Evan Wood, MD, PhD1; Eri D. Solomon2; Scott E. Hadland, MD, MPH, MS3,4
doi : 10.1001/jamainternmed.2023.0116
May 2023, Vol 183, No. 5, Pages 400-500
Amy N. Duckro, DO, MPH1; John F. Steiner, MD, MPH2
Juan Sanchis, PhD1; Héctor Bueno, PhD2; Gema Miñana, PhD1; Carme Guerrero, MD3; David MartÃ, MD4; Manuel MartÃnez-Sellés, PhD5; Laura DomÃnguez-Pérez, MD2; Pablo DÃez-Villanueva, MD6; Jose A. Barrabés, PhD7; Francisco MarÃn, PhD8; Adolfo Villa, MD9; Marcelo SanmartÃn, MD10; Cinta Llibre, MD11; Alessandro SionÃs, PhD12; Antoni Carol, MD13; Sergio GarcÃa-Blas, PhD1; Elena Calvo, MD3; MarÃa José Morales Gallardo, MD4; Jaime ElÃzaga, PhD5; Iván Gómez-Blázquez, MD2; Fernando Alfonso, PhD6; Bruno GarcÃa del Blanco, MD7; Julio Núñez, PhD1; Francesc Formiga, PhD3; Albert Ariza-Solé, PhD3
doi : 10.1001/jamainternmed.2023.0047
Importance To our knowledge, no randomized clinical trial has compared the invasive and conservative strategies in frail, older patients with non–ST-segment elevation acute myocardial infarction (NSTEMI).
Shreya P. Trivedi, MD1,2; Sara Corderman, MD3; Elyse Berlinberg, BS4; Antoinette Schoenthaler, EdD5; Leora I. Horwitz, MD, MHS6
doi : 10.1001/jamainternmed.2023.0070
Importance Patient education at time of hospital discharge is critical for smooth transitions of care; however, empirical data regarding discharge communication are limited.
Audrey H. Calderwood, MD, MS1,2; Tor D. Tosteson, ScD2,3,4; Qianfei Wang, MS2; Tracy Onega, PhD, MPAS5; Louise C. Walter, MD6,7
doi : 10.1001/jamainternmed.2023.0078
Importance Surveillance after prior colon polyps is the most frequent indication for colonoscopy in older adults. However, to our knowledge, the current use of surveillance colonoscopy, clinical outcomes, and follow-up recommendations in association with life expectancy, factoring in both age and comorbidities, have not been studied.
Titas Banerjee, MD1; Myung Sun Kim, MD1; Alyson Haslam, PhD2; Vinay Prasad, MD2
doi : 10.1001/jamainternmed.2023.0190
Importance Idelalisib is a first-in-class phosphatidylinositol 3-kinase inhibitor that received US Food and Drug Administration accelerated approval in July 2014 as a single-agent treatment for relapsed follicular lymphoma (FL) and small lymphocytic lymphoma (SLL). Serious adverse effects were reported in 2016 leading to termination of postmarketing registry trials. However, idelalisib remained on the market until 2022 when Gilead voluntarily withdrew the drug for the accelerated approval indication.
Zachary J. Kunicki, PhD, MS, MPH1; Long H. Ngo, PhD2; Edward R. Marcantonio, MD, SM3; Douglas Tommet, MS1; Yi Feng, MA4; Tamara G. Fong, MD, PhD5; Eva M. Schmitt, PhD6; Thomas G. Travison, PhD3; Richard N. Jones, ScD1; Sharon K. Inouye, MD, MPH3
doi : 10.1001/jamainternmed.2023.0144
Importance The study results suggest that delirium is the most common postoperative complication in older adults and is associated with poor outcomes, including long-term cognitive decline and incident dementia.
Nicholas A. Bosch, MD, MSc1; Bijan Teja, MD2,3; Anica C. Law, MD, MS1; Brandon Pang, MD1; S. Reza Jafarzadeh, DVM, MPVM, PhD4; Allan J. Walkey, MD, MSc1
doi : 10.1001/jamainternmed.2023.0258
Importance Patients with septic shock may benefit from the initiation of corticosteroids. However, the comparative effectiveness of the 2 most studied corticosteroid regimens (hydrocortisone with fludrocortisone vs hydrocortisone alone) is unclear.
Susan P. Y. Wong, MD, MS1; David K. Prince, PhD1; Manjula Kurella Tamura, MD, MPH2; Yoshio N. Hall, MD, MS1; Catherine R. Butler, MD, MA1; Ruth A. Engelberg, PhD1; Elizabeth K. Vig, MD, MPH1; J. Randall Curtis, MD, MPH2,3; Ann M. O’Hare, MD, MA1
doi : 10.1001/jamainternmed.2023.0265
Importance Patients receiving maintenance dialysis experience intensive patterns of end-of-life care that might not be consistent with their values.
Weiwei Beckerleg, MD, MPH1,2; Daniel Kobewka, MD, MSc1,3,4; Duminda N. Wijeysundera, MD, PhD5,6,7; Manish M. Sood, MD, MSc2,3,4,8; Daniel I. McIsaac, MD, MPH2,3,4,9
doi : 10.1001/jamainternmed.2023.0325
Importance It is uncertain whether preoperative medical consultation reduces adverse postoperative clinical outcomes.
Rita F. Redberg, MD, MSc1,2
Andrew J. Foy, MD1; David L. Brown, MD2
Charlie M. Wray, DO, MS1,2; Christine D. Jones, MD, MS3,4
Michael A. Matthay, MD1; Issa J. Dahabreh, MD, ScD2; B. Taylor Thompson, MD3
Mutya Mithi Del Rosario, MD1,2; Rita F. Redberg, MD, MSc3,4; Deborah Grady, MD, MPH3,5
Kirsten A. Dickins, PhD, AM, APRN, FNP-C1,2,3; Danielle R. Fine, MD, MSc3,4; Logan D. Adams, MD4; Nora K. Horick, MS5; Elizabeth Lewis, MBA6,7; Sara E. Looby, PhD, APN-BC2,3,8; Travis P. Baggett, MD, MPH3,4,6
Nishant Uppal, MD, MBA1,2; Timothy S. Anderson, MD, MAS2,3,4
Kelly M. Potter, PhD, RN, CNE1; Valerie Danesh, PhD, RN2; Brad W. Butcher, MD3; Tammy L. Eaton, PhD, MSc, RN, FNP-BC4; Anthony D. McDonald, PhD5; Timothy D. Girard, MD, MSCI1
Laszlo Littmann, MD, PhD1
Anping Cai, MD1; Zhiming Chen, MD2; Fengguang Kang, MD3
Xingli Xin, MD1; Xuanxuan Li, MD2; Qingjie Xin, MD3
Ziming Zhuang, MD1; Yangyi Lin, MD2
Grace Y. Zhang, MD1,2; Michael A. Incze, MD, MSEd3,4
Robert A. Lowe, MD, MPH1
Adam A. Dalia, MD, MBA1; Timothy Houle, PhD1; Jeanine Wiener-Kronish, MD1
Achia Nemet, MD1; Raimo Tuuminen, MD, PhD2,3
Dhivya Perumal, MD1; Sei J. Lee, MD, MAS2,3; Catherine L. Chen, MD, MPH1,4
Sanne S. Mooldijk, BSc1; Silvan Licher, MD, PhD1; Frank J. Wolters, MD, PhD1
William James Deardorff, MD1,2; Alexander K. Smith, MD, MS, MPH1,2; Sei J. Lee, MD, MAS1,2
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