Cornea




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Corneal Classics: The Most-Cited Article in the 36-Year History of Cornea

Perry, Henry D. MD*,†

doi : 10.1097/ICO.0000000000002606

Cornea: March 2021 - Volume 40 - Issue 3 - p 269

To describe the most cited article in the 36 year history of Cornea.

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Descemet-Stripping Automated Endothelial Keratoplasty

Gorovoy, Mark S. MD

doi : 10.1097/ICO.0000000000002688

Cornea: March 2021 - Volume 40 - Issue 3 - p 270-273

To evaluate the speed of visual recovery in 16 consecutive patients with corneal endothelial dysfunction who received Descemetstripping automated endothelial keratoplasty (DSAEK).

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Future of Corneal Donation and Transplantation: Insights From the COVID-19 Pandemic

AlMutlak, Mohammed MBBS*,†; Li, Jennifer Y. MD‡,§; Bin Helayel, Halah MBBS¶; Fairaq, Rafah MBBS?

doi : 10.1097/ICO.0000000000002538

Cornea: March 2021 - Volume 40 - Issue 3 - p 274-276

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Ethylenediaminetetraacetic Acid Chelation in Herpes Zoster Ophthalmicus Is Associated With a High Rate of Corneal Melt and Perforation

Trollip, Jessica C. MBChB*; Meyer, Jay J. MD, MPH†,‡; McGhee, Charles N. J. PhD, DSc, FRCOphth, FRANZCO†,‡; Liu, Kevin MBChB†,‡; Danesh-Meyer, Helen V. PhD, FRANZCO†,‡; Niederer, Rachael L. PhD, FRANZCO†,‡

doi : 10.1097/ICO.0000000000002619

Cornea: March 2021 - Volume 40 - Issue 3 - p 277-281

To examine the rate and risk factors for band keratopathy after herpes zoster ophthalmicus (HZO) and the outcomes of ethylenediaminetetraacetic acid (EDTA) treatment.

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A Novel Epidemiological Approach to Geographically Mapping Population Dry Eye Disease in the United States Through Google Trends

Azzam, Daniel B. BS*; Nag, Nitish PhD*,†; Tran, Julia BS*; Chen, Lauren BS*; Visnagra, Kaajal BS*; Marshall, Kailey OD‡; Wade, Matthew MD*

doi : 10.1097/ICO.0000000000002579

Cornea: March 2021 - Volume 40 - Issue 3 - p 282-291

Our study fills the spatiotemporal gaps in dry eye disease (DED) epidemiology by using Google Trends as a novel epidemiological tool for geographically mapping DED in relation to environmental risk factors.

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Optimizing Visualization of Descemet Membrane Endothelial Keratoplasty Tissue: Assessing the Impact of Trypan Blue Exposure on Stain Duration and Corneal Endothelial Cell Function

Ling, Jennifer J. MD*,†,‡; Kyrillos, Ralph MD§; Burckart, Kimberlee A. MD, PhD*,†; Aldrich, Benjamin T. PhD*,†,‡; Skeie, Jessica M. PhD*,†,‡; Schmidt, Gregory A. MBA, CEBT†; Conwell, Chris CEBT§; Ramirez, Tiffany CEBT§; Reed, Cynthia R. RN, PhD†; Zimmerman, M. Bridget PhD¶; Greiner, Mark A. MD*,†,‡; Li, Jennifer Y. MD§

doi : 10.1097/ICO.0000000000002440

Cornea: March 2021 - Volume 40 - Issue 3 - p 292-298

To assess how trypan blue staining affects Descemet membrane endothelial keratoplasty (DMEK) graft visibility and corneal endothelial cell (CEC) mitochondrial respiration.

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Anterior Segment Surgeries Under Topical Fresh Frozen Plasma Treatment in Ligneous Conjunctivitis

Ozbek-Uzman, Selma MD*; Yalniz-Akkaya, Zuleyha MD*; Nurozler Tabakci, Burcu MD†; Singar, Evin MD*; Burcu, Ayse MD*

doi : 10.1097/ICO.0000000000002573

Cornea: March 2021 - Volume 40 - Issue 3 - p 299-302

To evaluate the efficacy of topical fresh frozen plasma (FFP) therapy on clinical symptoms, findings, and prognosis after anterior segment surgeries in patients with ligneous conjunctivitis (LC).

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Comparison of Visual, Tomographic, and Biomechanical Outcomes of 360 Degrees Intracorneal Ring Implantation With and Without Corneal Crosslinking for Progressive Keratoconus: A 5-Year Follow-up

Mohammadpour, Mehrdad MD*; Khoshtinat, Narges MD*; Khorrami-Nejad, Masoud PhD*,†

doi : 10.1097/ICO.0000000000002407

Cornea: March 2021 - Volume 40 - Issue 3 - p 303-310

To evaluate the long-term (5 years) results of 360 degrees intracorneal ring (ICR) implantation with and without corneal crosslinking (CXL) in patients with progressive keratoconus (KCN).

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One-Year Clinical Outcomes of Preloaded Descemet Membrane Endothelial Keratoplasty Versus Non-Preloaded Descemet Membrane Endothelial Keratoplasty

B?hm, Myriam S. MD, MSc; Wylegala, Adam MD; Leon, Pia MD; Ong Tone, Stephan MDCM, PhD, FRCSC; Ciolino, Joseph B. MD; Jurkunas, Ula V. MD

doi : 10.1097/ICO.0000000000002430

Cornea: March 2021 - Volume 40 - Issue 3 - p 311-319

To compare the one-year outcomes of preloaded Descemet membrane endothelial keratoplasty (pDMEK) and non-preloaded DMEK (n-pDMEK) in patients with Fuchs endothelial corneal dystrophy (FECD).

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Descemet Stripping Only Supplemented With Topical Ripasudil for Fuchs Endothelial Dystrophy 12-Month Outcomes of the Sydney Eye Hospital Study

Moloney, Gregory MBBS (Hons), BSc (Med), MMed, FRANZCO, FRCSC*,†; Garcerant Congote, Daniel MD†; Hirnschall, Nino MD, PhD, FEBO‡; Arsiwalla, Tasneem MBBS (Hons), DNB (Ophthalmology), FICO†; Luiza Mylla Boso, Ana MD†; Toalster, Nicholas BAppSci Optom (Hons), MBBS (Hons), FRANZCO†; D'Souza, Mario MSc, PhD*; Devasahayam, Raj N. BApp Sci*,†,§

doi : 10.1097/ICO.0000000000002437

Cornea: March 2021 - Volume 40 - Issue 3 - p 320-326

To report early safety and efficacy of Descemet stripping only (DSO) supplemented with ripasudil.

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Cosmetic Keratopigmentation in Sighted Eyes: Medium- and Long-term Clinical Evaluation

D'Oria, Francesco MD*,†,‡; Alio, Jorge L. MD, PhD, FEBO*,†; Rodriguez, Alejandra E. MSc, PhD*; Amesty, Maria A. MD, PhD§; Abu-Mustafa, Sabat K. MD¶

doi : 10.1097/ICO.0000000000002417

Cornea: March 2021 - Volume 40 - Issue 3 - p 327-333

To assess the medium- and long-term outcomes of keratopigmentation (KTP) as a surgical alternative to change the cosmetic appearance of healthy eyes.

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Serum 25-Hydroxy Vitamin D, Vitamin B12, and Folic Acid Levels in Progressive and Nonprogressive Keratoconus

Aslan, Mehmet G?khan MD*; F?nd?k, Hüseyin MD*; Okutucu, Murat MD*; Ayd?n, Emre MD*; Oruç, Yavuz MD†; Arpa, Medeni MD‡; Uzun, Feyzahan MD*

doi : 10.1097/ICO.0000000000002475

Cornea: March 2021 - Volume 40 - Issue 3 - p 334-341

To evaluate the serum 25-hydroxy vitamin D, vitamin B12, and folic acid (FA) levels in progressive and nonprogressive patients with keratoconus (KCN).

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Absence of Severe Acute Respiratory Syndrome-Coronavirus-2 RNA in Human Corneal Tissues

Bayyoud, Tarek MD*; Iftner, Angelika†; Iftner, Thomas PhD†; Bartz-Schmidt, Karl Ulrich MD*; Rohrbach, Jens Martin MD*; Ueffing, Marius PhD*,‡; Schindler, Michael PhD†; Thaler, Sebastian MD‡

doi : 10.1097/ICO.0000000000002479

Cornea: March 2021 - Volume 40 - Issue 3 - p 342-347

To examine corneal tissue for severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) positivity regarding implications for tissue procurement, processing, corneal transplantation, and ocular surgery on healthy patients. We performed quantitative reverse transcription-polymerase chain reaction qRT-PCR-testing for SARS-CoV-2 RNA on corneal stroma and endothelium, bulbar conjunctiva, conjunctival fluid swabs, anterior chamber fluid, and corneal epithelium of coronavirus disease 2019 (COVID-19) postmortem donors.

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Detection of Coronavirus in Tear Samples of Hospitalized Patients With Confirmed SARS-CoV-2 From Oropharyngeal Swabs

Dutescu, R. Michael MD*; Banasik, Peter†; Schildgen, Oliver MD‡; Schrage, Norbert MD*; Uthoff, Daniel*

doi : 10.1097/ICO.0000000000002562

Cornea: March 2021 - Volume 40 - Issue 3 - p 348-350

This study was designed to detect CoV-RNA in the tears of polymerase chain reaction (PCR)-confirmed SARS-CoV-2 positive patients.

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New Freeware for Image Analysis of Lissamine Green Conjunctival Staining

Courrier, Emilie PhD*; Renault, Didier PhD*; Dib, Elian*,†; Urrea, Caroline MD‡; Kaspi, Mathilde MD‡; Fournier, Corinne PhD†; Lépine, Thierry PhD*,†; Chiambaretta, Frédéric MD, PhD§; Hor, Guillaume*; He, Zhiguo PhD*; Garcin, Thibaud MD, PhD*,‡; Thuret, Gilles MD, PhD*,‡; Gain, Philippe MD, PhD*,‡

doi : 10.1097/ICO.0000000000002617

Cornea: March 2021 - Volume 40 - Issue 3 - p 351-357

Lissamine green (LG) is often used in addition to fluorescein to assess the severity of conjunctival damage in dry eye syndrome, which is graded manually. Our purpose was to describe an algorithm designed for image analysis of LG conjunctival staining.

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Effect of 808-nm Laser Photobiomodulation Treatment in Blepharitis Rat Model

Kim, Hoon PhD; Kim, Hong-Bee BS; Seo, Jae-Hwi MA; Kim, Hongbin MA; Cho, Kyong Jin MD, PhD

doi : 10.1097/ICO.0000000000002596

Cornea: March 2021 - Volume 40 - Issue 3 - p 358-363

Blepharitis, simply defined as eyelid inflammation, is one of the common ocular conditions associated with discomfort and irritation. Because blepharitis causes meibomian gland dysfunction and dry eye, this study aimed to confirm the effect of photobiomodulation (PBM) on blepharitis.

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Characterization of Endothelial Cell Loss in Pre-Descemet Endothelial Keratoplasty Graft Preparation

Bedard, Peter MS*,†; Hou, Joshua H. MD*,†

doi : 10.1097/ICO.0000000000002536

Cornea: March 2021 - Volume 40 - Issue 3 - p 364-369

To characterize the pattern and factors affecting endothelial cell loss (ECL) in pre-Descemet Endothelial Keratoplasty (PDEK) graft preparation.

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Coexistence of Meesmann Corneal Dystrophy and a Pseudo-Unilateral Lattice Corneal Dystrophy in a Patient With a Novel Pathogenic Variant in the Keratin K3 Gene: A Case Report

Abad-Morales, V?ctor PhD*,†; Barbany, Miriam MD*,‡; Gris, Oscar MD, PhD*,‡; Güell, José Luis MD, PhD*,‡; Pomares, Esther PhD*,†

doi : 10.1097/ICO.0000000000002620

Cornea: March 2021 - Volume 40 - Issue 3 - p 370-372

This study aims to clinically and genetically report a case of coexisting Meesmann corneal dystrophy (MECD) and pseudo-unilateral lattice corneal dystrophy (LCD).

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Identification of a New Genetic Mutation Associated With Peters Anomaly

Faber, Hanna MD, PhD*; Puk, Oliver PhD†; Holz, Anja PhD†; Biskup, Saskia MD, PhD†; Voykov, Bogomil MD*

doi : 10.1097/ICO.0000000000002611

Cornea: March 2021 - Volume 40 - Issue 3 - p 373-376

To report a new genetic mutation in the COL4A1 gene, which was identified in a baby girl with Peters anomaly (PA), a rare anterior segment mesenchymal dysgenesis, which is characterized by unilateral or bilateral corneal opacities often accompanied by glaucoma, cataract, and systemic malformations and associated with various genetic mutations.

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Paraneoplastic Conjunctival Acanthosis Nigricans: A Case Report

Huang, Natalie MD; Yin, Han Y. MD; Swan, Robert MD

doi : 10.1097/ICO.0000000000002513

Cornea: March 2021 - Volume 40 - Issue 3 - p 377-379

To report a patient who presented with red eye and diffuse palpebral conjunctival thickening and papillary growth bilaterally.

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Tintelnotia destructans Keratitis: A Clinicopathological Report and Review of the Literature

Kaufmann, Claude MD*; Arnold, Mihaela†; Schipf, Alexander MD‡; Bruderer, Vera L. VMD§; Iselin, Katja C. MD*

doi : 10.1097/ICO.0000000000002550

Cornea: March 2021 - Volume 40 - Issue 3 - p 380-382

To present the first clinicopathological report of Tintelnotia destructans keratitis, a filamentous fungus and as of yet uncommon virulent ocular pathogen.

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A Patient With Bilateral Conjunctivitis Positive for SARS-CoV-2 RNA in a Conjunctival Sample

Sirakaya, Ender MD*; Sahiner, Mustafa MD†; Aslan Sirakaya, Hatice MD‡

doi : 10.1097/ICO.0000000000002485

Cornea: March 2021 - Volume 40 - Issue 3 - p 383-386

To present a patient with bilateral conjunctivitis, testing positive for viral RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both nasopharyngeal and conjunctival samples.

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Descemet Membrane Endothelial Keratoplasty Using a Pull-Through Technique With Novel Infusion Forceps

Jabbour, Samir MD, CM, FRCSC; Jun, Albert S. MD, PhD; Shekhawat, Nakul S. MD, MPH; Woreta, Fasika A. MD, MPH; Krick, Tracy W. MD; Srikumaran, Divya MD

doi : 10.1097/ICO.0000000000002558

Cornea: March 2021 - Volume 40 - Issue 3 - p 387-392

To describe a surgical technique of Descemet membrane endothelial keratoplasty (DMEK) using an endothelium-in pull-through technique with novel infusion forceps and report 6-month clinical outcomes.

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Lamellar Dissection Technique for Traumatic Cataract With Corneal Incarceration

Hamad, Julia B.*; Sivaraman, Kavitha R. MD*,†; Snyder, Michael E. MD*,†

doi : 10.1097/ICO.0000000000002544

Cornea: March 2021 - Volume 40 - Issue 3 - p 393-397

To describe a technique for traumatic cataract management for cases in which part of the anterior capsule has been incarcerated into a healed corneal laceration.

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Should Donors Consent to Export Their Corneas? Examination of Eye Tissue and Eye Care Sector Opinion

Machin, Heather MBA*,†; Sutton, Gerard MD‡,§; Baird, Paul N. PhD†

doi : 10.1097/ICO.0000000000002559

Cornea: March 2021 - Volume 40 - Issue 3 - p 398-403

Corneal tissue international activity is only possible because of the willingness of export populations to donate their corneas on their death. Current predonation public education campaigns and at-the-point-of-donation consent practice generally includes consent for transplantation, research, and/or training. It is unclear whether a consent-for-export step is universally included in the consent process or, indeed, whether it should. We interviewed eye tissue and eye care professionals from around the world, who exported, imported, or did neither to understand current consent-for-export awareness and determine opinion on future practice.

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Slit-Lamp Infection Protector Cover for COVID-19

Trehan, H. S. MS; Sharma, Vijay K. MSOphth

doi : 10.1097/ICO.0000000000002456

Cornea: March 2021 - Volume 40 - Issue 3 - p e2

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Absence of Severe Acute Respiratory Syndrome Coronavirus 2 RNA in Human Corneal Donor Tissues: Implications for Transplantation

Ferrari, Stefano PhD*; Del Vecchio, Claudia PhD†; Bosio, Lorenzo MSc*; Zorzi, Ilaria MD*; Crisanti, Andrea MD†; Ponzin, Diego MD*

doi : 10.1097/ICO.0000000000002594

Cornea: March 2021 - Volume 40 - Issue 3 - p e3-e4

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Comment on: “Descemet-Stripping Automated Endothelial Keratoplasty Centration and Interface Folds: Surgical Management”

Yu, Angeli Christy MD*,†,‡; Busin, Massimo MD*,†,‡

doi : 10.1097/ICO.0000000000002592

Cornea: March 2021 - Volume 40 - Issue 3 - p e4-e5

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Reply

Gadhvi, Kunal A. MBBS, FRCOphth*; Pagano, Luca MD*; Menassa, Nardine MD, FRCOphth*; Borroni, Davide MD*; Kaye, Stephen B. MD, FRCS, FRCOphth*,†; Levis, Hannah J. PhD†; Romano, Vito MD*,†

doi : 10.1097/ICO.0000000000002600

Cornea: March 2021 - Volume 40 - Issue 3 - p e5

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Transportation of Preloaded DMEK Grafts

Rickmann, Annekatrin MD; Wahl, Silke PhD; Schulz, André; Szurman, Peter MD

doi : 10.1097/ICO.0000000000002597

Cornea: March 2021 - Volume 40 - Issue 3 - p e5-e6

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Short-Term Interim Results of Clinical Outcomes and Complications After Implantation of Boston Keratoprosthesis in Japanese Patients

Milad, Daniel MDc*; Harissi-Dagher, Mona MD†

doi : 10.1097/ICO.0000000000002608

Cornea: March 2021 - Volume 40 - Issue 3 - p e6-e7

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Reply

Ono, Takashi MD; Mori, Yosai MD, PhD; Minami, Keiichiro PhD; Miyata, Kazunori MD, PhD

doi : 10.1097/ICO.0000000000002630

Cornea: March 2021 - Volume 40 - Issue 3 - p e7

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