One-year access to more than 500 world journals available in the system
-
http://medilib.ir
- Duration of Time : 365 Day
Price : 300$- Special Price : 100$
Sperm sharing: as problematic as oocyte sharing?
Guido Pennings
doi : 10.1093/humrep/deac087
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1101–1105
Sperm sharing has recently been introduced in a number of clinics in the UK. In all gamete sharing schemes, two goals can be distinguished: increasing the donor pool and enabling less affluent patients to access IVF treatment.
Sperm selection with hyaluronic acid improved live birth outcomes among older couples and was connected to sperm DNA quality, potentially affecting all treatment outcomes
Robert West, Arri Coomarasamy, Lorraine Frew, Rachel Hutton, Jackson Kirkman-Brown, Martin Lawlor, Sheena Lewis, Riitta Partanen, Alex Payne-Dwyer, Claudia Román-Montañana, Forough Torabi, Sofia Tsagdi, David Miller
doi : 10.1093/humrep/deac058
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1106–1125
Recent randomized controlled trials (RCTs) investigating the efficacy of HA-based sperm selection prior to ICSI, including HABSelect, have consistently reported reductions in the numbers of miscarriages among couples randomized to the intervention, suggesting a pathological sperm-mediated factor mitigated by prior HA-binding/selection. The mechanism of that protection is unknown.
SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during the pandemic
Neerujah Balachandren, Melanie C Davies, Jennifer A Hall, Judith M Stephenson, Anna L David, Geraldine Barrett, Helen C O’Neill, George B Ploubidis, Ephia Yasmin, Dimitrios Mavrelos
doi : 10.1093/humrep/deac062
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1126–1133
Viral infections during pregnancy have a broad spectrum of placental and neonatal pathology. Data on the effects of the SARS-CoV-2 infection in pregnancy are still emerging.
How slow is too slow? A comprehensive portrait of Day 7 blastocysts and their clinical value standardized through artificial intelligence
Danilo Cimadomo, Daria Soscia, Valentina Casciani, Federica Innocenti, Samuele Trio, Viviana Chiappetta, Laura Albricci, Roberta Maggiulli, Itay Erlich, Assaf Ben-Meir, Iris Har-Vardi, Alberto Vaiarelli, Filippo Maria Ubaldi, Laura Rienzi
doi : 10.1093/humrep/deac080
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1134–1147
Many studies showed that Day 7 blastocysts are clinically valuable, although less euploid and less competent than faster-growing embryos. Nevertheless, a large variability exists in: (i) the definition of ‘Day 7’; (ii) the criteria to culture embryos to Day 7; (iii) the clinical setting; (iv) the local regulation; and/or (v) the culture strategies and incubators.
The higher the score, the better the clinical outcome: retrospective evaluation of automatic embryo grading as a support tool for embryo selection in IVF laboratories
Lorena Bori, Fernando Meseguer, M Angeles Valera, Arancha Galan, Jose Remohi, Marcos Meseguer
doi : 10.1093/humrep/deac066
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1148–1160
Is the automatic embryo grading function of specific time-lapse systems clinically useful as a decision support tool for IVF laboratories?
A randomized, controlled, first-in-patient trial of choriogonadotropin beta added to follitropin delta in women undergoing ovarian stimulation in a long GnRH agonist protocol
Manuel Fernández Sánchez, Hana Višnová, Per Larsson, Claus Yding Andersen, Marco Filicori, Christophe Blockeel, Anja Pinborg, Yacoub Khalaf, Bernadette Mannaerts, the Rainbow Study Group
doi : 10.1093/humrep/deac061
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1161–1174
CG beta is a novel recombinant hCG (rhCG) molecule expressed by a human cell line (PER.C6®) and has a different glycosylation profile compared to urinary hCG or rhCG derived from a Chinese Hamster Ovary (CHO) cell line.
Intracervical insemination versus intrauterine insemination with cryopreserved donor sperm in the natural cycle: a randomized controlled trial
P A L Kop, M van Wely, A Nap, A T Soufan, A A de Melker, B W J Mol, R E Bernardus, M De Brucker, P M W Janssens, J J P M Pieters, S Repping, F van der Veen, M H Mochtar
doi : 10.1093/humrep/deac071
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1175–1182
Both ICI and IUI in the natural cycle are performed as first-line treatments in women who are eligible for donor sperm treatment. High-quality data on the effectiveness of ICI versus IUI with cryopreserved donor sperm in the natural cycle in terms of live birth is lacking.
Dydrogesterone and 20α-dihydrodydrogesterone plasma levels on day of embryo transfer and clinical outcome in an anovulatory programmed frozen-thawed embryo transfer cycle: a prospective cohort study
Kay Neumann, Antonia Masuch, Reinhard Vonthein, Marion Depenbusch, Askan Schultze-Mosgau, Tanja K Eggersmann, Georg Griesinger
doi : 10.1093/humrep/deac045
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1183–1193
DYD is an oral, systemic alternative to vaginal progesterone for luteal phase support. The DYD and DHD level necessary to sustain implantation, when no endogenous progesterone is present, remains unknown.
IVF outcomes of embryos with abnormal PGT-A biopsy previously refused transfer: a prospective cohort study
D H Barad, D F Albertini, E Molinari, N Gleicher
doi : /10.1093/humrep/deac063
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1194–1206
: PGT-A is a widely practiced method of selecting embryos for transfer based on biopsy of a few cells. Many clinical practices refuse to transfer PGT-A abnormal embryos even when there are no other ‘normal’ embryos available.
At the crossroads of fertility and metabolism: the importance of AMPK-dependent signaling in female infertility associated with hyperandrogenism
Pascal Froment, Ingrid Plotton, Cecilia Giulivi, Stephane Fabre, Rita Khoueiry, Nizar I Mourad, Sandrine Horman, Christelle Ramé, Charlène Rouillon, Jeremy Grandhaye, Yves Bigot, Claire Chevaleyre, Remy Le Guevel, Patricia Mallegol, Ramaroson Andriantsitohaina, Fabrice Guerif, Jérôme Tamburini, Benoit Viollet, Marc Foretz, Joelle Dupont
doi : 10.1093/humrep/deac067
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1207–1228
AMPK is expressed in the ovarian follicle, and its activation by pharmacological medications, such as metformin, inhibits the production of steroids. Polycystic ovary syndrome (PCOS) is responsible for infertility in approximately 5–20% of women of childbearing age and possible treatments include reducing body weight, improving lifestyle and the administration of a combination of drugs to improve insulin resistance, such as metformin.
Taurine and its transporter TAUT positively affect male reproduction and early embryo development
Hua Wu, Xinyue Zhang, Jihong Yang, Ting Feng, Yao Chen, Ruizhi Feng, Hui Wang, Yun Qian
doi : 10.1093/humrep/deac089
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1229–1243
Taurine is one of the most abundant amino acids in the male reproductive system and it has been demonstrated that taurine can efficiently improve spermatogenic function in rat models of testicular injury. However, limited information is known about the role of taurine and its transporter TAUT in spermatogenesis and early embryo development.
Candidate genes for polycystic ovary syndrome are regulated by TGFβ in the bovine foetal ovary
Rafiatu Azumah, Menghe Liu, Katja Hummitzsch, Nicole A Bastian, Monica D Hartanti, Helen F Irving-Rodgers, Richard A Anderson, Raymond J Rodgers
doi : 10.1093/humrep/deac049
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1244–1254
The ovarian stroma arises from the mesonephros during foetal ovary development. Changes in the morphology of the ovarian stroma are cardinal features of PCOS. The ovary is more fibrous and has more tunica and cortical and subcortical stroma.
Where are we in understanding the natural history of polycystic ovary syndrome? A systematic review of longitudinal cohort studies
Sylvia Kiconco, Chau Thien Tay, Kate Louise Rassie, Ricardo Azziz, Helena J Teede, Anju E Joham
doi : 10.1093/humrep/deac077
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1255–1273
The progression of reproductive, psychological and oncological features in PCOS remains unclear, which limits prevention and early diagnosis strategies across the lifespan. Understanding the natural history of PCOS is one of the overarching priorities in PCOS research.
Transcriptomic landscape of granulosa cells and peripheral blood mononuclear cells in women with PCOS compared to young poor responders and women with normal response
Mauro Cozzolino, Sonia Herraiz, Shiny Titus, Leah Roberts, Monica Romeu, Irene Peinado, Richard T Scott, Antonio Pellicer, Emre Seli
doi : 10.1093/humrep/deac069
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1274–1286
PCOS is characterised by a higher number of follicles at all developmental stages. During controlled ovarian hyperstimulation, PCOS women develop a larger number of follicles as a result of an exacerbated response, with an increased risk of ovarian hyperstimulation syndrome.
Changes in sexual frequency among 51 150 infertile Chinese couples over the past 10 years
Yanwen Zhu, Bian Wang, Qianqian Zhu, Jing Ye, Yanping Kuang
doi : 10.1093/humrep/deac044
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1287–1296
Many researchers have explored trends in coital frequency and variables associated among healthy individuals in other nations. There have been major changes in all aspects of Chinese life and society over the past decade, including two major fertility policy adjustments. The sexual habits of infertile couples in China remain poorly understood and warrant further investigation.
Associations of sleep characteristics with outcomes of IVF/ICSI treatment: a prospective cohort study
Qing-Yun Yao, Xiao-Qiong Yuan, Chong Liu, Yao-Yao Du, Yang-Cheng Yao, Lin-Jing Wu, Hua-Hua Jiang, Tao-Ran Deng, Na Guo, Yan-Ling Deng, Qiang Zeng, Yu-Feng Li
doi : 10.1093/humrep/deac040
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1297–1310
Disturbed sleep and circadian rhythm contribute to impaired fecundity in the general population, but the effects of sleep characteristics on IVF/ICSI outcomes are largely unknown.
Association of maternal polycystic ovary syndrome and diabetes with preterm birth and offspring birth size: a population-based cohort study
Xinxia Chen, Mika Gissler, Catharina Lavebratt
doi : 10.1093/humrep/deac050
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1311–1323
PCOS is suggested to be an independent risk factor for adverse infant outcomes, and it is highly prevalent in mothers with diabetes. However, the impact of PCOS on the associations of different types of maternal diabetes with preterm birth and offspring birth sizes has not been reported.
Women with female infertility seeking medically assisted reproduction are not at increased risk of developing multiple sclerosis
T I Kopp, A Pinborg, C H Glazer, M Magyari
doi : 10.1093/humrep/deac041
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1324–1333
Women with MS have fewer children compared with women without MS. Persons with MS more often have other coexisting autoimmune disorders including hypothyroidism compared with the general population.
Whole-exome sequencing in patients with maturation arrest: a potential additional diagnostic tool for prevention of recurrent negative testicular sperm extraction outcomes
F Ghieh, A L Barbotin, N Swierkowski-Blanchard, C Leroy, J Fortemps, C Gerault, C Hue, H Mambu Mambueni, S Jaillard, M Albert, M Bailly, V Izard, D Molina-Gomes, F Marcelli, J Prasivoravong, V Serazin, M N Dieudonne, M Delcroix, H J Garchon, A Louboutin, B Mandon-Pepin, S Ferlicot, F Vialard
doi : 10.1093/humrep/deac057
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1334–1350
At present, the only definitive contraindications for TESE in men with non-obstructive azoospermia (NOA) are a 46,XX karyotype and microdeletions in the azoospermia factor a (AZFa) and/or AZFb regions. After a first negative TESE with MA, no test currently exists to predict a negative outcome of a recurrent TESE.
Interaction between cigarette smoking and genetic polymorphisms on the associations with age of natural menopause and reproductive lifespan: the Singapore Chinese Health Study
Zhongwei Huang, Xuling Chang, Ling Wang, Jianjun Liu, Chew-Kiat Heng, Chiea-Chuen Khor, Jian-Min Yuan, Woon-Puay Koh, Rajkumar Dorajoo
doi : 10.1093/humrep/deac075
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1351–1359
Epidemiological data as well as evaluations on genetic predisposition to smoke indicate on the importance of smoking in adverse effects on reproductive lifespan in women. However, there are no previous smoking and gene interaction studies for reproductive traits in East-Asian women.
De novo mutations in children born after medical assisted reproduction
R M Smits, M J Xavier, M S Oud, G D N Astuti, A M Meijerink, P F de Vries, G S Holt, B K S Alobaidi, L E Batty, G Khazeeva, K Sablauskas, L E L M Vissers, C Gilissen, K Fleischer, D D M Braat, L Ramos, J A Veltman
doi : 10.1093/humrep/deac068
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1360–1369
DNMs are known to play a major role in sporadic disorders with reduced fitness such as severe developmental disorders, including intellectual disability and epilepsy.
#ESHREjc report: seeing is believing! How time lapse imaging can improve IVF practice and take it to the future clinic
Munevver Serdarogullari, Omar Farhan Ammar, Kashish Sharma, Florian Kohlhepp, Debbie Montjean, Marcos Meseguer, Juan J Fraire-Zamora
doi : 10.1093/humrep/deac072
Human Reproduction, Volume 37, Issue 6, June 2022, Pages 1370–1372
Correction to: Pubertal development and risk of premenstrual disorders in young adulthood
doi : 10.1093/humrep/deac072
Human Reproduction, Volume 37, Issue 6, June 2022, Page 1373
