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Dual Sensory Impairment and Perceived Everyday Discrimination in the United States
Ahmed F. Shakarchi, MBChB, MPH; Lama Assi, MD; Joshua R. Ehrlich, MD, MPH; et al.
doi : 10.1001/jamaophthalmol.2020.3982
2020;138(12):1227-1233
Importance Perceived everyday discrimination is a psychosocial stressor linked to adverse health outcomes, including mortality.
Lifetime Outcomes of Anti–Vascular Endothelial Growth Factor Treatment for Neovascular Age-Related Macular Degeneration
Robert P. Finger, MD, PhD; Marie-Therese Puth, MSc; Matthias Schmid, PhD; et al.
doi : 10.1001/jamaophthalmol.2020.3989
2020;138(12):1234-1240
Importance Neovascular age-related macular degeneration (nAMD), the largest single cause of irreversible severe vision loss in high-income countries, can now be treated with vascular endothelial growth factor (VEGF) inhibitors, but to our knowledge, no data on lifetime outcomes are available.
Clinical Phenotype and Course of PDE6A-Associated Retinitis Pigmentosa Disease, Characterized in Preparation for a Gene Supplementation Trial
Laura Kuehlewein, MD; Ditta Zobor, MD; Sten Olof Andreasson, MD, PhD; et al.
doi : 10.1001/jamaophthalmol.2020.4206
2020;138(12):1241-1250
Importance Treatment trials require sound knowledge on the natural course of disease.
Assessment of Pediatric Optic Neuritis Visual Acuity Outcomes at 6 Months
doi : 10.1001/jamaophthalmol.2020.4231
2020;138(12):1253-1261
Importance Optic neuritis (ON) in children is uncommon. There are limited prospective data for visual acuity (VA) outcomes, associated diseases, and neuroimaging findings. Prospective data from a large sample would be useful for counseling families on treatment decisions and prognosis.
Using Optical Coherence Tomography as a Surrogate of Measurements of Intracranial Pressure in Idiopathic Intracranial Hypertension
Vivek Vijay, MD; Susan P. Mollan, MD; James L. Mitchell, MD; et al.
doi : 10.1001/jamaophthalmol.2020.4242
2020;138(12):1264-1271
Importance There is an unmet need for noninvasive biomarkers of intracranial pressure (ICP), which manifests as papilledema that can be quantified by optical coherence tomography (OCT) imaging.
Mesopic and Scotopic Light Sensitivity and Its Microstructural Correlates in Pseudoxanthoma Elasticum
Kristina Hess, MD; Martin Gliem, MD; Peter Charbel Issa, MD, DPhil; et al.
doi : 10.1001/jamaophthalmol.2020.4335
2020;138(12):1272-1279
Importance Correlates for Bruch membrane alterations are needed for interventional trials targeting the Bruch membrane in pseudoxanthoma elasticum (PXE).
Effect of Vitamin D and ?-3 Fatty Acid Supplementation on Risk of Age-Related Macular DegenerationAn Ancillary Study of the VITAL Randomized Clinical Trial
William G. Christen, ScD; Nancy R. Cook, ScD; JoAnn E. Manson, MD, DrPH; et al.
doi : 10.1001/jamaophthalmol.2020.4409
2020;138(12):1280-1289
Importance Observational studies suggest that higher intake or blood levels of vitamin D and marine ?-3 fatty acids may be associated with lower risks of age-related macular degeneration (AMD). However, evidence from randomized trials is limited.
Interaction Between the Distribution of Diabetic Retinopathy Lesions and the Association of Optical Coherence Tomography Angiography Scans With Diabetic Retinopathy Severity
Mohamed Ashraf, MD; Konstantina Sampani, MD; Abdulrahman Rageh, MD; et al.
doi : 10.1001/jamaophthalmol.2020.4516
2020;138(12):1291-1297
Importance Studies have not yet determined whether the distribution of lesions in the retinal periphery alters the association between the severity of diabetic retinopathy (DR) and macular vessel density.
Association of Vision Impairment With Preventive Care Use Among Older Adults in the United States
Lama Assi, MD; Varshini Varadaraj, MD, MPH; Ahmed F. Shakarchi, MD, MPH; et al.
doi : 10.1001/jamaophthalmol.2020.4524
2020;138(12):1298-1306
Importance Preventive care is associated with decreased morbidity and mortality among older adults. Vision impairment may be a barrier to accessing care and health promotion information and therefore may contribute to decreased preventive care uptake.
Self-perception in Preschool Children With Deprivation Amblyopia and Its Association With Deficits in Vision and Fine Motor Skills
Eileen E. Birch, PhD; Yolanda S. Casta?eda, BSN; Christina S. Cheng-Patel, BS, BA; et al.
doi : 10.1001/jamaophthalmol.2020.4363
2020;138(12):1307-1310
Importance Although the development of self-perception and self-esteem has been investigated in children with strabismic and anisometropic amblyopia, we know little about how self-perception is affected in deprivation amblyopia. Deprivation amblyopia from a dense, unilateral cataract is the least common and typically most severe form of amblyopia. After cataract extraction, optical correction, and patching treatment for amblyopia, visual acuity almost always remains abnormal, and except in rare cases, stereoacuity is nearly always nil.
Moving Towards PDE6A Gene Supplementation Therapy
Kinga M. Bujakowska, PhD; Jason Comander, MD, PhD
doi : 10.1001/jamaophthalmol.2020.4216
2020;138(12):1251-1252
Pediatric Optic Neuritis—Building Foundations for a Randomized Clinical Trial
Dan Milea, MD, PhD
doi : 10.1001/jamaophthalmol.2020.4250
2020;138(12):1262-1263
Of Age-Related Macular Degeneration and Vitamins
Robert N. Frank, MD
doi : 10.1001/jamaophthalmol.2020.4417
2020;138(12):1290
Beyond Visual Acuity—The Importance of Studying Motor Skills and Self-perception in Children Treated for Unilateral Congenital Cataract
Carolyn D. Drews-Botsch, PhD, MPH; Scott R. Lambert, MD
doi : 10.1001/jamaophthalmol.2020.4332
2020;138(12):1310-1311
Pepper Spray, Tear Gas, and Rubber Bullets: A Witches’ Brew of Toil and Trouble
Julia A. Haller, MD
doi : 10.1001/jamaophthalmol.2020.4421
2020;138(12):1319-1320
A Woman With Bilateral Visual Field Defects
Andrew M. Williams, MD; Evan L. Waxman, MD, PhD; Tarek A. Shazly, MD, MSc, PhD
doi : 10.1001/jamaophthalmol.2020.2056
2020;138(12):1312-1313
Bilateral Atypical Eyelid Lesions in a 50-Year-Old Woman
Amee D. Azad, BA; Emily S. Charlson, MD, PhD; Andrea L. Kossler, MD
doi : 10.1001/jamaophthalmol.2020.2090
2020;138(12):1314-1315
An Unusual Upper Eyelid Mass
Sarangdev Vaidya, BA; Tatyana Milman, MD; Carol L. Shields, MD
doi : 10.1001/jamaophthalmol.2020.2859
2020;138(12):1316-1317
Epidemiology of Eye Injuries Caused by Personal Protection Devices and Kinetic Impact Projectile Weapons
William R. Bloom, BS; Thomas D. Bloom, MD
doi : 10.1001/jamaophthalmol.2020.4434
2020;138(12):1318-1319
Delayed Recovery of Corneal Nerve Function and Structure Following Acoustic Neuroma Surgery
Mouhamed Al-Aqaba, MD, PhD; Dalia G. Said, MD; Harminder S. Dua, CBE, MD, PhD
doi : 10.1001/jamaophthalmol.2020.4279
2020;138(12):1320-1322
A Case of Metastatic Giant Cell Tumor of Soft Tissue of the Orbit Associated With PALB2 Variant
Fatemeh Rajaii, MD, PhD; Mary E. Aronow, MD; Ashley A. Campbell, MD; et al.
doi : 10.1001/jamaophthalmol.2020.4308
2020;138(12):1322-1324
Iris Metastasis Regression Following Osimertinib Treatment
Kuan-Jen Chen, MD; An-Ning Chao, MD; Chih-Liang Wang, MD
doi : 10.1001/jamaophthalmol.2020.2095
2020;138(12):e202095
Retinal Cavernous Hemangioma With Multiple Saccules Not Filled With Blood
Chung Young Kim, MD; Un Chul Park, MD, PhD
doi : 10.1001/jamaophthalmol.2020.2298
2020;138(12):e202298
Scattered Multilayered Retinal Hemorrhage Secondary to Anterior Chamber Paracentesis, Mimicking a Hematological Disorder
Mingyue Luo, MD; Hong Du, BS; Youxin Chen, MD
doi : 10.1001/jamaophthalmol.2020.2389
2020;138(12):e202389
Bilateral Mantle Cell Lymphoma of the Lacrimal Sac and Nasolacrimal Duct
Antonio A. V. Cruz, MD; Diego M. Gomes, MD; Fernando Chahud, MD
doi : 10.1001/jamaophthalmol.2020.2394
2020;138(12):e202394
