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Editorial introductions.
doi : 10.1097/ICU.0000000000000949
Volume 34(3) pgs. v-vi,189-272 May 2023
The relationship between dietary patterns and ophthalmic disease.
Mulpuri, Lakshman a; Sridhar, Jayanth a; Goyal, Himani b; Tonk, Rahul a
doi : 10.1097/ICU.0000000000000943
There is a rising interest in the impact of diet on the pathogenesis of common ophthalmic conditions. The purpose of this review is to summarize the potential preventive and therapeutic power of dietary interventions described in recent basic science and epidemiological literature.
Identifying geographic atrophy.
Clevenger, Leanne; Rachitskaya, Aleksandra
doi : 10.1097/ICU.0000000000000952
Age-related macular degeneration (AMD) is one of the leading causes of blindness and can progress to geographic atrophy (GA) in late stages of disease.
Novel oral medications for retinal disease: an update on clinical development.
DeBoer, Charles Meno Theodore a; Agrawal, Rajat b; Rahimy, Ehsan a,c
doi : 10.1097/ICU.0000000000000948
Intravitreal and periocular injections for retinal disease provide a targeted delivery of medication to the eye. However, given risks of injections, including endophthalmitis, pain and treatment burden for both patients and retina specialists, there has been significant interest and effort in developing oral medications for the management of retinal disease.
Primary Retinal Detachment Outcomes Study: summary of reports number 1 to number 18.
Starr, Matthew R. a; Ryan, Edwin H. b; Yonekawa, Yoshihiro c
doi : 10.1097/ICU.0000000000000942
To highlight the recent work published from the Primary Retinal Detachment Outcomes (PRO) Study Group. Recent findings: The PRO database was a large dataset made up of patients with primary rhegmatogenous retinal detachments (RRD) who had surgical repair during 2015.
Do published trial results influence physician prescribing patterns? Intravitreal antivascular endothelial growth factor usage by the United States Ophthalmologists before and after Protocol T study.
Shah, Serena a; Markatia, Zahra a; Watane, Arjun b; Feldman, Alexandra a; Shah, Lea a; Sridhar, Jayanth a
doi : 10.1097/ICU.0000000000000944
Clinical trial publications may influence physician prescribing patterns. The Diabetic Retinopathy Clinical Research Network (DRCR.net) Protocol T study, published in 2015, examined outcomes of intravitreal antivascular endothelial growth factor (VEGF) medications for treatment of diabetic macular oedema (DME).
Antisense oligonucleotide therapy for proline-23-histidine autosomal dominant retinitis pigmentosa.
Justin, Grant A. a; Girach, Aniz b; Maldonado, Ramiro S. a
doi : 10.1097/ICU.0000000000000947
To discuss antisense oligonucleotide (ASON) therapy for autosomal dominant retinitis pigmentosa (adRP) caused by the proline-23-histidine (P23H) mutation in the rhodopsin gene.
Recent advances in the management of proliferative diabetic retinopathy.
Pandit, Saagar; Ho, Allen C.; Yonekawa, Yoshihiro
doi : 10.1097/ICU.0000000000000946
The prevalence of diabetic retinopathy continues to rise. This review highlights advances in imaging, medical, and surgical management of proliferative diabetic retinopathy (PDR) in recent years.
Endophthalmitis following cataract surgery: visual outcomes, microbial spectrum and complications.
Levin, Hannah J. a; Mehta, Maitri S. a,b; Storey, Philip P. c; Patel, Samir N. a; Kuley, Brandon a; Wibbelsman, Turner D. a; Obeid, Anthony a; Garg, Sunir a; Vander, James a; Dunn, James P. a; Ho, Allen C. a
doi : 10.1097/ICU.0000000000000951
The aim of this study was to update visual outcomes, microbial spectrum and complications in eyes with endophthalmitis following cataract surgery.
Artificial intelligence in glaucoma: posterior segment optical coherence tomography.
Gutierrez, Alfredo a,b; Chen, Teresa C. b,c
doi : 10.1097/ICU.0000000000000934
To summarize the recent literature on deep learning (DL) model applications in glaucoma detection and surveillance using posterior segment optical coherence tomography (OCT) imaging.
Future of virtual education and telementoring.
Seddon, Ian a,c; Rosenberg, Eric b; Houston, Steve K. III c
doi : 10.1097/ICU.0000000000000945
To summarize recent technological advancements in medical and surgical education and explore what the future of medicine might be as it relates to blockchain technology, the metaverse, and web3.
Assistive applications of artificial intelligence in ophthalmology.
Hubbard, Donald C. a; Cox, Parker b; Redd, Travis K. a
doi : 10.1097/ICU.0000000000000939
Assistive (nonautonomous) artificial intelligence (AI) models designed to support (rather than function independently of) clinicians have received increasing attention in medicine.
Future regenerative therapies for corneal disease.
Lee, John Y. a; Knight, Robert J. a; Deng, Sophie X. a,b
doi : 10.1097/ICU.0000000000000938
To highlight the progress and future direction of stem-cell based regenerative therapies for the treatment of corneal disease Recent findings: Corneal stem cell-based therapies, such as limbal stem cell transplantation, corneal stromal stem cell transplantation, endothelial stem cell transplantation, and stem cell-derived extracellular vesicles have demonstrated promising results in the laboratory.
