Clinical and Translational Gastroenterology




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Individuals With a Family History of Colorectal Cancer Warrant Tailored Interventions to Address Patient-Reported Barriers to Screening.

Jain, Shailavi MD 1; Galoosian, Artin MD 2; Wilhalme, Holly MS 3; Meshkat, Sarah MHA 4; May, Folasade P. MD, PhD, MPhil 1,2,5,6

doi : 10.14309/ctg.0000000000000583

Volume 14(5) pgs. e00583-e00572 May 2023

Population health interventions to increase colorectal cancer (CRC) screening rates often exclude individuals with a family history of CRC, and interventions to increase screening in this high-risk group are rare.

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Single-Donor and Pooling Strategies for Fecal Microbiota Transfer Product Preparation in Ulcerative Colitis: A Systematic Review and Meta-analysis.

Levast, Benoit PhD 1; Fontaine, Mathieu PhD 2; Nancey, Stephane MD 3; Dechelotte, Pierre MD 4; Dore, Joel PhD 5; Lehert, Philippe PhD 6,7

doi : 10.14309/ctg.0000000000000568

Patients with ulcerative colitis (UC) have a less diverse microbiome than healthy subjects. Multiple studies have evaluated fecal microbiota transfer (FMT) in these patients using different methods of product preparation, doses, and routes of administration.

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Identification of CD8+ T-Cell-Immune Cell Communications in Ileal Crohn's Disease.

Duong, Han G. BS 1,*; Choi, Eunice J. BS 2,*; Hsu, Paul MD, PhD 1,*; Chiang, Natalie R. 1; Patel, Shefali A. BS 1; Olvera, Jocelyn G. BS 1; Liu, Yi Chia BS 1; Lin, Yun Hsuan MS 1; Yao, Priscilla BS 1; Wong, William H. BS 1; Indralingam, Cynthia S. MS 1; Tsai, Matthew S. MD, PhD 1,3; Boland, Brigid S. MD 1; Wang, Wei PhD 2,4; Chang, John T. MD 1,3

doi : 10.14309/ctg.0000000000000576

Crohn's disease (CD) is a major subtype of inflammatory bowel disease (IBD), a spectrum of chronic intestinal disorders caused by dysregulated immune responses to gut microbiota.

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Safety and Tolerability of High-Resolution Esophageal Manometry in Children and Adults.

Oh, Janice E. MD, MSc 1; Huang, Lizhou MD 2; Takakura, Will MD 3; Khuu, Kevin BA 4; Wang, Jiajing PhD 5; Kowalewski, Edward BSBA 4; Huang, Shao-Chi BS 4; Chang, Bianca MD 5,6; Pimentel, Mark MD 5,6; Rezaie, Ali MD, MSc 5,6

doi : 10.14309/ctg.0000000000000571

While high-resolution manometry (HRM) is widely accepted as a safe procedure, no study has assessed the safety profile of HRM in clinical practice.

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Transarterial Chemoembolization Combined With Apatinib Plus PD-1 Inhibitors for Hepatocellular Carcinoma With Portal Vein Tumor Thrombus: A Multicenter Retrospective Study.

Xia, Wei-Li MD 1; Zhao, Xiao-Hui MD 1; Guo, Yuan MD 1; Hu, Hong-Tao MD 1; Cao, Guang-Shao MD 2; Li, Zhen MD 3; Fan, Wei-Jun MD 4; Xu, Shi-Jun PhD 1; Li, Hai-Liang MD 1

doi : 10.14309/ctg.0000000000000581

The aim of this study was to compare transarterial chemoembolization (TACE) combined with apatinib and PD-1 inhibitors (TACE-AP) with TACE combined with apatinib alone (TACE-A) in the treatment of hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) and to explore the prognostic factors affecting the survival of patients.

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Helicobacter pylori Seropositivity, ABO Blood Type, and Pancreatic Cancer Risk From 5 Prospective Cohorts.

Lee, Alice A. MD 1; Wang, Qiao-Li MD, PhD 2; Kim, Jihye PhD 3; Babic, Ana PhD 2; Zhang, Xuehong MD, ScD 4,5; Perez, Kimberly MD 2; Ng, Kimmie MD, MPH 2; Nowak, Jonathan MD, PhD 6; Rifai, Nader PhD 7; Sesso, Howard D. ScD, MPH 3,8,9; Buring, Julie E. ScD 3,8; Anderson, Garnet L. PhD 10; Wactawski-Wende, Jean PhD 11; Wallace, Robert PhD 12; Manson, JoAnn E. MD, PhD 3,4,8; Giovannucci, Edward L. MD, ScD 3,5; Stampfer, Meir J. MD, DrPH 3,4,5; Kraft, Peter PhD 3,13; Fuchs, Charles S. MD, MPH 14,15; Yuan, Chen ScD 2; Wolpin, Brian M. MD, MPH 2

doi : 10.14309/ctg.0000000000000573

Helicobacter pylori infection may be a risk factor for pancreatic cancer, particularly infection by strains without the cytotoxin-associated gene A (CagA) virulence factor. Non-O blood type is a known risk factor for pancreatic cancer, and H.

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Performance of Cytomegalovirus Real-Time Polymerase Chain Reaction Assays of Fecal and Plasma Specimens for Diagnosing Cytomegalovirus Colitis.

Sattayalertyanyong, Onuma MD 1,2; Limsrivilai, Julajak MD, MSc 1; Phaophu, Phutthaphorn MS 1; Subdee, Nichcha BD 1; Horthongkham, Navin PhD 3; Pongpaibul, Ananya MD 4; Angkathunyakul, Napat MD 4; Chayakulkeeree, Methee MD, PhD 5; Pausawasdi, Nonthalee MD 1; Charatcharoenwitthaya, Phunchai MD, MSc 1

doi : 10.14309/ctg.0000000000000574

Cytomegalovirus (CMV) viral load detected by real-time polymerase chain reaction (PCR) in plasma or stool may facilitate detection of CMV colitis.

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Social Network Diversity and the Daily Burden of Inflammatory Bowel Disease.

Greene-Higgs, LaVana MD 1; Jordan, Ariel MD 1; Sheehan, Jessica MD, MS 2; Berinstein, Jeffrey MD, MS 2; Admon, Andrew J. MD, MS 3,4; Waljee, Akbar K. MD, MS 2,4; Riehl, Megan PhD 2; Piette, John PhD 4,5; Resnicow, Kenneth PhD 5; Higgins, Peter D. MD, PhD, MS 2; Cohen-Mekelburg, Shirley MD, MS 2,4

doi : 10.14309/ctg.0000000000000572

To examine the association between social network, daily inflammatory bowel disease (IBD) burden, and related cognitive factors such as loneliness and psychological well-being.

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