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Application of the International League Against Epilepsy Neonatal Seizure Framework to an international panel of medical personnel
Elissa G. Yozawitz, Maria R. Cilio, Eli M. Mizrahi, Jee-Young Moon, Solomon L. Moshé, Magda L. Nunes, Perrine Plouin, Sampsa Vanhatalo, Sameer Zuberi, Ronit M. Pressler
doi : 10.1002/epd2.20005
The International League Against Epilepsy (ILAE) Neonatal Seizure Framework was tested by medical personnel.
Ictal blinking triggered by isolated spikes as the only manifestation of seizures
Roohi Katyal, Shirin Jamal-Omidi, Takafumi Kubota, Naiara Garcia-Losarcos, Hans Luders
doi : 10.1002/epd2.20002
To describe blinking as the only manifestation of seizures from isolated focal and generalized cortical spikes and investigate the relationship between blinks and epileptic discharges.
Eslicarbazepine acetate for the treatment of status epilepticus
Yaroslav Winter, Katharina Sandner, Thomas Vieth, Sergiu Groppa
doi : 10.1002/epd2.20004
Due to the high mortality of patients with refractory status epilepticus (SE), new antiseizure medications (ASMs) are needed to improve long-term outcomes. In this study, we evaluated the efficacy and safety of eslicarbazepine acetate (ESL), a new sodium channel blocker, based on the data from a large epilepsy register.
The value of serum albumin concentration in predicting functional outcome of status epilepticus: An observational study
Qiao Liao, Si-Zhuo Li, Qian-Qian Zeng, Jin-Xia Zhou, Kun Huang, Fang-Fang Bi
doi : 10.1002/epd2.20001
Status epilepticus (SE) is a common neurological emergency with unsatisfying prognoses, and accurate prediction of functional outcome is beneficial in clinical decision-making. The relationship between serum albumin concentration and outcome of SE patients has yet to be unveiled.
WISC-IV intellectual profiles in Italian children with self-limited epilepsy with centrotemporal spikes
Martina Paola Zanaboni, Ludovica Pasca, Stefania Maria Bova, Matteo Alessio Chiappedi, Melissa Filippini, Lucio Giordano, Serena Grumi, Serena Micheletti, Francesca F. Operto, Dario Pruna, Francesca Ragona, Federico Raviglione, Martina Totaro, Costanza Varesio, Aglaia Vignoli, Valentina De Giorgis, The EpilEpsyIt study group
doi : 10.1002/epd2.20003
This study aimed to describe the intellectual profile based on the Wechsler Intelligence Scale for Children 4th edition (WISC-IV) in children with self-limited epilepsy with centrotemporal spikes (SeLECTS), with an attempt to define possible predictive epilepsy-related variables of cognitive performance.
Analysis of spatio-temporal propagation of occipito-frontal spikes in childhood epilepsies by 3D sequential voltage mapping and dipole localization
Neetha Balaram, James Jose, Abdul V. Gafoor, Smita Balachandran, Joe James, Aparna Ramachandran, Shivakumar H Ramesh, Anjana Prabhakaran
doi : 10.1002/epd2.20009
We sought to study the spatio-temporal propagation of occipito-frontal spikes in childhood epilepsies by voltage mapping and dipole localization and identify types of occipito-frontal spikes based on onset, propagation, and stability of their dipoles.
Photosensitive occipital lobe epilepsy: Delineation of an under-recognized reflex epilepsy syndrome according to the new ILAE criteria and long-term follow-up
Tuba CerrahoÄŸlu Åžirin, Tülay Yılmaz, AyÅŸe Deniz Elmalı, Nerses Bebek, Veysi Demirbilek, Betül Baykan
doi : 10.1002/epd2.20011
Photosensitive occipital lobe epilepsy (POLE) should be suspected in patients with occipital lobe seizures triggered by photic stimuli, who have normal motor-mental development and brain imaging. We aimed to examine the clinical, electrophysiological, and prognostic features of POLE, which is a rare and under-investigated syndrome.
Depression and anxiety in caregivers of patients with functional seizures
Konstantinos Tsamakis, Diane L. Teagarden, Hannah K. Villarreal, Latasha Evans, Matthew L. Morton, Nicholas J. Janocko, Olivia Groover, Kelsey C. Hewitt, Michele E. Price, David W. Loring, Daniel L. Drane, Ioannis Karakis
doi : 10.1002/epd2.20014
Contrary to patients, the psychological impact of functional seizures to caregivers has not been adequately investigated. This study aimed to evaluate the rates and determinants of depression and anxiety in caregivers of patients with functional seizures.
Epilepsy and cerebral developmental venous anomalies (DVAs): A systematic review
Tahir El Meskine, Jimmy Li, Julia Reise, Dènahin Hinnoutondji Toffa
doi : 10.1002/epd2.20020
Cerebral developmental venous anomalies (DVAs) are frequent and rarely symptomatic. When symptomatic, DVAs may present with seizures; however, little is known about the characteristics of DVA-related epilepsy. In this systematic review, we aim to describe the clinical and paraclinical features of patients with DVA-related epilepsy.
What are the predominant predictors of seizure relapse following discontinuation of anti-seizure medication in epileptic children?
Seda Kanmaz, Dilara Ece Toprak, Cemile Busra Olculu, Ipek Dokurel, Erdem Simsek, Hepsen Mine Serin, Sanem Yılmaz, Gul Aktan, Sarenur Gokben, Hasan Tekgul
doi : 10.1002/epd2.20019
The aim of the study was to identify the predominant predictors of seizure relapse following discontinuation of ASM in epileptic children.
Serum neurofilament light chain in patients with epilepsy and cognitive impairment
Masamichi Ueda, Masashi Suzuki, Mai Hatanaka, Tomohiko Nakamura, Masaaki Hirayama, Masahisa Katsuno
doi : 10.1002/epd2.20024
The neurofilament light chain (NfL) is receiving increased attention as a biomarker of neurological diseases, as NfL concentration elevated in the blood and cerebrospinal fluid after neuronal damage. However, few studies have addressed NfL in epilepsy. We aimed to investigate the alteration of serum NfL in adult patients with epilepsy, and the association between this biomarker and cognitive impairment.
Seizure control during spontaneous battery failure with responsive neurostimulation
Ryan Ward, Alexandra C. Vallera, Irfan Ali, Cemal Karakas, Zulfi Haneef
doi : 10.1002/epd2.20022
We examined seizure control during spontaneous responsive neurostimulation (RNS) battery failure to investigate the persistent benefits of RNS in the absence of neurostimulation. We hypothesized that the loss of direct RNS does not immediately result in seizure worsening.
Factors associated with preoperative and early and late postoperative seizures in patients with supratentorial meningiomas
Ivan Bogdanovic, Aleksandar Ristic, Rosanda Ilic, Vladimir Bascarevic, Zoran Bukumiric, Aleksandar Miljkovic, Filip Milisavljevic, Aleksandar Stepanovic, Igor Lazic, Danica Grujicic
doi : 10.1002/epd2.20021
Risk factors for epilepsy in meningioma patients are not yet clearly defined, however, seizure freedom is a significant factor for quality of life after surgery.
Outcomes following a multi-disciplinary pediatric-to-adult transition and transfer clinic at a level four epilepsy center
Selina S. Vickery, Sarita Maturu, Nabil Khandker, Mariah Eisner, Jaime-Dawn E. Twanow
doi : 10.1002/epd2.20027
Transition and transfer from the pediatric to adult care model is crucial to the continued long-term health and well-being of patients impacted by life-long diseases. This project explores the impact of a novel epilepsy transition collaboration between Nationwide Children's Hospital (NCH) and Ohio State University (OSU) Wexner Medical Center.
Treatment of seizures by bloodletting: A call for raised awareness of unfamiliar customs followed by forcibly displaced individuals worldwide
Itay Tokatly Latzer, Raviv Markovitz, Moran Hausman-Kedem, Shimrit Uliel-Sibony
doi : 10.1002/epd2.20006
Visual-sensitive epilepsy in GLUT-1 deficiency syndrome: Expanding the phenotype
Alfiya Fazal, Manna Jose, Pavan Kumar Rudrabhatla, Soumya V. Chandrasekharan, Soumya Sundaram, Ashalatha Radhakrishnan, Moinak Banerjee, Ramshekhar N. Menon
doi : 10.1002/epd2.20008
Gelastic seizures and “smiling spasms�: A peculiar ictal pattern
Tommaso Lo Barco, Laura Corona, Roberta Solazzi, Elena Fiorini, Giulia Galati, Alberto Cossu, Jacopo Proietti, Stefano Francione, Bernardo Dalla Bernardina, Francesca Darra, Gaetano Cantalupo
doi : 10.1002/epd2.20012
Focal cortical dysplasia IIb: Near-continuous rhythmic fast spike burst pattern on intracranial EEG with atypical electroclinical-clinical semiology
Irfan S. Sheikh, Fabio A. Nascimento, Amrit Misra, Melanie Lang-Orsini, Andrew J. Cole, R. Mark Richardson, Sydney S. Cash
doi : 10.1002/epd2.20018
The foramen ovale correlate of 14 and 6/second positive bursts
ThaÃÂs de Maria Frota Vasconcelos, Ricardo Lutzky Saute, Guilherme Podolsky-Gondim, Veriano Alexandre, Marina Teixeira Ramalho Pereira Dalio, Frederico Nakane Nakano, Tonicarlo Rodrigues Velasco, João Pereira Leite, Americo Ceiki Sakamoto
doi : 10.1002/epd2.20016
Comment on: “The ventral precuneal-posterior cingulate region as a site of epileptogenicity�
Taryn Ariadna Castro Cuesta, Igor Lima Maldonado
doi : 10.1002/epd2.20007
Response to “Comment on: The ventral precuneal-posterior cingulate region as a site of epileptogenicity�
Lee Elisevich, Kost Elisevich
doi : 10.1002/epd2.20056
Focal cortical dysplasias: New advances for curing epilepsy
George Tamula, Roohi Katyal, Sándor Beniczky, Fábio A. Nascimento
doi : 10.1002/epd2.20013
