Rheumatology




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Is the parent global assessment a reliable quality of life measure in juvenile idiopathic arthritis?

Giovanni Filocamo, Alessandro Consolaro, Angelo Ravelli

doi : 10.1093/rheumatology/keac600

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2023–2024

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How to manage patients perceived as having a mild form of early arthritis?

Diederik De Cock, Sofia Ajeganova, Patrick Verschueren

doi : 10.1093/rheumatology/keac657

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2025–2026

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Good common sense and clinical judgment should be the driver for further investigation

Soumya Chatterjee

doi : 10.1093/rheumatology/keac631

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2027–2029

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Clinical observation: are nightmares a manifestation of neuropsychiatric lupus?

David P D’Cruz, Melanie Sloan

doi : 10.1093/rheumatology/keac655

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2030–2031

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The pre-clinical phase of giant cell arteritis: new clues in the pathogenesis of giant cell arteritis supporting emerging targets

Luca Quartuccio, Elena Treppo, Christian Dejaco

doi : 10.1093/rheumatology/keac697

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2032–2034,

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Depression in spondyloarthritis: can we kill two birds with one stone?

Konstantina Magiouf, George E Fragoulis

doi : 10.1093/rheumatology/keac704

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2035–2036

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A systematic review of the sex differences in risk factors for knee osteoarthritis

Ingrid A Szilagyi, Jan H Waarsing, Joyce B J van Meurs, Sita M A Bierma-Zeinstra, Dieuwke Schiphof

doi : 10.1093/rheumatology/keac688

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2037–2047

Previous systematic reviews focused on the evidence of common risk factors for knee OA (KOA); however, the effect and strength of association between risk factors and KOA might be different between the two sexes. The aim of the present systematic review was to determine the current evidence on sex differences in the association between risk factors and KOA and their prevalence.

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Multibiomarker disease activity score: an objective tool for monitoring rheumatoid arthritis? A systematic review and meta-analysis

Fanni A Meznerics, Lajos V Kemény, Emese Gunther, Eszter Bakó, Fanni Dembrovszky, Bence Szabó, Anna Ascsillán, Elmar Lutz, Dezsö Csupor, Péter Hegyi, András Bánvölgyi, György Nagy

doi : 10.1093/rheumatology/keac715

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2048–2059

The multibiomarker disease activity (MBDA) score is an objective tool for monitoring disease activity in RA. Here we report a systematic review and meta-analysis of the clinical value of the MBDA score in RA.

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Improving outcomes in scleroderma: recent progress of cell-based therapies

Dinesh Khanna, Nancy Krieger, Keith M Sullivan

doi : 10.1093/rheumatology/keac628

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2060–2069

Scleroderma is a rare, potentially fatal, clinically heterogeneous, systemic autoimmune connective tissue disorder that is characterized by progressive fibrosis of the skin and visceral organs, vasculopathy and immune dysregulation. The more severe form of the disease, diffuse cutaneous scleroderma (dcSSc), has no cure and limited treatment options.

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Thrombocytopaenia in antiphospholipid syndrome: a free radical perspective

Paul R J Ames, Tommaso Bucci, Mira Merashli, Alessia Arcaro, Fabrizio Gentile

doi : 10.1093/rheumatology/keac650

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2070–2075

Thrombosis associated with thrombocytopaenia is an apparent paradox that is present across a wide spectrum of disorders.

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Comparison of health-care utilization, costs and health-related quality of life across the subgroups defined by the Keele STarT MSK Tool

Raymond Oppong, Martyn Lewis, Paul Campbell, Kate M Dunn, Nadine E Foster, Jonathan C Hill, Sue Jowett

doi : 10.1093/rheumatology/keac560

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2076–2082

The aim of this study was to describe and compare health economic outcomes [health-care utilization and costs, work outcomes, and health-related quality of life (EQ-5D-5L)] in patients classified into different levels-of-risk subgroups by the Keele STarT MSK Tool.

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Early characterization of difficult-to-treat rheumatoid arthritis by suboptimal initial management: a multicentre cohort study

Alessandro Giollo, Margherita Zen, Maddalena Larosa, Davide Astorri, Mariangela Salvato, Antonia Calligaro, Konstantinos Botsios, Cristina Bernardi, Gerolamo Bianchi, Andrea Doria

doi : 10.1093/rheumatology/keac563

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2083–2089

To demonstrate that unsuccessful treatment optimization in early disease is associated with difficult-to-treat RA (D2T-RA).

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Non-trough adalimumab and certolizumab drug levels associated with a therapeutic EULAR response in adherent patients with rheumatoid arthritis

Ryan M Hum, Pauline Ho, Nisha Nair, Meghna Jani, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Darren Plant, Anne Barton, the BRAGGSS Collaborators

doi : 10.1093/rheumatology/keac564

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2090–2097

Interventions aimed at increasing TNF-α inhibitor serum drug levels (SDLs) may improve treatment response; however, previous studies suggesting SDL cut-offs have not accounted for treatment adherence. The aim of this study was to establish the relationship between adalimumab/certolizumab SDLs and EULAR good vs non-/moderate response and to define SDL cut-offs associated with good response in fully adherent patients.

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Favourable effect of a ‘second hit’ after 13 weeks in early RA non-responders: the Amsterdam COBRA treat-to-target randomized trial

Linda Hartman, Linda A Rasch, Samina A Turk, Marieke M ter Wee, Pit J S M Kerstens, Conny J van der Laken, Michael T Nurmohamed, Dirkjan van Schaardenburg, Lilian H D van Tuyl, Alexandre E Voskuyl, Maarten Boers, Willem F Lems

doi : 10.1093/rheumatology/keac582

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2098–2105,

The aim of this study was to investigate the effect of treat-to-target combination therapy with intensification at 13 weeks in early RA.

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The association between autoantibodies and risk for venous thromboembolic events among patients with rheumatoid arthritis

Helga Westerlind, Alf Kastbom, Johan Rönnelid, Monika Hansson, Lars Alfredsson, Linda Mathsson-Alm, Guy Serre, Martin Cornillet, Rikard Holmdahl, Karl Skriner, Holger Bang, Lars Klareskog, Saedis Saevarsdottir, Karin Lundberg, Caroline Grönwall, Johan Askling

doi : 10.1093/rheumatology/keac601

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2106–2112

To assess the association between venous thromboembolic (VTE) events and autoantibodies, following patients from RA diagnosis, measuring occurrence, levels and collective load of different autoantibodies against post-translational protein modifications, in particular recognizing citrullination (e.g. citrullinated fibrinogen) and RF by isotype.

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Efficacy and safety of risankizumab for active psoriatic arthritis: 52-week results from the KEEPsAKE 1 study

Lars Erik Kristensen, Mauro Keiserman, Kim Papp, Leslie McCasland, Douglas White, Wenjing Lu, Ahmed M Soliman, Ann Eldred, Lisa Barcomb, Frank Behrens

doi : 10.1093/rheumatology/keac607

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2113–2121

PsA is a chronic disease with heterogeneous clinical manifestations requiring treatment options with long-term efficacy and safety. In this follow-up analysis, the 52-week efficacy and safety of risankizumab 150 mg in patients with active PsA who had previous inadequate response/intolerance to one or more conventional synthetic DMARDs (csDMARD-IR) were evaluated.

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Efficacy and safety of risankizumab for active psoriatic arthritis: 52-week results from the KEEPsAKE 2 study

Andrew Östör, Filip Van den Bosch, Kim Papp, Cecilia Asnal, Ricardo Blanco, Jacob Aelion, Wenjing Lu, Zailong Wang, Ahmed M Soliman, Ann Eldred, Byron Padilla, Alan Kivitz

doi : 10.1093/rheumatology/keac605

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2122–2129

PsA is a chronic inflammatory disease in which the skin and joints are affected. In this follow-up analysis, the 52-week efficacy and safety of risankizumab 150 mg in patients with active PsA who had previous inadequate response/intolerance to one or two biologic therapies (Bio-IR) or one or more conventional synthetic DMARDs (csDMARD-IR) were evaluated.

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Performance of an MRI scoring system for inflammation of joints and entheses in peripheral SpA: post-hoc analysis of the CRESPA trial

Simon Krabbe, Thomas Renson, Lennart Jans, Dirk Elewaut, Filip Van den Bosch, Philippe Carron, Mikkel Østergaard

doi : 10.1093/rheumatology/keac567

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2130–2138

The aim of this study was to investigate the reliability, validity, and sensitivity to change of a novel MRI scoring system in early peripheral SpA (pSpA).

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The effect of anti-inflammatory treatment on depressive symptoms in spondyloarthritis: does the type of drug matter?

Casper Webers, Uta Kiltz, Jürgen Braun, Désirée van der Heijde, Annelies Boonen

doi : 10.1093/rheumatology/keac580

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2139–2146

To investigate the effect of pharmacological treatment of SpA on depressive symptoms and explore whether this effect differs between drug classes.

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Trust in the attending rheumatologist, health-related hope and medication adherence among Japanese systemic lupus erythematosus patients

Noriaki Kurita, Nao Oguro, Yoshia Miyawaki, Chiharu Hidekawa, Natsuki Sakurai, Takanori Ichikawa, Yuichi Ishikawa, Keigo Hayashi, Kenta Shidahara, Dai Kishida, Ryusuke Yoshimi, Ken-ei Sada, Yasuhiro Shimojima, Nobuyuki Yajima

doi : 10.1093/rheumatology/keac565

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2147–2153

Poor medication adherence among patients with SLE is a critical problem associated with adverse outcomes. This study examined the relationship between trust in one’s physician and goal-oriented thinking, hope and medication adherence among Japanese patients with SLE who were ethnically matched to their physicians.

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Grit personality of physicians and achievement of treatment goals in patients with system lupus erythematosus

Ken-ei Sada, Yoshia Miyawaki, Kenta Shidahara, Shoichi Nawachi, Yu Katayama, Yosuke Asano, Keigo Hayashi, Keiji Ohashi, Eri Katsuyama, Takayuki Katsuyama, Mariko Takano-Narazaki, Yoshinori Matsumoto, Nao Oguro, Yuichi Ishikawa, Natsuki Sakurai, Chiharu Hidekawa, Ryusuke Yoshimi, Dai Kishida, Takanori Ichikawa, Yasuhiro Shimojima, Noriaki Kurita, Nobuyuki Yajima

doi : 10.1093/rheumatology/keac612

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2154–2159

Although personality characteristics of patients with SLE affect their disease activity and damage, it is unclear whether those of attending physicians affect the outcomes of patients with SLE. Grit is a personality trait for achieving long-term goals that may influence the decision-making for continuing treatment plans for patients. We aimed to evaluate the relationship between the grit of attending physicians and achievement of treatment goals in patients with SLE.

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‘I turned in my man card’: a qualitative study of the experiences, coping styles and support needs of men with systemic sclerosis

Caroline A Flurey, John D Pauling, Lesley Ann Saketkoo, Christopher P Denton, Paul Galdas, Dinesh Khanna, Adrian Williams, Michael Hughes

doi : 10.1093/rheumatology/keac585

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2160–2167

Men with SSc have a more severe clinical phenotype and reduced survival compared with women. No previous psychosocial studies have focused solely on men with SSc. This study aimed to explore experiences, coping strategies and support preferences of men with SSc.

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Functional autoantibodies in systemic sclerosis: influence of autologous stem cell transplantation and correlation with clinical outcome

Lukas Bankamp, Beate Preuß, Ann-Christin Pecher, Wichard Vogel, Jörg Henes, Reinhild Klein

doi : 10.1093/rheumatology/keac549

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2168–2177

To evaluate the effect of autologous stem cell transplantation (aSCT) on functional antibodies (abs) to the angiotensin II type-1-receptor (AT1R) and topoisomerase-I (topo-I) in SSc-patients and to analyse their prognostic relevance.

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Systemic sclerosis-associated interstitial lung disease in the EUSTAR database: analysis by region

Alain Lescoat, Dörte Huscher, Nils Schoof, Paolo Airò, Jeska de Vries-Bouwstra, Gabriela Riemekasten, Eric Hachulla, Andrea Doria, Edoardo Rosato, Nicolas Hunzelmann, Carlomaurizio Montecucco, Armando Gabrielli, Anna-Maria Hoffmann-Vold, Oliver Distler, Jennifer Ben Shimol, Maurizio Cutolo, Yannick Allanore, the EUSTAR collaborators

doi : 10.1093/rheumatology/keac576

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2178–2188

The prevalence and characteristics of SSc-associated interstitial lung disease (SSc-ILD) vary between geographical regions worldwide. The objectives of this study were to explore the differences in terms of prevalence, phenotype, treatment and prognosis in patients with SSc-ILD from predetermined geographical regions in the EUSTAR database.

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Cutaneous vasculitis occurring in the setting of systemic lupus erythematosus: a multicentre cohort study

Paul Breillat, Marie Jachiet, Yoan Ditchi, Cédric Lenormand, Nathalie Costedoat-Chalumeau, Alexis Mathian, Philippe Moguelet, Paul Duriez, Marten Trendelenburg, Uyen Huynh-Do, Carlo Chizzolini, Clément Beuvon, Frederique Roy-Peaud, Jean-David Bouaziz, Annick Barbaud, Camille Francès, Arsène Mékinian, Olivier Fain, Zahir Amoura, François Chasset, for EMSED study group (Etude des maladies systémiques en dermatologie) and the Swiss SLE Cohort Study (SSCS)

doi : 10.1093/rheumatology/keac566

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2189–2196

To describe the clinical and pathological features of biopsy-proven cutaneous vasculitis (CV) associated with SLE, focusing on diagnosis classification and impact on overall SLE activity.

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Added diagnostic yield of temporal artery magnetic resonance angiography in the evaluation of giant cell arteritis

Mats L Junek, Shaista Riaz, Stephanie Garner, Nader Khalidi, Ryan Rebello

doi : 10.1093/rheumatology/keac583

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2197–2202

Temporal artery magnetic resonance angiography (TAMRA) is a useful tool to investigate possible diagnoses of GCA. As acquired images also reveal other local structures, they may assist in finding alternative diagnoses when assessing for possible GCA. We sought to assess the utility of TAMRA in identifying other significant abnormalities either associated with a diagnosis of GCA or potentially mimicking a clinical presentation of GCA.

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Angiotensin receptor blockade is associated with increased risk of giant cell arteritis

Sizheng Steven Zhao, Houchen Lyu, Chao Zeng, Guanghua Lei, Jie Wei, Sarah L Mackie

doi : 10.1093/rheumatology/keac599

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2203–2210

Angiotensin II is implicated in GCA pathology. We examined whether the use of angiotensin receptor blockers (ARBs) is associated with GCA risk compared with angiotensin-converting enzyme inhibitors (ACEis) or other antihypertensives.

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The adjusted Global Anti-Phospholipid Syndrome Score as predictor of damage accrual measured by Damage Index for APS: a longitudinal study

Giuseppe Barilaro, Carlo Della Rocca, Alexandra Esteves, Ricard Cervera, Gerard Espinosa

doi : 10.1093/rheumatology/keac619

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2211–2219

To analyse the association between the average ‘adjusted’ Global APS Score (aGAPSS) over time, as a surrogate of disease activity, and change in Damage Index for APS (DIAPS) during follow-up in patients with thrombotic and non-thrombotic APS.

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Revisiting idiopathic eosinophilic myositis: towards a clinical-pathological continuum from the muscle to the fascia and skin

Cécile Fermon, Lola E R Lessard, Tanguy Fenouil, Alain Meyer, Marie Faruch-Bilfeld, Marie Robert, Verena Landel, Arnaud Hot, François-Jérôme Authier, Nathalie Streichenberger, Laure Gallay

doi : 10.1093/rheumatology/keac556

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2220–2229

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Biologics with or without methotrexate in treatment of polyarticular juvenile idiopathic arthritis: effectiveness, safety and drug survival

Franz Thiele, Ariane Klein, Jens Klotsche, Daniel Windschall, Frank Dressler, Jasmin Kuemmerle-Deschner, Kirsten Minden, Ivan Foeldvari, Dirk Foell, Sonja Mrusek, Prasad Thomas Oommen, Gerd Horneff

doi : 10.1093/rheumatology/keac587

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2230–2238

To investigate the impact of additionally given MTX on biologic treatment of polyarticular JIA in terms of effectiveness, safety and drug survival.

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Comprehensive and reliable sonographic assessment and scoring system for inflammatory lesions of the paediatric ankle

Patricia Vega-Fernandez, Deirdre De Ranieri, Edward Oberle, Matthew Clark, Hulya Bukulmez, Clara Lin, Susan Shenoi, Akaluck Thatayatikom, Leandra Woolnough, Heather Benham, Emily Brunner, Michael Henrickson, Laura R Pratt, Jean-Philippe Proulx-Gauthier, Ginger Janow, Amy Cassedy, Tracy V Ting, Johannes Roth for

doi : 10.1093/rheumatology/keac622

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2239–2246

The clinical decision-making process in paediatric arthritis lacks an objective, reliable bedside imaging tool. The aim of this study was to develop a US scanning protocol and assess the reliability of B-mode and Doppler scoring systems for inflammatory lesions of the paediatric ankle.

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Nationwide racial/ethnic disparities in US emergency department visits and hospitalizations for gout

Chio Yokose, Natalie McCormick, Na Lu, Amit D Joshi, Lesley Jackson, Minna J Kohler, Janeth Yinh, Yuqing Zhang, John Hsu, Nicola Dalbeth, Kenneth G Saag, Hyon K Choi

doi : 10.1093/rheumatology/keac590

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2247–2251

Gout prevalence is reportedly ∼20% higher in US Black adults than Whites, but racial differences in emergency department (ED) visits and hospitalizations for gout are unknown. We evaluated the latest US national utilization datasets according to racial/ethnic groups.

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Antiphospholipid antibody positivity in early systemic lupus erythematosus is associated with subsequent vascular events

Nicola Farina, Ruya Abdulsalam, Thomas McDonnell, Charis Pericleous, Amrita D’Souza, Vera M Ripoll, Jemma Webster, David A Isenberg, Ian Giles, Anisur Rahman

doi : 10.1093/rheumatology/keac596

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2252–2256

aPL are found in the blood of 20–30% of patients with SLE. Although aPL cause vascular thrombosis in the antiphospholipid syndrome, it is not clear whether positive aPL levels in early SLE increase risk of subsequent vascular events (VE).

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External validation of the alternative Ankylosing Spondylitis Disease Activity Score in three randomized clinical trials of ixekizumab

Augusta Ortolan, Sofia Ramiro, Roberta Ramonda, Désirée van der Heijde

doi : 10.1093/rheumatology/keac618

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2257–2261

The alternative ASDAS (altASDAS) is an index that can be used when patient global assessment is unavailable. Our aim was to test the truth and discrimination aspects according to OMERACT filter 2.0 of the altASDAS in an external cohort.

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Inactivated SARS-CoV-2 vaccine does not increase the risk of relapse in patients with clinically inactive adult-onset Still’s disease

Xinyue Hong, Haoyu Pan, Yutong Su, Qiongyi Hu, Yue Sun, Honglei Liu, Xiaobing Cheng, Junna Ye, Hui Shi, Jianfen Meng, Zhuochao Zhou, Jinchao Jia, Tingting Liu, Mengyan Wang, Xia Chen, Yuning Ma, Zihan Tang, Fan Wang, Hao Zhang, Yijun You, Dehao Zhu, Longfang Chen, Chengde Yang, Jialin Teng, Huihui Chi

doi : 10.1093/rheumatology/keac620

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2262–2266

A succession of cases have reported flares of adult-onset Still’s disease (AOSD) after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), raising concerns. We aimed to investigate the impact of inactivated SARS-CoV-2 vaccines on disease activity in patients with AOSD.

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Relevance of leukaemia inhibitory factor to anti-melanoma differentiation-associated gene 5 antibody-positive interstitial lung disease

Yuki Ichimura, Hiroyuki Ikei, Risa Konishi, Moko Zeniya, Takahiro Okai, Toshifumi Nomura, Kousuke Negishi, Naoko Okiyama

doi : 10.1093/rheumatology/keac632

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2267–2271

Anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive rapidly progressive interstitial lung disease (RP-ILD) is a life-threatening disease, the aetiology of which remains unclear. To detect potential diagnostic markers, a transcriptome analysis of the lung sample from a patient with anti-MDA5 antibody-positive RP-ILD was performed.

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Development of a scoring model for the Sharp/van der Heijde score using convolutional neural networks and its clinical application

Suguru Honda, Koichiro Yano, Eiichi Tanaka, Katsunori Ikari, Masayoshi Harigai

doi : 10.1093/rheumatology/keac586

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2272–2283

To construct a predictive model for the Sharp/van der Heijde score (SHS) and assess its applicability in clinical research settings.

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Autoimmune activation and hypersensitization of the AT1 and ETA receptors contributes to vascular injury in scleroderma renal crisis

Björn Hegner, Tobias Kretzschmar, Nan Zhu, Gunnar Kleinau, Hongfan Zhao, Julian Kamhieh-Milz, Julia Hilger, Ralf Schindler, Patrick Scheerer, Gabriela Riemekasten, Aurélie Philippe, Rusan Catar

doi : 10.1093/rheumatology/keac594

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2284–2293

Scleroderma renal crisis (SRC) is a rare vascular complication of systemic sclerosis with substantial risks for end-stage renal disease and premature death. Activating autoantibodies (Abs) targeting the angiotensin II type 1 (AT1R) and the endothelin-1 type A receptor (ETAR) have been identified as predictors for SRC.

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Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination

Leher Gumber, Nancy Gomez, Georgina Hopkins, Davis Tucis, Laura Bartlett, Kieran Ayling, Kavita Vedhara, Graham Steers, Mithun Chakravorty, Megan Rutter, Hannah Jackson, Patrick Tighe, Alastair Ferraro, Sheila Power, Marie-Josèphe Pradère, David Onion, Peter C Lanyon, Fiona A Pearce, Lucy Fairclough

doi : 10.1093/rheumatology/keac574

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2294–2303

Coronavirus 2019 vaccine responses in rare autoimmune rheumatic diseases (RAIRDs) remain poorly understood; in particular there is little known about whether people develop effective T cell responses.

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Analyses of plasma inflammatory proteins reveal biomarkers predictive of subsequent development of giant cell arteritis: a prospective study

Karin Wadström, Lennart T H Jacobsson, Aladdin J Mohammad, Kenneth J Warrington, Eric L Matteson, Magnus E Jakobsson, Carl Turesson

doi : 10.1093/rheumatology/keac581

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2304–2311

To investigate the relation between biomarkers of inflammation and subsequent development of GCA.

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Citrullinated and carbamylated proteins in extracellular microvesicles from plasma of patients with rheumatoid arthritis

Federica M Ucci, Serena Recalchi, Cristiana Barbati, Valeria Manganelli, Antonella Capozzi, Gloria Riitano, Giorgia Buoncuore, Tina Garofalo, Fulvia Ceccarelli, Francesca R Spinelli, Eugenia Balbinot, Alessandra Ida Celia, Agostina Longo, Cristiano Alessandri, Roberta Misasi, Maurizio Sorice, Fabrizio Conti

doi : 10.1093/rheumatology/keac598

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2312–2319

To investigate the expression of citrullinated and carbamylated proteins in extracellular microvesicles (EMVs) from RA patients.

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WDFY4 polymorphisms in Chinese patients with anti-MDA5 dermatomyositis is associated with rapid progressive interstitial lung disease

Li Guo, Xueliang Zhang, Weilin Pu, Jiangfeng Zhao, Kaiwen Wang, Danting Zhang, Soonmin Hong, Yanyun Ma, Xiaodong Wang, Shuang Ye, Qiang Guo, Jiucun Wang

doi : 10.1093/rheumatology/kead006

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2320–2324

Anti-melanoma differentiation-associated gene 5 antibody positive dermatomyositis (MDA5+DM), is susceptible to development of rapidly progressive interstitial lung disease (RPILD), which has been predominantly reported in East Asia.

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A deep learning system for quantitative assessment of microvascular abnormalities in nailfold capillary images

Praveen Gurunath Bharathi, Michael Berks, Graham Dinsdale, Andrea Murray, Joanne Manning, Sarah Wilkinson, Maurizio Cutolo, Vanessa Smith, Ariane L Herrick, Chris J Taylor

doi : 10.1093/rheumatology/kead026

Rheumatology, Volume 62, Issue 6, June 2023, Pages 2325–2329

Nailfold capillaroscopy is key to timely diagnosis of SSc, but is often not used in rheumatology clinics because the images are difficult to interpret. We aimed to develop and validate a fully automated image analysis system to fill this gap.

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Correction to: Continuing specialist care into adulthood in young people with juvenile idiopathic arthritis: a retrospective cohort study using electronic health records in England

doi : 10.1093/rheumatology/kead005

Rheumatology, Volume 62, Issue 6, June 2023, Page 2330

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Correction to: Clinical and biomechanical factors associated with falls and rheumatoid arthritis: baseline cohort with longitudinal nested case–control study

doi : 10.1093/rheumatology/kead043

Rheumatology, Volume 62, Issue 6, June 2023, Page 2331

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COVID-19 vaccine safety during the antenatal period in women with idiopathic inflammatory myopathies

Laura Andreoli, Parikshit Sen, Daniele Lini, Melinda Nagy Vincze, Karen Schreiber, Vikas Agarwal, Rohit Aggarwal, Latika Gupta, COVAD Study Group

doi : 10.1093/rheumatology/keac644

Rheumatology, Volume 62, Issue 6, June 2023, Pages e175–e179

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Utilization of electronic health record data to evaluate the association of urban environment with systemic lupus erythematosus symptoms

Janet Song, Noah Forrest, Adam Gordon, Leah Kottyan, Kathleen F Mittendorf, Wei-Qi Wei, Rosalind Ramsey-Goldman, Theresa Walunas, Abel Kho

doi : 10.1093/rheumatology/keac647

Rheumatology, Volume 62, Issue 6, June 2023, Pages e180–e181

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Association between disability scores and opioid use in patients with psoriatic arthritis and ankylosing spondylitis

Alexis Ogdie, Mark Hwang, Sofia Pedro, Phani Veeranki, Esther Yi, Steven Hass, Kaleb Michaud

doi : 10.1093/rheumatology/keac673

Rheumatology, Volume 62, Issue 6, June 2023, Pages e182–e184

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COVID-19 antiviral therapy for non-hospitalized immunosuppressed patients with rheumatic diseases is feasible with positive outcomes

Chung M A Lin, Josh Bennett, Lavanya Rajagopala, Ewan Hunter, Alice R Lorenzi, Bridget Griffiths, Kenneth F Baker

doi : 10.1093/rheumatology/keac705

Rheumatology, Volume 62, Issue 6, June 2023, Pages e185–e187

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Brain oedema due to disseminated intravascular coagulation in a patient with adult-onset Still’s disease–associated hemophagocytic lymphohistiocytosis—a case report

Georg Lorenz, Christian Schaaf, Philipp Moog, Quirin Bachmann, Florian Popp, Jürgen Rech, Johanna Schorr, Carmen Gabl, Claudius Küchle, Claire Delbridge, Gregor G Weirich, Uwe Heemann, Gerhard Schneider, Nicole Lange, Matias Wagner, Wiebke Berg-Johnson

doi : 10.1093/rheumatology/keac595

Rheumatology, Volume 62, Issue 6, June 2023, Pages e188–e190

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Immune checkpoint inhibitor-induced radiation recall myositis

Hirotaka Yamamoto, Yoshinori Taniguchi

doi : 10.1093/rheumatology/keac636

Rheumatology, Volume 62, Issue 6, June 2023, Pages e191–e192

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A case of A20 haploinsufficiency in which intestinal inflammation improved with thalidomide

Kanako Mitsunaga, Yuzaburo Inoue, Chie Naito, Hitoshi Ogata, Yoshinobu Itoh, Yoshiko Natsui, Takeshi Saito, Minako Tomiita

doi : 10.1093/rheumatology/keac634

Rheumatology, Volume 62, Issue 6, June 2023, Pages e193–e195

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A novel frameshift variant in TNFRSF13B in a Chinese patient with late-onset combined immunodeficiency

Junke Miao, Min Shen

doi : 10.1093/rheumatology/keac681

Rheumatology, Volume 62, Issue 6, June 2023, Pages e196–e198

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Comment on: Text neck misdiagnosed as fibromyalgia

Ney Meziat-Filho, Tatiana Grasser, Igor Correia, Felipe J J Reis

doi : 10.1093/rheumatology/keac642

Rheumatology, Volume 62, Issue 6, June 2023, Pages e199–e200

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Comment on: Text neck misdiagnosed as fibromyalgia. Reply

Taro Horino, Hiroshi Ohnishi, Masahiro Komori, Yoshio Terada

doi : 10.1093/rheumatology/keac643

Rheumatology, Volume 62, Issue 6, June 2023, Page e201

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Comment on: The association between autoantibodies and risk for venous thromboembolic events among patients with rheumatoid arthritis

Duygu Tecer, Muhammet Cinar, Sedat Yilmaz

doi : 10.1093/rheumatology/keac648

Rheumatology, Volume 62, Issue 6, June 2023, Pages e202–e203

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Comment on: The association between autoantibodies and risk for venous thromboembolic events among patients with rheumatoid arthritis: reply

Helga Westerlind, Alf Kastbom, Johan Askling

doi : 10.1093/rheumatology/keac649

Rheumatology, Volume 62, Issue 6, June 2023, Page e204

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Multicentric Castleman disease with trismus

Takuya Kakutani, Masaki Yoshizawa

doi : 10.1093/rheumatology/keac611

Rheumatology, Volume 62, Issue 6, June 2023, Pages e205–e206

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Bilateral sclerochoroidal calcification in a patient with calcium pyrophosphate deposition disease

Tuba Demirci Yildirim, Turhan Mammadov, Ali Osman Saatci, Ismail Sari

doi : 10.1093/rheumatology/keac633

Rheumatology, Volume 62, Issue 6, June 2023, Pages e207–e208

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Ixekizumab-associated disseminated tinea corporis in a patient with psoriatic arthritis and plaque psoriasis

Kamran Naraghi, Kave Shams, Helena Marzo-Ortega

doi : 10.1093/rheumatology/keac635

Rheumatology, Volume 62, Issue 6, June 2023, Pages e209–e210

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