Journal of Neuro-Ophthalmology




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Sociodemographic and Geographic Variation in Access to Neuro-Ophthalmologists in the United States.

Xue, Katie BA; Feng, Yilin MD; Tam, Vicky MA; Lin, Chun Chieh PhD, MBA; De Lott, Lindsey B. MD, MS; Hamedani, Ali G. MD, MHS

doi : 10.1097/WNO.0000000000001821

Volume 43(2) pgs. 149-293,e41-e66 June 2023

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A Validated Method to Identify Neuro-Ophthalmologists in a Large Administrative Claims Database.

Feng, Yilin MD; Lin, Chun Chieh PhD, MBA; Hamedani, Ali G. MD, MHS; De Lott, Lindsey B. MD, MS

doi : 10.1097/WNO.0000000000001794

Validated methods to identify neuro-ophthalmologists in administrative data do not exist. The development of such method will facilitate research on the quality of neuro-ophthalmic care and health care utilization for patients with neuro-ophthalmic conditions in the United States.

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Deep Learning System Outperforms Clinicians in Identifying Optic Disc Abnormalities.

Vasseneix, Caroline MD; Nusinovici, Simon PhD; Xu, Xinxing PhD; Hwang, Jeong-Min MD; Hamann, Steffen MD, PhD; Chen, John J. MD, PhD; Loo, Jing Liang MBBS, MMed, FRCS(Ed); Milea, Leonard BA; Tan, Kenneth B.K. MBBS, MMed EM; Ting, Daniel S.W. MD, PhD; Liu, Yong PhD; Newman, Nancy J. MD; Biousse, Valerie MD; Wong, Tien Ying MD, PhD; Milea, Dan MD, PhD; Najjar, Raymond P. PhD; for the BONSAI (Brain and Optic Nerve Study With Artificial Intelligence) Group; Gohier, Philippe MD; Miller, Neil MD; Vanikieti, Kavin MD; La Morgia, Chiara MD, PhD; Rougier, Marie-Benedicte MD, PhD; Ambika, Selvakumar DO, DNB; Fonseca, Pedro MD; Lagreze, Wolf Alexander MD; Sanda, Nicolae MD, PhD; Chiquet, Christophe MD, PhD; Yang, Hui MD, PhD; Chan, Carmen K. M. MRCP, FRCSEd(Ophth); Cheung, Carol Y. PhD; Ha Chau, Tran Thi MD; Jurkute, Neringa MD, FEBO; Yu-Wai-Man, Patrick MB, BS, FRCPath, FRCOphth, PhD; Kho, Richard MD; Jonas, Jost B MD; Vignal-Clermont, Catherine MD; Kim, Dong Hyun MD; Yang, Hee Kyung MD; Aung, Tin MD, PhD; Singhal, Shweta MBBS, PhD; Tow, Sharon MBBS, FRCSEd; Nongpiur, Monisha Esther MD; Perera, Shamira MD; Narayanaswamy, Arun MD; Thirugnanam, Umapathi N. MD; Fraser, Clare L. MBBS, MMed, FRANZCO; Mejico, Luis J. MD; Fard, Masoud Aghsaei MD

doi : 10.1097/WNO.0000000000001800

The examination of the optic nerve head (optic disc) is mandatory in patients with headache, hypertension, or any neurological symptoms, yet it is rarely or poorly performed in general clinics.

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Imaging Amyloid and Tau in the Retina: Current Research and Future Directions.

Tang, Mira Y.; Blazes, Marian S. MD; Lee, Cecilia S. MD, MS

doi : 10.1097/WNO.0000000000001786

The retina is a key focus in the search for biomarkers of Alzheimer's disease (AD) because of its accessibility and shared development with the brain.

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Improvement of Retinal Capillary Function After High-Speed Circuit Resistance Training in Healthy Older Adults.

Jiang, Hong MD, PhD; Signorile, Joseph F. PhD; Simms, Ava-Gaye MBBS; Wang, Jianhua MD, PhD

doi : 10.1097/WNO.0000000000001679

To determine the retinal capillary function (RCF, the efficiency of blood flow transferring in the capillary network) and its relation to cognitive function in healthy older people without known cognitive impairment following an 8-week high-speed circuit resistance training program (HSCT).

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Peripapillary Vessel Density in Relation to Optic Disc Drusen: A Multimodal Optical Coherence Tomography Study.

Lykkebirk, Lea MD; Wessel Lindberg, Anne-Sofie PhD; Karlesand, Isabelle MD; Heiberg, Mathias MD; Malmqvist, Lasse MD, PhD; Hamann, Steffen MD, PhD

doi : 10.1097/WNO.0000000000001667

Optic disc drusen (ODD) are acellular calcified deposits within the optic nerve head known to cause visual field defects. An emerging gold standard for the diagnosis of ODD is enhanced depth imaging optical coherence tomography (EDI-OCT).

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Assessment of the Optic Disc and Retinal Microvasculature by Optical Coherence Tomography Angiography in Patients With Pediatric Migraine.

Kurtul, Bengi Ece MD; Sipal, Cansu MD; Akbas, Yilmaz MD

doi : 10.1097/WNO.0000000000001697

Migraine, as a chronic neurovascular disease, is known to be a risk factor for retinal and optic nerve head damage. Herein, we aimed to evaluate the optic disc and retinal microvasculature in pediatric migraine (PM) patients using optical coherence tomography angiography (OCTA).

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Idiopathic Intracranial Hypertension and Socioeconomic Status in the Greater Toronto Area, Canada.

Eshtiaghi, Arshia BHSc, MD(C); Margolin, Edward A. MD; Micieli, Jonathan A. MD

doi : 10.1097/WNO.0000000000001680

Previous studies have identified an association between obesity and socioeconomic variables such as poverty, minority status, and a low level of education. Because obesity is a major risk factor for the development of idiopathic intracranial hypertension (IIH), this study aims to identify and assess relationships between socioeconomic and geographic variables in patients with IIH in Canada.

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Intra-arterial Thrombolysis for Acute Retinal Ischemia: A Retrospective, Observational, Cohort Study.

Gao, Yuan MD; Zhao, Wenbo MD; Wu, Di PhD; Feng, Wayne MD; Grory, Brian Mac MD; Guo, Wenting MD; Zhang, Dawei MD; Su, Xinjie MD; Ji, Xunming MD, PhD; Zhang, Xuxiang MD, PhD

doi : 10.1097/WNO.0000000000001710

To determine whether intra-arterial thrombolysis (IAT) within 16 hours after the onset of symptoms is feasible and associated with better visual outcomes in patients with acute retinal ischemia (ARI).

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Transient Bilateral Central Scotoma on Awakening: A Distinct Phenomenon.

Sanchez Moreno, Francisco R. MD; Mansukhani, Sasha A. MBBS; Bhatti, M. Tariq MD; Chen, John J. MD, PhD

doi : 10.1097/WNO.0000000000001718

Transient vision loss can be an alarming symptom owing to potentially serious etiologies such as thromboembolism or giant cell arteritis. Transient monocular vision loss (TVML) on awakening has been recently described as a benign phenomenon (Bouffard et al, 2017).

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Ocular Findings of Cryptococcal Meningitis in Previously Healthy Adults.

Okeagu, Chinwenwa U. MD; Anjum, Seher H. MD; Vitale, Susan PhD, MHS; Wang, Jing MS; Singh, Deven BA; Rosen, Lindsey B. BS; Magone, M. Teresa MD; Fitzgibbon, Edmond J. MD; Williamson, Peter R. MD, PhD

doi : 10.1097/WNO.0000000000001713

Patients with cryptococcal meningitis (CM) often have ocular manifestations; although data are describing these findings in nonimmunosuppressed, previously healthy individuals are scarce.

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Visual Pathway Involvement in NMDA Receptor Encephalitis: A Clinical, Optical Coherence Tomography, and 18-Fluorodeoxyglucose PET/CT Approach.

Kalaitzidis, Grigorios MD; Filippatou, Angeliki MD; Fioravante, Nicholas Bsc; Rothman, Alissa MD; Sotirchos, Elias S. MD; Vasileiou, Eleni MD; Ehrhardt, Henrik MBBCh, MSc; Quiroga, Agustina BA; Pellegrini, Nicole BA; Murphy, Olwen C. MD; Moussa, Hussein MD; Ladakis, Dimitrios C. MD; Lambe, Jeffrey MD; Fitzgerald, Kathryn C. ScD; Solnes, Lilja MD; Venkatesan, Arun MD, PhD; Calabresi, Peter A. MD; Saidha, Shiv MBBCh; Probasco, John C. MD

doi : 10.1097/WNO.0000000000001696

Anti-NMDA receptor (NMDAR) encephalitis patients have been reported to exhibit visual dysfunction without retinal thinning. The objective of our study was to examine the involvement of the visual pathway structure and function in anti-NMDAR encephalitis by assessing postrecovery visual function and retinal structure, and acute-phase occipital cortex function.

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Analysis of Retinal Structure and Electrophysiological Function in Visual Snow Syndrome: An Exploratory Case Series.

Zaroban, Nathaniel J. MD; Kedar, Sachin MD; Anderson, David PhD; Vuppala, Amrita-Amanda D. MD

doi : 10.1097/WNO.0000000000001757

Visual snow (VS) is a rare but distressing phenomenon of persistent granular or pixelated visual distortions that may occur in isolation or as a component of visual snow syndrome (VSS).

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Comparison of a New Head Mount Virtual Reality Perimeter (C3 Field Analyzer) With Automated Field Analyzer in Neuro-Ophthalmic Disorders.

Odayappan, Annamalai DNB; Sivakumar, Priya MS; Kotawala, Sandal BTech; Raman, Ramalakshmi MSc; Nachiappan, Sivagami DO; Pachiyappan, Arulmozhivarman PhD; Venkatesh, Rengaraj DNB

doi : 10.1097/WNO.0000000000001714

Automated perimetry in neurologically disabled patients is a challenge. We have devised a patient-friendly virtual reality perimeter, the C3 field analyzer (CFA).

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FLUORESCE: A Pilot Randomized Clinical Trial of Fluoxetine for Vision Recovery After Acute Ischemic Stroke.

Schneider, Colleen L. PhD; Prentiss, Emily K. BS; Busza, Ania MD, PhD; Williams, Zoe R. MD; Mahon, Bradford Z. PhD; Sahin, Bogachan MD, PhD

doi : 10.1097/WNO.0000000000001654

Poststroke homonymous hemianopia is disabling, and complete spontaneous recovery is rare. In this randomized, placebo-controlled, double-blind, pilot clinical trial, we tested whether fluoxetine enhances vision recovery after stroke.

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Transsynaptic Ganglion Cell Degeneration in Adult Patients After Occipital Lobe Stroke.

Donaldson, Laura MD, PhD; Chen, Michael BS; Margolin, Edward MD

doi : 10.1097/WNO.0000000000001657

Loss of retinal ganglion cells after occipital lobe damage is known to occur through transsynaptic retrograde degeneration in congenital lesions; however, studies of this phenomenon in acquired pathology, such as strokes affecting postgenicular visual pathway, are scant.

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Vascular Risk Factors in Isolated Microvascular Ischemic Third Nerve Palsy: A Population-Based Study.

Zhao, Bingying MD; Bhatti, M. Tariq MD; Fang, Chengbo MD; Hodge, David O. MS; Holmes, Jonathan M. BM, BCh; Mohney, Brian G. MD; Chen, John J. MD, PhD

doi : 10.1097/WNO.0000000000001755

Although presumed microvascular third nerve palsies (TNP) have been associated with vascular risk factors and/or stroke, these associations have not been explored in a population-based cohort.

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Split-Tendon Medial Transposition of Lateral Rectus for Pediatric Complete Oculomotor Palsy.

Zhang, Kevin X. MD, PhD; Varma, Hersh MD; Cao, Yuying BS; Shah, Veeral S. MD, PhD

doi : 10.1097/WNO.0000000000001731

Split-tendon medial transposition of lateral rectus (STMTLR) for complete oculomotor palsy can correct large angles of exotropia in adults, but outcomes are variable, and complications are frequent.

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What Is the Best Surgical Intervention for Patients With Idiopathic Intracranial Hypertension?.

Subramanian, Prem S. MD, PhD; Turbin, Roger E. MD, FACS; Dinkin, Marc J. MD; Lee, Andrew G. MD; Van Stavern, Gregory P. MD

doi : 10.1097/WNO.0000000000001856

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Centripetal Nystagmus, Slow Saccades, Cerebellar Ataxia, and Parkinsonism in a Patient With Anti-GAD65-Associated Stiff Person Syndrome Spectrum Disorder.

Hac, Nicholas E. F. MD; Murphy, Olwen C. MBBCh; Butala, Ankur A. MD; Newsome, Scott D. DO; Gold, Daniel R. DO

doi : 10.1097/WNO.0000000000001774

AB A 68-year-old woman with positional dizziness and progressive imbalance presented for vestibular evaluation. Examination was notable for spontaneous downbeat nystagmus (DBN), horizontal and vertical gaze-evoked nystagmus (GEN) with centripetal and rebound nystagmus, and positional apogeotropic nystagmus.

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A Great Conversation With Larry Frohman.

Seay, Meagan D. DO; Calix, Rachel A. MD; Digre, Kathleen B. MD

doi : 10.1097/WNO.0000000000001758

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A Great Conversation With Kathleen Digre.

Seay, Meagan D. DO; Calix, Rachel A. MD; Digre, Kathleen B. MD

doi : 10.1097/WNO.0000000000001810

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Biopsy of the Parietal Branch of the Superficial Temporal Artery for the Diagnosis of Giant Cell Arteritis.

Elahi, Ebby MD, MBA, FACS; Afshin, Evan E. MD; Zoltan, Susan MD, FACS; Hu, Karen Y. MD

doi : 10.1097/WNO.0000000000001631

Biopsy of the superficial temporal artery (STA) is central to the diagnosis of giant cell arteritis (GCA), but determining the ideal biopsy site along the course of the STA continues to be a challenge.

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Ocular Myasthenia Gravis 32 years From Remission to Relapse.

Kharsa, Ahmad BS; Raviskanthan, Subahari MBBS; Mortensen, Peter W. MD; Lee, Andrew G. MD

doi : 10.1097/WNO.0000000000001355

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Lambert[FIGURE DASH]Eaton Myasthenia Syndrome Initial Presentation Mimicking Myasthenia Gravis.

Uhm, So Yeon BS; Nguyen, Huy MD; Kanakia, Kunal P. MD; Carter, John E. MD

doi : 10.1097/WNO.0000000000001361

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Internal Carotid Artery Pseudoaneurysm Causing an Abducens Nerve Palsy: A Case Report.

Himstead, Alexander S. BS; Gustafson, Kevin M. MD; Hasso, Anton N. MD; Ediriwickrema, Lilangi S. MD

doi : 10.1097/WNO.0000000000001387

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Bilateral Tonic Pupils Due to Antidisialoganglioside Antibody Immunotherapy for Neuroblastoma.

Swiston, Cole MD; Jebaraj, Abigail MD; Vegunta, Sravanthi MD; Warner, Judith MD

doi : 10.1097/WNO.0000000000001414

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Three-Dimensional Printed Brain Model of a Patient With Alexia Without Agraphia Syndrome.

Pascoe, Alexis R. MD; Raviskanthan, Subahari MBBS; Mortensen, Peter W. MD; Lee, Andrew G. MD

doi : 10.1097/WNO.0000000000001600

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Convergence-Retraction Nystagmus and Ophthalmoplegia as the Presenting Sign of Leigh Syndrome in a Young Boy.

Chen, Weimin MD; Feny, Chaoyi MD, PhD; Chu, Shuguang MD, PhD; Zhao, Guixian MD, PhD; Sun, Xinghuai MD, PhD; Li, Zhenxin MD, PhD; Chen, Qian MD, PhD; Tian, Guohong MD, PhD

doi : 10.1097/WNO.0000000000001730

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Jesse Halpern, MD (1932-2022).

Forman, Scott MD

doi : 10.1097/WNO.0000000000001837

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The 59th Annual International Society for Clinical Electrophysiology of Vision Meeting in Liverpool, United Kingdom.

Seay, Meagan D. DO

doi : 10.1097/WNO.0000000000001745

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American Headache Society Meeting Scottsdale Arizona November 17-20, 2022.

Digre, Kathleen B. MD

doi : 10.1097/WNO.0000000000001802

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Blurred Disc Margins.

Britton, John O. T. BMBS; Yu-Wai-Man, Patrick PhD, FRCPath, FRCOphth; Chen, Benson S. MBChB, FRACP

doi : 10.1097/WNO.0000000000001842

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Eye Swelling and Decreased Vision in a Patient With Autism.

Xu, Jia MD; Zhang, Yanjia Jason MD; Gonzalez, Efren MD; Dohlman, Thomas H. MD; Gaier, Eric D. MD, PhD

doi : 10.1097/WNO.0000000000001832

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Movie-Like Palinopsia.

McDonald, Heather M. MD; Bursztyn, Lulu L. C. D. MD, FRCSC; Alexander Fraser, J. MD, FRCPC

doi : 10.1097/WNO.0000000000001808

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Socioeconomic Factors May Affect Diversity in Neuro-Ophthalmology.

Gluckstein, Jeffrey MD

doi : 10.1097/WNO.0000000000001495

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Reply to: Socioeconomic Factors May Affect Diversity in Neuro-Ophthalmology.

Quiros, Peter A. MD; Gordon, Lynn K. MD, PhD

doi : 10.1097/WNO.0000000000001496

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Headache, Confusion, and Hearing Loss: Erratum.

doi : 10.1097/WNO.0000000000001843

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A Diagnostic Conundrum of Bilateral Optic Disc Edema: Erratum.

doi : 10.1097/WNO.0000000000001844

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Vision Loss as a Presenting Feature of Chronic Inflammatory Demyelinating Polyneuropathy: A Case Series: Erratum.

doi : 10.1097/WNO.0000000000001833

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