2023.03.009
Volume 261, July 2023, Pages 127-136
