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Building Blocks: Studies of Adjunct Perineural vs. Systemic Dexamethasone in Peripheral Nerve Blocks.
Ende, Holly B. 1; Rathmell, James P. 2; Wanderer, Jonathan P. 3
Instructions for Obtaining ANESTHESIOLOGY Continuing Medical Education (CME) Credit.
"People, We Have a Problem".
Sandberg, Warren S. M.D., Ph.D. 1; Davidson, Andrew M.B.B.S., M.D., F.A.N.Z.C.A., F.A.H.M.S. 2
Casting a Wider Net When Fishing for Mechanisms of Anesthesia.
Voss, Logan Ph.D. 1; Sleigh, Jamie W. M.D. 2; Perouansky, Misha M.D. 3
Antiemetic Administration and Its Association with Race: A Retrospective Cohort Study.
White, Robert S. M.D., M.S. 1; Andreae, Michael H. M.D., M.B.A. M.Sc., M.A. 2; Lui, Briana B.S. 3; Ma, Xiaoyue M.S. 4; Tangel, Virginia E. M.A., M.Sc. 5; Turnbull, Zachary A. M.D., M.B.A, M.S. 6; Jiang, Silis Y. Ph.D. 7; Nachamie, Anna S. M.B.A. 8; Pryor, Kane O. M.D. 9; Multicenter Perioperative Outcomes Group Collaborators; Cuff, Germaine B.S.N., Ph.D.; McCormick, Patrick M.D., M.Eng.; Urman, Richard D. M.D., M.B.A.; Pace, Nathan L. M.D., M.Stat.
doi : 10.1097/ALN.0000000000004549
Anesthesiologists' contribution to perioperative healthcare disparities remains unclear because patient and surgeon preferences can influence care choices. Postoperative nausea and vomiting is a patient- centered outcome measure and a main driver of unplanned admissions.
Motor Vehicle Crash Risk among Adults Undergoing General Surgery: A Retrospective Case-crossover Study.
Gaulton, Timothy G. M.D., M.Sc. 1; Pfeiffer, Melissa R. M.P.H. 2; Metzger, Kristina B. Ph.D., M.P.H. 3; Curry, Allison E. Ph.D., M.P.H. 4; Neuman, Mark D. M.D., M.Sc. 5
doi : 10.1097/ALN.0000000000004558
Surgery causes transient impairment in cognition and function, which may impact driving safety. The authors hypothesized that the risk of a motor vehicle crash would increase after compared to before surgery.
Deep Isoflurane Anesthesia Is Associated with Alterations in Ion Homeostasis and Specific Na+/K+-ATPase Impairment in the Rat Brain.
Reiffurth, Clemens Ph.D. 1; Berndt, Nikolaus Ph.D. 2; Gonzalez Lopez, Adrian Ph.D. 3; Schoknecht, Karl M.D., Ph.D. 4; Kovacs, Richard Ph.D. 5; Maechler, Mathilde 6; grote Lambers, Mirja 7; Dreier, Jens P. M.D. 8; Friedman, Alon M.D., Ph.D. 9; Spies, Claudia M.D. 10; Liotta, Agustin M.D. 11
doi : 10.1097/ALN.0000000000004553
Maintenance of ion homeostasis is essential for normal brain function. Inhalational anesthetics are known to act on various receptors, but their effects on ion homeostatic systems, such as sodium/potassium-adenosine triphosphatase (Na+/K+-ATPase), remain largely unexplored.
Perineural and Systemic Dexamethasone and Ulnar Nerve Block Duration: A Randomized, Blinded, Placebo-controlled Trial in Healthy Volunteers.
Maagaard, Mathias M.D. 1; Stormholt, Emma R. B.Sc. 2; Nielsen, Lasse F. M.D. 3; Baerentzen, Finn M.D. 4; Danker, Jakob M.D. 5; Zachodnik, Josephine R.N. 6; Jaeger, Pia M.D., D.M.Sc. 7; Mathiesen, Ole M.D., Ph.D. 8; Andersen, Jakob H. M.D., Ph.D. 9
doi : 10.1097/ALN.0000000000004557
The authors hypothesized that both perineural and systemic dexamethasone as adjuncts to bupivacaine increase the duration of an ulnar nerve block compared with bupivacaine alone, and that systemic dexamethasone is noninferior to perineural dexamethasone.
Phosphorylated Upstream Frameshift 1-dependent Nonsense-mediated [mu]-Opioid Receptor mRNA Decay in the Spinal Cord Contributes to the Development of Neuropathic Allodynia-like Behavior in Rats.
Hsieh, Ming-Chun Ph.D. 1; Lai, Cheng-Yuan Ph.D. 2; Yeh, Chou-Ming M.D., Ph.D. 3; Yang, Po-Sheng M.D., Ph.D. 4; Cheng, Jen-Kun M.D., Ph.D. 5; Wang, Hsueh-Hsiao Ph.D. 6; Lin, Kuan-Hung Ph.D. 7; Nie, Siao-Tong U.G. 8; Lin, Tzer-Bin Ph.D. 9; Peng, Hsien-Yu Ph.D. 10
doi : 10.1097/ALN.0000000000004550
Nonsense-mediated messenger RNA (mRNA) decay increases targeted mRNA degradation and has been implicated in the regulation of gene expression in neurons.
A Chest Tube Inadvertently Inserted into Tracheal Lumen.
Kumar, Nikhil M.D. 1; Gray, Ellyn M.D. 2; King, Alexander M.D. 3; Khanna, Sandeep M.D., F.A.S.A. 4
Is Continuous Intraoperative Monitoring of Mean Arterial Pressure as Good as the Hypotension Prediction Index Algorithm?: Research Letter.
Mulder, Marijn P. M.Sc. 1; Harmannij-Markusse, Mirjam B.Sc.; Donker, Dirk W. M.D., Ph.D.; Fresiello, Libera Ph.D.; Potters, Jan-Willem M.D., Ph.D.
Cohabitation of Neonatally Sevoflurane-exposed and -unexposed Male Rats Affects Their Respective Behavioral Phenotypes: Research Letter.
Ju, Ling-Sha M.S.; Morey, Timothy E. M.D.; Gravenstein, Nikolaus M.D.; Seubert, Christoph N. M.D., Ph.D.; Setlow, Barry Ph.D.; Martynyuk, Anatoly E. Ph.D. 1
Multimodal Analgesic for Knee Arthroplasty: Comment.
Wang, Qiuru M.D.; Hu, Jian M.M.; Kang, Pengde M.D., Ph.D. 1
Neurofilament Light and Cognition after Cardiac Surgery: Comment.
Miles, Lachlan F. Ph.D., F.A.N.Z.C.A. 1; Lankadeva, Yugeesh R. Ph.D.; Sanders, Robert D. Ph.D, F.R.C.A., F.A.N.Z.C.A.; Ayton, Scott Ph.D.
Neurofilament Light and Cognition after Cardiac Surgery: Reply.
Brown, Charles H. IV M.D., M.H.S. 1; Hogue, Charles W. M.D.; Moghekar, Abhay M.D.
Ventilation and Complications after Lung Resection: Comment.
Hoftman, Nir M.D. 1; Umar, Soban M.D., Ph.D.
Ventilation and Complications after Lung Resection: Reply.
Walsh, Spencer P. M.D.; Shaz, David M.D.; Amar, David M.D. 1
Prone Positioning in COVID-19 ARDS: Comment.
Zhao, Zhanqi Ph.D. 1; Frerichs, Inez M.D., Ph.D.
Prone Positioning in COVID-19 ARDS: Reply.
Zarantonello, Francesco M.D.; Sella, Nicolo M.D.; Pettenuzzo, Tommaso M.D.; Boscolo, Annalisa M.D.; Navalesi, Paolo M.D. 1
Saving Grace: What Patients Teach Doctors about Life, Death, and the Balance in Between.
Van Norman, Gail A. M.D. 1
And Finally: Matters of Life and Death.
McGoldrick, Kathryn Elizabeth M.D., F.C.A.I. (Hon.) 1
