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Long COVID: Does SARS-CoV-2 induce lingering brain lesions?
Hundreds of millions of COVID cases have been reported so far and long-term lingering clinical symptoms are frequent and are called long COVID. Neurological signs including cognitive complaints are often described in long Covid.
doi : 10.1111/ene.15751
Hundreds of millions of COVID cases have been reported so far and long-term lingering clinical symptoms are frequent and are called long COVID. Neurological signs including cognitive complaints are often described in long Covid.
Autoimmune encephalitis: Should we consider third-line immunotherapies earlier?
Mark J Kelly, Sarosh R. Irani
doi : 10.1111/ene.15728
Cardiovascular autonomic dysfunction: A cause of acute COVID-19 complications and persistent post-COVID-19 complaints?
Max J. Hilz
doi : 10.1111/ene.15719
Contraintuitive fallacy in a big-risk-no-gain stroke scenario? Please verify!
Peter D. Schellinger
doi : 10.1111/ene.15747
Association of regional white matter hyperintensities with hypertension and cognition in the population-based 1000BRAINS study
Janine Gronewold, Martha Jokisch, Sara Schramm, Heiko Himpfen, Theresa Ginster, Isabell Tenhagen, Thorsten R. Doeppner, Christiane Jockwitz, Tatiana Miller, Nils Lehmann, Susanne Moebus, Karl-Heinz Jöckel, Raimund Erbel, Svenja Caspers, Dirk M. Hermann, the Heinz Nixdorf Recall Study Investigative Group
doi : 10.1111/ene.15716
White matter hyperintensities of presumed vascular origin (WMH) are frequent in cerebral magnetic resonance imaging of older people. They are promoted by vascular risk factors, especially hypertension, and are associated with cognitive deficits at the group level. It has been suggested that not only the severity, but also the location, of lesions might critically influence cognitive deficits and represent different pathologies.
Socioeconomic status as a risk factor for motoric cognitive risk syndrome in a community-dwelling population: A longitudinal observational study
Donncha S. Mullin, Lucy E. Stirland, Tom C. Russ, Michelle Luciano, Graciela Muniz-Terrera
doi : 10.1111/ene.15731
Motoric cognitive risk (MCR) is a syndrome characterised by measured slow gait speed and self-reported cognitive complaints. MCR is a high-risk state for adverse health outcomes in older adults, particularly cognitive impairment and dementia. Previous studies have identified risk factors for MCR, but the effect of socioeconomic status has, to date, been insufficiently examined.
Associations of Life's Simple 7 with cerebral white matter hyperintensities and microstructural integrity: UK Biobank cohort study
Yan Fu, Yan Sun, Zhi-Bo Wang, Dan-Dan Zhang, Lan Tan, Jian-Feng Feng, Wei Cheng, Jin-Tai Yu
doi : 10.1111/ene.15750
The American Heart Association Life's Simple 7 (LS7) metric was used to define optimal cardiovascular and brain health, but the associations with macrostructural hyperintensities and microstructural white matter damage are unclear. The objective was to determine the association of LS7 ideal cardiovascular health factors with macrostructural and microstructural integrity.
Clinicopathological associations of hemispheric dominance in primary progressive apraxia of speech
Carling G. Robinson, Joseph R. Duffy, Heather A. Clark, Rene L. Utianski, Mary M. Machulda, Hugo Botha, Neha Atulkumar Singh, Nha Trang Thu Pham, Nilufer Ertekin-Taner, Dennis W. Dickson, Val J. Lowe, Jennifer L. Whitwell, Keith A. Josephs
doi : 10.1111/ene.15764
Primary progressive apraxia of speech (PPAOS) is associated with imaging abnormalities in the lateral premotor cortex (LPC) and supplementary motor area (SMA). It is not known whether greater involvement of these regions in either hemisphere is associated with demographics, presenting, and/or longitudinal features.
Severity of in vivo corticospinal tract degeneration is associated with survival in amyotrophic lateral sclerosis: a longitudinal, multicohort study
Daniel Ta, Abdullah H. Ishaque, Adam Elamy, Tanushka Anand, Andrew Wu, Dean T. Eurich, Collin Luk, Yee Hong Yang, Sanjay Kalra
doi : 10.1111/ene.15686
This study sought to evaluate the relationship of progressive corticospinal tract (CST) degeneration with survival in patients with amyotrophic lateral sclerosis (ALS).
Not a benign motor neuron disease: longitudinal imaging captures relentless motor connectome disintegration in primary lateral sclerosis
Marlene Tahedl, Ee Ling Tan, Stacey Li Hi Shing, Rangariroyashe H. Chipika, We Fong Siah, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Eoin Finegan, Peter Bede
doi : 10.1111/ene.15725
Primary lateral sclerosis (PLS) is a progressive upper motor neuron disorder associated with considerable clinical disability. Symptoms are typically exclusively linked to primary motor cortex degeneration and the contribution of pre-motor, supplementary motor, cortico-medullary and inter-hemispheric connectivity alterations are less well characterized.
Evaluating the contribution of the gene TARDBP in Italian patients with amyotrophic lateral sclerosis
Serena Lattante, Mario Sabatelli, Giulia Bisogni, Giuseppe Marangi, Paolo Niccolò Doronzio, Francesco Martello, Anna Gloria Renzi, Elda Del Giudice, Alberta Leon, Paola Cimbolli, Daniela Marchione, Umberto Costantino, Gabriele Lucioli, Daniela Bernardo, Emiliana Meleo, Agata Katia Patanella, Angela Romano, Marcella Zollino, Amelia Conte
doi : 10.1111/ene.15727
Genetic variants in the gene TARDBP, encoding TDP-43 protein, are associated with amyotrophic lateral sclerosis (ALS) in familial (fALS) and sporadic (sALS) cases. Objectives of this study were to assess the contribution of TARDBP in a large cohort of Italian ALS patients, to determine the TARDBP-associated clinical features and to look for genotype–phenotype correlation and penetrance of the mutations.
Association of biallelic RFC1 expansion with early-onset Parkinson's disease
Pauli Ylikotila, Jussi Sipilä, Tiina Alapirtti, Riitta Ahmasalo, Eriko Koshimizu, Satoko Miyatake, Anri Hurme-Niiranen, Ari Siitonen, Hiroshi Doi, Fumiaki Tanaka, Naomichi Matsumoto, Kari Majamaa, Laura Kytövuori
doi : 10.1111/ene.15717
The biallelic repeat expansion (AAGGG)exp in the replication factor C subunit 1 gene (RFC1) is a frequent cause of cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS) as well as late-onset ataxia.
Speech biomarkers in Huntington's disease: A cross-sectional study in pre-symptomatic, prodromal and early manifest stages
Tomas Kouba, Wiebke Frank, Tereza Tykalova, Alzbeta Mühlbäck, JiřàKlempÃÂÃ…â„¢, Katrin S. Lindenberg, G. Bernhard Landwehrmeyer, Jan Rusz
doi : 10.1111/ene.15726
Motor speech alterations are a prominent feature of clinically manifest Huntington's disease (HD). Objective acoustic analysis of speech can quantify speech alterations. It is currently unknown, however, at what stage of HD speech alterations can be reliably detected.
Parkinson disease following COVID-19: Report of six cases
Alessandra Calculli, Tommaso Bocci, Mattia Porcino, Micol Avenali, Chiara Casellato, Sebastiano Arceri, Simone Regalbuto, Alberto Priori, Antonio Pisani
doi : 10.1111/ene.15732
Core clinical manifestations of COVID-19 include influenza-like and respiratory symptoms. However, it is now evident that neurological involvement may occur during SARS-CoV-2 infection, covering an extensive spectrum of phenotypical manifestations.
Two-Year observational study of autonomic skin function in patients with Parkinson's disease compared to healthy individuals
Timo Siepmann, Martin Arndt, Annahita Sedghi, Szabolcs Szatmári Jr, Tamás Horváth, Annamária Takáts, Dániel Bereczki, Mats Leif Moskopp, Sylvia Buchmann, Cornelia Skowronek, Wagner Zago, Warunya Woranush, Razvan Lapusca, Marie Luise Weidemann, Christopher H. Gibbons, Roy Freeman, Heinz Reichmann, Volker Puetz, Kristian Barlinn, Alexandra Pintér, Ben Min-Woo Illigens
doi : 10.1111/ene.15733
We characterized autonomic pilomotor and sudomotor skin function in early Parkinson's disease (PD) longitudinally.
Endovascular thrombectomy for basilar artery occlusion stroke: Analysis of the German Stroke Registry-Endovascular Treatment
Katharina Feil, Maria Teresa Berndt, Silke Wunderlich, Christian Maegerlein, Kathleen Bernkopf, Hanna Zimmermann, Moriz Herzberg, Steffen Tiedt, Clemens Küpper, Johannes Wischmann, Sonja Schönecker, Konstantin Dimitriadis, Thomas Liebig, Marianne Dieterich, Claus Zimmer, Lars Kellert, Tobias Boeckh-Behrens, for the GSR Investigators
doi : 10.1111/ene.15694
Acute ischemic stroke due to basilar artery occlusion (BAO) causes the most severe strokes and has a poor prognosis. Data regarding efficacy of endovascular thrombectomy in BAO are sparse. Therefore, in this study, we performed an analysis of the therapy of patients with BAO in routine clinical practice.
Risk of poststroke epilepsy after reperfusion therapies: AÂ national cohort study
Hanna Eriksson, Annika Nordanstig, Alexandros Rentzos, Johan Zelano, Petra Redfors
doi : 10.1111/ene.15695
The risk of poststroke epilepsy (PSE) after endovascular treatment (EVT) is not well characterized. In this nationwide study, we assessed the risk of PSE after EVT and identified associated predictors.
Intravenous thrombolysis + endovascular thrombectomy versus thrombolysis alone in large vessel occlusion mild stroke: a propensity score matched analysis
Ghil Schwarz, Sara Bonato, Silvia Lanfranconi, Marius Matusevicius, Isabella Ghione, Gloria Valcamonica, Georgios Tsivgoulis, Ana Paiva Nunes, Michelangelo Mancuso, Andrea Zini, Paolo Candelaresi, Viiu-Marika Rand, Giacomo P. Comi, Michael V. Mazya, Niaz Ahmed
doi : 10.1111/ene.15722
The best reperfusion treatment for patients with mild acute ischaemic stroke harbouring proximal anterior circulation large vessel occlusion (LVO) is unknown. The aim was to compare the safety and efficacy of intravenous thrombolysis (IVT) plus endovascular thrombectomy (EVT) versus IVT alone in LVO patients with mild symptoms.
Sequential detection rates of intramural hematoma for diagnosing spontaneous intracranial artery dissection
Satoshi Hosoki, Mayumi Fukuda-Doi, Kaori Miwa, Sohei Yoshimura, Yoshiaki Morita, Tetsuya Chiba, Kotaro Noda, Yoshitaka Yamaguchi, Hajime Ikenouchi, Naoki Makita, Tadataka Mizoguchi, Yuki Nakamura, Tetsu Satow, Hiroharu Kataoka, Kazunori Toyoda, Masafumi Ihara, Masatoshi Koga
doi : 10.1111/ene.15715
Spontaneous intracranial artery dissection (IAD) can be definitively diagnosed by detecting intramural hematoma (IMH) on arterial wall imaging. However, evidence of a time-dependent natural history for the development of radiological findings is lacking. Therefore, this study aimed to determine when imaging detects IAD.
Association between proprotein convertase subtilisin/kexin type 9 and subclinical cerebrovascular disease in the community
Ayako Kunimura, Yuichiro Yano, Takashi Hisamatsu, Sayuki Torii, Keiko Kondo, Aya Kadota, Akira Fujiyoshi, Tomonori Okamura, Yoshiyuki Watanabe, Akihiko Shiino, Kazuhiko Nozaki, Hirotsugu Ueshima, Katsuyuki Miura, the SESSA research group
doi : 10.1111/ene.15723
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a new target for reducing low-density lipoprotein cholesterol and incident cardiovascular disease, including stroke.
Decompressive surgery in cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia
Katarzyna Krzywicka, Diana Aguiar de Sousa, Charlotte Cordonnier, Felix J. Bode, Thalia S. Field, Dominik Michalski, Johann Pelz, Mona Skjelland, Markus Wiedmann, Julian Zimmermann, Matthias Wittstock, Bruno Zanotti, Alfonso Ciccone, Monica Bandettini di Poggio, Afshin Borhani-Haghighi, Sophie Chatterton, Avinash Aujayeb, Annemie Devroye, Vanessa Dizonno, Thomas Geeraerts, Fabrizio Giammello, Albrecht Günther, Nasli R. Ichaporia, Timothy Kleinig, Espen S. Kristoffersen, Robin Lemmens, Emmanuel De Maistre, Zahra Mirzaasgari, Jean-Francois Payen, Jukka Putaala, Marco Petruzzellis, Nicolas Raposo, Elyar Sadeghi-Hokmabadi, Silvia Schoenenberger, Meenakshisundaram Umaiorubahan, Padmavathy N Sylaja, Anita van de Munckhof, Mayte Sánchez van Kammen, Erik Lindgren, Katarina Jood, Adrian Scutelnic, Mirjam R. Heldner, Sven Poli, Marieke J. H. A. Kruip, Antonio Arauz, Adriana B. Conforto, Sanjith Aaron, Saskia Middeldorp, Turgut Tatlisumak, Marcel Arnold, Jonathan M. Coutinho, José M. Ferro, Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group
doi : 10.1111/ene.15735
Cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia (CVST-VITT) is an adverse drug reaction occurring after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination.
Modifiable vascular risk factors in patients with cerebral and spinal cavernous malformations: a complete 10-year follow-up study
Steffen Rauscher, Alejandro N. Santos, Hanah Hadice Gull, Laurèl Rauschenbach, Bixia Chen, Börge Schmidt, Cornelius Deuschl, Arnau Benet, Ramazan Jabbarli, Karsten H. Wrede, Adrian M. Siegel, Michael Lawton, Ulrich Sure, Philipp Dammann
doi : 10.1111/ene.15737
The aim was to investigate the effect of modifiable vascular risk factors on the risk of first and recurrent bleeding for patients with a cavernous malformation (CM) of the central nervous system (CNS) over a 10-year period.
Biomarkers predictive of atrial fibrillation in patients with cryptogenic stroke. Insights from the Nordic Atrial Fibrillation and Stroke (NOR-FIB) study
Anna Tancin Lambert, Barbara Ratajczak-Tretel, Riadh Al-Ani, Kathrine Arntzen, Grete Kristin Bakkejord, Hanna Marie Otterholt Bekkeseth, Vigdis Bjerkeli, Guttorm Eldøen, Anne Kristine Gulsvik, Bente Halvorsen, Gudrun Anette Høie, Hege Ihle-Hansen, HÃ¥kon Ihle-Hansen, Susanne Ingebrigtsen, Henriette Johansen, Christine Kremer, Siv Bohne Krogseth, Christina Kruuse, Martin Kurz, Ingvild Nakstad, Vojtech Novotny, Halvor Næss, Rehman Qazi, Mehdi Kallaj Rezai, Dag Marius Rørholt, Linn Hofsøy Steffensen, Jesper Sømark, HÃ¥kon Tobro, Thomas Clement Truelsen, Lejla Wassvik, Karen Lehrmann Ægidius, Maiju Pesonen, Mirko de Melis, Dan Atar, Anne Hege Aamodt, NOR-FIB Study Group
doi : 10.1111/ene.15746
There are currently no biomarkers to select cryptogenic stroke (CS) patients for monitoring with insertable cardiac monitors (ICMs), the most effective tool for diagnosing atrial fibrillation (AF) in CS. The purpose of this study was to assess clinically available biomarkers as predictors of AF.
Functional outcome after initial and multiple intracerebral hemorrhages in children with cerebral cavernous malformations
Alejandro N. Santos, Laurèl Rauschenbach, Hannah Hadice Gull, Thiemo Florin Dinger, Mehdi Chihi, Yan Li, Stephan Tippelt, Christian Dohna-Schwake, Börge Schmidt, Ramazan Jabbarli, Karsten H. Wrede, Ulrich Sure, Philipp Dammann
doi : 10.1111/ene.15749
We aimed to assess the course and predictors of functional outcome after single and multiple intracerebral hemorrhage (ICH) in pediatric patients with cerebral cavernous malformations (CCMs) and to conduct a risk assessment of a third bleed during the first follow-up year after second ICH.
Plasma neurofilament light significantly decreases following treatment in Lyme neuroborreliosis and is not associated with persistent symptoms
Helene Mens, Lasse Fjordside, Rosa Gynthersen, Mathilde Ørbæk, Åse Bengaard Andersen, Ulf Andreasson, Kaj Blennow, Finn Sellebjerg, Henrik Zetterberg, Anne-Mette Lebech
doi : 10.1111/ene.15707
Currently there is an unmet need for a highly standardized blood biomarker test to monitor treatment response in Lyme neuroborreliosis (LNB).
Cortical lesions at diagnosis predict long-term cognitive impairment in multiple sclerosis: A 20-year study
Stefano Ziccardi, Anna Isabella Pisani, Gian Marco Schiavi, Maddalena Guandalini, Francesco Crescenzo, Annalisa Colombi, Angela Peloso, Agnese Tamanti, Maddalena Bertolazzo, Damiano Marastoni, Massimiliano Calabrese
doi : 10.1111/ene.15697
Although cognitive impairment (CI) is frequent in multiple sclerosis (MS) patients, few studies (and with conflicting results) have evaluated early predictors of CI in the long term. We aimed at determining associations between early clinical/neuroradiological variables with reference to CI after 20 years of MS.
High serum neurofilament light chain levels correlate with brain atrophy and physical disability in multiple sclerosis
Arabella Buchmann, Lukas Pirpamer, Daniela Pinter, Margarete Voortman, Birgit Helmlinger, Alexander Pichler, Aleksandra Maleska Maceski, Pascal Benkert, Gerhard Bachmaier, Stefan Ropele, Markus Reindl, David Leppert, Jens Kuhle, Christian Enzinger, Michael Khalil
doi : 10.1111/ene.15742
Serum neurofilament light chain (sNfL) is a promising biomarker of neuroaxonal damage in persons with multiple sclerosis (pwMS). In cross-sectional studies, sNfL has been associated with disease activity and brain magnetic resonance imaging (MRI) changes; however, it is still unclear to what extent in particular high sNfL levels impact on subsequent disease evolution.
Immunization status in patients with multiple sclerosis: AÂ cross-sectional, monocenter study in Austria
Klaus Berek, Philipp Deisl, Maximilian Bichler, Michael Auer, Robert Barket, Angelika Bauer, Anne Zinganell, Franziska Di Pauli, Florian Deisenhammer, Harald Hegen
doi : 10.1111/ene.15748
Patients with multiple sclerosis (MS) under certain disease-modifying therapies (DMT) show a higher risk of infection and a lower immune response to vaccination. Hence, assessing immunization status prior to DMT start and, where necessary, performing vaccinations is recommended. We aimed to determine the immunization status in MS patients and to identify factors associated with low vaccination rates.
Complement activation profiles in anti-acetylcholine receptor positive myasthenia gravis
Frauke Stascheit, Omar Chuquisana, Christian W. Keller, Philip Alexander Ambrose, Sarah Hoffmann, Catharina C. Gross, Sophie Lehnerer, Heinz Wiendl, Nick Willcox, Andreas Meisel, Jan D. Lünemann
doi : 10.1111/ene.15730
Complement component 5 (C5) targeting therapies are clinically beneficial in patients with acetylcholine receptor antibody+ (AChR-Ab+) generalized myasthenia gravis (MG). That clearly implicates antibody-mediated complement activation in MG pathogenesis. Here, classical and alternative complement pathways were profiled in patients from different MG subgroups.
Phase 2 trial in acetylcholine receptor antibody-positive myasthenia gravis of transition from intravenous to subcutaneous immunoglobulin: The MGSCIg study
Mamatha Pasnoor, Vera Bril, Todd Levine, Jaya Trivedi, Nicholas J. Silvestri, Milind Phadnis, Hans D. Katzberg, David S. Saperstein, Gil I. Wolfe, Laura Herbelin, Kiley Higgs, Andrew J. Heim, Jeffrey M. Statland, Richard J. Barohn, Mazen M. Dimachkie
doi : 10.1111/ene.15745
Data on maintenance therapy with subcutaneous immunoglobulin (SCIg) in myasthenia gravis (MG) are limited. We report on transitioning acetylcholine receptor (AChR) antibody-positive (Ab+) MG patients on stable intravenous immunoglobulin (IVIg) regimens as part of routine clinical care to SCIg 1:1.2.
Cluster headache polygenetic risk and known functional variants of CYP3A4 are not associated with treatment response
Anja Sofie Petersen, Mads Barloese, Nunu Lund, Adam Friis Pedersen, Marie-Louise Kulas Søborg, Mona Ameri Chalmer, Ida Callesen, Bendik Slagsvold Winsvold, John-Anker Zwart, DBDS Genomic Consortium, Sisse Rye Ostrowski, Ole Birger Pedersen, Finn Sellebjerg, Helle Bach Søndergaard, Malene Bredahl Hansen, Rigmor Højland Jensen, Thomas Folkmann Hansen
doi : 10.1111/ene.15736
The response to cluster headache treatments has a high interindividual variation. To date, treatment response has only been assessed by a candidate gene approach and no investigations into metabolic pathways have been performed.
Efficacy and safety of fremanezumab for migraine prophylaxis in patients with at least three previous preventive failures: Prospective, multicenter, real-world data from a Greek registry
Andreas A. Argyriou, Emmanouil V. Dermitzakis, Georgia Xiromerisiou, Dimitrios Rallis, Panagiotis Soldatos, Pantelis Litsardopoulos, Michail Vikelis
doi : 10.1111/ene.15740
To prospectively assess the efficacy and safety of fremanezumab for migraine prophylaxis in patients with failure of at least three previous preventive treatments. Changes in disability as quality-of-life outcomes after fremanezumab treatment were also examined.
Site matters: Central neuropathic pain characteristics and somatosensory findings after brain and spinal cord lesions
Luciana Mendonça Barbosa, Fernanda Valerio, Samira Luisa Apóstolos Pereira, ValquÃria Aparecida da Silva, Antônia Lilian de Lima Rodrigues, Ricardo Galhardoni, Lin Tchia Yeng, Jefferson Rosi Jr., Adriana Bastos Conforto, Leandro Tavares Lucato, Marcelo Delboni Lemos, Manoel Jacobsen Teixeira, Daniel Ciampi de Andrade
doi : 10.1111/ene.15744
It is unknown if different etiologies or lesion topographies influence central neuropathic pain (CNP) clinical manifestation.
Role of selective attention in fatigue in neurological disorders
Annapoorna Kuppuswamy
doi : 10.1111/ene.15739
Chronic fatigue is a significant symptom in several diseases including traumatic and degenerative neurological disorders. While several studies have investigated the correlates of chronic fatigue, there is as yet no unifying framework to explain chronic fatigue.
Time for optimism in amyotrophic lateral sclerosis
Philippe Corcia, Christian Lunetta, Patrick Vourc'h, Pierre-François Pradat, Hélène Blasco
doi : 10.1111/ene.15738
Gastrointestinal barriers to levodopa transport and absorption in Parkinson's disease
Valentina Leta, Lisa Klingelhoefer, Katherine Longardner, Marta Campagnolo, Hafize Çotur Levent, Federico Aureli, Vinod Metta, Roongroj Bhidayasiri, Guy Chung-Faye, Cristian Falup-Pecurariu, Fabrizio Stocchi, Peter Jenner, Tobias Warnecke, K. Ray Chaudhuri, International Parkinson and Movement Disorders Society Non-Motor Parkinson's Disease Study Group
doi : 10.1111/ene.15734
Levodopa is the gold standard for the symptomatic treatment of Parkinson's disease (PD). There are well documented motor and non-motor fluctuations, however, that occur almost inevitably once levodopa is started after a variable period in people with PD.
A systematic review and meta-analysis of respiratory dysfunction in Parkinson's disease
Laura McMahon, Catherine Blake, Olive Lennon
doi : 10.1111/ene.15743
Respiratory dysfunction in Parkinson's disease (PD) is common and associated with increased hospital admission and mortality rates. Central and peripheral mechanisms have been proposed in PD. To date no systematic review identifies the extent and type of respiratory impairments in PD compared with healthy controls.
Functional neurological disorder in people with long COVID: AÂ systematic review
Tiago Teodoro, Jiaying Chen, Jeannette Gelauff, Mark J. Edwards
doi : 10.1111/ene.15721
Acute health events, including infections, can trigger the onset of functional neurological disorder (FND). It was hypothesized that a proportion of people with long COVID might be experiencing functional symptoms.
Non-ADEM encephalitis in patients with myelin oligodendrocyte glycoprotein antibodies: a systematic review
Enrique Vega, Georgina Arrambide, Gemma Olivé, Mireia Castillo, Ana Felipe-Rucián, Mar Tintoré, Xavier Montalban, Carmen Espejo, MarÃÂa Sepúlveda, Thais Armangué, Alvaro Cobo-Calvo
doi : 10.1111/ene.15684
Non-(acute disseminated encephalomyelitis) (non-ADEM) encephalitis and/or fluid attenuated inversion recovery hyperintense lesions in anti-myelin-oligodendrocyte-glycoprotein-associated encephalitis with seizures (FLAMES) are rarely described in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies (Abs).
Clinical presentation and management strategies of cardiovascular autonomic dysfunction following a COVID-19 infection – A systematic review
Diogo Reis Carneiro, Isabel Rocha, Mario Habek, Raimund Helbok, Johann Sellner, Walter Struhal, Gregor Wenning, Alessandra Fanciulli
doi : 10.1111/ene.15714
Cardiovascular autonomic dysfunction may reportedly occur after a coronavirus-disease-2019 (COVID-19) infection, but the available evidence is scattered. Here we sought to understand the acute and mid-term effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on cardiovascular autonomic function.
Relationship between psychosocial and psychiatric risk factors and poor long-term outcome following mild traumatic brain injury: A systematic review
Martijn de Neeling, Dirk Liessens, Bart Depreitere
doi : 10.1111/ene.15713
Mild traumatic brain injury (mTBI) has an estimated worldwide incidence of >60 million per year, and long-term persistent postconcussion symptoms (PPCS) are increasingly recognized as being predicted by psychosocial variables.
Letter to the editor in response to ‘Hepatitis E virus and Bell's palsy’
JoaquÃÂn Bravo Urbieta, Miguel MartÃÂn Cascón, Sergio Alemán Belando
doi : 10.1111/ene.15724
