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Differing Risks of Occlusive Retinal Vasculitis with Concurrent Intraocular Inflammation Among Intravitreal Antivascular Endothelial Growth Factor Therapies
Schmidt-Ott, Ursula MD*; Hughes, Diana MD†; Chu, Karen MS†; Reed, Kimberly OD†; Leal, Sérgio MD‡; Amer, Fouad MD†; Moini, Hadi PhD†; Bussfeld, Patrick MD‡; Vitti, Robert MD†
doi : 10.1097/IAE.0000000000003015
Retina: April 2021 - Volume 41 - Issue 4 - p 669-670
MANAGEMENT OF RETINAL PIGMENT EPITHELIUM TEAR DURING ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY
Mitchell, Paul MD, PhD*; Rodr?guez, Francisco J. MD†; Joussen, Antonia M. MD‡; Koh, Adrian MBBS, MMed (Ophth), FRCS(Ed), FAMS§; Eter, Nicole MD¶; Wong, David T. MD, FRCSC**; Korobelnik, Jean-François MD††,‡‡; Okada, Annabelle A. MD, DMSc§§
doi : 10.1097/IAE.0000000000003083
Retina: April 2021 - Volume 41 - Issue 4 - p 671-678
This article aims to review current evidence on the development, diagnosis, and management of retinal pigment epithelium (RPE) tear during anti–vascular endothelial growth factor (VEGF) therapy.
CHORIOCAPILLARIS VASCULAR PARAMETERS IN NORMAL EYES AND THOSE WITH PACHYCHOROID WITH AND WITHOUT DISEASE
Spaide, Richard F. MD; Ledesma-Gil, Gerardo MD
doi : 10.1097/IAE.0000000000002988
Retina: April 2021 - Volume 41 - Issue 4 - p 679-685
To evaluate the vascular characteristics of the choriocapillaris in eyes with pachychoroid as compared with normal controls.
CHORIOCAPILLARIS FLOW DEFICITS AS A RISK FACTOR FOR PROGRESSION OF AGE-RELATED MACULAR DEGENERATION
Corvi, Federico MD*,†,‡; Tiosano, Liran MD*,§; Corradetti, Giulia MD*,†; Nittala, Muneeswar Gupta MPhil*; Lindenberg, Sophiana MS*; Alagorie, Ahmed Roshdy MD*,¶; McLaughlin, John Adam MD**; Lee, Thomas K. MD**; Sadda, Srinivas R. MD*,†
doi : 10.1097/IAE.0000000000002990
Retina: April 2021 - Volume 41 - Issue 4 - p 686-693
To evaluate the association between choriocapillaris (CC) flow deficits and structural optical coherence tomography biomarkers and the progression of intermediate age-related macular degeneration (iAMD) to complete retinal pigment epithelial and outer retinal atrophy.
NATURAL HISTORY OF QUANTITATIVE AUTOFLUORESCENCE IN INTERMEDIATE AGE-RELATED MACULAR DEGENERATION
von der Emde, Leon MD*,†; Guymer, Robyn H. MBBS, PhD*,‡; Pfau, Maximilian MD†; Caruso, Emily BOrth*; Sivarajah, Pyrawy BOrth*; Hodgson, Lauren A. B. MPH*; McGuinness, Myra B. MBiostat, PhD*; Sloan, Kenneth R. PhD§; Wu, Zhichao BAppSc(Optom), PhD*,‡
doi : 10.1097/IAE.0000000000002923
Retina: April 2021 - Volume 41 - Issue 4 - p 694-700
To investigate differences in quantitative autofluorescence (qAF) imaging measurements between eyes with and without large drusen, and whether qAF measurements change over time in the eyes with large drusen.
IMPACT OF CORONAVIRUS DISEASE PANDEMIC ON INTRAVITREAL INJECTIONS TREATMENT FOR MACULAR DISEASES
Viola, Francesco MD*; Milella, Paolo MD*; Pozzo Giuffrida, Francesco MD*; Ganci, Simone BSc*; Invernizzi, Alessandro MD†,‡
doi : 10.1097/IAE.0000000000002941
Retina: April 2021 - Volume 41 - Issue 4 - p 701-705
To describe our managing strategy for COVID-19 emergency, to evaluate the adherence to intravitreal treatment (AtT) rate during the outbreak in a referral hospital in Milan, and to correlate it with patients' clinical features.
OUTCOMES OF NONCONFLUENT DIODE LASER PANRETINAL PHOTOCOAGULATION FOR AGGRESSIVE POSTERIOR RETINOPATHY OF PREMATURITY AFTER INTRAVITREAL BEVACIZUMAB
Mammo, Danny A. MD*; Rubino, Shaina M. MD†; Quiram, Polly A. MD, PhD†
doi : 10.1097/IAE.0000000000002943
Retina: April 2021 - Volume 41 - Issue 4 - p 706-710
To assess the safety and efficacy of less dense panretinal photocoagulation after intravitreal bevacizumab in aggressive posterior retinopathy of prematurity infants.
GLYCEMIC VARIABILITY IS ASSOCIATED WITH TREATMENT REQUIRING RETINOPATHY OF PREMATURITY
Jag?a, Mateusz PhD, MD; Szymo?ska, Izabela MD; Starzec, Katarzyna MD; Kwinta, Przemko PhD, MD
doi : 10.1097/IAE.0000000000002949
Retina: April 2021 - Volume 41 - Issue 4 - p 711-717
To assess the association between glycemic variability (GV) and Type 1 retinopathy of prematurity (ROP) in infants with birth weights of less than 1,251 g.
PREOPERATIVE ANATOMICAL FEATURES ASSOCIATED WITH IMPROVED SURGICAL OUTCOMES FOR STAGE 5 RETINOPATHY OF PREMATURITY
Ozsaygili, Cemal MD*,†; Ozdek, Sengul MD*; Ozmen, Mehmet C. MD*; Atalay, Hatice T. MD*; Yeter, Duygu Y. MD*,‡
doi : 10.1097/IAE.0000000000002948
Retina: April 2021 - Volume 41 - Issue 4 - p 718-725
To describe preoperative anatomical features of Stage 5 retinopathy of prematurity with results of surgery and patient-related and surgery-related factors affecting postoperative success.
LONG-TERM SURGICAL OUTCOMES OF LENS CAPSULAR FLAP TRANSPLANTATION IN THE MANAGEMENT OF REFRACTORY MACULAR HOLE
Peng, Jie MD*; Chen, Chunli MD†,‡; Zhang, Hongtao MD§; Zhang, Lihua MD§; Liu, Jingjing MD*; Ren, Jianing MD*; Zhao, Peiquan MD*
doi : 10.1097/IAE.0000000000002922
Retina: April 2021 - Volume 41 - Issue 4 - p 726-734
To report long-term surgical outcomes of autologous and allogenic lens capsular flap transplantation (LCFT) in refractory macular hole (MH) treatment.
HUMAN AMNIOTIC MEMBRANE TO TREAT MACULAR HOLES THAT FAILED TO CLOSE, SULFUR HEXAFLUORIDE ENDOTAMPONADE VERSUS AIR ENDOTAMPONADE
Caporossi, Tomaso MD*; Tartaro, Ruggero MD*; Finocchio, Lucia MD*; Pacini, Bianca MD*; De Angelis, Lorenzo MD*; Bacherini, Daniela MD*; Rizzo, Stanislao MD†
doi : 10.1097/IAE.0000000000002913
Retina: April 2021 - Volume 41 - Issue 4 - p 735-743
To determinate the efficacy of the human amniotic membrane plugs with sulfur hexafluoride versus human amniotic membrane plug with air as endotamponade to treat macular holes that failed to close after vitrectomy plus internal limiting membrane peeling. Multimodal imaging was focused to evaluate preoperative features and postoperative changes.
MULTIFOCAL ELECTRORETINOGRAPHY AND SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IN MACULA-OFF RHEGMATOGENOUS RETINAL DETACHMENT
Kosacki, Julie MD*,†; Gallice, Mathilde MD*,†; Palombi, Karine MD*; Labarere, José MD, PhD†,‡; Creuzot-Garcher, Catherine MD, PhD§; Berthemy-Pellet, Sylvie MD*; Aptel, Florent MD, PhD*,†; Chiquet, Christophe MD, PhD*,†
doi : 10.1097/IAE.0000000000002939
Retina: April 2021 - Volume 41 - Issue 4 - p 744-752
To analyze the temporal trends in structural changes using spectral-domain optical coherence tomography and functional changes using multifocal electroretinogram after rhegmatogenous retinal detachment surgery.
PHACOVITRECTOMY FOR PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT REPAIR
Benson, Matthew D. MD; Sia, David MD; Seamone, Mark E. MSc, MD; Greve, Mark MD; Hinz, Brad MD; Tennant, Matthew T. S. MD; Baker, Chad MD; Somani, Rizwan MD; Ehmann, David S. MD
doi : 10.1097/IAE.0000000000002945
Retina: April 2021 - Volume 41 - Issue 4 - p 753-760
To analyze the single surgery success rate and anterior segment complications related to phacoemulsification and intraocular lens implantation in a series of patients undergoing phacovitrectomy for all types of primary rhegmatogenous retinal detachment.
COMPARISON OF SCLERAL FIXATION OF INTRAOCULAR LENS
Jang, Kyu Hwan MD*; Kong, Mingui MD, PhD*,†; Moon, Byung Gil MD‡; Son, Gisung MD*,†
doi : 10.1097/IAE.0000000000002952
Retina: April 2021 - Volume 41 - Issue 4 - p 761-767
To compare the clinical outcomes of sutured scleral and sutureless intrascleral fixations of the intraocular lens.
MULTIPLE INTRAVITREAL INJECTIONS DO NOT CAUSE ANTERIOR SCLERAL THINNING
Schwartz, Shulamit MD*; Reinhertz, Noa MD†; Neudorfer, Meira MD*; Loewenstein, Anat MD, MHA*; Iglicki, Matias MD‡; Zur, Dinah MD*
doi : 10.1097/IAE.0000000000002951
Retina: April 2021 - Volume 41 - Issue 4 - p 768-773
To evaluate possible changes in anterior scleral thickness and structure and changes in the anterior segment in eyes receiving multiple intravitreal injections using ultrasound biomicroscopy imaging.
BACILLARY LAYER DETACHMENT IN ACUTE VOGT–KOYANAGI–HARADA DISEASE
Agarwal, Aniruddha MD*; Freund, K. Bailey MD†,‡; Kumar, Aman MBBS*; Aggarwal, Kanika MS*; Sharma, Deeksha MBBS*; Katoch, Deeksha MS*; Bansal, Reema MS*; Gupta, Vishali MS*; for the OCTA Study Group
doi : 10.1097/IAE.0000000000002914
Retina: April 2021 - Volume 41 - Issue 4 - p 774-783
To report the frequency, optical coherence tomography (OCT) findings, and visual and anatomic outcomes of patients with acute Vogt–Koyanagi–Harada disease presenting with the bacillary layer detachment (BLD) (intraretinal split at the photoreceptor inner segment myoid).
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FINDINGS OF MICROVASCULAR AND NEURAL CHANGES IN PRIMARY PULMONARY HYPERTENSION
Gu, Simin MD*,†; Li, Zijing MD*,†; Zhang, Yichi MD, PhD*,†; Liu, Yingmei MD, PhD*,†; Zeng, Peng MD*,†; Zeng, Rui MD*,†; Wang, Wenhui MD*,†; Xiao, Jianhui MD, PhD*,†
doi : 10.1097/IAE.0000000000002940
Retina: April 2021 - Volume 41 - Issue 4 - p 784-792
To investigate the microvascular and neural changes in primary pulmonary hypertension (PPH) patients compared with healthy controls.
LONGITUDINAL FOLLOW-UP OF TUBERCULAR SERPIGINOUS-LIKE CHOROIDITIS USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
Agarwal, Aniruddha MD*; Aggarwal, Kanika MS*; Mandadi, Spoorti Krishna Reddy MBBS*; Kumar, Aman MBBS*; Grewal, Dilraj MD†; Invernizzi, Alessandro MD‡,§; Bansal, Reema MS*; Sharma, Aman MD¶; Sharma, Kusum MD**; Gupta, Vishali MS*; for OCTA Study Group
doi : 10.1097/IAE.0000000000002915
Retina: April 2021 - Volume 41 - Issue 4 - p 793-803
To analyze and describe serial follow-up of choriocapillaris alterations in tubercular serpiginouslike choroiditis (SLC) using optical coherence tomography angiography (OCTA) and to compare it with multimodal imaging.
QUANTITATIVE TOPOGRAPHIC CURVATURE MAPS OF THE POSTERIOR EYE UTILIZING OPTICAL COHERENCE TOMOGRAPHY
McNabb, Ryan P. PhD*; Liu, Alice S. BS*; Gospe, Sidney M. III MD, PhD*; El-Dairi, Mays MD*; Meekins, Landon C. MD*; James, Charlene OD*; Vann, Robin R. MD*; Izatt, Joseph A. PhD*,†; Kuo, Anthony N. MD*,†
doi : 10.1097/IAE.0000000000002897
Retina: April 2021 - Volume 41 - Issue 4 - p 804-811
Deformations of the retina such as staphylomas in myopia or scleral flattening in high intracranial pressure can be challenging to quantify with en face imaging. We describe an optical coherence tomography-based method for the generation of quantitative posterior eye topography maps in normal and pathologic eyes.
DIFFERENTIAL RESPONSE TO GLUCOCORTICOID IMMUNOSUPPRESSION OF TWO DISTINCT INFLAMMATORY SIGNS ASSOCIATED WITH PUNCTATE INNER CHOROIDOPATHY
Abdelhakim, Aliaa H. MD, PhD*,†,‡,§; Yannuzzi, Lawrence A. MD*,†,‡,§; Freund, K. Bailey MD*,†,‡,§; Jung, Jesse J. MD¶,**
doi : 10.1097/IAE.0000000000002950
Retina: April 2021 - Volume 41 - Issue 4 - p 812-821
To describe the differential response of two distinct inflammatory signs occurring in eyes with punctate inner choroidopathy.
REFRACTIVE OUTCOMES AFTER SUTURELESS INTRASCLERAL FIXATION OF INTRAOCULAR LENS WITH PARS PLANA VITRECTOMY
Lee, Ramon MD*,†; Govindaraju, Viren MD†; Farley, Nathan D. MD*,†; Abbey, Ashkan M. MD‡; Stem, Maxwell S. MD§; Shields, Ryan A. MD*,†; Wa, Christianne A. MD*,†; Williams, George A. MD*,†; Faia, Lisa J. MD*,†; Hassan, Tarek S. MD*,†; Wolfe, Jeremy D. MD*,†
doi : 10.1097/IAE.0000000000002916
Retina: April 2021 - Volume 41 - Issue 4 - p 822-826
To evaluate the refractive outcomes of sutureless intrascleral fixation of intraocular lens with pars plana vitrectomy.
PARTICULATE MATTER FROM SYRINGES USED FOR INTRAVITREAL INJECTIONS
Dounce, Susan M. PhD*; Laskina, Olga PhD*; Goldberg, Roger A. MD, MBA†
doi : 10.1097/IAE.0000000000002947
Retina: April 2021 - Volume 41 - Issue 4 - p 827-833
Syringes containing anti-vascular endothelial growth factor drugs to treat retinal diseases are prepared in different ways by various parties with syringe selection, preparation, and storage conditions affecting the risk of injecting particles into the vitreous. This study examines particle loads from various syringes over time.
AQUEOUS HUMOR CYTOKINE LEVELS AND REBOUND MACULAR EDEMA AFTER CONBERCEPT TREATMENT IN PATIENTS WITH CENTRAL RETINAL VEIN OCCLUSION
Yang, Kai-Bo MD*; Sun, Xu-Yang MD*,†; Sun, Li-Ping PhD‡; Li, Jun MD*; Liu, Zhe-Li MD, PhD*; Zhang, Han MD, PhD*
doi : 10.1097/IAE.0000000000002918
Retina: April 2021 - Volume 41 - Issue 4 - p 834-843
This study aimed to investigate the effect of intravitreal conbercept (IVC) injections on the aqueous humor concentrations of angiogenic and inflammatory cytokines in patients with macular edema (ME) due to central retinal vein occlusion and to determine whether changes in cytokine levels after IVC are associated with the development of rebound ME.
LONG-TERM EFFECT OF CYSTOTOMY WITH OR WITHOUT THE FIBRINOGEN CLOT REMOVAL FOR REFRACTORY CYSTOID MACULAR EDEMA SECONDARY TO DIABETIC RETINOPATHY
Imai, Hisanori MD, PhD*; Tetsumoto, Akira MD*; Yamada, Hiroko MD*; Hayashida, Mayuka MD*; Otsuka, Keiko MD, PhD*,†; Miki, Akiko MD, PhD*; Kusuhara, Sentaro MD, PhD*; Nakamura, Makoto MD, PhD*
doi : 10.1097/IAE.0000000000002921
Retina: April 2021 - Volume 41 - Issue 4 - p 844-851
To show the long-term effect of cystotomy with or without fibrinogen clot removal for refractory cystoid macular edema secondary to diabetic retinopathy.
MICROSTRUCTURAL CHANGES IN CYSTOID MACULAR EDEMA IN RETINITIS PIGMENTOSA AFTER INTRAVITREAL DEXAMETHASONE IMPLANT INJECTION
Park, Un Chul MD, PhD*,†; Park, Jung Hyun MD, PhD*,‡; Yoon, Chang Ki MD*,†; Yu, Hyeong Gon MD, PhD*,†,§
doi : 10.1097/IAE.0000000000002944
Retina: April 2021 - Volume 41 - Issue 4 - p 852-860
To evaluate microstructural changes in cystoid macular edema in retinitis pigmentosa after intravitreal dexamethasone implant injection.
EVALUATION OF RETINAL VESSEL DIAMETERS IN EYES WITH ACTIVE CENTRAL SEROUS CHORIORETINOPATHY
Altunel, Orhan MD*; Arifoglu, Hasan Basri MD†
doi : 10.1097/IAE.0000000000002932
Retina: April 2021 - Volume 41 - Issue 4 - p 861-866
To compare the retinal vessel diameters of healthy eyes and active central serous chorioretinopathy (CSC) eyes, and to evaluate possible effect of retinal vessel diameter alterations on the pathogenesis of CSC.
GENDER DIFFERENCES IN SELF-REPORTED PROCEDURAL VOLUME AMONG VITREORETINAL FELLOWS
Reyes-Capo, Daniela P. MD*; Yannuzzi, Nicolas A. MD*; Chan, R.V. Paul MD†; Murray, Timothy G. MD, MBA‡; Berrocal, Audina M. MD*; Sridhar, Jayanth MD*
doi : 10.1097/IAE.0000000000002942
Retina: April 2021 - Volume 41 - Issue 4 - p 867-871
A prior study revealed discrepancies in self-reported surgical numbers between male and female ophthalmology residents. This study further investigates the gender differences in self-reported procedural volume among vitreoretinal surgery fellows and examines the differences for surgical, medical, and total self-reported procedural volume between male and female vitreoretinal fellows.
DEEP PHENOTYPING AND FURTHER INSIGHTS INTO ITM2B-RELATED RETINAL DYSTROPHY
Nassisi, Marco MD, MSc*,†; Wohlschlegel, Juliette MSc*; Liu, Bingqian MSc*; Letellier, Camille MSc*; Michiels, Christelle BSc*; Aubois, Anne MD†; Mohand-Said, Saddek MD, PhD*,†; Habas, Christophe MD, PhD‡; Sahel, José-Alain MD*,†,§,¶,**; Zeitz, Christina PhD*; Audo, Isabelle MD, PhD*,†,††
doi : 10.1097/IAE.0000000000002953
Retina: April 2021 - Volume 41 - Issue 4 - p 872-881
To reappraise the presentation and the course of ITM2B-related retinal dystrophy and give further insights into ITM2B expression in the retina.
Diagnostic and Therapeutic Challenges
Ledesma-Gil, Gerardo Drs.; Freund, K. Bailey; Sherman, Jerome; T. Moore, Anthony
doi : 10.1097/IAE.0000000000002749
Retina: April 2021 - Volume 41 - Issue 4 - p 882-885
OMNIDIRECTIONAL ILLUMINATION LIGHT SOURCE DEVICE
Torii, Hideo MD*; Noma, Hidetaka MD†; Miike, Shinya‡
doi : 10.1097/IAE.0000000000003062
Retina: April 2021 - Volume 41 - Issue 4 - p 886-889
VITREOUS SEEDING OF CHOROIDAL MELANOMA
Raval, Vishal MD*; Bowen, Randy C. MD, MS*; Soto, Hansell MD*; Biscotti, Charles MD†; Yeaney, Gabrielle MD†; Sears, Jonathan MD‡; Singh, Arun MD*
doi : 10.1097/IAE.0000000000002989
Retina: April 2021 - Volume 41 - Issue 4 - p 890-894
To report a case of vitreous seeding in a medium-sized choroidal melanoma and review the literature.
