Journal of Investigative Dermatology




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Editorial Board

doi : 10.1016/S0022-202X(23)01998-X

Volume 143, Issue 6, June 2023, Page A1

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Subscription Information

doi : 10.1016/S0022-202X(23)01999-1

Volume 143, Issue 6, June 2023, Page A2

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Table of Contents

doi : 10.1016/S0022-202X(23)02000-6

Volume 143, Issue 6, June 2023, Pages A3-A6

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Clinical Snippets

doi : 10.1016/j.jid.2023.04.001

Volume 143, Issue 6, June 2023, Page 879

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Editors’ Picks

doi : 10.1016/j.jid.2023.04.002

Volume 143, Issue 6, June 2023, Page 880

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TNF-α Blockade Inhibits Matrix Metalloproteinase 9–Mediated Collagenase Activity in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Chun-Bing Chen 1,2,3,4,5,6,7,8,9,10,11 , Chuang-Wei Wang 1,2,3,4,5 and Wen-Hung Chung

doi : 10.1016/j.jid.2023.03.1652

Volume 143, Issue 6, June 2023, Pages 881-883

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Lower Skin Cancer Risk in Vitiligo: DNA Repair as Potential Mechanism?

Rosalie M. Luiten

doi : 10.1016/j.jid.2023.01.018

Volume 143, Issue 6, June 2023, Pages 884-885

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2023 Marks the First International Societies for Investigative Dermatology Meeting in Tokyo

Russell P. Hall III 1 and Kenji Kabashima

doi : 10.1016/j.jid.2023.02.029

Volume 143, Issue 6, June 2023, Pages 886-887

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Mouse Models of Allergic Contact Dermatitis: Practical Aspects

Agatha Schwarz1 , Rebecca Philippsen1 and Thomas Schwarz

doi : 10.1016/j.jid.2023.03.1668

Volume 143, Issue 6, June 2023, Pages 888-892

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Therapeutic Application of Cell Secretomes in Cutaneous Wound Healing

Daniel Bormann1 , Alfred Gugerell1 , Hendrik Jan Ankersmit1,3 and Michael Mildner

doi : 10.1016/j.jid.2023.02.019

Volume 143, Issue 6, June 2023, Pages 893-912

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The Critical Role of Galectin-12 in Modulating Lipid Metabolism in Sebaceous Glands

Ching-Han Tsao1,2,9 , Wei-Chen Hsieh1,9 , Feng-Jen Lin1,3 , Ri-Yao Yang 4 , Meng-Ting Chang5 , Maria Karmella Apaya5 , Lie-Fen Shyur5 , Liang-Yin Ke2,6 , Christos C. Zouboulis7 and Fu-Tong Liu

doi : 10.1016/j.jid.2022.11.012

Volume 143, Issue 6, June 2023, Pages 913-924.e4

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Skin IL-17A and IFN-γ Production Correlate with Disease Severity in Patients with Psoriasis and Streptococcal Infection

Chiara Della Bella 1,2 , Alberto Corra` 3 , Elisabetta Mantengoli4 , Angelo Galano5 , Marisa Benagiano1 , Diletta Bonciani6 , Elena Biancamaria Mariotti3 , Sara Pratesi1 , Lavinia Quintarelli7 , Cristina Aimo3 , Alessia Grassi 1 , Sofia D’Elios8 , Walter Volpi7 , Alice Verdelli7 , Alessandro Bartoloni4 , Gian Maria Rossolini1,5 , Mario Milco D’Elios1,2 and Marzia Caproni

doi : 10.1016/j.jid.2022.10.025

Volume 143, Issue 6, June 2023, Pages 925-932

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Altered RNA Editing in Atopic Dermatitis Highlights the Role of Double-Stranded RNA for Immune Surveillance

Miriam Karmon1 , Eli Kopel1 , Aviv Barzilai 2,3 , Polina Geva 2 , Eli Eisenberg4 , Erez Y. Levanon 1,5 and Shoshana Greenberger

doi : 10.1016/j.jid.2022.11.010

Volume 143, Issue 6, June 2023, Pages 933-943.e8

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All-Cause and Cause-Specific Mortality Risks among Patients with Hidradenitis Suppurativa: A Korean Nationwide Population-Based Cohort Study

Solam Lee1,2 , Ju Yeong Lee1 , Ju Hee Han3 , Hyun Jeong Ju4 , Sung Ha Lim 1 , Jung Min Bae3 and Ji Hae Lee

doi : 10.1016/j.jid.2022.11.019

Volume 143, Issue 6, June 2023, Pages 944-953.e8

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Inhibition of Serum- and Glucocorticoid-Regulated Protein Kinase-1 Aggravates Imiquimod-Induced Psoriatic Dermatitis and Enhances Proinflammatory Cytokine Expression through the NF-kB Pathway

Qinqin Meng1,2,5 , Mei Bai 2,5 , Meiliang Guo2,5 , Zhengxiao Li 1 , Wanwen Liu2 , Xiaojing Fan2 , Rui Sun2 , Xinrong Yang2 , Dingfen Yuan2 , Yuling Shi 3,4 and Hui Deng

doi : 10.1016/j.jid.2022.12.013

Volume 143, Issue 6, June 2023, Pages 954-964

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Cancer-Associated Fibroblasts Exert Proangiogenic Activity in Merkel Cell Carcinoma

Silvia Albertini1,2 , Licia Martuscelli2 , Cinzia Borgogna2 , Sanamjeet Virdi3 , Daniela Indenbirken3 , Irene Lo Cigno2 , Gloria Griffante2 , Federica Calati 2 , Renzo Boldorini4 , Nicole Fischer1,5 and Marisa Gariglio

doi : 10.1016/j.jid.2022.12.006

Volume 143, Issue 6, June 2023, Pages 965-976.e15

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NPTX2 Promotes Epithelial–Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL

Tong Kang1,4 , Cheng Zhang2,4 , Hao Lei1 , Ruiting Luo1 , Meng Liu 1 , Shengbang Wang1 , Xiu Zhang1 , Qiqi Duan1 , Shengxiang Xiao3 and Yan Zheng

doi : 10.1016/j.jid.2022.12.015

Volume 143, Issue 6, June 2023, Pages 977-988.e2

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A Positive Loop Formed by SOX11 and Periostin Upregulates TGF-β Signals Leading to Skin Fibrosis

Yasuhiro Nanri1 , Satoshi Nunomura1 , Yuko Honda1 , Hironobu Takedomi2 , Yukie Yamaguchi3 and Kenji Izuhara

doi : 10.1016/j.jid.2022.12.008

Volume 143, Issue 6, June 2023, Pages 989-998.e7

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The Long Noncoding RNA LINC00958 Is Induced in Psoriasis Epidermis and Modulates Epidermal Proliferation

Longlong Luo1,2,3 , Lorenzo Pasquali1,2 , Ankit Srivastava 1,2,4,5 , Jan C. Freisenhausen1,2,3 , Andor Pivarcsi1,2,6 and Eniko ̈ Sonkoly

doi : 10.1016/j.jid.2022.12.011

Volume 143, Issue 6, June 2023, Pages 999-1010

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Tolerance to 2,4-Dinitrofluorobenzene‒Induced Contact Hypersensitivity Is Mediated by CD73-Expressing Tissue-Homing Regulatory T Cells

Meihong Da, Luxia Chen, Alexander Enk and Karsten Mahnke

doi : 10.1016/j.jid.2022.12.003

Volume 143, Issue 6, June 2023, Pages 1011-1022.e8

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TNF-α‒Mediated Keratinocyte Expression and Release of Matrix Metalloproteinase 9: Putative Mechanism of Pathogenesis in Stevens‒Johnson Syndrome/Toxic Epidermal Necrolysis

Anna Olsson-Brown 1 , Vincent Yip1 , Emeka D. Ogiji1 , Carol Jolly 1 , Lorenzo Ressel2 , Anurag Sharma3 , Wilma Bergfeld3 , Xuan Liu4 , Nitin Khirwadkar5 , Teresa Bellon6 , Anne Dickinson7 , Shaheda Ahmed 7 , Abigail Langton8 , Rachel Watson8 , Munir Pirmohamed1 and Daniel F. Carr

doi : 10.1016/j.jid.2022.11.024

Volume 143, Issue 6, June 2023, Pages 1023-1030.e7

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CD8+ T Cells Trigger Auricular Dermatitis and Blepharitis in Mice after Zika Virus Infection in the Absence of CD4+ T Cells

Cheryl Yi-Pin Lee 1,2,11 , Guillaume Carissimo1,3,11,12 , Teck-Hui Teo1 , Samuel Jia Ming Tong1 , Zi Wei Chang1 , Ravisankar Rajarethinam4 , Tze Kwang Chua5 , Zheyuan Chen5 , Rhonda Sin-Ling Chee1,2 , Alicia Tay5 , Shanshan Wu Howland5 , Kok Siong Ang5 , Jinmiao Chen 5 , Laurent Renia1,6,7 and Lisa F.P. Ng

doi : 10.1016/j.jid.2022.11.020

Volume 143, Issue 6, June 2023, Pages 1031-1041.e8

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PTPN11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Predisposes to Melanoma

Satyamaanasa Polubothu1,2,3 , Nicole Bender4,22 , Siobhan Muthiah5,22 , Davide Zecchin1,3 , Charalambos Demetriou1 , Sara Barberan Martin1,3 , Sony Malhotra 6 , Jana Travnickova7 , Zhiqiang Zeng7 , Markus Bo ̈ hm8 , Sebastien Barbarot9 , Catherine Cottrell 10 , Olivia Davies4 , Eulalia Baselga11 , Nigel P. Burrows12 , Virginie Carmignac13 , Joey Santiago Diaz14,15,16 , Christine Fink 17 , Holger A. Haenssle17 , Rudolf Happle18 , Mark Harland14 , Jacquelyn Majerowski4 , Pierre Vabres 13,19 , Marie Vincent9 , Julia A. Newton-Bishop 20 , D. Tim Bishop 20 , Dawn Siegel4 , E. Elizabeth Patton7 , Maya Topf21 , Neil Rajan5,23 , Beth Drolet4,23 and Veronica A. Kinsler

doi : 10.1016/j.jid.2022.09.661

Volume 143, Issue 6, June 2023, Pages 1042-1051.e3

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Involucrin Modulates Vitamin D Receptor Activity in the Epidermis

Alina D. Schmidt1,2,3 , Charlene Miciano1,2,3 , Qi Zheng4 , Mary Elizabeth Mathyer1,2,3 , Elizabeth A. Grice4 and Cristina de Guzman Strong

doi : 10.1016/j.jid.2022.12.009

Volume 143, Issue 6, June 2023, Pages 1052-1061.e3

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Genetic Variants in Telomerase Reverse Transcriptase Contribute to Solar Lentigines

Qianqian Peng1,14 , Yu Liu 1,14 , Anke Huels2,3 , Canfeng Zhang4 , Yao Yu 1,5 , Wenqing Qiu6 , Xiyang Cai 1 , Yuepu Zhao 1 , Tamara Schikowski2 , Katja Merches 2 , Yun Liu6 , Yajun Yang7,8 , Jiucun Wang7,8 , Yong Zhao9 , Li Jin7,8 , Liang Zhang5,10,11 , Jean Krutmann2,7,12,14 and Sijia Wang

doi : 10.1016/j.jid.2022.11.016

Volume 143, Issue 6, June 2023, Pages 1062-1072.e25

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FGF4 Promotes Skin Wound Repair through p38 MAPK and GSK3β-Mediated Stabilization of Slug

Jian Sun1,5 , Jie Zhou 1,5 , Jianhui Zhou2,5 , Wenxin Xu 1 , Yali Du 1 , Zhenyu Jia1 , Yingjie Shen1,3 , Xiaohua Lin4 , Xulan Wang1 , Yuxuan Bao1 , Zhiheng Rao1 , Siyang Dong1,4 , Yongde Luo1,4 , Weitao Cong 1 , Litai Jin1 and Xiaokun Li

doi : 10.1016/j.jid.2022.11.015

Volume 143, Issue 6, June 2023, Pages 1073-1084.e8

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Skin Barrier Function and Cognition among Older Adults

Richard W. Kim 1 , Yang An 2 , Linda Zukley 3 , Luigi Ferrucci 3 , Theodora Mauro 4,5 , Kristine Yaffe 6,7,8 , Susan M. Resnick 2 and Katrina Abuabara

doi : 10.1016/j.jid.2022.11.023

Volume 143, Issue 6, June 2023, Pages 1085-1087

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DKK3 Promotes Oxidative Stress‒Induced Fibroblast Activity

Sabrina Muecklich1,8 , Khuram Shehzad2,8 , Jessica Tiemann3,8 , Li Li4 , Sonja Leson 3 , Peter J. Nelson 2 , Richard Jennemann5 , Matthias Klein 6 , Christian Becker 3,7 , Roger Sandhoff 4 , Kerstin Steinbrink 3,7,8 and Verena K. Raker

doi : 10.1016/j.jid.2022.12.004

Volume 143, Issue 6, June 2023, Pages 1088-1090.e2

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The Relationship of Depression and Systemic Inflammation in Psoriasis: Findings from the UK Biobank

Georgia Lada1,2,* , Hector Chinoy3 , Peter S. Talbot2,4 , Richard B. Warren 1 and C. Elise Kleyn

doi : 10.1016/j.jid.2022.11.021

Volume 143, Issue 6, June 2023, Pages 1091-1094.e2

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Mucosal-Associated Invariant T Cells Are Altered in Patients with Hidradenitis Suppurativa and Contribute to the Inflammatory Milieu

Catriona Gallagher1,7 , Julie Mac Mahon1,7 , Chloe O’Neill2,7 , Fe �aron C. Cassidy 2 , Hazel Dunbar2 , Conor De Barra 2 , Caoimhe Cadden2 , Marta M. Pisarska2,3 , Nicole A.W. Wood2,3 , Joanne C. Masterson2 , Eoin N. McNamee2 , Elisabeth Schrumpf4,5 , Karen English2 , Donal O’Shea 5 , Anne Marie Tobin1,8 and Andrew E. Hogan

doi : 10.1016/j.jid.2022.11.011

Volume 143, Issue 6, June 2023, Pages 1094-1097.e2

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Possible Plasticity of Cytotoxic Resident Memory T Cells in Fixed Drug Eruption

Yutaka Matsumura1,2 , Rei Watanabe1,2,3,* , Hanako Koguchi- Yoshioka1,2 , Miki Kume2 , Shuichi Nakai2,3 , Junichi Furuta1 , Hiroaki Azukizawa 2 , Yosuke Ishitsuka 2,3 , Atsushi Tanemura2 , Mifue Taminato 4 , Hiroki Tashima4 , Naoya Otani4 , Koichi Tomita4 , Tateki Kubo 4 and Manabu Fujimoto

doi : 10.1016/j.jid.2022.11.022

Volume 143, Issue 6, June 2023, Pages 1097-1100.e8

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Placebo Response in Moderate-to-Severe Psoriasis: Prevalence Meta-Analysis of Randomized Controlled Trials

Sivem Afach1 , Laurence Le Cleach1,2 and Emilie Sbidian

doi : 10.1016/j.jid.2022.10.024

Volume 143, Issue 6, June 2023, Pages 1101-1104

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TRPA1 Mediates Contact Hypersensitivity Induced by 2,4-Dinitrochlorobenzene

Ilari Ma ̈ki-Opas 1,* , Mari Ha ̈ma ̈la ̈inen 1 , Lauri J. Moilanen 1 , Heini Sood 1 , Tiina Leppa ̈nen 1 , Laura Kummola2 , Ilkka S. Junttila3,4,5,6 , Lauri Lehtima ̈ki7,8 and Eeva Moilanen

doi : 10.1016/j.jid.2022.12.014

Volume 143, Issue 6, June 2023, Pages 1104-1108.e4

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Spatial Randomness in the Distribution of Acquired Melanocytic Nevi of the Back in a Population-Based Sample

Dilki Jayasinghe1 , Brigid Betz- Stablein2 , Mitchell S. Stark2 , H. Peter Soyer 2,3 and Monika Janda

doi : 10.1016/j.jid.2022.11.013

Volume 143, Issue 6, June 2023, Pages 1108-1111.e3

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Whole-Exome Sequencing of Vitiligo Lesions Indicates Lower Burden of Somatic Variations: Implications in Risk for Nonmelanoma Skin Cancers

Iti Gupta 1,2 , Shambhavi Shankrit 1 , Kiran Narta 1,2 , Madeeha Ghazi1,2 , Ritika Grover1,2 , Rajesh Pandey 1,2 , Hemanta Kumar Kar3,4 , Shruti Hit Count –Log 10P-value a c 4026 3822 4181 3774 4302 3903 4318 3971 3,500 3,600 3,700 3,800 3,900 4,000 4,100 4,200 4,300 4,400 L NL L NL L NL L NL VD19 VD22 VD33 VD39 Holoclone score b Figure 2. Transcriptomic footprint of the matched vitiligo skin implicates replication-coupled DNA repair. (a) Bubble plot depicting enriched processes from an upregulated set of genes on the basis of the whole-transcriptome sequencing of lesional compared with nonlesional vitiligo skin. (b) Volcano plot for genes pertaining to replication-coupled repair pathway. In this figure, the red dot represents a gene to be significantly upregulated in the lesional sample, whereas the green dot represents significant downregulation, on the basis of a P-value cutoff of 0.05 and a log2 fold change cutoff of 0.5. (c) Bar plot showing the holoclone score contribution in the lesional and nonlesional tissues. Holoclone score is the summation of normalized expression values for the holoclone signature genes across each sample. L denotes lesional, whereas NL denotes nonlesional. I Gupta et al. Vitiligo Skin Harbors Less Somatic Variations www.jidonline.org 1113 M. Menon 5 , Aayush Gupta 5 , Vamsi K. Yenamandra1,2 , Archana Singh1,2 , Mitali Mukerji 6 , Arijit Mukhopadhyay1,2,7 , Rajni Rani8 , Rajesh S. Gokhale1,8 , Debasis Dash1,2 and Vivek T. Natarajan

doi : 10.1016/j.jid.2022.11.018

Volume 143, Issue 6, June 2023, Pages 1111-1114.e8

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