Anesthesiology




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Science, Medicine, and the Anesthesiologist.

doi : 10.1097/ALN.0000000000004562

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Carrying Cargo: Preoperative Risk Factors for Persistent Postop Pain & Opioid Use.

Ende, Holly B. 1; Rathmell, James P. 2; Wanderer, Jonathan P. 3

doi : 10.1097/ALN.0000000000004564

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Instructions for Obtaining ANESTHESIOLOGY Continuing Medical Education (CME) Credit.

doi : 10.1097/ALN.0000000000004560

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Uncoupling Pain and Opioid Use after Surgery.

Shiraz Ladha, Karim M.D., M.Sc. 1; Schreiber, Kristin L. M.D., Ph.D. 2

doi : 10.1097/ALN.0000000000004552

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Single-cell Genomics: A Quantum Leap toward Understanding Complexity?.

Vutskits, Laszlo M.D., Ph.D. 1

doi : 10.1097/ALN.0000000000004547

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Prolonged Opioid Use and Pain Outcome and Associated Factors after Surgery under General Anesthesia: A Prospective Cohort Association Multicenter Study.

Kuck, Kai Ph.D. 1; Naik, Bhiken I. M.B.B.Ch., M.S.C.R. 2; Domino, Karen B. M.D., M.P.H. 3; Posner, Karen L. Ph.D. 4; Saager, Leif M.D. 5; Stuart, Ami R. Ph.D. 6; Johnson, Ken B. M.D. 7; Alpert, Salome B. Ph.D. 8; Durieux, Marcel E. M.D., Ph.D. 9; Sinha, Anik K. M.S. 10; Brummett, Chad M. M.D. 11; Aziz, Michael F. M.D. 12; Cummings, Kenneth C. III M.D. 13; Gaudet, John G. M.D. 14; Kurz, Andrea M.D. 15; Rijsdijk, Mienke M.D., Ph.D. 16; Wanderer, Jonathan P. M.D. 17; Pace, Nathan L. M.D., M.Stat. 18; the Multicenter Perioperative Outcomes Group Enhanced Observation Study Investigator Group for the Multicenter Perioperative Outcomes Group Enhanced Observation Study Collaborator Group; Berman, Mitchell F. M.D., M.P.H.; Corradini, Beatriz Raposo M.S.; Mincer, Shawn L. M.S.W; Rose, Sydney E. M.D.; van Klei, Wilton A. M.D., Ph.D.; Edwards, David A. M.D., Ph.D.; Lamers, Olivia O.A. M.D.; Vaughn, Michelle T. M.P.H.

doi : 10.1097/ALN.0000000000004510

There is insufficient prospective evidence regarding the relationship between surgical experience and prolonged opioid use and pain. The authors investigated the association of patient characteristics, surgical procedure, and perioperative anesthetic course with postoperative opioid consumption and pain 3 months postsurgery.

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Single-nucleus Atlas of Sevoflurane-induced Hippocampal Cell Type- and Sex-specific Effects during Development in Mice.

Song, Shao-yong M.D., Ph.D. 1; Peng, Ke M.D., Ph.D. 2; Meng, Xiao-wen Ph.D. 3; Shan, Xi-sheng M.D., Ph.D. 4; Chen, Qing-cai M.D. 5; Zhao, Wei-ming M.D. 6; Shen, Biyu M.D. 7; Qiu, Hong Ph.D. 8; Liu, Hong M.D., FASE 9; Liu, Hua-yue M.D. 10; Ji, Fu-hai M.D., Ph.D. 11

doi : 10.1097/ALN.0000000000004522

Multiple neonatal exposures to sevoflurane induce neurocognitive dysfunctions in rodents. The lack of cell type-specific information after sevoflurane exposure limits the mechanistic understanding of these effects.

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May the-Positive Pressure-Force Be with You, Stephenson Controlled Respiration Unit!

doi : 10.1097/ALN.0000000000004556

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Comparison of Single-operator Laser-assisted Ultrasound-guided Radial Arterial Cannulation in Young Children with Traditional Ultrasound Guidance: A Randomized Clinical Trial.

Hou, Lin M.D. 1; Song, Xuesong M.D., Ph.D. 2; Yan, Na M.D. 3; Zhao, Zhuang M.D. 4; Li, Zhiwen M.D., Ph.D. 5

doi : 10.1097/ALN.0000000000004534

Radial artery cannulation in young children is challenging. A single-operator laser-assisted ultrasound-guidance system was invented to project the path of the target artery on the skin surface.

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Association of Preoperative Growth Differentiation Factor-15 Concentrations and Postoperative Cardiovascular Events after Major Noncardiac Surgery.

Duceppe, Emmanuelle M.D., Ph.D. 1; Borges, Flavia K. M.D., Ph.D. 2; Conen, David M.D. 3; Tiboni, Maria M.D. 4; Chan, Matthew T. V. M.B.B.S., M.Med., Ph.D. 5; Patel, Ameen M.D. 6; Sessler, Daniel I. M.D. 7; Kavsak, Peter A. Ph.D. 8; Ofori, Sandra M.B.B.S., F.W.A.C.P. 9; Srinathan, Sadeesh M.D., M.Sc. 10; Pearse, Rupert M.D. 11; Jaffe, Allan S. M.D. 12; Heels-Ansdell, Diane M.Sc. 13; Garg, Amit X. M.D., Ph.D. 14; Pettit, Shirley R.N. 15; Sapsford, Robert M.B.B.S., M.D. 16; Devereaux, P. J. M.D., Ph.D. 17

doi : 10.1097/ALN.0000000000004539

The association between growth differentiation factor-15 concentrations and cardiovascular disease has been well described. The study hypothesis was that growth differentiation factor-15 may help cardiac risk stratification in noncardiac surgical patients, in addition to clinical evaluation.

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Intravenous Dabigatran Provides Adequate Anticoagulation for Cardiopulmonary Bypass Using a Rabbit Model.

Nadtochiy, Sergiy M. Ph.D. 1; Stefanos, Tatsiana M.D. 2; Angona, Ronald E. M.S., C.C.P. 3; Darrow, Nathan C.C.P. 4; Jones, C.C.P., Karen C.C.P. 5; Feng, Changyong Ph.D. 6; Algahim, Mohamed M.D. 7; LeMoine, Dana D.V.M., M.S., D.A.C.L.A.M. 8; Westcott, Robin B.S., L.V.T. 9; Anderson, Brian M.B. Ch.B, Ph.D. 10; Swartz, Michael F. Ph.D. 11; Eaton, Michael P. M.D., F.A.S.A. 12

doi : 10.1097/ALN.0000000000004537

Heparin anticoagulation has been used successfully for cardiopulmonary bypass (CPB). However, an alternative anticoagulant approach is desirable due to the cases of heparin-induced thrombocytopenia.

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Thrombus Migration Just before Surgery.

Okada, Kosuke M.D. 1; Maeda, Takuma M.D., M.P.H., Ph.D. 2

doi : 10.1097/ALN.0000000000004523

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Perioperative Considerations in Management of the Severely Bleeding Coagulopathic Patient.

Erdoes, Gabor M.D., Ph.D. 1; Faraoni, David M.D., Ph.D. 2; Koster, Andreas M.D. 3; Steiner, Marie E. M.D. 4; Ghadimi, Kamrouz M.D., M.H.Sc., F.A.H.A. 5; Levy, Jerrold H. M.D., F.C.C.M. 6

doi : 10.1097/ALN.0000000000004520

AB Inherited and acquired coagulopathy are frequently associated with major bleeding in severe trauma, cardiac surgery with cardiopulmonary bypass, and postpartum hemorrhage.

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Oxylipin Profiles during the First Day of Mechanical Ventilation in an Intensive Care Unit Cohort: Research Letter.

Larsson, Niklas M.D. 1; Nording, Malin L. Ph.D.; Tyden, Jonas M.D., Ph.D.; Johansson, Joakim M.D., Ph.D.; Lindberg, Richard Ph.D.; Haney, Michael M.D., Ph.D., M.Sc.

doi : 10.1097/ALN.0000000000004518

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Sign-reversed versus Orthodox Granger Causality Analysis of the Electroencephalogram in General Anesthesia: Research Letter.

Sleigh, Jamie W. M.D. 1; Pullon, Rebecca M. Ph.D.

doi : 10.1097/ALN.0000000000004511

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Flow Effects of High-flow Nasal Oxygenation: Comment.

Karim, Habib Reazaul Md M.D., D.N.B., I.D.C.C.M., F.N.I.V. 1; Esquinas, Antonio M. M.D., Ph.D., F.C.C.P., F.A.A.R.C.; O'Brien, Brian F.C.A.R.C.S.I., F.J.F.I.C.M.I., F.C.I.C.M. (A.N.Z.).

doi : 10.1097/ALN.0000000000004540

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Diffusion Limitation of Volatile Anesthetic Uptake: Comment.

Grigoryan, Artush M.D.; Khorasani, Arjang M.D.; Salem, M. Ramez M.D.; Knezevic, Nebojsa Nick M.D., Ph.D. 1

doi : 10.1097/ALN.0000000000004446

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Diffusion Limitation of Volatile Anesthetic Uptake: Reply.

Peyton, Philip J. M.D., Ph.D., M.B.B.S., F.A.N.Z.C.A. 1

doi : 10.1097/ALN.0000000000004447

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Aortic Biomechanics: Comment.

Pagel, Paul S. M.D., Ph.D. 1; Crystal, George J. Ph.D.; Hettrick, Douglas A. Ph.D.

doi : 10.1097/ALN.0000000000004468

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Aortic Biomechanics: Reply.

Gregory, Alexander J. M.D., F.R.C.P.C. 1; Dobson, Gary M. M.D.C.M., M.Sc., F.R.C.P.C.

doi : 10.1097/ALN.0000000000004469

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A Picture Is Worth a Thousand Words: Infographics in the New Era of Medical Education.

Peters, Christine S. M.D. 1; Nordness, Matthew J. M.D.

doi : 10.1097/ALN.0000000000004517

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Bellevue: Three Centuries of Medicine and Mayhem at America's Most Storied Hospital.

Schwartz, Alan Jay M.D., M.S.Ed. 1

doi : 10.1097/ALN.0000000000004507

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Stuck: How Vaccine Rumors Start-and Why They Won't Go Away.

McGoldrick, Kathryn Elizabeth M.D., F.C.A.I. (Hon.) 1

doi : 10.1097/ALN.0000000000004508

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Pharmacodynamic Interaction of Remifentanil and Dexmedetomidine on Depth of Sedation and Tolerance of Laryngoscopy: Erratum.

doi : 10.1097/ALN.0000000000004509

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