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Investigating the Inverse Problem of Epileptogenic Zone Localization: Insights From Simultaneous EEG and SEEG.
McGonigal, Aileen MD, PhD
doi : 10.1212/WNL.0000000000207228
Volume 100(20) pgs. 937-987,e2045-e2092 May 16, 2023
Bridge to Arrest Infarct Growth: Win Time Through Faster Reperfusion.
Lin, Michelle P. MD, MPH; Anisetti, Bhrugun MBBS
Brain Shrinkage in Anti-[beta]-Amyloid Alzheimer Trials: Neurodegeneration or Pseudoatrophy?.
Barkhof, Frederik MD, PhD; Knopman, David S. MD
Intracerebral Correlates of Scalp EEG Ictal Discharges Based on Simultaneous Stereo-EEG Recordings.
Ferrand, Mickael MD; Baumann, Cedric MD; Aron, Olivier MD; Vignal, Jean-Pierre MD; Jonas, Jacques MD, PhD; Tyvaert, Louise MD, PhD; Colnat-Coulbois, Sophie MD, PhD; Koessler, Laurent PhD *; Maillard, Louis MD, PhD *
doi : 10.1212/WNL.0000000000207135
It remains unknown to what extent ictal scalp EEG can accurately predict the localization of the intracerebral seizure onset in presurgical evaluation of drug-resistant epilepsies.
Premature Mortality and Causes of Death Among People With Epilepsy: A Nationwide Population-Based Incident Cohort Study.
Moon, Hye-Jin MD, PhD; Lee, Hyesung PhD; Yoon, Dongwon PhD; Koo, Yong Seo MD, PhD; Shin, Ju-Young PhD; Lee, Seo-Young MD, PhD
doi : 10.1212/WNL.0000000000207212
People with epilepsy (PWE) are at risk of premature death with considerable variability according to the study population. We aimed to estimate the risk and causes of death in PWE according to age, disease severity, disease course, comorbidities, and socioeconomic status in Korea.
Association of Long-term Antiseizure Medication Use and Incident Type 2 Diabetes Mellitus.
Tseng, Wei-En Johnny MD; Chang, Chun-Wei MD; Hwang, Jawl-Shan MD; Ko, Po-Chuan MHSA; Liu, Chun-Jing MS; Lim, Siew-Na PhD
doi : 10.1212/WNL.0000000000207222
Diabetes mellitus (DM) contributes significantly to metabolic syndrome and cardiovascular events, and it may be a comorbidity of epilepsy. The objective of this study was to investigate whether long-term antiseizure medication (ASM) use is associated with the risk of developing type 2 diabetes. Methods: We analyzed data from the Chang Gung Research Database.
Effects of a Province-wide Triaging System for TIA: The ASPIRE Intervention.
Jeerakathil, Thomas J. MD, MSc, FRCPC; Yu, Amy Ying Xin MD, MSc; Choi, Philip M.C. MBChB; Fang, Shoufan PhD; Shuaib, Ashfaq MD; Majumdar, Sumit R. MD, MPH; Demchuk, Andrew M. MD, FRCPC; Butcher, Kenneth PhD; Watson, Tim J. MD; Dean, Naeem MBBS; Gordon, Deb MBA; Hill, Michael D. MD, MSc, FRCPC; Edmond, Cathy MBA; Coutts, Shelagh B. MD; for The ASPIRE Investigators
doi : 10.1212/WNL.0000000000207201
Urgent transient ischemic attack (TIA) management to reduce stroke recurrence is challenging, particularly in rural and remote areas. In Alberta, Canada, despite an organized stroke system, data from 1999 to 2000 suggested that stroke recurrence after TIA was as high as 9.5% at 90 days.
Association of Brain Age, Lesion Volume, and Functional Outcome in Patients With Stroke.
Liew, Sook-Lei PhD OTR/L; Schweighofer, Nicolas PhD; Cole, James H. PhD; Zavaliangos-Petropulu, Artemis PhD; Lo, Bethany P. BSc; Han, Laura K.M. PhD; Hahn, Tim PhD; Schmaal, Lianne PhD; Donnelly, Miranda R. MS; Jeong, Jessica N. BA; Wang, Zhizhuo MSc; Abdullah, Aisha BA; Kim, Jun H. BSc; Hutton, Alexandre MEng; Barisano, Giuseppe MD, PhD; Borich, Michael R. PhD; Boyd, Lara A. PhD; Brodtmann, Amy MBBS, PhD; Buetefisch, Cathrin M. MD, PhD; Byblow, Winston D. PhD
doi : 10.1212/WNL.0000000000207219
Functional outcomes after stroke are strongly related to focal injury measures. However, the role of global brain health is less clear. In this study, we examined the impact of brain age, a measure of neurobiological aging derived from whole-brain structural neuroimaging, on poststroke outcomes, with a focus on sensorimotor performance.
Accelerated Brain Volume Loss Caused by Anti-[beta]-Amyloid Drugs: A Systematic Review and Meta-analysis.
Alves, Francesca BBMED(Hons), PhD; Kalinowski, Pawel BBSc(Hons), MBiostat, PhD; Ayton, Scott PhD
doi : 10.1212/WNL.0000000000207156
To evaluate brain volume changes caused by different subclasses of anti-[beta]-amyloid (A[beta]) drugs trailed in patients with Alzheimer disease.
Association of Bone Mineral Density and Dementia: The Rotterdam Study.
Xiao, Tian MD *; Ghatan, Samuel MSc *; Mooldijk, Sanne S. MD; Trajanoska, Katerina MD, PhD; Oei, Ling MD, PhD; Gomez, M. Medina PhD; Ikram, M. Kamran MD, PhD; Rivadeneira, Fernando PhD; Ikram, M. Arfan MD, PhD
doi : 10.1212/WNL.0000000000207220
Low bone mineral density (BMD) and dementia commonly co-occur in older individuals, with bone loss accelerating in patients with dementia due to physical inactivity and poor nutrition. However, uncertainty persists over the extent to which bone loss already exists before onset of dementia.
Clinical Spectrum and Prognosis in Patients With Acute Nutritional Axonal Neuropathy.
Hamel, Johanna I. MD; Logigian, Eric L. MD
doi : 10.1212/WNL.0000000000207215
To describe the clinical, micronutrient, and electrophysiologic spectra and prognosis in patients with acute nutritional axonal neuropathy (ANAN).
Neurologic Care of Forcibly Displaced Persons: Emerging Issues in Neurology.
Mateen, Farrah J. MD, PhD; Hanafi, Ibrahem MD, MSc; Birbeck, Gretchen L. MD, MPH, DTMH; Saadi, Altaf MD, MSc; Schmutzhard, Erich MD, PhD; Wilmshurst, Jo M. MB, BS, MRCPaed, FCPaed, MD; Silsbee, Heather; Jones, Lyell K. Jr MD; on behalf of the AAN Quality Committee
doi : 10.1212/WNL.0000000000206857
AB There is a growing number of forcibly displaced persons (FDPs) worldwide. With more than 100 million people forcibly displaced today, there is an urgent mandate to understand the neurologic care needs of this population and how neurologists and other health care workers can most effectively provide that care.
What Are the Roles of Pericytes in the Neurovascular Unit and Its Disorders?.
Benarroch, Eduardo MD
Clinical Reasoning: A 47-Year-Old Man With an Upper Respiratory Infection, Acute Confusion, Dysarthria, and Ataxia.
Kubicki, Konrad MD, MA; Vargas, Alejandro MD, MS; O'Dwyer, Rebecca MD
doi : 10.1212/WNL.0000000000206864
AB A patient presenting with acute confusion, dysarthria, and appendicular ataxia with gait instability warrants a broad differential including emergent consideration of acute ischemic or hemorrhagic stroke.
Teaching NeuroImage: Nevus Flammeus, Ocular Melanosis, and Seizures in Young Adult With Sturge-Weber and Klippel-Trenaunay Overlap Syndrome.
Lavanya, Kunkala MD; Ramesh, Rithvik MD, DM; Shanmugam, Sundar MD, DM; Avadhani, Deepa MD, DM; Hazeena, Philo MD, DM
Editors' Note: Incidence of Epilepsy and Seizures Over the First 6 Months After a COVID-19 Diagnosis: A Retrospective Cohort Study.
Lewis, Ariane MD; Galetta, Steven MD
Reader Response: Incidence of Epilepsy and Seizures Over the First 6 Months After a COVID-19 Diagnosis: A Retrospective Cohort Study.
Brenner, Steven
Reader Response: Incidence of Epilepsy and Seizures Over the First 6 Months After a COVID-19 Diagnosis: A Retrospective Cohort Study.
Lin, Wei-Hao; Huang, Jing-Yang; Cheng-Chung Wei, James
PARK2, PINK1, and DJ1 in Patients With Early-Onset Parkinson's Disease in Four European Countries.
Bridging Thrombolysis Before Endovascular Therapy in Stroke Patients With Faster Core Growth.
Lin, Longting PhD; Zhang, Hao MD; Liu, Feifeng MD; Chen, Chen MD; Chen, Chushuang PhD; Bivard, Andrew PhD; Parsons, Mark W. PhD *; Li, Gang MD, PhD *; for INSPIRE; for INSPIRE; Levi, Christopher R. MD; Spratt, Neil J. MD; Garcia-Esperon, Carlos MD, PhD; Miteff, Ferdinand MD; Choi, Philip M.C. MD; Kleining, Timothy MD, PhD; O'Brien, Billy MD; Butcher, Kenneth MD, PhD; Yang, Jianhong MD; Yin, Congguo MD; Wang, Peng MD; Geng, Yu MD; Fang, Qi MD; Sui, Yi MD, PhD; Chen, Wenhuo MD; Cheng, Xin MD; Dong, Qiang MD
doi : 10.1212/WNL.0000000000207154
It is still uncertain that going direct to endovascular thrombectomy (EVT) leads to equivalent outcomes as bridging IV thrombolysis (IVT) in acute ischemic patients.
