JAMA Internal Medicine




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Universal Precautions for People at Risk of Opioid Overdose in North America

Evan Wood, MD, PhD1; Eri D. Solomon2; Scott E. Hadland, MD, MPH, MS3,4

doi : 10.1001/jamainternmed.2023.0116

May 2023, Vol 183, No. 5, Pages 400-500

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Evaluating the Role of System-Generated Communications in Health Care Organizations

Amy N. Duckro, DO, MPH1; John F. Steiner, MD, MPH2

doi : 10.1001/jamainternmed.2023.0273

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Effect of Routine Invasive vs Conservative Strategy in Older Adults With Frailty and Non–ST-Segment Elevation Acute Myocardial Infarction

Juan Sanchis, PhD1; Héctor Bueno, PhD2; Gema Miñana, PhD1; Carme Guerrero, MD3; David Martí, MD4; Manuel Martínez-Sellés, PhD5; Laura Domínguez-Pérez, MD2; Pablo Díez-Villanueva, MD6; Jose A. Barrabés, PhD7; Francisco Marín, PhD8; Adolfo Villa, MD9; Marcelo Sanmartín, MD10; Cinta Llibre, MD11; Alessandro Sionís, PhD12; Antoni Carol, MD13; Sergio García-Blas, PhD1; Elena Calvo, MD3; María José Morales Gallardo, MD4; Jaime Elízaga, PhD5; Iván Gómez-Blázquez, MD2; Fernando Alfonso, PhD6; Bruno García del Blanco, MD7; Julio Núñez, PhD1; Francesc Formiga, PhD3; Albert Ariza-Solé, PhD3

doi : 10.1001/jamainternmed.2023.0047

Importance  To our knowledge, no randomized clinical trial has compared the invasive and conservative strategies in frail, older patients with non–ST-segment elevation acute myocardial infarction (NSTEMI).

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Assessment of Patient Education Delivered at Time of Hospital Discharge

Shreya P. Trivedi, MD1,2; Sara Corderman, MD3; Elyse Berlinberg, BS4; Antoinette Schoenthaler, EdD5; Leora I. Horwitz, MD, MHS6

doi : 10.1001/jamainternmed.2023.0070

Importance  Patient education at time of hospital discharge is critical for smooth transitions of care; however, empirical data regarding discharge communication are limited.

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Association of Life Expectancy With Surveillance Colonoscopy Findings and Follow-up Recommendations in Older Adults

Audrey H. Calderwood, MD, MS1,2; Tor D. Tosteson, ScD2,3,4; Qianfei Wang, MS2; Tracy Onega, PhD, MPAS5; Louise C. Walter, MD6,7

doi : 10.1001/jamainternmed.2023.0078

Importance  Surveillance after prior colon polyps is the most frequent indication for colonoscopy in older adults. However, to our knowledge, the current use of surveillance colonoscopy, clinical outcomes, and follow-up recommendations in association with life expectancy, factoring in both age and comorbidities, have not been studied.

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Clinical Trials Portfolio and Regulatory History of Idelalisib in Indolent Non-Hodgkin Lymphoma

Titas Banerjee, MD1; Myung Sun Kim, MD1; Alyson Haslam, PhD2; Vinay Prasad, MD2

doi : 10.1001/jamainternmed.2023.0190

Importance  Idelalisib is a first-in-class phosphatidylinositol 3-kinase inhibitor that received US Food and Drug Administration accelerated approval in July 2014 as a single-agent treatment for relapsed follicular lymphoma (FL) and small lymphocytic lymphoma (SLL). Serious adverse effects were reported in 2016 leading to termination of postmarketing registry trials. However, idelalisib remained on the market until 2022 when Gilead voluntarily withdrew the drug for the accelerated approval indication.

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Six-Year Cognitive Trajectory in Older Adults Following Major Surgery and Delirium

Zachary J. Kunicki, PhD, MS, MPH1; Long H. Ngo, PhD2; Edward R. Marcantonio, MD, SM3; Douglas Tommet, MS1; Yi Feng, MA4; Tamara G. Fong, MD, PhD5; Eva M. Schmitt, PhD6; Thomas G. Travison, PhD3; Richard N. Jones, ScD1; Sharon K. Inouye, MD, MPH3

doi : 10.1001/jamainternmed.2023.0144

Importance  The study results suggest that delirium is the most common postoperative complication in older adults and is associated with poor outcomes, including long-term cognitive decline and incident dementia.

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Comparative Effectiveness of Fludrocortisone and Hydrocortisone vs Hydrocortisone Alone Among Patients With Septic Shock

Nicholas A. Bosch, MD, MSc1; Bijan Teja, MD2,3; Anica C. Law, MD, MS1; Brandon Pang, MD1; S. Reza Jafarzadeh, DVM, MPVM, PhD4; Allan J. Walkey, MD, MSc1

doi : 10.1001/jamainternmed.2023.0258

Importance  Patients with septic shock may benefit from the initiation of corticosteroids. However, the comparative effectiveness of the 2 most studied corticosteroid regimens (hydrocortisone with fludrocortisone vs hydrocortisone alone) is unclear.

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Value Placed on Comfort vs Life Prolongation Among Patients Treated With Maintenance Dialysis

Susan P. Y. Wong, MD, MS1; David K. Prince, PhD1; Manjula Kurella Tamura, MD, MPH2; Yoshio N. Hall, MD, MS1; Catherine R. Butler, MD, MA1; Ruth A. Engelberg, PhD1; Elizabeth K. Vig, MD, MPH1; J. Randall Curtis, MD, MPH2,3; Ann M. O’Hare, MD, MA1

doi : 10.1001/jamainternmed.2023.0265

Importance  Patients receiving maintenance dialysis experience intensive patterns of end-of-life care that might not be consistent with their values.

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Association of Preoperative Medical Consultation With Reduction in Adverse Postoperative Outcomes and Use of Processes of Care Among Residents of Ontario, Canada

Weiwei Beckerleg, MD, MPH1,2; Daniel Kobewka, MD, MSc1,3,4; Duminda N. Wijeysundera, MD, PhD5,6,7; Manish M. Sood, MD, MSc2,3,4,8; Daniel I. McIsaac, MD, MPH2,3,4,9

doi : 10.1001/jamainternmed.2023.0325

Importance  It is uncertain whether preoperative medical consultation reduces adverse postoperative clinical outcomes.

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JAMA Internal Medicine—The Year in Review, 2022

Rita F. Redberg, MD, MSc1,2

doi : 10.1001/jamainternmed.2022.6198

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Importance of Designing Trials for Older Adults With Complex Medical Conditions

Andrew J. Foy, MD1; David L. Brown, MD2

doi : 10.1001/jamainternmed.2023.0046

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Bridging the Know-Do Gap in Hospital Care Transitions

Charlie M. Wray, DO, MS1,2; Christine D. Jones, MD, MS3,4

doi : 10.1001/jamainternmed.2023.0069

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Should We Add Fludrocortisone to Hydrocortisone for Treatment of Septic Shock?

Michael A. Matthay, MD1; Issa J. Dahabreh, MD, ScD2; B. Taylor Thompson, MD3

doi : 10.1001/jamainternmed.2023.0257

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Preoperative Medical Consultation—Time to Reevaluate a Questionable Process

Mutya Mithi Del Rosario, MD1,2; Rita F. Redberg, MD, MSc3,4; Deborah Grady, MD, MPH3,5

doi : 10.1001/jamainternmed.2023.0331

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Mortality Trends Among Adults Experiencing Homelessness in Boston, Massachusetts From 2003 to 2018

Kirsten A. Dickins, PhD, AM, APRN, FNP-C1,2,3; Danielle R. Fine, MD, MSc3,4; Logan D. Adams, MD4; Nora K. Horick, MS5; Elizabeth Lewis, MBA6,7; Sara E. Looby, PhD, APN-BC2,3,8; Travis P. Baggett, MD, MPH3,4,6

doi : 10.1001/jamainternmed.2022.7011

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Association Between Pharmaceutical Industry Marketing Payments to Physicians and Intra-articular Hyaluronic Acid Administration to Medicare Beneficiaries

Nishant Uppal, MD, MBA1,2; Timothy S. Anderson, MD, MAS2,3,4

doi : 10.1001/jamainternmed.2022.7018

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Return to Driving After Critical Illness

Kelly M. Potter, PhD, RN, CNE1; Valerie Danesh, PhD, RN2; Brad W. Butcher, MD3; Tammy L. Eaton, PhD, MSc, RN, FNP-BC4; Anthony D. McDonald, PhD5; Timothy D. Girard, MD, MSCI1

doi : 10.1001/jamainternmed.2022.7096

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Computer-Estimated Heart Rate vs True Heart Rate—Be Aware of the Software

Laszlo Littmann, MD, PhD1

doi : 10.1001/jamainternmed.2022.6613

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Giant T-wave Inversion in an Older Patient With Sudden Loss of Consciousness

Anping Cai, MD1; Zhiming Chen, MD2; Fengguang Kang, MD3

doi : 10.1001/jamainternmed.2022.6618

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Incorrect ECG Diagnoses?—Follow the Leads

Xingli Xin, MD1; Xuanxuan Li, MD2; Qingjie Xin, MD3

doi : 10.1001/jamainternmed.2022.6944

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Brugada Pattern, Tall Peaked T Waves, Absence of P Waves, and Broad QRS Complexes

Ziming Zhuang, MD1; Yangyi Lin, MD2

doi : 10.1001/jamainternmed.2022.7027

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What Should I Know About Stopping Routine Cancer Screening?

Grace Y. Zhang, MD1,2; Michael A. Incze, MD, MSEd3,4

doi : 10.1001/jamainternmed.2023.0088

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Recall of Philips Respironics Ventilators and CPAP Machines—Breakdowns in Medical Device Surveillance

Robert A. Lowe, MD, MPH1

doi : 10.1001/jamainternmed.2023.0066

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Perioperative Risk Assessment and Avoiding Overuse of Anesthesia Care for Routine Cataract Surgery

Adam A. Dalia, MD, MBA1; Timothy Houle, PhD1; Jeanine Wiener-Kronish, MD1

doi : 10.1001/jamainternmed.2023.0167

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Perioperative Risk Assessment and Avoiding Overuse of Anesthesia Care for Routine Cataract Surgery

Achia Nemet, MD1; Raimo Tuuminen, MD, PhD2,3

doi : 10.1001/jamainternmed.2023.0170

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Perioperative Risk Assessment and Avoiding Overuse of Anesthesia Care for Routine Cataract Surgery—Reply

Dhivya Perumal, MD1; Sei J. Lee, MD, MAS2,3; Catherine L. Chen, MD, MPH1,4

doi : 10.1001/jamainternmed.2023.0176

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Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia

Sanne S. Mooldijk, BSc1; Silvan Licher, MD, PhD1; Frank J. Wolters, MD, PhD1

doi : 10.1001/jamainternmed.2023.0173

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Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia—Reply

William James Deardorff, MD1,2; Alexander K. Smith, MD, MS, MPH1,2; Sei J. Lee, MD, MAS1,2

doi : 10.1001/jamainternmed.2023.0179

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JAMA Internal Medicine Peer Reviewers in 2022

doi : 10.1001/jamainternmed.2023.0182

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