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JAMA Ophthalmology—The Year in Review, 2022
Neil M. Bressler, MD1,2
doi : 10.1001/jamaophthalmol.2023.0587
May 2023, Vol 141, No. 5, Pages 420-500
Pulsed Oral Azithromycin vs 6-Week Oral Doxycycline for Moderate to Severe Meibomian Gland Dysfunction
Phit Upaphong, MD1; Chulaluck Tangmonkongvoragul, MD1; Phichayut Phinyo, MD, PhD2,3,4
Epidemiologic Pattern and Injury Mechanism of Intimate Partner Violence–Related Ocular Trauma in the US
Maya Alik, BHSc1; Mishaal Malik, BS2; Reza Ashrafi, HSD3; Albert Y. Wu, MD, PhD4
doi : 10.1001/jamaophthalmol.2023.0578
Importance Intimate partner violence (IPV) is an important cause of death and disability worldwide. The literature estimates that 45% of IPV injuries involve the eyes. Many medical fields have increased IPV-related research; however, ophthalmology IPV research remains rare.
Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data
Ian Dorney, BS1; Jacqueline Shaia, MS2; David C. Kaelber, MD, PhD, MPH3,4; Katherine E. Talcott, MD2; Rishi P. Singh, MD2
doi : 10.1001/jamaophthalmol.2023.0610
Importance New-onset retinal vascular occlusion (RVO) occurring acutely after messenger RNA (mRNA) COVID-19 vaccination has been described in recent literature. Because RVO can cause vision loss or blindness, an epidemiologic investigation evaluating this potential association is of great importance to public health.
Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration
Joel T. Rämö, MD, PhD1,2,3,4; Erik Abner, PhD5; Elon H. C. van Dijk, MD, PhD6; Xin Wang, MD3; Joost Brinks, MD5; Tiit Nikopensius, PhD6; Margit Nõukas, MSc6,7; Heidi Marjonen, PhD8; Kaisa Silander, PhD8; Sakari Jukarainen, MD, PhD1; Tuomo Kiiskinen, MD1; Seung Hoan Choi, PhD3,9; Risto Kajanne, PhD1; Juha Mehtonen, MSc1; Priit Palta, PhD1,5; Steven A. Lubitz, MD, PhD3,10; Kai Kaarniranta, MD, PhD11; Lucia Sobrin, MD, MPH12; Mitja Kurki, PhD1,13,14; Suzanne Yzer, MD, PhD15,16; Patrick T. Ellinor, MD, PhD3,10; Tõnu Esko, PhD5,7; Mark J. Daly, PhD1,17,18; Anneke I. den Hollander, PhD15,19; Aarno Palotie, MD, PhD1,14,18,20,21; Joni A. Turunen, MD, PhD22,23; Camiel J. F. Boon, MD, PhD, FEBO6,24; Elizabeth J. Rossin, MD, PhD12,25; for the FinnGen Study; for the Estonian Biobank Research Team
doi : 10.1001/jamaophthalmol.2023.0706
Importance Central serous chorioretinopathy (CSC) is a serous maculopathy of unknown etiology. Two of 3 previously reported CSC genetic risk loci are also associated with AMD. Improved understanding of CSC genetics may broaden our understanding of this genetic overlap and unveil mechanisms in both diseases.
Efficacy and Safety of a Water-Free Topical Cyclosporine, 0.1%, Solution for the Treatment of Moderate to Severe Dry Eye Disease
Esen K. Akpek, MD1; David L. Wirta, MD2; Johnathon E. Downing, MD3; Joseph Tauber, MD4; John D. Sheppard, MD5; Joseph B. Ciolino, MD6; Alice S. Meides, PhD7; Sonja Krösser, PhD7
doi : 10.1001/jamaophthalmol.2023.0709
Importance Dry eye disease (DED) is a common public health problem with significant impact on vision-related quality of life and well-being of patients. Medications with rapid onset of action and a good tolerability profile remain an unmet need.
Association Between Social Determinants of Health and Examination-Based Vision Loss vs Self-reported Vision Measures
Katelin M Alfaro Hudak, PhD, MID1; John S. Wittenborn, BS1; Phoebe A. Lamuda, SM1; Elizabeth A. Lundeen, PhD, MPH2; Jinan Saaddine, MD, MPH2; David B. Rein, PhD, MPA1
doi : 10.1001/jamaophthalmol.2023.0723
Importance Recent evidence suggests that social determinants of health (SDOH) affect vision loss, but it is unclear whether estimated associations differ between clinically evaluated and self-reported vision loss.
Epidemiology of Retinopathy of Prematurity in the US From 2003 to 2019
Anshul Bhatnagar, BA1; Henry C. Skrehot, BA1; Amit Bhatt, MD2; Honey Herce, MD2; Christina Y. Weng, MD, MBA3
doi : 10.1001/jamaophthalmol.2023.0809
Importance Retinopathy of prematurity (ROP) is a potentially blinding retinal disease with poorly defined epidemiology. Understanding of which infants are most at risk for developing ROP may foster targeted detection and prevention efforts.
Association of Gaps in Health Insurance Coverage With Unmet Needs for Vision Care Among Adults in Ohio
Mufida Muhammad, BS1; Johnny Vang, MS1; Dmitry Tumin, PhD2,3
doi : 10.1001/jamaophthalmol.2023.0847
Importance Access to vision care is vital to diagnose and treat vision impairment and diseases. Previous studies found that currently uninsured adults have limited access to vision care. It is unclear whether a recent history (past 12 months) of gaps in insurance coverage likewise adversely affects access to vision care.
Evaluating the Evidence for Treatment of Meibomian Gland Dysfunction With Oral Antibiotics
B. Michele Melia, ScM1
Intimate Partner Violence and the Role of Ophthalmology
Annette K. Hoskin, MBA, PhD1,2; Stephanie L. Watson, PhD1
No Red Flags for Risk of Retinal Vascular Occlusion After mRNA COVID-19 Vaccination
Lee M. Jampol, MD1; Maureen G. Maguire, PhD2,3
What Can We Learn From the Surprising Insight Into the Genetic Background of Age-Related Macular Degeneration and Central Serous Chorioretinopathy?
Samer Khateb, MD, PhD1; Itay Chowers, MD1; Michelle Grunin, PhD2,3
Comparison of Water-Free Commercially Available Cyclosporine Ophthalmic Preparations—Different, but the Same
Andrea Naranjo Lozano, MD1; Alice Shen, MD1; Jennifer Rose-Nussbaumer, MD1
A Vision for Addressing Social Needs and Social Determinants of Health
Alex R. Kemper, MD, MPH, MS1,2; Kelly J. Kelleher, MD, MPH2; Laura J. Chavez, PhD, MPH2
Nationwide Increase in the Incidence of Retinopathy of Prematurity in the US—A Growing Problem?
Gui-shuang Ying, PhD1; Graham E. Quinn, MD, MSCE1,2
Unmet Needs in Vision Care Among Vulnerable Patients
Ivan A. Copado, BA1,2; Sally L. Baxter, MD, MSc1,2
Potential Rare Danger of Presumably Benign Artificial Tears
Christina R. Prescott, MD, PhD1; Kathryn A. Colby, MD, PhD1
Blurred Vision After a Kidney Transplant
Prashant D. Tailor, MD1; Wendy M. Smith, MD1; Lauren A. Dalvin, MD1
Multidrug-Resistant Pseudomonas aeruginosa Keratitis Associated With Artificial Tear Use
Marissa K. Shoji, MD1; Naomi E. Gutkind, MD1; Benjamin I. Meyer, MD1; Ramsey Yusuf, MD1; Jesse D. Sengillo, MD1; Guillermo Amescua, MD1; Darlene Miller, DHSc1
Pseudomonas aeruginosa Corneal Ulcer Associated With Artificial Tears Eye Drops
Morgan K. Morelli, MD1; Amy Kloosterboer, MD2; Ahmed F. Omar, MD2,3
Subretinal Deposits Associated With Type 1 Cryoglobulinemia
Huan Chen, MD1,2; Yang Zhang, MD1,2; Rongping Dai, MD1,2
Intravitreal Glioma in a Boy Aged 7 Years
Alexandre Dentel, MD1; Dominique Bremond-Gignac, MD, PhD1,2; Matthieu P. Robert, MD, PhD1,2
Subconjunctival Thelazia in a Chinese Woman Aged 49 Years
Luyao Tong, MD1,2; Zongduan Zhang, MD1
Double Optic Disc Pit With Retinal Pigmentation in a Woman With High Myopia
Zhiyan Xu, MD1,2; Zhikun Yang, MD1,2
