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Alternatives to oral mucosa grafts for urethral reconstruction
Angie Lopez Sánchez, Herney Andrés GarcÃÂa-Perdomo & Jaime Andres RobayoÂ
doi : 10.1038/s41585-022-00707-w
Volume 20 Issue 5, May 2023
A sparkling golden anniversary EAU23 Congress sees batons passed in Milan
Annette FennerÂÂ
Using AI to assist pathologists in bladder cancer metastases detection
Maria Chiara MasoneÂÂ
Embryonal origin of adult testicular macrophages
Maria Chiara MasoneÂÂ
Going in circles: circMGA–HNRNPL feedback loop in bladder cancer
Louise StoneÂÂ
The testosterone paradox of advanced prostate cancer: mechanistic insights and clinical implications
Rajendra Kumar, Laura A. Sena, Samuel R. Denmeade & Sushant KachhapÂ
doi : 10.1038/s41585-022-00686-y
The discovery of the benefits of castration for prostate cancer treatment in 1941 led to androgen deprivation therapy, which remains a mainstay of the treatment of men with advanced prostate cancer. However, as early as this original publication, the inevitable development of castration-resistant prostate cancer was recognized. Resistance first manifests as a sustained rise in the androgen-responsive gene, PSA, consistent with reactivation of the androgen receptor axis.
Health-related quality of life after curative treatment for muscle-invasive bladder cancer
Elisabeth Grobet-Jeandin, Ugo Pinar, Jérôme Parra, Morgan Rouprêt & Thomas SeisenÂ
doi : 10.1038/s41585-022-00693-z
Muscle-invasive bladder cancer (MIBC) is an aggressive disease for which the gold-standard treatment is radical cystectomy (RC) in combination with cisplatin-based neoadjuvant chemotherapy. Bladder-sparing strategies such as trimodal therapy (TMT) have also emerged to improve health-related quality of life (HRQoL) of patients.
Lessons learned from the first 15 years of penile transplantation and updates to the Baltimore Criteria
Christopher D. Lopez, Alisa O. Girard, Isabel V. Lake, Byoung Chol Oh, Gerald Brandacher, Damon S. Cooney, Arthur L. Burnett & Richard J. RedettÂ
doi : 10.1038/s41585-022-00699-7
Since 2006, five penis transplants have been performed worldwide. Mixed outcomes have been reported, and two of the five penile transplants have required explantation.
Principles and outcomes of gender-affirming vaginoplasty
Shane D. Morrison, Karel Claes, Martin P. Morris, Stan Monstrey, Piet Hoebeke & Marlon BuncamperÂ
doi : 10.1038/s41585-022-00705-y
Vaginoplasty is the most frequently performed gender-affirming genital surgery for gender-diverse people with genital gender incongruence. The procedure is performed to create an aesthetic and functional vulva and vaginal canal that enables receptive intercourse, erogenous clitoral sensation and a downward-directed urine stream.
